| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Martin N Hebart, Jan Gläsche. Serotonin and dopamine differentially affect appetitive and aversive general Pavlovian-to-instrumental transfer. Psychopharmacology. vol 232. issue 2. 2015-06-03. PMID:25034118. |
serotonin and dopamine differentially affect appetitive and aversive general pavlovian-to-instrumental transfer. |
2015-06-03 |
2023-08-13 |
human |
| Jesus G Ochoa, Alexandra Stolyarova, Amandeep Kaur, Evan E Hart, Amador Bugarin, Alicia Izquierd. Post-training depletions of basolateral amygdala serotonin fail to disrupt discrimination, retention, or reversal learning. Frontiers in neuroscience. vol 9. 2015-06-01. PMID:26029036. |
whereas, dopaminergic involvement is critical in behavioral activation and reinforcement, 5ht may be most critical for aversive processing and behavioral inhibition, complementary cognitive processes. |
2015-06-01 |
2023-08-13 |
rat |
| Kayoko W Miyazaki, Katsuhiko Miyazaki, Kenji F Tanaka, Akihiro Yamanaka, Aki Takahashi, Sawako Tabuchi, Kenji Doy. Optogenetic activation of dorsal raphe serotonin neurons enhances patience for future rewards. Current biology : CB. vol 24. issue 17. 2015-05-20. PMID:25155504. |
the classic theory on serotonin states that it opposes dopamine and inhibits behaviors when aversive events are predicted [9-14]. |
2015-05-20 |
2023-08-13 |
mouse |
| Benjamin D Sachs, Jason R Ni, Marc G Caro. Brain 5-HT deficiency increases stress vulnerability and impairs antidepressant responses following psychosocial stress. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 8. 2015-05-01. PMID:25675490. |
our results demonstrate that 5-ht deficiency leads to increased susceptibility to social defeat stress (sds), a model of psychosocial stress, and prevents the fluoxetine (flx)-induced reversal of sds-induced social avoidance, suggesting that 5-ht deficiency may impair antidepressant responses. |
2015-05-01 |
2023-08-13 |
mouse |
| Keiko Hirayama, Leonid L Moroz, Nathan G Hatcher, Rhanor Gillett. Neuromodulatory control of a goal-directed decision. PloS one. vol 9. issue 7. 2015-04-07. PMID:25048964. |
moreover, 5-ht switched the turn response to chemosensory stimulation from avoidance to orienting in many animals. |
2015-04-07 |
2023-08-13 |
Not clear |
| Keiko Hirayama, Leonid L Moroz, Nathan G Hatcher, Rhanor Gillett. Neuromodulatory control of a goal-directed decision. PloS one. vol 9. issue 7. 2015-04-07. PMID:25048964. |
in isolated cnss, bath application of 5-ht both stimulated activity in the feeding motor network and switched the fictive turn response to unilateral sensory nerve stimulation from avoidance to orienting. |
2015-04-07 |
2023-08-13 |
Not clear |
| Keiko Hirayama, Leonid L Moroz, Nathan G Hatcher, Rhanor Gillett. Neuromodulatory control of a goal-directed decision. PloS one. vol 9. issue 7. 2015-04-07. PMID:25048964. |
previously, it was shown that increasing excitation state of the feeding network reversibly switched the turn motor network response from avoidance to orienting, and that 5-ht levels vary inversely with nutritional state. |
2015-04-07 |
2023-08-13 |
Not clear |
| Jenifer Z Siegel, Molly J Crocket. How serotonin shapes moral judgment and behavior. Annals of the New York Academy of Sciences. vol 1299. 2015-04-02. PMID:25627116. |
we synthesize previous findings and consider the potential mechanisms through which serotonin could increase the aversion to harming others. |
2015-04-02 |
2023-08-13 |
Not clear |
| Matthew M For. Applications of schedule-induced polydipsia in rodents for the study of an excessive ethanol intake phenotype. Alcohol (Fayetteville, N.Y.). vol 48. issue 3. 2015-01-28. PMID:24680665. |
investigation of the stress axis and neurochemical systems such as dopamine and serotonin in mediating adjunctive drinking stemmed from two leading hypotheses regarding the underlying mechanisms of sip generation: 1) sip as a coping strategy to mitigate stress associated with the aversive environmental condition, and 2) sip as a displacement of reward in a highly motivated animal. |
2015-01-28 |
2023-08-12 |
mouse |
| Jfw Deaki. The origins of '5-HT and mechanisms of defence' by Deakin and Graeff: a personal perspective. Journal of psychopharmacology (Oxford, England). vol 27. issue 12. 2015-01-27. PMID:24067790. |
the principal insight was that different 5-ht pathways mediate distinct adaptive responses to aversive events of different types. |
2015-01-27 |
2023-08-12 |
human |
| Jfw Deaki. The origins of '5-HT and mechanisms of defence' by Deakin and Graeff: a personal perspective. Journal of psychopharmacology (Oxford, England). vol 27. issue 12. 2015-01-27. PMID:24067790. |
it emerged from a number of strands in neuropsychopharmacology: the functional implications of the still-fresh images of monoamine neuroanatomy of the 1970s; the ethological differentiation of behavioural responses to proximal and distal threats; and the seemingly contradictory effects of 5-ht drugs in unconditioned, pavlovian and instrumental paradigms of reward and aversion. |
2015-01-27 |
2023-08-12 |
human |
| Maria Adrielle Vicente, Helio Zangross. Serotonin-2C receptors in the basolateral nucleus of the amygdala mediate the anxiogenic effect of acute imipramine and fluoxetine administration. The international journal of neuropsychopharmacology. vol 15. issue 3. 2015-01-22. PMID:21733232. |
while intra-bla administration of 5-ht and mk-212 facilitated inhibitory avoidance acquisition, suggesting an anxiogenic effect, sb-242084 had the opposite effect. |
2015-01-22 |
2023-08-12 |
rat |
| Julian Macovean. Serotonergic modulation of reward and punishment: evidence from pharmacological fMRI studies. Brain research. vol 1556. 2014-11-06. PMID:24508910. |
the reviewed research has revealed how central serotonin availability and receptor specific transmission modulates the neural response to both appetitive (rewarding) and aversive (punishing) stimuli in putative reward-related brain regions. |
2014-11-06 |
2023-08-12 |
human |
| A B Klein, L Ultved, D Adamsen, M A Santini, A Tobeña, A Fernandez-Teruel, P Flores, M Moreno, D Cardona, G M Knudsen, S Aznar, J D Mikkelse. 5-HT(2A) and mGlu2 receptor binding levels are related to differences in impulsive behavior in the Roman Low- (RLA) and High- (RHA) avoidance rat strains. Neuroscience. vol 263. 2014-10-31. PMID:24412375. |
5-ht(2a) and mglu2 receptor binding levels are related to differences in impulsive behavior in the roman low- (rla) and high- (rha) avoidance rat strains. |
2014-10-31 |
2023-08-12 |
rat |
| Pascal Fossat, Julien Bacqué-Cazenave, Philippe De Deurwaerdère, Jean-Paul Delbecque, Daniel Cattaer. Comparative behavior. Anxiety-like behavior in crayfish is controlled by serotonin. Science (New York, N.Y.). vol 344. issue 6189. 2014-06-23. PMID:24926022. |
serotonin injection into unstressed crayfish induced avoidance; again, this effect was reversed by injection with chlordiazepoxide. |
2014-06-23 |
2023-08-13 |
Not clear |
| Joel Weinberger, Rebecca Klape. Environmental concentrations of the selective serotonin reuptake inhibitor fluoxetine impact specific behaviors involved in reproduction, feeding and predator avoidance in the fish Pimephales promelas (fathead minnow). Aquatic toxicology (Amsterdam, Netherlands). vol 151. 2014-05-22. PMID:24210950. |
environmental concentrations of the selective serotonin reuptake inhibitor fluoxetine impact specific behaviors involved in reproduction, feeding and predator avoidance in the fish pimephales promelas (fathead minnow). |
2014-05-22 |
2023-08-12 |
Not clear |
| Derrik E Asher, Alexis B Craig, Andrew Zaldivar, Alyssa A Brewer, Jeffrey L Krichma. A dynamic, embodied paradigm to investigate the role of serotonin in decision-making. Frontiers in integrative neuroscience. vol 7. 2014-04-22. PMID:24319413. |
serotonin (5-ht) is a neuromodulator that has been attributed to cost assessment and harm aversion. |
2014-04-22 |
2023-08-12 |
human |
| Ursula F Bailer, Guido K Frank, Julie C Price, Carolyn C Meltzer, Carl Becker, Chester A Mathis, Angela Wagner, Nicole C Barbarich-Marsteller, Cinnamon S Bloss, Karen Putnam, Nicholas J Schork, Anthony Gamst, Walter H Kay. Interaction between serotonin transporter and dopamine D2/D3 receptor radioligand measures is associated with harm avoidant symptoms in anorexia and bulimia nervosa. Psychiatry research. vol 211. issue 2. 2014-04-21. PMID:23154100. |
based on theories that 5-ht is an aversive motivational system that may oppose a da-related appetitive system, we explored interactions of positron emission tomography (pet) radioligand measures that reflect portions of these systems. |
2014-04-21 |
2023-08-12 |
Not clear |
| Iu O Fedotova, N S Saprono. [Co-administration of NAN-190 with low dose of testosterone propionate improves passive avoidance performance in rats with androgen deficiency]. Eksperimental'naia i klinicheskaia farmakologiia. vol 76. issue 12. 2014-04-07. PMID:24605422. |
we have studied the effect of stimulation or blockade of the 5-ht(1a) receptors on the passive avoidance performance and open-field test behavior in gonadectomized (gdx) male rats of middle age treated with a low dose of testosterone propionate. |
2014-04-07 |
2023-08-12 |
rat |
| Hiroki Shikanai, Shinichi Kimura, Hiroko Togash. Early life stress affects the serotonergic system underlying emotional regulation. Biological & pharmaceutical bulletin. vol 36. issue 9. 2014-04-01. PMID:23995647. |
an aversive stimulus, foot shock (fs), during the early postnatal period (2-3 weeks after birth) produced behavioral, neuroanatomical and electrophysiological changes accompanied by serotonergic dysfunction, especially functional impairment of the serotonin (5-hydroxytryptamine; 5-ht)1a receptor in the cortico-limbic area. |
2014-04-01 |
2023-08-12 |
rat |