Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Vincent J Aloyo, Kuldip D Dav. Behavioral response to emotional stress in rabbits: role of serotonin and serotonin2A receptors. Behavioural pharmacology. vol 18. issue 7. 2008-01-29. PMID:17912049. |
behavioral response to emotional stress in rabbits: role of serotonin and serotonin2a receptors. |
2008-01-29 |
2023-08-12 |
dog |
Glen I Spielman. Duloxetine does not relieve painful physical symptoms in depression: a meta-analysis. Psychotherapy and psychosomatics. vol 77. issue 1. 2008-01-29. PMID:18087203. |
duloxetine inhibits both serotonin and norepinephrine reuptake and is marketed as a treatment for both the core emotional symptoms and painful physical complaints that often accompany depression. |
2008-01-29 |
2023-08-12 |
Not clear |
A J Fulford, C A Marsde. An intact dopaminergic system is required for context-conditioned release of 5-HT in the nucleus accumbens of postweaning isolation-reared rats. Neuroscience. vol 149. issue 2. 2008-01-16. PMID:17869434. |
microdialysis with high-performance liquid chromatography-electrochemical detection was used to quantify dopamine and 5-ht efflux in the nucleus accumbens following foot shock and in association with a conditioned emotional response (cer). |
2008-01-16 |
2023-08-12 |
rat |
Kohtarou Konno, Machiko Matsumoto, Hiroko Togashi, Taku Yamaguchi, Takeshi Izumi, Masahiko Watanabe, Toshihiko Iwanaga, Mitsuhiro Yoshiok. Early postnatal stress affects the serotonergic function in the median raphe nuclei of adult rats. Brain research. vol 1172. 2008-01-09. PMID:17825274. |
recent studies have focused on the serotonergic mechanism mediated via serotonin (5-ht) receptors underlying regulation of emotional stress during the developmental period. |
2008-01-09 |
2023-08-12 |
rat |
Turhan Canli, Klaus-Peter Lesc. Long story short: the serotonin transporter in emotion regulation and social cognition. Nature neuroscience. vol 10. issue 9. 2008-01-04. PMID:17726476. |
long story short: the serotonin transporter in emotion regulation and social cognition. |
2008-01-04 |
2023-08-12 |
Not clear |
M A De Souza Silva, L Marchetti, U L M Eisel, J P Huston, E Der. NR2C by NR2B subunit exchange in juvenile mice affects emotionality and 5-HT in the frontal cortex. Genes, brain, and behavior. vol 6. issue 5. 2007-09-19. PMID:17054720. |
this nr2c-2b mutant was used to examine whether an nmda-r subunit exchange in juvenile mice would affect emotional behaviors and acetylcholine (ach), dopamine (da) and serotonin (5-ht) content in the frontal cortex (fc) and brain structures, which are part of the brain defense system, such as the periaqueductal grey matter (pag). |
2007-09-19 |
2023-08-12 |
mouse |
Markus Storvik, Jari Tiihonen, Tuija Haukijärvi, Erkki Tupal. Amygdala serotonin transporters in alcoholics measured by whole hemisphere autoradiography. Synapse (New York, N.Y.). vol 61. issue 8. 2007-09-12. PMID:17476685. |
the conjuncted alterations in functioning of serotonin transporter (sert) may play a role in the regulation of emotional balance, judgement, and the adverse behavioral effects of ethanol misuse. |
2007-09-12 |
2023-08-12 |
Not clear |
David J Miklowitz, Sheri L Johnso. The psychopathology and treatment of bipolar disorder. Annual review of clinical psychology. vol 2. 2007-09-11. PMID:17716069. |
it is characterized by dysregulation in the dopamine and serotonin systems and by pathology in the brain systems involved in regulating emotion. |
2007-09-11 |
2023-08-12 |
Not clear |
Esther Berrocoso, Juan Antonio Mic. In vivo effect of venlafaxine on locus coeruleus neurons: role of opioid, alpha(2)-adrenergic, and 5-hydroxytryptamine(1A) receptors. The Journal of pharmacology and experimental therapeutics. vol 322. issue 1. 2007-08-30. PMID:17431134. |
the locus coeruleus (lc) is involved in several neural pathways responsible for some somatic and emotional processes, such as pain and depression; its activity is regulated by several receptors, such as opioid, alpha(2)-adrenergic, and 5-hydroxytryptamine (5-ht)(1a) receptors. |
2007-08-30 |
2023-08-12 |
Not clear |
N V Maliuchenko, O V Sysoeva, A M Vediakov, M A Timofeeva, G V Portanova, A M Ivanitski, A G Tonevitski, M P Kirpichniko. [Effect of 5HTT genetic polymorphism on aggression in athletes]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 57. issue 3. 2007-08-20. PMID:17642369. |
genetic variations of serotonin transporter gene (5htt) are closely related with human adaptive ability to control emotions and are very attractive in investigation of athletes whose life is accompanied by high emotional pressure. |
2007-08-20 |
2023-08-12 |
human |
Michael Bauer, Hans-Jürgen Möller, Edith Schneide. Duloxetine: a new selective and dual-acting antidepressant. Expert opinion on pharmacotherapy. vol 7. issue 4. 2007-08-07. PMID:16503814. |
antidepressants that inhibit the re-uptake of serotonin and noradrenaline might offer a chance to reduce the multiple symptoms of depression, as both serotonin and noradrenaline seem to be responsible for the emotional and physical symptoms of depression. |
2007-08-07 |
2023-08-12 |
Not clear |
Jenna C Carroll, Janel M Boyce-Rustay, Rachel Millstein, Rebecca Yang, Lisa M Wiedholz, Dennis L Murphy, Andrew Holme. Effects of mild early life stress on abnormal emotion-related behaviors in 5-HTT knockout mice. Behavior genetics. vol 37. issue 1. 2007-07-25. PMID:17177116. |
a low-expressing polymorphic variant of the serotonin transporter (5-htt) gene has been associated with emotional disorders in humans and non-human primates following exposure to early life trauma. |
2007-07-25 |
2023-08-12 |
mouse |
Lise Gutknecht, Christian Jacob, Alexander Strobel, Claudia Kriegebaum, Johannes Müller, Yong Zeng, Christoph Markert, Andrea Escher, Jens Wendland, Andreas Reif, Rainald Mössner, Cornelius Gross, Burkhard Brocke, Klaus-Peter Lesc. Tryptophan hydroxylase-2 gene variation influences personality traits and disorders related to emotional dysregulation. The international journal of neuropsychopharmacology. vol 10. issue 3. 2007-07-20. PMID:17176492. |
these findings implicate alterations of 5-ht synthesis in emotion regulation and confirm tph2 as a susceptibility and/or modifier gene of affective spectrum disorders. |
2007-07-20 |
2023-08-12 |
Not clear |
Shigeo Miyata, Naoko Yamada, Shoko Hirano, Shun-ichi Tanaka, Junzo Kame. Diabetes attenuates psychological stress-elicited 5-HT secretion in the prefrontal cortex but not in the amygdala of mice. Brain research. vol 1147. 2007-07-16. PMID:17320057. |
however, no in vivo study assessed the serotonin (5-ht)-releasing system in the prefrontal cortex (pfc) and amygdala--the crucial regions regulating emotion. |
2007-07-16 |
2023-08-12 |
mouse |
M Häring, G Marsicano, B Lutz, K Monor. Identification of the cannabinoid receptor type 1 in serotonergic cells of raphe nuclei in mice. Neuroscience. vol 146. issue 3. 2007-07-03. PMID:17383106. |
our findings indicate that the cb1-mediated regulation of serotonin release can depend in part on a direct cross-talk between the two systems at single cell level, which might lead to functional implications in the modulation of emotional states. |
2007-07-03 |
2023-08-12 |
mouse |
B E H Sumner, K E Grant, R Rosie, Ch Hegele-Hartung, K-H Fritzemeier, G Fin. Raloxifene blocks estradiol induction of the serotonin transporter and 5-hydroxytryptamine2A receptor in female rat brain. Neuroscience letters. vol 417. issue 1. 2007-06-22. PMID:17398000. |
this is accompanied by an increase in the densities of 5-ht(2a)r and the sert in forebrain regions which in the human are concerned with the control of mood, mental state, cognition and emotion. |
2007-06-22 |
2023-08-12 |
human |
Zhenglin Gu, Qian Jiang, Zhen Ya. RGS4 modulates serotonin signaling in prefrontal cortex and links to serotonin dysfunction in a rat model of schizophrenia. Molecular pharmacology. vol 71. issue 4. 2007-06-04. PMID:17220354. |
activation of serotonin 5-ht(1a) receptors or dopamine d(4) receptors down-regulates the function of nmda receptor (nmdar) channel, a key player controlling cognition and emotion, in pyramidal neurons of prefrontal cortex (pfc). |
2007-06-04 |
2023-08-12 |
rat |
K P Lesch, R Mössne. Inactivation of 5HT transport in mice: modeling altered 5HT homeostasis implicated in emotional dysfunction, affective disorders, and somatic syndromes. Handbook of experimental pharmacology. issue 175. 2007-05-23. PMID:16722245. |
inactivation of 5ht transport in mice: modeling altered 5ht homeostasis implicated in emotional dysfunction, affective disorders, and somatic syndromes. |
2007-05-23 |
2023-08-12 |
mouse |
K P Lesch, R Mössne. Inactivation of 5HT transport in mice: modeling altered 5HT homeostasis implicated in emotional dysfunction, affective disorders, and somatic syndromes. Handbook of experimental pharmacology. issue 175. 2007-05-23. PMID:16722245. |
the combination of elaborate genetic, epigenetic, imaging, and behavioral analyses will continue to generate new insight into 5htt's role as a master control gene of emotion regulation. |
2007-05-23 |
2023-08-12 |
mouse |
Keith A Young, Leigh A Holcomb, Willy L Bonkale, Paul B Hicks, Umar Yazdani, Dwight C Germa. 5HTTLPR polymorphism and enlargement of the pulvinar: unlocking the backdoor to the limbic system. Biological psychiatry. vol 61. issue 6. 2007-04-26. PMID:17083920. |
the 5httlpr genetic variant of the serotonin transporter (sert), which consists of a long (sert-l) and short (sert-s) allele, has emerged as a major factor influencing emotional behavior and brain anatomy. |
2007-04-26 |
2023-08-12 |
Not clear |