| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P D Raposinho, D D Pierroz, P Broqua, R B White, T Pedrazzini, M L Auber. Chronic administration of neuropeptide Y into the lateral ventricle of C57BL/6J male mice produces an obesity syndrome including hyperphagia, hyperleptinemia, insulin resistance, and hypogonadism. Molecular and cellular endocrinology. vol 185. issue 1-2. 2003-03-28. PMID:11738809. |
gene expression for hypothalamic pomc was reduced in the npy- or pyy(3-36)-infused mice, suggesting that npy exacerbated food intake by both acting through its own receptor(s), and reducing the satiety signal driven by the pomc-derived alpha-msh. |
2003-03-28 |
2023-08-12 |
mouse |
| P D Raposinho, D D Pierroz, P Broqua, R B White, T Pedrazzini, M L Auber. Chronic administration of neuropeptide Y into the lateral ventricle of C57BL/6J male mice produces an obesity syndrome including hyperphagia, hyperleptinemia, insulin resistance, and hypogonadism. Molecular and cellular endocrinology. vol 185. issue 1-2. 2003-03-28. PMID:11738809. |
the present study in the mouse suggests in analogy with available rat data, that constant exposure to elevated npy in the hypothalamic area unabatedly enhances food intake leading to an obesity syndrome including increased adiposity, insulin resistance, hypercorticism, and hypogonadism, reminiscent of the phenotype of the ob/ob mouse, that displays elevated hypothalamic npy secondary to lack of leptin negative feedback action. |
2003-03-28 |
2023-08-12 |
mouse |
| Tetsuya Tachibana, Tomo Takagi, Shozo Tomonaga, Atsushi Ohgushi, Ryuichi Ando, D Michael Denbow, Mitsuhiro Furus. Central administration of cocaine- and amphetamine-regulated transcript inhibits food intake in chicks. Neuroscience letters. vol 337. issue 3. 2003-03-28. PMID:12536041. |
in addition, the icv injection of cart attenuated neuropeptide y (npy)-induced feeding in both broiler and layer chicks. |
2003-03-28 |
2023-08-12 |
Not clear |
| Tetsuya Tachibana, Tomo Takagi, Shozo Tomonaga, Atsushi Ohgushi, Ryuichi Ando, D Michael Denbow, Mitsuhiro Furus. Central administration of cocaine- and amphetamine-regulated transcript inhibits food intake in chicks. Neuroscience letters. vol 337. issue 3. 2003-03-28. PMID:12536041. |
furthermore, the present study also demonstrates that cart interacts with npy in the central nervous system to regulate feeding in chicks. |
2003-03-28 |
2023-08-12 |
Not clear |
| P D Raposinho, R B White, M L Auber. The melanocortin agonist Melanotan-II reduces the orexigenic and adipogenic effects of neuropeptide Y (NPY) but does not affect the NPY-driven suppressive effects on the gonadotropic and somatotropic axes in the male rat. Journal of neuroendocrinology. vol 15. issue 2. 2003-03-26. PMID:12535159. |
when given as an intracerebroventricular bolus injection, melanotan-ii (mt-ii), a non selective mc receptor agonist, inhibits feeding, suppresses the npy orexigenic action, and reduces basal insulinaemia. |
2003-03-26 |
2023-08-12 |
rat |
| P D Raposinho, R B White, M L Auber. The melanocortin agonist Melanotan-II reduces the orexigenic and adipogenic effects of neuropeptide Y (NPY) but does not affect the NPY-driven suppressive effects on the gonadotropic and somatotropic axes in the male rat. Journal of neuroendocrinology. vol 15. issue 2. 2003-03-26. PMID:12535159. |
when coinfused with npy, mt-ii also produced the same initial anorectic episode but then maintained feeding to upper normal levels, thus cancelling the hyperphagia driven by npy. |
2003-03-26 |
2023-08-12 |
rat |
| P D Raposinho, R B White, M L Auber. The melanocortin agonist Melanotan-II reduces the orexigenic and adipogenic effects of neuropeptide Y (NPY) but does not affect the NPY-driven suppressive effects on the gonadotropic and somatotropic axes in the male rat. Journal of neuroendocrinology. vol 15. issue 2. 2003-03-26. PMID:12535159. |
when coinfused with npy, mt-ii was able to cancel most of the npy effects on feeding, but not those on the neuroendocrine axes. |
2003-03-26 |
2023-08-12 |
rat |
| P D Raposinho, R B White, M L Auber. The melanocortin agonist Melanotan-II reduces the orexigenic and adipogenic effects of neuropeptide Y (NPY) but does not affect the NPY-driven suppressive effects on the gonadotropic and somatotropic axes in the male rat. Journal of neuroendocrinology. vol 15. issue 2. 2003-03-26. PMID:12535159. |
it appears therefore that, as expected, npy and alpha-msh closely interact in the control of feeding, whereas the neural pathways by which npy affects growth and reproduction are distinct and not sensitive to mc peptide modulation. |
2003-03-26 |
2023-08-12 |
rat |
| V Compère, S Li, J Leprince, M C Tonon, H Vaudry, G Pelletie. Effect of intracerebroventricular administration of the octadecaneuropeptide on the expression of pro-opiomelanocortin, neuropeptide Y and corticotropin-releasing hormone mRNAs in rat hypothalamus. Journal of neuroendocrinology. vol 15. issue 2. 2003-03-26. PMID:12535162. |
we studied the effect of odn on three neuropeptides involved in feeding behaviour: the orexigenic peptide neuropeptide y (npy) and two anorexigenic peptides, corticotropin-releasing hormone (crh) and the pro-opiomelanocortin (pomc)-derived peptide alpha-melanocyte-stimulating hormone. |
2003-03-26 |
2023-08-12 |
rat |
| Ambikaipakan Balasubramaniam, Sulaiman Sheriff, Weixu Zhai, William T Chanc. Bis(31/31')[[Cys(31), Nva(34)]NPY(27-36)-NH(2)]: a neuropeptide Y (NPY) Y(5) receptor selective agonist with a latent stimulatory effect on food intake in rats. Peptides. vol 23. issue 8. 2003-03-25. PMID:12182951. |
bis(31/31')[[cys(31), nva(34)]npy(27-36)-nh(2)]: a neuropeptide y (npy) y(5) receptor selective agonist with a latent stimulatory effect on food intake in rats. |
2003-03-25 |
2023-08-12 |
mouse |
| Ambikaipakan Balasubramaniam, Sulaiman Sheriff, Weixu Zhai, William T Chanc. Bis(31/31')[[Cys(31), Nva(34)]NPY(27-36)-NH(2)]: a neuropeptide Y (NPY) Y(5) receptor selective agonist with a latent stimulatory effect on food intake in rats. Peptides. vol 23. issue 8. 2003-03-25. PMID:12182951. |
investigations using receptor selective ligands and receptor knock-out mice suggest that npy effects on feeding are mediated by both y(1) and y(5) receptors. |
2003-03-25 |
2023-08-12 |
mouse |
| Rebecca E Campbell, M Susan Smith, Summer E Allen, Bernadette E Grayson, Jarlath M H Ffrench-Mullen, Kevin L Grov. Orexin neurons express a functional pancreatic polypeptide Y4 receptor. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 4. 2003-03-24. PMID:12598637. |
the receptor subtypes that mediate the effects of neuropeptide y (npy) on food intake have not been clearly defined. |
2003-03-24 |
2023-08-12 |
rat |
| Rebecca E Campbell, M Susan Smith, Summer E Allen, Bernadette E Grayson, Jarlath M H Ffrench-Mullen, Kevin L Grov. Orexin neurons express a functional pancreatic polypeptide Y4 receptor. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 4. 2003-03-24. PMID:12598637. |
both rpp and npy significantly increased food and water intake when they were administered into the lha, although npy was a more potent stimulator of food intake. |
2003-03-24 |
2023-08-12 |
rat |
| Philippe Naveilhan, Lennart Svensson, Susanne Nyström, A Jonas Ekstrand, Patrik Ernfor. Attenuation of hypercholesterolemia and hyperglycemia in ob/ob mice by NPY Y2 receptor ablation. Peptides. vol 23. issue 6. 2003-03-04. PMID:12126735. |
neuropeptide y (npy) is a 36 amino acid peptide well known for its role in regulating food intake and energy homeostasis. |
2003-03-04 |
2023-08-12 |
mouse |
| N D Cameron, E McCullough, K Troup, J C Penma. Serum neuropeptide Y (NPY) and leptin concentrations in pigs selected for components of efficient lean growth. Domestic animal endocrinology. vol 24. issue 1. 2003-03-03. PMID:12450622. |
at 90 kg liveweight, log transformed serum npy concentrations were increased with divergent selection for low food conversion ratio (lfc) (6.31 versus 5.72, sed 0.09 log(pmol/l)) or for high lean growth rate (lga) (5.80 versus 5.37 log(pmol/l)) but not with selection on daily food intake (dfi) (6.26 versus 6.14 log(pmol/l)). |
2003-03-03 |
2023-08-12 |
human |
| Christopher Bishop, Graham C Parker, Donald V Coscin. Nicotine and its withdrawal alter feeding induced by paraventricular hypothalamic injections of neuropeptide Y in Sprague-Dawley rats. Psychopharmacology. vol 162. issue 3. 2003-02-26. PMID:12122484. |
infusions of npy into the paraventricular nucleus of the hypothalamus (pvn), which normally produce robust feeding, were used to investigate changes in the pvn-npy system that may contribute to nic's effects on energy balance. |
2003-02-26 |
2023-08-12 |
rat |
| G Saracíbar, A Casado, V M Rodríguez, M P Portillo, M T Macarulla, L C Abecia, Enrique Echevarría, L Casi. Nefazodone alters NPY immunostaining in rat arcuate-paraventricular projection without changes in food intake and body weight. Nutritional neuroscience. vol 5. issue 5. 2003-02-12. PMID:12385598. |
nefazodone alters npy immunostaining in rat arcuate-paraventricular projection without changes in food intake and body weight. |
2003-02-12 |
2023-08-12 |
rat |
| G Saracíbar, A Casado, V M Rodríguez, M P Portillo, M T Macarulla, L C Abecia, Enrique Echevarría, L Casi. Nefazodone alters NPY immunostaining in rat arcuate-paraventricular projection without changes in food intake and body weight. Nutritional neuroscience. vol 5. issue 5. 2003-02-12. PMID:12385598. |
the aim of the present work was to study the effects of nefazodone on food intake, body weight, adiposity and hypothalamic npy immunostaining in rats. |
2003-02-12 |
2023-08-12 |
rat |
| G Saracíbar, A Casado, V M Rodríguez, M P Portillo, M T Macarulla, L C Abecia, Enrique Echevarría, L Casi. Nefazodone alters NPY immunostaining in rat arcuate-paraventricular projection without changes in food intake and body weight. Nutritional neuroscience. vol 5. issue 5. 2003-02-12. PMID:12385598. |
because nefazodone is an alpha1-adrenoceptor antagonist, it can be proposed that the expected decrease in food intake after nefazodone administration, due to its effects on npy arcuate-paraventricular projection, could be masked by the opposite orexigenic effect of alpha1-adrenoceptor blockade. |
2003-02-12 |
2023-08-12 |
rat |
| Dong-Yih Ku. Co-administration of dopamine D1 and D2 agonists additively decreases daily food intake, body weight and hypothalamic neuropeptide Y level in rats. Journal of biomedical science. vol 9. issue 2. 2003-01-24. PMID:11914579. |
this study investigated whether co-administration of dopamine d1 and d2 agonists might additively inhibit the feeding effect and whether this effect was mediated by the action on hypothalamic neuropeptide y (npy). |
2003-01-24 |
2023-08-12 |
rat |