| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Lüttgen, S O Ogren, B Meiste. 5-HT1A receptor mRNA and immunoreactivity in the rat medial septum/diagonal band of Broca-relationships to GABAergic and cholinergic neurons. Journal of chemical neuroanatomy. vol 29. issue 2. 2005-05-03. PMID:15652697. |
these observations suggest that serotonin via 5-ht1a receptors may represent an important modulator of hippocampal transmission important for cognitive and emotional functions through actions on both gabaergic and cholinergic neurons of the rat septal complex. |
2005-05-03 |
2023-08-12 |
rat |
| Martin E Keck, Simone B Sartori, Tobias Welt, Marianne B Müller, Frauke Ohl, Florian Holsboer, Rainer Landgraf, Nicolas Singewal. Differences in serotonergic neurotransmission between rats displaying high or low anxiety/depression-like behaviour: effects of chronic paroxetine treatment. Journal of neurochemistry. vol 92. issue 5. 2005-04-28. PMID:15715667. |
exposure to emotional stress failed to increase intrahippocampal 5-ht release in hab rats whereas lab rats displayed a physiological, albeit small rise. |
2005-04-28 |
2023-08-12 |
rat |
| Seppo Kähkönen, Ville Mäkinen, Iiro P Jääskeläinen, Sirpa Pennanen, Jyrki Liesivuori, Jyrki Ahvenine. Serotonergic modulation of mismatch negativity. Psychiatry research. vol 138. issue 1. 2005-04-26. PMID:15708302. |
here, we utilized acute tryptophan depletion (atd) to reduce the brain synthesis of serotonin (5-ht), which is thought to have a central role in regulation of emotions and mood in humans. |
2005-04-26 |
2023-08-12 |
human |
| A V Sergutina, L M Gershteĭ. [Morphochemical analysis of hippocampus of rats predisposed (August) or resistant (Wistar) to emotional stress]. Morfologiia (Saint Petersburg, Russia). vol 125. issue 2. 2005-02-18. PMID:15232864. |
using quantitative cytochemical methods it was demonstrated that the activities of aminopeptidase, monoaminooxidase (substrates--tryptamine and serotonin), and glutamate dehydrogenase, were lower in the hippocampus of august rats (predisposed to emotional stress) as compared to that one in wistar rats (resistant to emotional stress). |
2005-02-18 |
2023-08-12 |
rat |
| Rie Suzuki, Lars J Rygh, Anthony H Dickenso. Bad news from the brain: descending 5-HT pathways that control spinal pain processing. Trends in pharmacological sciences. vol 25. issue 12. 2005-02-09. PMID:15530638. |
in this article, we review evidence for facilitatory 5-ht pathways that link spinal cord and brainstem areas involved in mood and emotions. |
2005-02-09 |
2023-08-12 |
Not clear |
| Rie Suzuki, Lars J Rygh, Anthony H Dickenso. Bad news from the brain: descending 5-HT pathways that control spinal pain processing. Trends in pharmacological sciences. vol 25. issue 12. 2005-02-09. PMID:15530638. |
because pain encompasses affective aspects, we suggest that these 5-ht pathways and other circuits are important in determining the levels of pain, the outcome of drug treatments and provide a mechanism whereby emotions can alter pain perception. |
2005-02-09 |
2023-08-12 |
Not clear |
| P Zhong, Z Ya. Chronic antidepressant treatment alters serotonergic regulation of GABA transmission in prefrontal cortical pyramidal neurons. Neuroscience. vol 129. issue 1. 2005-01-13. PMID:15489029. |
in this study, we investigated the alteration of 5-ht functions by long-term antidepressant treatment in pyramidal neurons of prefrontal cortex (pfc), a brain region crucial for the control of emotion and cognition. |
2005-01-13 |
2023-08-12 |
Not clear |
| Huibing Tan, Ping Zhong, Zhen Ya. Corticotropin-releasing factor and acute stress prolongs serotonergic regulation of GABA transmission in prefrontal cortical pyramidal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 21. 2005-01-12. PMID:15163692. |
to understand the potential link between them, we investigated the impact of crf on 5-ht functions in pyramidal neurons of the prefrontal cortex (pfc), a brain region that is crucial for the control of emotion and cognition. |
2005-01-12 |
2023-08-12 |
Not clear |
| Mark S Ansorge, Mingming Zhou, Alena Lira, René Hen, Jay A Gingric. Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice. Science (New York, N.Y.). vol 306. issue 5697. 2004-11-22. PMID:15514160. |
early-life blockade of the 5-ht transporter alters emotional behavior in adult mice. |
2004-11-22 |
2023-08-12 |
mouse |
| Mark S Ansorge, Mingming Zhou, Alena Lira, René Hen, Jay A Gingric. Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice. Science (New York, N.Y.). vol 306. issue 5697. 2004-11-22. PMID:15514160. |
transient inhibition of 5-htt during early development with fluoxetine, a commonly used serotonin selective reuptake inhibitor, produced abnormal emotional behaviors in adult mice. |
2004-11-22 |
2023-08-12 |
mouse |
| Mark S Ansorge, Mingming Zhou, Alena Lira, René Hen, Jay A Gingric. Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice. Science (New York, N.Y.). vol 306. issue 5697. 2004-11-22. PMID:15514160. |
these findings indicate a critical role of serotonin in the maturation of brain systems that modulate emotional function in the adult and suggest a developmental mechanism to explain how low-expressing 5-htt promoter alleles increase vulnerability to psychiatric disorders. |
2004-11-22 |
2023-08-12 |
mouse |
| Lifen Zhang, Fu-Ming Zhou, John A Dan. Cholinergic drugs for Alzheimer's disease enhance in vitro dopamine release. Molecular pharmacology. vol 66. issue 3. 2004-11-03. PMID:15322245. |
the noncognitive aspects of dementia, however, are usually linked to serotonin and dopamine rather than acetylcholine because those neurotransmitter systems most directly influence mood, emotional balance, and psychosis. |
2004-11-03 |
2023-08-12 |
mouse |
| E Dere, M A De Souza-Silva, R E Spieler, J S Lin, H Ohtsu, H L Haas, J P Husto. Changes in motoric, exploratory and emotional behaviours and neuronal acetylcholine content and 5-HT turnover in histidine decarboxylase-KO mice. The European journal of neuroscience. vol 20. issue 4. 2004-10-14. PMID:15305873. |
changes in motoric, exploratory and emotional behaviours and neuronal acetylcholine content and 5-ht turnover in histidine decarboxylase-ko mice. |
2004-10-14 |
2023-08-12 |
mouse |
| Anushree Bhatnagar, Douglas J Sheffler, Wesley K Kroeze, BethAnn Compton-Toth, Bryan L Rot. Caveolin-1 interacts with 5-HT2A serotonin receptors and profoundly modulates the signaling of selected Galphaq-coupled protein receptors. The Journal of biological chemistry. vol 279. issue 33. 2004-09-24. PMID:15190056. |
5-hydroxytryptamine 2a (5-ht(2a)) serotonin receptors are important for a variety of functions including vascular smooth muscle contraction, platelet aggregation, and the modulation of perception, cognition, and emotion. |
2004-09-24 |
2023-08-12 |
rat |
| Andrew H Kemp, Marcus A Gray, Richard B Silberstein, Stuart M Armstrong, Pradeep J Natha. Augmentation of serotonin enhances pleasant and suppresses unpleasant cortical electrophysiological responses to visual emotional stimuli in humans. NeuroImage. vol 22. issue 3. 2004-09-16. PMID:15219580. |
the serotonergic system is one of the major systems targeted in the pharmacological treatment of a wide range of mood disorders including depression; however, little is known about the neurophysiological mechanisms underlying the effects of serotonin (5-ht) on affective phenomena including emotional behaviours, mood and emotional processing. |
2004-09-16 |
2023-08-12 |
human |
| Andrew H Kemp, Marcus A Gray, Richard B Silberstein, Stuart M Armstrong, Pradeep J Natha. Augmentation of serotonin enhances pleasant and suppresses unpleasant cortical electrophysiological responses to visual emotional stimuli in humans. NeuroImage. vol 22. issue 3. 2004-09-16. PMID:15219580. |
the aim of the current study was to investigate how 5-ht acutely modulates steady-state visually evoked potentials (ssvep), heart rate (hr) and verbal ratings associated with the viewing of differently valent emotional images. |
2004-09-16 |
2023-08-12 |
human |
| Katarina Varnäs, Christer Halldin, Håkan Hal. Autoradiographic distribution of serotonin transporters and receptor subtypes in human brain. Human brain mapping. vol 22. issue 3. 2004-09-08. PMID:15195291. |
the localization in regions belonging to limbic cortico-striato-pallido-thalamic circuits is in line with the documented role of 5-ht in modulation of mood and emotion, and the suggested involvement of this system in pathophysiology of various psychiatric disorders. |
2004-09-08 |
2023-08-12 |
human |
| Katsuji Takai, Eiko Ogiso-Nakamaru, Hiroyuki Miyamoto, Kozo Hamada, Koji Tsukad. Enzymatic depletion of serotonin in vivo and its consequences. Advances in experimental medicine and biology. vol 527. 2004-09-02. PMID:15206733. |
the serotonin (5-ht) system in the brain is a global modulator thought to tune up a unique subset of brain keynotes such as emotion, motivation, and sleep/conscious states in the deepest seats of cognition and behavior. |
2004-09-02 |
2023-08-12 |
Not clear |
| Klaus Peter Lesch, Yong Zeng, Andreas Reif, Lise Gutknech. Anxiety-related traits in mice with modified genes of the serotonergic pathway. European journal of pharmacology. vol 480. issue 1-3. 2004-07-22. PMID:14623362. |
in other instances, knockout studies have changed views of the relevance of 5-ht homeostasis in brain development and plasticity as well as processes underlying emotional behavior. |
2004-07-22 |
2023-08-12 |
mouse |
| Robert O Friede. Dopamine dysfunction in borderline personality disorder: a hypothesis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 6. 2004-07-14. PMID:15039763. |
alternatively, da dysfunction in bpd may be a compensatory response to alterations in the primary neural systems that control emotion, impulse control, and cognition, and that are mediated by the brain's main neurotransmitters, glutamate, and gaba, or in one or more other neuromodulatory pathways such as serotonin, acetylcholine, and norepinephrine. |
2004-07-14 |
2023-08-12 |
human |