| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yumiko Fukasaka, Hirohide Nambu, Hideki Tanioka, Atsushi Obata, Misato Tonomura, Takayuki Okuno, Hideo Yukiok. An insurmountable NPY Y5 receptor antagonist exhibits superior anti-obesity effects in high-fat diet-induced obese mice. Neuropeptides. vol 70. 2018-10-25. PMID:29801968. |
neuropeptide y (npy) y5 receptor plays a key role in the effects of npy, an important neurotransmitter in the control of energy homeostasis including stimulation of food intake and inhibition of energy expenditure. |
2018-10-25 |
2023-08-13 |
mouse |
| Qiang Wei, David M Krolewski, Shannon Moore, Vivek Kumar, Fei Li, Brian Martin, Raju Tomer, Geoffrey G Murphy, Karl Deisseroth, Stanley J Watson, Huda Aki. Uneven balance of power between hypothalamic peptidergic neurons in the control of feeding. Proceedings of the National Academy of Sciences of the United States of America. vol 115. issue 40. 2018-10-17. PMID:30224492. |
two classes of peptide-producing neurons in the arcuate nucleus (arc) of the hypothalamus are known to exert opposing actions on feeding: the anorexigenic neurons that express proopiomelanocortin (pomc) and the orexigenic neurons that express agouti-related protein (agrp) and neuropeptide y (npy). |
2018-10-17 |
2023-08-13 |
Not clear |
| Cristina Velasco, Guillermo Moreiras, Marta Conde-Sieira, José M Leao, Jesús M Míguez, José L Soenga. Ceramide counteracts the effects of ghrelin on the metabolic control of food intake in rainbow trout. The Journal of experimental biology. vol 220. issue Pt 14. 2018-10-10. PMID:28495865. |
the presence of ceramide generally counteracted the effects elicited by ghrl on fatty acid-sensing systems, the capacity of integrative sensors (ampk, mtor and sirt-1), proteins involved in cellular signalling pathways (akt and foxo1) and neuropeptides involved in the regulation of food intake (agrp, npy, pomc and cart). |
2018-10-10 |
2023-08-13 |
Not clear |
| Betty R McConn, Elizabeth R Gilbert, Mark A Clin. Appetite-associated responses to central neuropeptide Y injection in quail. Neuropeptides. vol 69. 2018-09-28. PMID:29573813. |
the aim of this study was to determine the effects of central injection of npy on feeding behavior and hypothalamic physiology in 7 day-old japanese quail (coturnix japonica). |
2018-09-28 |
2023-08-13 |
Not clear |
| Betty R McConn, Elizabeth R Gilbert, Mark A Clin. Appetite-associated responses to central neuropeptide Y injection in quail. Neuropeptides. vol 69. 2018-09-28. PMID:29573813. |
during the light cycle, intracerebroventricular injection of 1.9 pmol, 0.5, and 1.0 nmol doses of npy did not affect food intake, 0.031 to 0.13 nmol increased food intake, and 2.0 nmol npy decreased food intake, in comparison to vehicle injection. |
2018-09-28 |
2023-08-13 |
Not clear |
| Betty R McConn, Elizabeth R Gilbert, Mark A Clin. Appetite-associated responses to central neuropeptide Y injection in quail. Neuropeptides. vol 69. 2018-09-28. PMID:29573813. |
when injected during the dark cycle, npy did not influence food intake. |
2018-09-28 |
2023-08-13 |
Not clear |
| Betty R McConn, Elizabeth R Gilbert, Mark A Clin. Appetite-associated responses to central neuropeptide Y injection in quail. Neuropeptides. vol 69. 2018-09-28. PMID:29573813. |
lastly, quail injected with npy increased feeding pecks, escape attempts, and time spent preening, while locomotion, the number of steps, and time spent perching decreased compared to chicks injected with the vehicle. |
2018-09-28 |
2023-08-13 |
Not clear |
| Betty R McConn, Elizabeth R Gilbert, Mark A Clin. Appetite-associated responses to central neuropeptide Y injection in quail. Neuropeptides. vol 69. 2018-09-28. PMID:29573813. |
results demonstrate that npy stimulates food intake in quail, consistent with mammals and other avian species, but with some unique responses at the molecular level that are not documented in other species. |
2018-09-28 |
2023-08-13 |
Not clear |
| Zhenlin Yang, Shuo Han, Max Keller, Anette Kaiser, Brian J Bender, Mathias Bosse, Kerstin Burkert, Lisa M Kögler, David Wifling, Guenther Bernhardt, Nicole Plank, Timo Littmann, Peter Schmidt, Cuiying Yi, Beibei Li, Sheng Ye, Rongguang Zhang, Bo Xu, Dan Larhammar, Raymond C Stevens, Daniel Huster, Jens Meiler, Qiang Zhao, Annette G Beck-Sickinger, Armin Buschauer, Beili W. Structural basis of ligand binding modes at the neuropeptide Y Y Nature. vol 556. issue 7702. 2018-08-27. PMID:29670288. |
structural basis of ligand binding modes at the neuropeptide y y neuropeptide y (npy) receptors belong to the g-protein-coupled receptor superfamily and have important roles in food intake, anxiety and cancer biology |
2018-08-27 |
2023-08-13 |
Not clear |
| Jin-Hyoung Kim, Satid Chatchaiphan, Michelle T Crown, Samantha L White, Robert H Devli. Effect of growth hormone overexpression on gastric evacuation rate in coho salmon. Fish physiology and biochemistry. vol 44. issue 1. 2018-08-17. PMID:28894993. |
mch and npy showed significantly lower mrna levels than nt fish in all brain tissues examined across all time-points after feeding. |
2018-08-17 |
2023-08-13 |
Not clear |
| Yu-Hui He, Ling Li, Xu-Fang Liang, Shan He, Luo Zhao, Yan-Peng Zhan. Inhibitory neurotransmitter serotonin and excitatory neurotransmitter dopamine both decrease food intake in Chinese perch (Siniperca chuatsi). Fish physiology and biochemistry. vol 44. issue 1. 2018-08-17. PMID:28929258. |
in the present study, the effects of serotonin (5-ht) and dopamine (da) on food intake were evaluated through intraventricular (icv) administration in chinese perch (siniperca chuatsi) and the mrna expression levels of neuropeptide y (npy), agouti gene-related protein (agrp), and pro-opiomelanocortin (pomc) were detected. |
2018-08-17 |
2023-08-13 |
Not clear |
| Yu-Hui He, Ling Li, Xu-Fang Liang, Shan He, Luo Zhao, Yan-Peng Zhan. Inhibitory neurotransmitter serotonin and excitatory neurotransmitter dopamine both decrease food intake in Chinese perch (Siniperca chuatsi). Fish physiology and biochemistry. vol 44. issue 1. 2018-08-17. PMID:28929258. |
the mrna expression of npy and agrp were significantly decreased (p < 0.05), whereas the mrna expression of pomc was significantly increased (p < 0.05), suggesting the involvement of npy, agrp, and pomc in inhibitory action of 5-ht on food intake in chinese perch. |
2018-08-17 |
2023-08-13 |
Not clear |
| Raul Cortés, Mariana Teles, Miguel Oliveira, Camino Fierro-Castro, Lluis Tort, José Miguel Cerdá-Reverte. Effects of acute handling stress on short-term central expression of orexigenic/anorexigenic genes in zebrafish. Fish physiology and biochemistry. vol 44. issue 1. 2018-08-17. PMID:29071448. |
all three orexigenic peptides examined, i.e., neuropeptide y (npy), agouti-related protein (agrp), and ghrelin, increased their central expression level suggesting that these neuronal systems are not involved in the short-term feeding inhibitory effects of acute stress. |
2018-08-17 |
2023-08-13 |
zebrafish |
| Michio Komai, Tomoko Goto, Kousaku Ohinata, Taiho Kambe, Yuki Mayanagi, Hitoshi Shirakaw. [Clarification of the Mechanism Involved in Orexigenic Action by Oral Zinc Ingestion]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 138. issue 8. 2018-08-16. PMID:30068840. |
the mrna expressions of hypothalamic peptides, such as orexin (ox) and neuropeptide y (npy), were increased after oral administration of zinc to increase food intake. |
2018-08-16 |
2023-08-13 |
rat |
| Lucia Recinella, Sheila Leone, Claudio Ferrante, Annalisa Chiavaroli, Rugia Shohreh, Chiara Di Nisio, Michele Vacca, Giustino Orlando, Roberto Salvatori, Luigi Brunett. Effects of growth hormone-releasing hormone gene targeted ablation on ghrelin-induced feeding. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. vol 37. 2018-07-23. PMID:29121520. |
in conclusion, dysregulation of the ghrelin-ghrh-gh axis in ghrhko mice could lead to increased feeding secondary to elevated circulating levels of ghrelin, and the obesogenic phenotype is likely mediated by elevated npy and agrp, and decreased crh gene expression in the hypothalamus. |
2018-07-23 |
2023-08-13 |
mouse |
| Yanyan Wei, Jiangbo Li, Huiling Wang, Gaohua Wan. NUCB2/nesfatin-1: Expression and functions in the regulation of emotion and stress. Progress in neuro-psychopharmacology & biological psychiatry. vol 81. 2018-07-03. PMID:28963067. |
some anorexigenic or orexigenic neurotransmitters also play a role in the adjustment of emotion and stress responses in addition to their actions on the homeostatic regulation of food intake, including neuropeptide y (npy), melanocyte stimulating hormone (msh), corticotropin-releasing factor (crf), and ghrelin. |
2018-07-03 |
2023-08-13 |
Not clear |
| Ashley R Lucas, Daelyn Y Richards, Lucy M Ramirez, Deborah I Lutterschmid. Arginine Vasotocin and Neuropeptide Y Vary with Seasonal Life-History Transitions in Garter Snakes. Integrative and comparative biology. vol 57. issue 6. 2018-06-28. PMID:28992226. |
while the neuroendocrine mechanisms that regulate such behavioral transitions are poorly understood, arginine vasotocin (avt) and neuropeptide y (npy) are excellent candidates because they modulate reproductive and feeding behavior, respectively. |
2018-06-28 |
2023-08-13 |
Not clear |
| Ashley R Lucas, Daelyn Y Richards, Lucy M Ramirez, Deborah I Lutterschmid. Arginine Vasotocin and Neuropeptide Y Vary with Seasonal Life-History Transitions in Garter Snakes. Integrative and comparative biology. vol 57. issue 6. 2018-06-28. PMID:28992226. |
we asked if seasonal changes in avt and npy are concomitant with the seasonal migration to and from the feeding grounds in red-sided garter snakes (thamnophis sirtalis parietalis). |
2018-06-28 |
2023-08-13 |
Not clear |
| Priscila Vázquez-León, Luis G Mendoza-Ruiz, Eduardo Ramírez-San Juan, German Alberto Chamorro-Cevallos, Abraham Miranda-Páe. Analgesic and anxiolytic effects of [Leu Neuropeptides. vol 66. 2018-06-27. PMID:29042065. |
analgesic and anxiolytic effects of [leu several reports have demonstrated that neuropeptide y (npy) is involved in food intake, epilepsy, circadian rhythms, drug seeking, pain and anxiety, and other physiological or pathological conditions. |
2018-06-27 |
2023-08-13 |
Not clear |
| Shigetomo Suyama, Wang Lei, Naoto Kubota, Takashi Kadowaki, Toshihiko Yad. Adiponectin at physiological level glucose-independently enhances inhibitory postsynaptic current onto NPY neurons in the hypothalamic arcuate nucleus. Neuropeptides. vol 65. 2018-06-14. PMID:28606559. |
the arc contains orexigenic neuropeptide y (npy)/agouti related peptide (agrp) neurons and anorexigenic proopiomelanocortin (pomc) neurons, the first order neurons for feeding regulation. |
2018-06-14 |
2023-08-13 |
Not clear |