| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jay-Maree Hughes, Cathy Matrenza, Andrew H Kemp, Ben J Harrison, David Liley, Pradeep J Natha. Selective effects of simultaneous monoamine depletion on mood and emotional responsiveness. The international journal of neuropsychopharmacology. vol 7. issue 1. 2004-05-07. PMID:14731308. |
while the selective effects of serotonin and catecholamine depletion on mood have been described, the effects of simultaneous monoamine depletion on subjective measures of mood and emotional responsiveness are yet to be examined. |
2004-05-07 |
2023-08-12 |
human |
| Sheryl G Beck, Yu-Zhen Pan, Adaure C Akanwa, Lynn G Kirb. Median and dorsal raphe neurons are not electrophysiologically identical. Journal of neurophysiology. vol 91. issue 2. 2004-03-31. PMID:14573555. |
the dorsal (dr) and median raphe (mr) nuclei contain 5-hydroxytryptamine (serotonin, 5-ht) cell bodies that give rise to the majority of the ascending 5-ht projections to the forebrain limbic areas that control emotional behavior. |
2004-03-31 |
2023-08-12 |
Not clear |
| Qian Li, Li Ma, Robert B Innis, Nicholas Seneca, Masanori Ichise, Henry Huang, Marc Laruelle, Dennis L Murph. Pharmacological and genetic characterization of two selective serotonin transporter ligands: 2-[2-(dimethylaminomethylphenylthio)]-5-fluoromethylphenylamine (AFM) and 3-amino-4-[2-(dimethylaminomethyl-phenylthio)]benzonitrile (DASB). The Journal of pharmacology and experimental therapeutics. vol 308. issue 2. 2004-03-11. PMID:14610240. |
the expression and function of the serotonin transporter (sert) is important in the regulation of mood and emotion. |
2004-03-11 |
2023-08-12 |
mouse |
| David J Goldstein, Yili Lu, Michael J Detke, James Hudson, Smriti Iyengar, Mark A Demitrac. Effects of duloxetine on painful physical symptoms associated with depression. Psychosomatics. vol 45. issue 1. 2004-02-12. PMID:14709757. |
the effect of the dual serotonin (5-ht) and norepinephrine reuptake inhibitor duloxetine on emotional and painful physical symptoms in outpatients with major depressive disorder was evaluated in three randomized, double-blind, placebo-controlled trials. |
2004-02-12 |
2023-08-12 |
human |
| A R Hariri, D R Weinberge. Functional neuroimaging of genetic variation in serotonergic neurotransmission. Genes, brain, and behavior. vol 2. issue 6. 2004-01-15. PMID:14653306. |
furthermore, genetic variation in 5-ht subsystem genes can impact upon several dimensions of emotional behavior including neuroticism and psychopathology, but especially anxiety traits. |
2004-01-15 |
2023-08-12 |
human |
| A R Hariri, D R Weinberge. Functional neuroimaging of genetic variation in serotonergic neurotransmission. Genes, brain, and behavior. vol 2. issue 6. 2004-01-15. PMID:14653306. |
recently, functional neuroimaging has provided a dramatic illustration of how a promoter polymorphism in the human 5-ht transporter (5-htt) gene, which has been weakly related to these behaviors, is strongly related to the engagement of neural systems, namely the amygdala, subserving emotional processes. |
2004-01-15 |
2023-08-12 |
human |
| A Holmes, Q Lit, D L Murphy, E Gold, J N Crawle. Abnormal anxiety-related behavior in serotonin transporter null mutant mice: the influence of genetic background. Genes, brain, and behavior. vol 2. issue 6. 2004-01-15. PMID:14653308. |
serotonin transporter (5-htt) null mutant mice provide a model system to study the role genetic variation in the 5-htt plays in the regulation of emotion. |
2004-01-15 |
2023-08-12 |
mouse |
| Silvana Chiavegatto, Randy J Nelso. Interaction of nitric oxide and serotonin in aggressive behavior. Hormones and behavior. vol 44. issue 3. 2003-12-17. PMID:14609545. |
recently, the excessive aggressive and impulsive traits of neuronal no synthase knockout (nnos-/-) mice were shown to be caused by reductions in serotonin (5-ht) turnover and deficient 5-ht1a and 5-ht1b receptor function in brain regions regulating emotion. |
2003-12-17 |
2023-08-12 |
mouse |
| Brian H Harvey, Carla Naciti, Linda Brand, Dan J Stei. Endocrine, cognitive and hippocampal/cortical 5HT 1A/2A receptor changes evoked by a time-dependent sensitisation (TDS) stress model in rats. Brain research. vol 983. issue 1-2. 2003-11-28. PMID:12914970. |
moreover, tds stress induces diverse adaptive 5ht receptor changes in critical brain areas involved in emotion and memory that may underlie the effect of stress on cognitive function. |
2003-11-28 |
2023-08-12 |
rat |
| Adam Opbroek, Pedro L Delgado, Cindi Laukes, Cindy McGahuey, Joanna Katsanis, Francisco A Moreno, Rachel Manbe. Emotional blunting associated with SSRI-induced sexual dysfunction. Do SSRIs inhibit emotional responses? The international journal of neuropsychopharmacology. vol 5. issue 2. 2003-11-21. PMID:12135539. |
anecdotal and published case reports suggest that some patients taking selective serotonin reuptake inhibitors (ssri) experience diminution in emotional responsiveness. |
2003-11-21 |
2023-08-12 |
Not clear |
| K Glatz, R Mössner, A Heils, K P Lesc. Glucocorticoid-regulated human serotonin transporter (5-HTT) expression is modulated by the 5-HTT gene-promotor-linked polymorphic region. Journal of neurochemistry. vol 86. issue 5. 2003-11-12. PMID:12911615. |
mood, emotion and cognition are modulated by serotonergic neurotransmission, while the physiological function of serotonergic synapses depends on serotonin reuptake, which is mediated by the serotonin transporter (5-htt). |
2003-11-12 |
2023-08-12 |
human |
| Timothy E Wilens, Joseph Biederman, Anne Kwon, Rhea Chase, Laura Greenberg, Eric Mick, Thomas J Spence. A systematic chart review of the nature of psychiatric adverse events in children and adolescents treated with selective serotonin reuptake inhibitors. Journal of child and adolescent psychopharmacology. vol 13. issue 2. 2003-10-21. PMID:12886909. |
despite a rapidly growing literature on the efficacy of the selective serotonin reuptake inhibitors (ssri) in the treatment of juvenile psychiatric disorders, relatively little is described about emotional, behavioral, and cognitive adverse effects associated with their use. |
2003-10-21 |
2023-08-12 |
Not clear |
| Menahem Krakowsk. Violence and serotonin: influence of impulse control, affect regulation, and social functioning. The Journal of neuropsychiatry and clinical neurosciences. vol 15. issue 3. 2003-09-24. PMID:12928505. |
the influence of serotonin is best analyzed within a broader framework that includes consideration of its role in the inhibition of impulses, the regulation of emotions and social functioning, domains that are closely linked to aggression. |
2003-09-24 |
2023-08-12 |
Not clear |
| Andrew Holmes, Jefferson W Kinney, Craige C Wrenn, Qian Li, Rebecca J Yang, Li Ma, Janani Vishwanath, Maria C Saavedra, Caitlin E Innerfield, Arie S Jacoby, John Shine, Tiina P Iismaa, Jacqueline N Crawle. Galanin GAL-R1 receptor null mutant mice display increased anxiety-like behavior specific to the elevated plus-maze. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 6. 2003-08-04. PMID:12700679. |
the neuropeptide galanin coexists with norepinephrine and serotonin in neural systems mediating emotion. |
2003-08-04 |
2023-08-12 |
mouse |
| A M S Kindlundh, J Lindblom, L Bergström, F Nyber. The anabolic-androgenic steroid nandrolone induces alterations in the density of serotonergic 5HT1B and 5HT2 receptors in the male rat brain. Neuroscience. vol 119. issue 1. 2003-07-28. PMID:12763073. |
in conclusion, serotonergic 5ht(1b) or 5ht(2) receptors are likely to play important roles in mediating observed emotional states and behavioral changes among aas abusers. |
2003-07-28 |
2023-08-12 |
rat |
| Mitchell K P Lai, Shirley W Y Tsang, Paul T Francis, Margaret M Esiri, Janet Keene, Tony Hope, Christopher P L-H Che. Reduced serotonin 5-HT1A receptor binding in the temporal cortex correlates with aggressive behavior in Alzheimer disease. Brain research. vol 974. issue 1-2. 2003-07-22. PMID:12742626. |
previous studies have implicated brain serotonin 5-ht(1a) receptors in several cns functions, including cognition, mood and emotional states. |
2003-07-22 |
2023-08-12 |
human |
| A E Umriukhin, A Wigger, N Singewald, R Landgra. Hypothalamic and hippocampal release of serotonin in rats bred for hyper- or hypo-anxiety. Stress (Amsterdam, Netherlands). vol 5. issue 4. 2003-05-21. PMID:12475735. |
we studied the release of hypothalamic and hippocampal serotonin in response to elevated platform exposure and forced swim stress, a mild emotional and a combined emotional and physical stressor, respectively. |
2003-05-21 |
2023-08-12 |
rat |
| M Valdez, T F Burke, J G Hensle. Selective heterologous regulation of 5-HT1A receptor-stimulated 35S GTPgammaS binding in the anterior cingulate cortex as a result of 5-HT2 receptor activation. Brain research. vol 957. issue 1. 2003-03-06. PMID:12443993. |
the heterologous regulation of 5-ht(1a) receptor function by chronic 5-ht(2) receptor activation in the anterior cingulate cortex raises interesting questions as to how the regulatory interaction between these serotonin receptor subtypes influences cognition, memory and emotion. |
2003-03-06 |
2023-08-12 |
rat |
| Janusz Szyndler, Paulina Rok, Piotr Maciejak, Jerzy Walkowiak, Agnieszka I Członkowska, Halina Sienkiewicz-Jarosz, Aleksandra Wisłowska, Małgorzata Zienowicz, Małgorzata Lehner, Andrzej Bidziński, Wojciech Kostowski, Adam Plazni. Effects of pentylenetetrazol-induced kindling of seizures on rat emotional behavior and brain monoaminergic systems. Pharmacology, biochemistry, and behavior. vol 73. issue 4. 2003-03-04. PMID:12213531. |
it is concluded that both da and 5-ht systems contribute to the emotional effects of ptz-induced kindling of seizures. |
2003-03-04 |
2023-08-12 |
rat |
| Timo Erkinjuntt. Treatment options: the latest evidence with galantamine (Reminyl). Journal of the neurological sciences. vol 203-204. 2003-01-23. PMID:12417370. |
this results from its potential to modulate systems involving other neurotransmitters such as 5-ht (serotonin) and dopamine, which affect mood and emotional balance. |
2003-01-23 |
2023-08-12 |
Not clear |