| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Liangyue Lu, Qian Zhang, Man Ren, Erhui Jin, Qianqian Hu, Chunfang Zhao, Shenghe L. Effects of Boron on Cytotoxicity, Apoptosis, and Cell Cycle of Cultured Rat Sertoli Cells In vitro. Biological trace element research. vol 196. issue 1. 2021-03-15. PMID:31656015. |
cell apoptosis and cycle of scs were analyzed using flow cytometry. |
2021-03-15 |
2023-08-13 |
rat |
| Hossein Kargar Jahromi, Ali Farzin, Elham Hasanzadeh, Somayeh Ebrahimi Barough, Narges Mahmoodi, Mohammad Reza H Najafabadi, Morteza Sagharjoghi Farahani, Korosh Mansoori, Sadegh Shirian, Jafar A. Enhanced sciatic nerve regeneration by poly-L-lactic acid/multi-wall carbon nanotube neural guidance conduit containing Schwann cells and curcumin encapsulated chitosan nanoparticles in rat. Materials science & engineering. C, Materials for biological applications. vol 109. 2020-12-24. PMID:32228906. |
scs play an important role in the regeneration of injured peripheral nerve and controlled curcumin release can decrease scs apoptosis, and enhance the regeneration and functional recovery of injured peripheral nerves. |
2020-12-24 |
2023-08-13 |
rat |
| Silvia Magalhães-Novais, Juan C Bermejo-Millo, Rute Loureiro, Katia A Mesquita, M Rosário Domingues, Elisabete Maciel, Tânia Melo, Inês Baldeiras, Jenna R Erickson, Jon Holy, Yaiza Potes, Ana Coto-Montes, Paulo J Oliveira, Ignacio Vega-Nared. Cell quality control mechanisms maintain stemness and differentiation potential of P19 embryonic carcinoma cells. Autophagy. vol 16. issue 2. 2020-11-23. PMID:30990357. |
in addition, p19scs pluripotency was correlated with stronger antioxidant protection, modulation of apoptosis, and activation of macroautophagy, which all contributed to preserve scs quality by increasing the threshold for cell death activation. |
2020-11-23 |
2023-08-13 |
Not clear |
| Maoying Zhu, Juan Lu, Jianyun Shen, Lumin Fei, Deyu Che. A 22-amino-acid peptide regulates tight junctions through occludin and cell apoptosis. PeerJ. vol 8. 2020-11-17. PMID:33194394. |
in this study, a 22aa-induced tj destruction animal model was constructed to investigate the effect of 22aa on sertoli cells (scs) and spermatid counts and cell apoptosis at different time points using a multiplex immunofluorescence technique. |
2020-11-17 |
2023-08-13 |
mouse |
| Takashi Hasebe, Kenta Fujimoto, Daniel R Buchholz, Atsuko Ishizuya-Ok. Stem cell development involves divergent thyroid hormone receptor subtype expression and epigenetic modifications in the Xenopus metamorphosing intestine. General and comparative endocrinology. vol 292. 2020-10-29. PMID:32084349. |
in the intestine during metamorphosis of the frog xenopus laevis, most of the larval epithelial cells are induced to undergo apoptosis by thyroid hormone (th), and under continued th action, the remaining epithelial cells dedifferentiate into stem cells (scs), which then newly generate an adult epithelium analogous to the mammalian intestinal epithelium. |
2020-10-29 |
2023-08-13 |
xenopus_laevis |
| Lvpeng Dong, Rui Li, Duohui Li, Beini Wang, Yingfeng Lu, Peifeng Li, Fangzheng Yu, Yonglong Jin, Xiao Ni, Yanqing Wu, Shengnan Yang, Guanxi Lv, Xiaokun Li, Jian Xiao, Jian Wan. FGF10 Enhances Peripheral Nerve Regeneration Frontiers in pharmacology. vol 10. 2020-10-01. PMID:31680984. |
moreover, exogenous fgf10 treatment also prevented scs from excessive oxidative stress-induced apoptosis, which was probably related to the activation of phosphatidylinositol-3 kinase/protein kinase b (pi3k/akt) signaling. |
2020-10-01 |
2023-08-13 |
Not clear |
| Huan Li, Zihui Yang, Weiqi Wang, Jun Wang, Jianying Zhang, Junye Liu, Tao Yang, Yaowu Yang, Jianhua Wei, Delin Lei, Xinjie Yan. NT-3/TrkC Axis Contributes to the Perineural Invasion and the Poor Prognosis in Human Salivary Adenoid Cystic Carcinoma. Journal of Cancer. vol 10. issue 24. 2020-10-01. PMID:31762816. |
under the stimulation of nt-3, the directional motor ability of sacc-83 cells and scs was significantly improved, and the apoptosis of sacc-83 cells and scs were obviously inhibited. |
2020-10-01 |
2023-08-13 |
human |
| Weijie Yao, Xinwei Yang, Jiayue Zhu, Biane Gao, Renhui Liu, Liping X. Tang-Luo-Ning, a Traditional Chinese Medicine, Inhibits Endoplasmic Reticulum Stress-Induced Apoptosis of Schwann Cells under High Glucose Environment. Evidence-based complementary and alternative medicine : eCAM. vol 2017. 2020-09-30. PMID:29362588. |
schwann cells (scs) apoptosis induced by endoplasmic reticulum stress (er stress) is one of the main pathogeneses of dpn. |
2020-09-30 |
2023-08-13 |
Not clear |
| Weijie Yao, Xinwei Yang, Jiayue Zhu, Biane Gao, Renhui Liu, Liping X. Tang-Luo-Ning, a Traditional Chinese Medicine, Inhibits Endoplasmic Reticulum Stress-Induced Apoptosis of Schwann Cells under High Glucose Environment. Evidence-based complementary and alternative medicine : eCAM. vol 2017. 2020-09-30. PMID:29362588. |
this study investigates whether tln can inhibit scs apoptosis by inhibiting er stress-induced apoptosis. |
2020-09-30 |
2023-08-13 |
Not clear |
| D C Oran, T Lokumcu, Y Inceoglu, M B Akolpoglu, O Albayrak, T Bal, M Kurtoglu, M Erkan, F Can, T Bagci-Onder, S Kizile. Engineering human stellate cells for beta cell replacement therapy promotes Materials today. Bio. vol 2. 2020-09-28. PMID:32159143. |
stellate cells (scs) have various immunomodulatory functions: recruitment of tregs and induction of t-cell apoptosis. |
2020-09-28 |
2023-08-13 |
mouse |
| Jianhua Zhou, Shengyou Li, Jianbo Gao, Yawei Hu, Shaochu Chen, Xinle Luo, Hao Zhang, Zhuojing Luo, Jinghui Huan. Epothilone B Facilitates Peripheral Nerve Regeneration by Promoting Autophagy and Migration in Schwann Cells. Frontiers in cellular neuroscience. vol 14. 2020-09-28. PMID:32528253. |
also, epob (1 nm) did not result in significant apoptosis in schwann cells (scs) and showed little effect on their viability either. |
2020-09-28 |
2023-08-13 |
rat |
| Jiang-Bo Wang, Zhan Zhang, Jian-Nan Li, Tuo Yang, Shuang Du, Rang-Juan Cao, Shu-Sen Cu. SPP1 promotes Schwann cell proliferation and survival through PKCα by binding with CD44 and αvβ3 after peripheral nerve injury. Cell & bioscience. vol 10. 2020-09-28. PMID:32843960. |
the expression of genes in scs undergo a series of changes, which greatly affect the proliferation and apoptosis of scs as well as the fate of peripheral nerve regeneration. |
2020-09-28 |
2023-08-13 |
Not clear |
| Jiang-Bo Wang, Zhan Zhang, Jian-Nan Li, Tuo Yang, Shuang Du, Rang-Juan Cao, Shu-Sen Cu. SPP1 promotes Schwann cell proliferation and survival through PKCα by binding with CD44 and αvβ3 after peripheral nerve injury. Cell & bioscience. vol 10. 2020-09-28. PMID:32843960. |
however, how do these genes regulate the proliferation and apoptosis of scs remains unclear. |
2020-09-28 |
2023-08-13 |
Not clear |
| Kaixin Li, Xiaoxia Shi, Mengxin Luo, Inam-U-Llah, Pingan Wu, Mengren Zhang, Cong Zhang, Qiujuan Li, Yachen Wang, Fengyuan Pia. Taurine protects against myelin damage of sciatic nerve in diabetic peripheral neuropathy rats by controlling apoptosis of schwann cells via NGF/Akt/GSK3β pathway. Experimental cell research. vol 383. issue 2. 2020-06-29. PMID:31415759. |
diabetic peripheral neuropathy is a common complications of type 2 diabetes and its main pathological feature is myelin sheath damage of peripheral nerve that was induced by schwann cells (scs) apoptosis. |
2020-06-29 |
2023-08-13 |
rat |
| Kaixin Li, Xiaoxia Shi, Mengxin Luo, Inam-U-Llah, Pingan Wu, Mengren Zhang, Cong Zhang, Qiujuan Li, Yachen Wang, Fengyuan Pia. Taurine protects against myelin damage of sciatic nerve in diabetic peripheral neuropathy rats by controlling apoptosis of schwann cells via NGF/Akt/GSK3β pathway. Experimental cell research. vol 383. issue 2. 2020-06-29. PMID:31415759. |
increasing evidence suggested that taurine might play a role in improving dpn because of its ability to prevent scs apoptosis. |
2020-06-29 |
2023-08-13 |
rat |
| Kaixin Li, Xiaoxia Shi, Mengxin Luo, Inam-U-Llah, Pingan Wu, Mengren Zhang, Cong Zhang, Qiujuan Li, Yachen Wang, Fengyuan Pia. Taurine protects against myelin damage of sciatic nerve in diabetic peripheral neuropathy rats by controlling apoptosis of schwann cells via NGF/Akt/GSK3β pathway. Experimental cell research. vol 383. issue 2. 2020-06-29. PMID:31415759. |
in this study, we explore the effect of taurine on preventing scs apoptosis and its underlying mechanism. |
2020-06-29 |
2023-08-13 |
rat |
| Kaixin Li, Xiaoxia Shi, Mengxin Luo, Inam-U-Llah, Pingan Wu, Mengren Zhang, Cong Zhang, Qiujuan Li, Yachen Wang, Fengyuan Pia. Taurine protects against myelin damage of sciatic nerve in diabetic peripheral neuropathy rats by controlling apoptosis of schwann cells via NGF/Akt/GSK3β pathway. Experimental cell research. vol 383. issue 2. 2020-06-29. PMID:31415759. |
results showed that taurine significantly corrected morphology of damaged myelin sheath and inhibited scs apoptosis in sciatic nerve of diabetic rats. |
2020-06-29 |
2023-08-13 |
rat |
| Kaixin Li, Xiaoxia Shi, Mengxin Luo, Inam-U-Llah, Pingan Wu, Mengren Zhang, Cong Zhang, Qiujuan Li, Yachen Wang, Fengyuan Pia. Taurine protects against myelin damage of sciatic nerve in diabetic peripheral neuropathy rats by controlling apoptosis of schwann cells via NGF/Akt/GSK3β pathway. Experimental cell research. vol 383. issue 2. 2020-06-29. PMID:31415759. |
these results revealed taurine improved the myelin sheath damage of sciatic nerve in diabetic rats by controlling scs apoptosis via ngf/akt/gsk3β signaling pathways, which provides some clues that taurine might be effective and feasible candidate for the treatment of dpn. |
2020-06-29 |
2023-08-13 |
rat |
| Abbas Aliaghaei, Arman Zeinaddini Meymand, Mahdi Eskandarian Boroujeni, Fariba Khodagoli, Gholam Houssein Meftahi, Mohammad Mehdi Hadipour, Mohammad Amin Abdollahifar, Somaye Mesgar, Houssein Ahmadi, Samira Danyali, Sanaz Hasani, Yousef Sadegh. Neuro-restorative effect of sertoli cell transplants in a rat model of amyloid beta toxicity. Behavioural brain research. vol 367. 2020-06-08. PMID:30905711. |
according to our in vivo results, implanted scs survived, exhibited reduction in both apoptosis as well as astrocytic migration. |
2020-06-08 |
2023-08-13 |
rat |
| Wen Li, Yonghan He, Rongping Zhang, Guangrong Zheng, Daohong Zho. The curcumin analog EF24 is a novel senolytic agent. Aging. vol 11. issue 2. 2020-04-03. PMID:30694217. |
mechanistically, ef24 selectively kills scs by inducing sc apoptosis in a reactive oxygen species (ros) production independent manner but associated with an increase in the proteasome degradation of the bcl-2 anti-apoptotic protein family proteins known to play an important role in protecting scs from apoptosis. |
2020-04-03 |
2023-08-13 |
Not clear |