Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Dengyue Yuan, Yundi Gao, Xin Zhang, Bin Wang, Hu Chen, Yuanbing Wu, Defang Chen, Zhijian Wang, Zhiqiong L. NPY and NPY receptors in the central control of feeding and interactions with CART and MC4R in Siberian sturgeon. General and comparative endocrinology. vol 284. 2020-02-25. PMID:31394086. |
neuropeptide y (npy) is the most powerful central neuropeptide implicated in feeding regulation via its receptors. |
2020-02-25 |
2023-08-13 |
Not clear |
Dengyue Yuan, Yundi Gao, Xin Zhang, Bin Wang, Hu Chen, Yuanbing Wu, Defang Chen, Zhijian Wang, Zhiqiong L. NPY and NPY receptors in the central control of feeding and interactions with CART and MC4R in Siberian sturgeon. General and comparative endocrinology. vol 284. 2020-02-25. PMID:31394086. |
understanding the role of npy system is critical to elucidate animal feeding regulation. |
2020-02-25 |
2023-08-13 |
Not clear |
Dengyue Yuan, Yundi Gao, Xin Zhang, Bin Wang, Hu Chen, Yuanbing Wu, Defang Chen, Zhijian Wang, Zhiqiong L. NPY and NPY receptors in the central control of feeding and interactions with CART and MC4R in Siberian sturgeon. General and comparative endocrinology. vol 284. 2020-02-25. PMID:31394086. |
unlike mammal, the possible mechanisms of npy system in the food intake of teleost fish are mostly unknown. |
2020-02-25 |
2023-08-13 |
Not clear |
Dengyue Yuan, Yundi Gao, Xin Zhang, Bin Wang, Hu Chen, Yuanbing Wu, Defang Chen, Zhijian Wang, Zhiqiong L. NPY and NPY receptors in the central control of feeding and interactions with CART and MC4R in Siberian sturgeon. General and comparative endocrinology. vol 284. 2020-02-25. PMID:31394086. |
the expression of npy was decreased in the brain after feeding 1 and 3 h. |
2020-02-25 |
2023-08-13 |
Not clear |
Liyuan Lv, Xu-Fang Liang, Kang Huang, Shan H. Effect of agmatine on food intake in mandarin fish (Siniperca chuatsi). Fish physiology and biochemistry. vol 45. issue 5. 2020-02-18. PMID:31140073. |
furthermore, the food intake in agmatine treatment mostly did not differ from that in saline treatment at 4--24-h post-injection as well as the results of genes expression of neuropeptide y (npy), agouti-regulated peptide (agrp), and anorexigenic melanocortin 4 receptor (mc4r). |
2020-02-18 |
2023-08-13 |
Not clear |
Nazli Khajehnasiri, Homayoun Khazali, Farzam Sheikhzadeh, Mahnaz Ghows. One-month of high-intensity exercise did not change the food intake and the hypothalamic arcuate nucleus proopiomelanocortin and neuropeptide Y expression levels in male Wistar rats. Endocrine regulations. vol 53. issue 1. 2020-02-12. PMID:31517616. |
the aim of this study was to investigate the effects of one-month lasting high-intensity exercise on the pomc mrna and npy mrna expression in the above-mentioned brain structure and appetite and food intake levels. |
2020-02-12 |
2023-08-13 |
rat |
Xiaojiao Xu, Xiaoling Chen, Zhiqing Huang, Daiwen Chen, Bing Yu, Hong Chen, Ping Zheng, Yuheng Luo, Jie Y. An effect of dietary phloretin supplementation on feed intake in mice. Food & function. vol 10. issue 9. 2020-02-11. PMID:31453624. |
our present study provides evidence that dietary phloretin supplementation could increase feed intake in mice, which might be attributed to the stimulation of the hypothalamic feeding center via ghrelin, mirnas (mir-103 and mir-488) and feeding signal factor-related genes (npy, agrp, mc4r and pomc), and to the inhibition of cck to increase gastric emptying. |
2020-02-11 |
2023-08-13 |
mouse |
Ranakul Islam, Christine M Prater, Breanna N Harris, James A Car. Neuroendocrine modulation of predator avoidance/prey capture tradeoffs: Role of tectal NPY2R receptors. General and comparative endocrinology. vol 282. 2020-01-21. PMID:31271760. |
we tested two questions: 1) does tectal npy administration decrease food intake and alter prey-capture behavior? |
2020-01-21 |
2023-08-13 |
xenopus_laevis |
Ranakul Islam, Christine M Prater, Breanna N Harris, James A Car. Neuroendocrine modulation of predator avoidance/prey capture tradeoffs: Role of tectal NPY2R receptors. General and comparative endocrinology. vol 282. 2020-01-21. PMID:31271760. |
npy microinjected bilaterally into the tecta failed to significantly alter food intake at any dose tested, although predator presence significantly reduced food intake. |
2020-01-21 |
2023-08-13 |
xenopus_laevis |
Sydney London, Helene Volkof. Cloning and effects of fasting on the brain expression levels of appetite-regulators and reproductive hormones in glass catfish (Kryptopterus vitreolus). Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 228. 2019-12-31. PMID:30453036. |
orexin and neuropeptide y - npy) or anorexigenic (inhibit food intake, e.g. |
2019-12-31 |
2023-08-13 |
Not clear |
Nathaneal J Huston, Lynne A Brenner, Zachary C Taylor, Robert C Ritte. NPY2 receptor activation in the dorsal vagal complex increases food intake and attenuates CCK-induced satiation in male rats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 316. issue 4. 2019-12-30. PMID:30726118. |
intracerebroventricular injections of npy or pyy increase food intake, and intrahypothalamic npy1 or npy5 receptor agonist injections also increase food intake. |
2019-12-30 |
2023-08-13 |
rat |
Giulia Baldini, Kevin D Phela. The melanocortin pathway and control of appetite-progress and therapeutic implications. The Journal of endocrinology. vol 241. issue 1. 2019-12-16. PMID:30812013. |
conversely, in the 'starved state' activity of agouti-related neuropeptide (agrp) and of neuropeptide y (npy)-expressing neurons is increased by decreased levels of circulating leptin and insulin and by the orexigenic hormone ghrelin to promote food intake. |
2019-12-16 |
2023-08-13 |
mouse |
Chayon Goswami, Katsuya Dezaki, Lei Wang, Akio Inui, Yutaka Seino, Toshihiko Yad. Ninjin-yoeito activates ghrelin-responsive and unresponsive NPY neurons in the arcuate nucleus and counteracts cisplatin-induced anorexia. Neuropeptides. vol 75. 2019-12-16. PMID:30948035. |
this study sought to determine whether ninjin-yoeito influences npy and/or ghrelin-responsive neurons in the hypothalamic arcuate nucleus (arc), a feeding center. |
2019-12-16 |
2023-08-13 |
mouse |
Lei Zhang, Diana Hernandez-Sanchez, Herbert Herzo. Regulation of Feeding-Related Behaviors by Arcuate Neuropeptide Y Neurons. Endocrinology. vol 160. issue 6. 2019-12-06. PMID:31089694. |
however, genetic mouse models in combination with novel neuron-controlling chemogenetic and optogenetic technologies have also uncovered additional functions for this arc npy population that go beyond the simple food intake stimulatory action and link these npy neurons to the control of energy expenditure, thermogenesis, physical activity, food-seeking behavior, and anxiety. |
2019-12-06 |
2023-08-13 |
mouse |
Tianming Wang, Jing Liang, Xiaowei Xiang, Xu Chen, Bing Zhang, Naiming Zhou, Wei Huang, Jingwen Yan. Pharmacological characterization, cellular localization and expression profile of NPY receptor subtypes Y2 and Y7 in large yellow croaker, Larimichthys crocea. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. vol 238. 2019-11-25. PMID:31499219. |
neuropeptide y (npy) receptors are suggested to mediate the multi-physiological functions of npy family peptides, such as food intake, in teleost fish. |
2019-11-25 |
2023-08-13 |
Not clear |
Akana, Hanson, Horsley, Strack, Bhatnagar, Bradbury, Milligan, Dallma. Clamped Corticosterone (B) Reveals the Effect of Endogenous B on Both Facilitated Responsivity to Acute Restraint and Metabolic Responses to Chronic Stress. Stress (Amsterdam, Netherlands). vol 1. issue 1. 2019-11-20. PMID:9807060. |
npy does not induce facilitation of afferent stress pathways; 3. chronic stimulation of the hpa axis induces acute hyperresponsiveness of hypothalamic neurons to restraint provided that the afferent input of this acute stimulus is not prevented by b feedback; 4. stimulus-induced elevations in b secretion result in day-time feeding; 5. insensitivity of both caloric efficiency and white fat stores to chronic stress in adrenalectomized, b-clamped rats results from loss of normally variable b levels. |
2019-11-20 |
2023-08-12 |
rat |
Seetharama D S Jois, Latha M Nagarajarao, M Prabhakaran, A Balasubramania. Modeling of Neuropeptide Receptors Y1, Y4, Y5, and Docking Studies with Neuropeptide Antagonist Analogues: Implications for Selectivity. Journal of biomolecular structure & dynamics. vol 22. issue 1. 2019-11-20. PMID:22640480. |
npy mediates several physiological responses, such as blood pressure, food intake, sedation. |
2019-11-20 |
2023-08-12 |
Not clear |
Antonio Moreno-Herrera, Abraham García, Isidro Palos, Gildardo River. Neuropeptide Y1 and Y5 Receptor Antagonists as Potential Anti-Obesity Drugs. Current Status. Mini reviews in medicinal chemistry. 2019-11-20. PMID:25355591. |
at the beginning of this century, npy receptor antagonists were considered promising anti-obesity compounds that modulate food intake and body weight in obese patients; however, only a few antagonists are currently being evaluated in clinical trials because there are other neuronal pathways that maintain homeostasis of food intake and body weight in animals, making the design of molecules with more affinity and selectivity for the npy y1 and y5 receptors necessary. |
2019-11-20 |
2023-08-13 |
mouse |
Kim Loh, Lei Zhang, Amanda Brandon, Qiaoping Wang, Denovan Begg, Yue Qi, Melissa Fu, Rishikesh Kulkarni, Jonathan Teo, Paul Baldock, Jens C Bruning, Gregory Cooney, Greg G Neely, Herbert Herzo. Corrigendum to "Insulin controls food intake and energy balance via NPY neurons" [Mol Metabol 6 (2017) 574-584]. Molecular metabolism. vol 6. issue 11. 2019-11-20. PMID:29107301. |
corrigendum to "insulin controls food intake and energy balance via npy neurons" [mol metabol 6 (2017) 574-584]. |
2019-11-20 |
2023-08-13 |
Not clear |
Ilvana Ziko, Luba Sominsky, Thai-Xinh Nguyen, Kit-Yi Yam, Simone De Luca, Aniko Korosi, Sarah J Spence. Hyperleptinemia in Neonatally Overfed Female Rats Does Not Dysregulate Feeding Circuitry. Frontiers in endocrinology. vol 8. 2019-11-20. PMID:29123503. |
these effects are associated with a short-term disruption in the connectivity of neuropeptide y (npy), agouti-related peptide (agrp), and pro-opiomelanocortin (pomc) neurons within the regions of the hypothalamus responsible for control of energy balance and food intake. |
2019-11-20 |
2023-08-13 |
rat |