| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mohaya Farzin, Shahin Hassanpour, Morteza Zendehdel, Bita Vazir, Ahmad Asghar. Effects of Intracerebroventricular Injection of Spexin and its Interaction with NPY, GalR Neuroscience letters. 2022-03-29. PMID:35346778. |
therefore, the aim of this study was to investigate the effects of icv injection of spexin and its interaction with galr and npy receptors on central food intake regulation and nutritional behavior in broiler chickens. |
2022-03-29 |
2023-08-13 |
chicken |
| Lola Torz, Kristoffer Niss, Sofia Lundh, Jens C Rekling, Carlos Damian Quintana, Signe Emilie Dannulat Frazier, Aaron J Mercer, Anda Cornea, Charlotte Vinther Bertelsen, Marina Kjærgaard Gerstenberg, Ann Maria Kruse Hansen, Mette Guldbrandt, Jens Lykkesfeldt, Linu Mary John, J Carlos Villaescusa, Natalia Peterse. NPFF Decreases Activity of Human Arcuate NPY Neurons: A Study in Embryonic-Stem-Cell-Derived Model. International journal of molecular sciences. vol 23. issue 6. 2022-03-25. PMID:35328681. |
animal studies showed that neuropeptide ff (npff) reduces food intake by its action in neuropeptide y (npy) neurons of the hypothalamic arc, but the detailed mode of action observed in human neurons is missing, due to the lack of a human-neuron-based model for pharmacology testing. |
2022-03-25 |
2023-08-13 |
human |
| Gonzalo de Alba, Sherezade Carrillo, Francisco Javier Sánchez-Vázquez, José Fernando López-Olmed. Combined blue light and daily thermocycles enhance zebrafish growth and development. Journal of experimental zoology. Part A, Ecological and integrative physiology. 2022-02-21. PMID:35189038. |
it analyzed the expression of the genes involved in stress (crh), somatic growth (gh, ifg1a, igf2a), and food intake control (npy, agrp, ghrelin, orexin, mch1, mch2, grp, cck8) at 10 and 30 dpf. |
2022-02-21 |
2023-08-13 |
zebrafish |
| Elisabeth K Goodman, Caitlin S Mitchell, Jonathan D Teo, Joanne M Gladding, Kirsten N Abbott, Neda Rafiei, Lei Zhang, Herbert Herzog, Denovan P Beg. The effect of insulin receptor deletion in neuropeptide Y neurons on hippocampal dependent cognitive function in aging mice. Journal of integrative neuroscience. vol 21. issue 1. 2022-02-15. PMID:35164442. |
insulin receptors are found in neuropeptide-y (npy) expressing neurons, which are abundant in the hypothalamus and hippocampus; regions involved in feeding behaviour and spatial memory, respectively. |
2022-02-15 |
2023-08-13 |
mouse |
| Chaehee Park, Jinuk Kim, Seung-Bum Ko, Yeol Kyo Choi, Hyeongseop Jeong, Hyeonuk Woo, Hyunook Kang, Injin Bang, Sang Ah Kim, Tae-Young Yoon, Chaok Seok, Wonpil Im, Hee-Jung Cho. Structural basis of neuropeptide Y signaling through Y1 receptor. Nature communications. vol 13. issue 1. 2022-02-15. PMID:35165283. |
neuropeptide y (npy) is highly abundant in the brain and involved in various physiological processes related to food intake and anxiety, as well as human diseases such as obesity and cancer. |
2022-02-15 |
2023-08-13 |
human |
| Yue Qi, Nicola J Lee, Chi Kin Ip, Ronaldo Enriquez, Ramon Tasan, Lei Zhang, Herbert Herzo. NPY derived from AGRP neurons controls feeding via Y1 and energy expenditure and food foraging behaviour via Y2 signalling. Molecular metabolism. 2022-02-15. PMID:35167990. |
npy derived from agrp neurons controls feeding via y1 and energy expenditure and food foraging behaviour via y2 signalling. |
2022-02-15 |
2023-08-13 |
Not clear |
| Yue Qi, Nicola J Lee, Chi Kin Ip, Ronaldo Enriquez, Ramon Tasan, Lei Zhang, Herbert Herzo. NPY derived from AGRP neurons controls feeding via Y1 and energy expenditure and food foraging behaviour via Y2 signalling. Molecular metabolism. 2022-02-15. PMID:35167990. |
here we aimed to determine what aspects of feeding behaviour and energy homeostasis is controlled by npy originating from agrp neurons and which y-receptor pathways are utilised to fulfill this function. |
2022-02-15 |
2023-08-13 |
Not clear |
| Philip J Medeiros, Sydney A Pascetta, Sarah M Kirsh, Baraa K Al-Khazraji, James Uniack. Expression of hypoxia inducible factor-dependent Neuropeptide Y Receptors Y1 and Y5 sensitizes hypoxic cells to NPY stimulation. The Journal of biological chemistry. 2022-01-30. PMID:35093384. |
neuropeptide y (npy) is an abundant neurohormone in the central and peripheral nervous system involved in feeding behavior, energy balance, nociception, and anxiety. |
2022-01-30 |
2023-08-13 |
Not clear |
| Pilar Marcos Rabal, Rafael Coveña. Regulation of homeostasis by neuropeptide Y: involvement in food intake. Current medicinal chemistry. 2021-12-28. PMID:34961454. |
the aim of this review is to update the physiological actions mediated by the orexigenic peptide npy, via its receptors, in the control of food intake and to review its involvement in food intake disorders. |
2021-12-28 |
2023-08-13 |
Not clear |
| Pilar Marcos Rabal, Rafael Coveña. Regulation of homeostasis by neuropeptide Y: involvement in food intake. Current medicinal chemistry. 2021-12-28. PMID:34961454. |
the relationships between npy and other substances involved in food intake mechanisms, hypothalamic and extra-hypothalamic pathways involved in feeding and the potential pharmacological strategies to treat obesity will be discussed. |
2021-12-28 |
2023-08-13 |
Not clear |
| Sahar Rajaei, Morteza Zendehdel, Mehdi Rahnema, Shahin Hassanpour, Masoumeh Asle-Roust. Mediatory role of the central NPY, melanocortine and corticotrophin systems on phoenixin-14 induced hyperphagia in neonatal chicken. General and comparative endocrinology. vol 315. 2021-12-06. PMID:34673032. |
animal research indicates the neuropeptide y (npy), corticotrophin and melanocortin systems have a mediatory role in reward, however, how these substances interact with phenytoin-14 (pnx-14) induced food intake in birds remains to be identified. |
2021-12-06 |
2023-08-13 |
chicken |
| Ying Liu, Yu-Chen Xu, Yu-Gui Cui, Shi-Wen Jiang, Fei-Yang Diao, Jia-Yin Liu, Xiang M. Androgen excess increases food intake in a rat polycystic ovary syndrome model by down-regulating hypothalamus insulin and leptin signaling pathways preceding weight gain. Neuroendocrinology. 2021-11-30. PMID:34847556. |
consistent with this, the expression of npy and agouti-related peptide (agrp) mrnas were up-regulated, which occurred prior to obesity and even with restricted food intake. |
2021-11-30 |
2023-08-13 |
rat |
| Boonyarit Kamkrathok, Natagarn Sartsoongnoen, Yupaporn Chaiseh. Neuropeptide Y and maternal behavior in the female native Thai chicken. Acta histochemica. vol 123. issue 4. 2021-11-29. PMID:33711725. |
neuropeptide y (npy), a neurotransmitter/neuromodulator, is very well known to be involved in food intake regulation in birds and mammals. |
2021-11-29 |
2023-08-13 |
chicken |
| Wanxiu Cao, Fang Liu, Robert W Li, Ruili Yang, Yuming Wang, Changhu Xue, Qingjuan Tan. Triacylglycerol rich in docosahexaenoic acid regulated appetite via the mediation of leptin and intestinal epithelial functions in high-fat, high-sugar diet-fed mice. The Journal of nutritional biochemistry. vol 99. 2021-11-26. PMID:34517098. |
dha-tg could reduce food intake and regulate neuropeptides (pomc, agrp, and npy) expression in hfhs diet-fed mice. |
2021-11-26 |
2023-08-13 |
mouse |
| Marimo Sato, Shiori Minabe, Takahiro Sakono, Fumie Magata, Sho Nakamura, Youki Watanabe, Naoko Inoue, Yoshihisa Uenoyama, Hiroko Tsukamura, Fuko Matsud. Morphological Analysis of the Hindbrain Glucose Sensor-Hypothalamic Neural Pathway Activated by Hindbrain Glucoprivation. Endocrinology. vol 162. issue 9. 2021-11-24. PMID:34161572. |
taken together, these results suggest that lowered glucose availability, sensed by 4v ependymal cells, activates hindbrain catecholaminergic and/or npy neurons followed by crh neurons in the pvn and npy neurons in the arc, thereby leading to counterregulatory responses, such as an enhancement of gluconeogenesis, increased food intake, and suppression of sex steroid secretion. |
2021-11-24 |
2023-08-13 |
rat |
| Emma K McIlwraith, Calvin V Lieu, Denise D Belsha. Bisphenol A induces miR-708-5p through an ER stress-mediated mechanism altering neuronatin and neuropeptide Y expression in hypothalamic neuronal models. Molecular and cellular endocrinology. vol 539. 2021-11-23. PMID:34624438. |
overexpression of an mir-708-5p mimic resulted in a reduction of neuronatin, a proteolipid whose loss of expression is associated with obesity, and an increase in orexigenic npy expression, thus potentially increasing feeding through converging regulatory pathways. |
2021-11-23 |
2023-08-13 |
Not clear |
| Andy Tran, Wenyuan He, Jim T C Chen, Leigh Wellhauser, Kathyrn E Hopperton, Richard P Bazinet, Denise D Belsha. Palmitate-mediated induction of neuropeptide Y expression occurs through intracellular metabolites and not direct exposure to proinflammatory cytokines. Journal of neurochemistry. vol 159. issue 3. 2021-11-19. PMID:34482548. |
these fats induce hypothalamic neuroinflammation, which dysregulates neuronal function and induces orexigenic neuropeptide y (npy) to promote food intake. |
2021-11-19 |
2023-08-13 |
Not clear |
| Matthew K H Wong, Yuan Chen, Mulan He, Chengyuan Lin, Zhaoxiang Bian, Anderson O L Won. Mouse Spexin: (II) Functional Role as a Satiety Factor inhibiting Food Intake by Regulatory Actions Within the Hypothalamus. Frontiers in endocrinology. vol 12. 2021-11-18. PMID:34276562. |
furthermore, ip injection of spx was effective in reducing food intake with parallel attenuation in transcript expression of npy, agrp, npy type 5 receptor (npy5r), and ghrelin receptor (ghsr) in the hypothalamus, and these inhibitory effects could be blocked by galr3 but not galr2 antagonism. |
2021-11-18 |
2023-08-13 |
mouse |
| Matthew K H Wong, Yuan Chen, Mulan He, Chengyuan Lin, Zhaoxiang Bian, Anderson O L Won. Mouse Spexin: (II) Functional Role as a Satiety Factor inhibiting Food Intake by Regulatory Actions Within the Hypothalamus. Frontiers in endocrinology. vol 12. 2021-11-18. PMID:34276562. |
through galr3 activation, this spx signal can act within the hypothalamus to trigger feedback inhibition on feeding by differential modulation of feeding regulators (npy and agrp) and their receptors (npy5r, ghsr, lepr, and mc4r) involved in the feeding circuitry within the cns. |
2021-11-18 |
2023-08-13 |
mouse |
| Joana Duarte-Neves, Cláudia Cavadas, Luís Pereira de Almeid. Neuropeptide Y (NPY) intranasal delivery alleviates Machado-Joseph disease. Scientific reports. vol 11. issue 1. 2021-11-11. PMID:33558582. |
furthermore, intranasal administration of npy did not alter body weight gain, food intake, amount of body fat nor cholesterol or triglycerides levels. |
2021-11-11 |
2023-08-13 |
mouse |