| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Julian Macoveanu, James B Rowe, Bettina Hornboll, Rebecca Elliott, Olaf B Paulson, Gitte M Knudsen, Hartwig R Siebne. Playing it safe but losing anyway--serotonergic signaling of negative outcomes in dorsomedial prefrontal cortex in the context of risk-aversion. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 8. 2014-03-13. PMID:23051938. |
however, it is unclear whether serotonin provides a neurobiological link between making a risk aversive decision and the response to a negative outcome. |
2014-03-13 |
2023-08-12 |
human |
| V P Nikitin, S V Solntsev. Peculiarities of amnesia development during memory reconsolidation impairment induced by isolated or combined treatment with neurotransmitter receptor antagonists. Bulletin of experimental biology and medicine. vol 155. issue 1. 2014-02-21. PMID:23667859. |
the effects of serotonin and glutamate receptor antagonists on conditioned food aversion memory reconsolidation were studied in experiments on edible snails. |
2014-02-21 |
2023-08-12 |
Not clear |
| N P Shugalev, A V Stavrovskaia, N G Iamshchikova, A S Ol'shanskiĭ, E A Kashirin. [Neurotensin influence on painful stress afteractions in rats with neurotoxic damages of serotoninergic structures of brain substantia nigra]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 63. issue 3. 2014-02-21. PMID:24450170. |
the prevention of this effect development after neurotensin administrations into caudate nucleus may be specified by recovery of recall passive avoidance reactions destroyed by neurotoxin action and is explained by normalization of relationships balance of 5-ht and dopaminergic brain systems. |
2014-02-21 |
2023-08-12 |
rat |
| Lukasz Piszczek, Kevin Schlax, Anna Wyrzykowska, Agnieszka Piszczek, Enrica Audero, Cornelius Thilo Gros. Serotonin 1A auto-receptors are not sufficient to modulate anxiety in mice. The European journal of neuroscience. vol 38. issue 4. 2014-02-19. PMID:23701504. |
mice lacking the serotonin 1a receptor (htr1a) show elevated avoidance of novel open spaces, suggesting that it has a role in modulating anxiety behavior. |
2014-02-19 |
2023-08-12 |
mouse |
| Dirk E M Geurts, Quentin J M Huys, Hanneke E M den Ouden, Roshan Cool. Serotonin and aversive Pavlovian control of instrumental behavior in humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 48. 2014-01-28. PMID:24285898. |
serotonin and aversive pavlovian control of instrumental behavior in humans. |
2014-01-28 |
2023-08-12 |
Not clear |
| Dirk E M Geurts, Quentin J M Huys, Hanneke E M den Ouden, Roshan Cool. Serotonin and aversive Pavlovian control of instrumental behavior in humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 48. 2014-01-28. PMID:24285898. |
here we investigate in humans the role of serotonin in such pavlovian-instrumental transfer in both the aversive and the appetitive domain using acute tryptophan depletion, known to lower central serotonin levels. |
2014-01-28 |
2023-08-12 |
Not clear |
| Dirk E M Geurts, Quentin J M Huys, Hanneke E M den Ouden, Roshan Cool. Serotonin and aversive Pavlovian control of instrumental behavior in humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 48. 2014-01-28. PMID:24285898. |
these data suggest that serotonin is selectively involved in pavlovian inhibition due to aversive expectations and have implications for our understanding of the mechanisms underlying a range of affective, impulsive, and aggressive neuropsychiatric disorders. |
2014-01-28 |
2023-08-12 |
Not clear |
| Cheryl L Grady, Hartwig R Siebner, Bettina Hornboll, Julian Macoveanu, Olaf B Paulson, Gitte M Knudse. Acute pharmacologically induced shifts in serotonin availability abolish emotion-selective responses to negative face emotions in distinct brain networks. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 5. 2013-12-27. PMID:22739125. |
using a within-subject design, we measured the effect of serotonin on the brain's response to aversive face emotions with functional mri while 20 participants judged the gender of neutral, fearful and angry faces. |
2013-12-27 |
2023-08-12 |
human |
| Cheryl L Grady, Hartwig R Siebner, Bettina Hornboll, Julian Macoveanu, Olaf B Paulson, Gitte M Knudse. Acute pharmacologically induced shifts in serotonin availability abolish emotion-selective responses to negative face emotions in distinct brain networks. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 5. 2013-12-27. PMID:22739125. |
lower serotonin leads to a broadening of a normally fear-specific response to anger, and higher levels reduce the differentiated brain response to aversive face emotions. |
2013-12-27 |
2023-08-12 |
human |
| Collin Challis, Janette Boulden, Avin Veerakumar, Julie Espallergues, Fair M Vassoler, R Christopher Pierce, Sheryl G Beck, Olivier Berto. Raphe GABAergic neurons mediate the acquisition of avoidance after social defeat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 35. 2013-10-28. PMID:23986235. |
serotonin (5-ht) modulates neural responses to socioaffective cues and can bias approach or avoidance behavioral decisions, yet the cellular mechanisms underlying its contribution to the regulation of social experiences remain poorly understood. |
2013-10-28 |
2023-08-12 |
mouse |
| Collin Challis, Janette Boulden, Avin Veerakumar, Julie Espallergues, Fair M Vassoler, R Christopher Pierce, Sheryl G Beck, Olivier Berto. Raphe GABAergic neurons mediate the acquisition of avoidance after social defeat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 35. 2013-10-28. PMID:23986235. |
we tested this hypothesis using whole-cell recording techniques in genetically identified drn gaba and 5-ht neurons in mice exposed to social defeat, a model that induces long-lasting avoidance behaviors in a subset of mice responsive to serotonergic antidepressants. |
2013-10-28 |
2023-08-12 |
mouse |
| Collin Challis, Janette Boulden, Avin Veerakumar, Julie Espallergues, Fair M Vassoler, R Christopher Pierce, Sheryl G Beck, Olivier Berto. Raphe GABAergic neurons mediate the acquisition of avoidance after social defeat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 35. 2013-10-28. PMID:23986235. |
furthermore, optogenetic silencing of drn gaba neurons disinhibited neighboring 5-ht neurons and prevented the acquisition of social avoidance in mice exposed to a social threat, but did not affect a previously acquired avoidance phenotype. |
2013-10-28 |
2023-08-12 |
mouse |
| Collin Challis, Janette Boulden, Avin Veerakumar, Julie Espallergues, Fair M Vassoler, R Christopher Pierce, Sheryl G Beck, Olivier Berto. Raphe GABAergic neurons mediate the acquisition of avoidance after social defeat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 35. 2013-10-28. PMID:23986235. |
we provide the first characterization of gaba neurons in the drn that monosynaptically inhibit 5-ht neurons and reveal their key role in neuroplastic processes underlying the development of social avoidance. |
2013-10-28 |
2023-08-12 |
mouse |
| Hong-Mei Wang, Li-Wei Wang, Xin-Min Liu, Chang-Lu Li, Shu-Ping Xu, Ahsana-Dar Faroo. Neuroprotective effects of forsythiaside on learning and memory deficits in senescence-accelerated mouse prone (SAMP8) mice. Pharmacology, biochemistry, and behavior. vol 105. 2013-10-23. PMID:23290932. |
forsythiaside (60, 120 and 240mg/kg) was orally administered to aged (8months old) samp8 mice for 45days followed by evaluating cognitive impairment (morris water maze and step-through passive avoidance), inflammation (interleukin-1β (il-1β) and interleukin-6 (il-6) levels), oxidative stress (glutathione peroxidase (gsh-px) and total superoxide dismutase (t-sod) activities; malondialdehyde (mda) and nitric oxide (no) contents) and neurotransmitter such as norepinephrine (ne), dopamine (da), 5-hydroxytryptamine (5-ht), glutamate (glu) gamma-aminobutyric acid (gaba) and acetyl choline (ach). |
2013-10-23 |
2023-08-12 |
mouse |
| Maria A Briscione, Katherine M Serafine, Andrew P Merluzzi, Kenner C Rice, Anthony L Rile. The effects of the 5-HT3 receptor antagonist tropisetron on cocaine-induced conditioned taste aversions. Pharmacology, biochemistry, and behavior. vol 105. 2013-10-23. PMID:23415734. |
cocaine induced dose-dependent taste aversions that were not blocked by tropisetron, suggesting that cocaine's aversive effects are not mediated by 5-ht, at least at this specific receptor subtype. |
2013-10-23 |
2023-08-12 |
rat |
| Kae Nakamur. The role of the dorsal raphé nucleus in reward-seeking behavior. Frontiers in integrative neuroscience. vol 7. 2013-08-29. PMID:23986662. |
anatomical and physiological evidence also revealed that the dorsal raphé nucleus (drn), a major source of serotonin, and the dopamine system receive common inputs from brain regions associated with appetitive and aversive information processing. |
2013-08-29 |
2023-08-12 |
Not clear |
| Tanel Visnapuu, Sirli Raud, Maarja Loomets, Riin Reimets, Silva Sütt, Hendrik Luuk, Mario Plaas, Sulev Kõks, Vallo Volke, Aet Alttoa, Jaanus Harro, Eero Vasa. Wfs1-deficient mice display altered function of serotonergic system and increased behavioral response to antidepressants. Frontiers in neuroscience. vol 7. 2013-08-05. PMID:23914152. |
we found that this aversive challenge caused a significant increase in the levels of 5-ht and 5-hydroxyindoleacetic acid (5-hiaa), a metabolite of 5-ht, in the ventral and dorsal striatum of wild-type mice, but not in their homozygous littermates. |
2013-08-05 |
2023-08-12 |
mouse |
| Walter H Kaye, Christina E Wierenga, Ursula F Bailer, Alan N Simmons, Amanda Bischoff-Greth. Nothing tastes as good as skinny feels: the neurobiology of anorexia nervosa. Trends in neurosciences. vol 36. issue 2. 2013-07-31. PMID:23333342. |
restricted eating may be a means of reducing negative mood caused by skewed interactions between serotonin aversive or inhibitory and dopamine reward systems. |
2013-07-31 |
2023-08-12 |
Not clear |
| Narattaphol Charoenphandhu, Amporn Nuntapornsak, Kannikar Wongdee, Nateetip Krishnamra, Jantarima Charoenphandh. Upregulated mRNA levels of SERT, NET, MAOB, and BDNF in various brain regions of ovariectomized rats exposed to chronic aversive stimuli. Molecular and cellular biochemistry. vol 375. issue 1-2. 2013-07-26. PMID:23208077. |
herein, we used quantitative real-time pcr to quantify the mrna levels of serotonin reuptake transporter (sert), norepinephrine transporter (net), monoamine oxidase-b (maob), tryptophan hydroxylase (tph), and tyrosine hydroxylase (th) in various brain regions of ovariectomized (ovx) rats which had been exposed for 4 weeks to chronic aversive stimuli (cas), such as water deprivation, cage tilt, and illumination. |
2013-07-26 |
2023-08-12 |
rat |
| Hidehiko Takahash. Monoamines and assessment of risks. Current opinion in neurobiology. vol 22. issue 6. 2013-05-22. PMID:22749131. |
circumstantial evidence suggests that dopamine tone might be related to distortion of subjective reward probability and noradrenaline and serotonin tone might influence aversive emotional reaction to potential loss. |
2013-05-22 |
2023-08-12 |
Not clear |