Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Xianrong Xiong, Xingyu Min, Hailing Yu, Xixi Fei, Yanjin Zhu, Bangting Pan, Yan Xiong, Wei Fu, Jian L. MicroRNA-34b-5p targets PPP1R11 to inhibit proliferation and promote apoptosis in cattleyak Sertoli cells by regulating specific signaling pathways. Theriogenology. vol 194. 2022-10-09. PMID:36209544. |
thus, mir-34b-5p regulates the apoptosis and proliferation of cattleyak scs via targeting ppp1r11, which can provide an innovative direction for exploring the mechanism of cattleyak male sterility. |
2022-10-09 |
2023-08-14 |
Not clear |
Mengqi Liu, Zhengkai Yue, Bin Zhang, Fan Li, Lei Liu, Fuchang L. mTORC1 Mediates the Processes of Lysine Regulating Satellite Cells Proliferation, Apoptosis, and Autophagy. Metabolites. vol 12. issue 9. 2022-09-23. PMID:36144192. |
the results show lys deprivation significantly decreases scs viability, protein synthesis, and cell cycling, increases autophagy and apoptosis, and inhibits the mtorc1 signaling pathway. |
2022-09-23 |
2023-08-14 |
Not clear |
Mengqi Liu, Zhengkai Yue, Bin Zhang, Fan Li, Lei Liu, Fuchang L. mTORC1 Mediates the Processes of Lysine Regulating Satellite Cells Proliferation, Apoptosis, and Autophagy. Metabolites. vol 12. issue 9. 2022-09-23. PMID:36144192. |
mtorc1 signaling pathway activation during lys deprivation or mtorc1 signaling pathway inhibition during lys addition attenuates the effect of lys deprivation or addition on scs viability, protein synthesis, cell cycling, autophagy, and apoptosis. |
2022-09-23 |
2023-08-14 |
Not clear |
Mengqi Liu, Zhengkai Yue, Bin Zhang, Fan Li, Lei Liu, Fuchang L. mTORC1 Mediates the Processes of Lysine Regulating Satellite Cells Proliferation, Apoptosis, and Autophagy. Metabolites. vol 12. issue 9. 2022-09-23. PMID:36144192. |
in conclusion, lys could improve scs proliferation, and inhibit scs apoptosis and autophagy, via the mtorc1 signaling pathway. |
2022-09-23 |
2023-08-14 |
Not clear |
Xuejiao An, Taotao Li, Nana Chen, Huihui Wang, Manchun Su, Huibin Shi, Xinming Duan, Youji M. miR-1285-3p targets TPI1 to regulate the glycolysis metabolism signaling pathway of Tibetan sheep Sertoli cells. PloS one. vol 17. issue 9. 2022-09-22. PMID:36137140. |
on the basis of a previous research, we isolated primary scs from tibetan sheep, and overexpressed tpi1 gene to determine its effect on the proliferation, glycolysis, and apoptosis of scs. |
2022-09-22 |
2023-08-14 |
Not clear |
Xuejiao An, Taotao Li, Nana Chen, Huihui Wang, Manchun Su, Huibin Shi, Xinming Duan, Youji M. miR-1285-3p targets TPI1 to regulate the glycolysis metabolism signaling pathway of Tibetan sheep Sertoli cells. PloS one. vol 17. issue 9. 2022-09-22. PMID:36137140. |
secondly, we investigated the relationship between tpi1 and mir-1285-3p, and whether mir-1285-3p regulates the proliferation and apoptosis of scs, and participates in glycolysis by targeting tpi1. |
2022-09-22 |
2023-08-14 |
Not clear |
Xuejiao An, Taotao Li, Nana Chen, Huihui Wang, Manchun Su, Huibin Shi, Xinming Duan, Youji M. miR-1285-3p targets TPI1 to regulate the glycolysis metabolism signaling pathway of Tibetan sheep Sertoli cells. PloS one. vol 17. issue 9. 2022-09-22. PMID:36137140. |
results showed that overexpression of tpi1 increased the proliferation rate and decreased apoptosis of scs. |
2022-09-22 |
2023-08-14 |
Not clear |
Taiding Wu, Xin Li, Shiwei Tu, Wenbo Tan, Longju Che. Curcumin protect Schwann cells from inflammation response and apoptosis induced by high glucose through the NF-κB pathway. Tissue & cell. vol 77. 2022-07-22. PMID:35868051. |
demyelination disease as diabetes mellitus (dm) complication is characterized by apoptosis of schwann cells (scs) and several reports have demonstrated that high glucose content can induce an inflammation response and lead to the apoptosis of scs. |
2022-07-22 |
2023-08-14 |
Not clear |
Taiding Wu, Xin Li, Shiwei Tu, Wenbo Tan, Longju Che. Curcumin protect Schwann cells from inflammation response and apoptosis induced by high glucose through the NF-κB pathway. Tissue & cell. vol 77. 2022-07-22. PMID:35868051. |
our cumulative findings suggest that curcumin can protect scs from apoptosis through the inhibition of the inflammatory response though the nf-κb pathway. |
2022-07-22 |
2023-08-14 |
Not clear |
Qianqian Jiang, Qiannan Di, Dandan Shan, Qian X. Nonylphenol inhibited HIF-1alpha regulated aerobic glycolysis and induced ROS mediated apoptosis in rat Sertoli cells. Ecotoxicology and environmental safety. vol 241. 2022-07-01. PMID:35777343. |
nonylphenol (np) is an endocrine disruptor with reproductive toxicity, which can induce apoptosis of sertoli cells (scs). |
2022-07-01 |
2023-08-14 |
rat |
Qianqian Jiang, Qiannan Di, Dandan Shan, Qian X. Nonylphenol inhibited HIF-1alpha regulated aerobic glycolysis and induced ROS mediated apoptosis in rat Sertoli cells. Ecotoxicology and environmental safety. vol 241. 2022-07-01. PMID:35777343. |
this study aimed to investigate whether np can alter hif-1α-regulated aerobic glycolysis metabolism and thus induce apoptosis in rat scs. |
2022-07-01 |
2023-08-14 |
rat |
Sabrina Petricca, Giuseppe Celenza, Carla Luzi, Benedetta Cinque, Anna Rita Lizzi, Nicola Franceschini, Claudio Festuccia, Roberto Iori. Synergistic Activity of Ketoconazole and Miconazole with Prochloraz in Inducing Oxidative Stress, GSH Depletion, Mitochondrial Dysfunction, and Apoptosis in Mouse Sertoli TM4 Cells. International journal of molecular sciences. vol 23. issue 10. 2022-05-28. PMID:35628239. |
n-acetylcysteine (nac) inhibits ros accumulation and rescues scs from azole-induced apoptosis. |
2022-05-28 |
2023-08-13 |
mouse |
Wenxuan Zhang, Ziqiang Lin, Ailing Sun, Yongyong Shi, Qingxiong Hong, Gaofeng Zha. Curcumin ameliorates the experimental diabetic peripheral neuropathy through promotion of NGF expression in rats. Chemistry & biodiversity. 2022-05-10. PMID:35538560. |
increasing evidence suggested that inhibiting the apoptosis of schwann cells (scs) and promoting nerve growth factor (ngf) expression in sciatic nerves play key roles in preventing the onset of diabetic peripheral neuropathy (dpn). |
2022-05-10 |
2023-08-13 |
rat |
Wenxuan Zhang, Ziqiang Lin, Ailing Sun, Yongyong Shi, Qingxiong Hong, Gaofeng Zha. Curcumin ameliorates the experimental diabetic peripheral neuropathy through promotion of NGF expression in rats. Chemistry & biodiversity. 2022-05-10. PMID:35538560. |
the scs apoptosis in sciatic nerves was stained using tunel kit. |
2022-05-10 |
2023-08-13 |
rat |
Wenxuan Zhang, Ziqiang Lin, Ailing Sun, Yongyong Shi, Qingxiong Hong, Gaofeng Zha. Curcumin ameliorates the experimental diabetic peripheral neuropathy through promotion of NGF expression in rats. Chemistry & biodiversity. 2022-05-10. PMID:35538560. |
curcumin (50, 100 and 150 mg/kg) reduced scs apoptosis in sciatic nerves. |
2022-05-10 |
2023-08-13 |
rat |
Xiaoling Zeng, Luyuan Xie, Yuxin Ge, Yue Zhou, Hui Wang, Yongyi Chen, Xiaomei Zhu, Huayun Liu, Qianjin Liao, Yu Kong, Lijun Pan, Junjun Li, Lei Xue, Sha Li, Xiao Zhou, Chunmeng Shi, Xiaowu Shen. Satellite Cells are Activated in a Rat Model of Radiation-Induced Muscle Fibrosis. Radiation research. 2022-03-16. PMID:35294551. |
apoptosis and autophagy levels, il-1β concentrations in serum and irradiated skin tissues, and the numbers of scs and central nuclear muscle fibers were increased in the irradiated groups when compared with the control group. |
2022-03-16 |
2023-08-13 |
rat |
Hsu-Wen Tseng, Dorothée Girard, Kylie A Alexander, Susan M Millard, Frédéric Torossian, Adrienne Anginot, Whitney Fleming, Jules Gueguen, Marie-Emmanuelle Goriot, Denis Clay, Beulah Jose, Bianca Nowlan, Allison R Pettit, Marjorie Salga, François Genêt, Marie-Caroline Le Bousse-Kerdilès, Sébastien Banzet, Jean-Pierre Lévesqu. Spinal cord injury reprograms muscle fibroadipogenic progenitors to form heterotopic bones within muscles. Bone research. vol 10. issue 1. 2022-02-26. PMID:35217633. |
these experiments demonstrate that following muscle injury, sci causes the upregulation of pdgfrα expression on faps but not scs and the failure of scs to regenerate myofibers in the injured muscle, with reduced apoptosis and continued proliferation of muscle resident faps enabling their osteogenic differentiation into nhos. |
2022-02-26 |
2023-08-13 |
mouse |
Malikeh Rad Niknam, Farnoosh Attar. The Potential Applications of Stem Cells for Cancer Treatment. Current stem cell research & therapy. vol 17. issue 1. 2022-01-20. PMID:35048802. |
in this regard, engineered scs can secrete anti-cancer proteins or express enzymes used in suicide gene therapy which locally induce apoptosis in neoplastic cells via the bystander effect. |
2022-01-20 |
2023-08-13 |
Not clear |
Chen He, Jing Sun, Donghui Yang, Wenlai He, Jingyi Wang, Dezhe Qin, Huimin Zhang, Hui Cai, Yundie Liu, Na Li, Jinlian Hua, Sha Pen. Nrf2 activation mediates the protection of mouse Sertoli Cells damage under acute heat stress conditions. Theriogenology. vol 177. 2021-11-22. PMID:34715543. |
we found that acute heat stress only affected the vitality of scs and the expression of functional molecules (tight junction-associated proteins and lactate dehydrogenase a [ldha]) but did not cause cell apoptosis. |
2021-11-22 |
2023-08-13 |
mouse |
Mingxia Ge, Li Hu, Hongshun Ao, Meiting Zi, Qingpeng Kong, Yonghan H. Senolytic targets and new strategies for clearing senescent cells. Mechanisms of ageing and development. vol 195. 2021-11-19. PMID:33741395. |
scs are resistant to various stressors because they are protected from apoptosis by sc anti-apoptotic pathways (scaps). |
2021-11-19 |
2023-08-13 |
Not clear |