| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anna Geueke, Giada Mantellato, Florian Kuester, Peter Schettina, Melanie Nelles, Jens Michael Seeger, Hamid Kashkar, Catherin Nieman. The anti-apoptotic Bcl-2 protein regulates hair follicle stem cell function. EMBO reports. vol 22. issue 10. 2021-10-22. PMID:34342114. |
in contrast, ectopic bcl-2 expression blocks apoptosis during hf regression, resulting in the accumulation of quiescent scs and delaying hf growth in mice. |
2021-10-22 |
2023-08-13 |
mouse |
| Li Cao, Jie Zhao, Li Ma, Jiawen Chen, Jingru Xu, Sajid Ur Rahman, Shibin Feng, Yu Li, Jinjie Wu, Xichun Wan. Lycopene attenuates zearalenone-induced oxidative damage of piglet sertoli cells through the nuclear factor erythroid-2 related factor 2 signaling pathway. Ecotoxicology and environmental safety. vol 225. 2021-10-05. PMID:34482067. |
zea downregulated the relative mrna and protein expression of bcl-2 in piglet scs, promoted cell apoptosis, and upregulated the relative mrna and protein expression of lc3, beclin-1, and bax. |
2021-10-05 |
2023-08-13 |
Not clear |
| Li Cao, Jie Zhao, Li Ma, Jiawen Chen, Jingru Xu, Sajid Ur Rahman, Shibin Feng, Yu Li, Jinjie Wu, Xichun Wan. Lycopene attenuates zearalenone-induced oxidative damage of piglet sertoli cells through the nuclear factor erythroid-2 related factor 2 signaling pathway. Ecotoxicology and environmental safety. vol 225. 2021-10-05. PMID:34482067. |
in conclusion, lyc alleviated the oxidative damage of scs caused by zea by promoting the expression of nrf2 pathway and decreased autophagy and apoptosis. |
2021-10-05 |
2023-08-13 |
Not clear |
| Xuejiao An, Taotao Li, Nana Chen, Huihui Wang, Xia Wang, Youji M. PGAM1 regulates the glycolytic metabolism of SCs in tibetan sheep and its influence on the development of SCs. Gene. vol 804. 2021-09-22. PMID:34418471. |
then the tibetan sheep primary sertoli cells (scs) were isolated to construct pgam1 gene overexpression and interference vectors, and to transfect primary scs so as to promote and inhibit pgam1 gene expression; cck-8 and flow cytometry were used to detect the proliferation effect of scs;qrt-pcr technology was employed to detect the changes in the expression of genes related to cell proliferation and apoptosis. |
2021-09-22 |
2023-08-13 |
Not clear |
| Xuejiao An, Taotao Li, Nana Chen, Huihui Wang, Xia Wang, Youji M. PGAM1 regulates the glycolytic metabolism of SCs in tibetan sheep and its influence on the development of SCs. Gene. vol 804. 2021-09-22. PMID:34418471. |
the pgam1 gene might regulate the glycolytic metabolism pathway and regulate the sperm formation and maturation process by affecting the proliferation and apoptosis of scs. |
2021-09-22 |
2023-08-13 |
Not clear |
| Shuangchan Wu, Sarrabeth Stone, Yuan Yue, Wensheng Li. Endoplasmic reticulum associated degradation is required for maintaining endoplasmic reticulum homeostasis and viability of mature Schwann cells in adults. Glia. vol 69. issue 2. 2021-07-28. PMID:32935902. |
interestingly, sel1l deficiency had no effect on actively myelinating scs during development, but led to later-onset mature sc apoptosis and demyelination in the adult pns. |
2021-07-28 |
2023-08-13 |
mouse |
| Shuangchan Wu, Sarrabeth Stone, Yuan Yue, Wensheng Li. Endoplasmic reticulum associated degradation is required for maintaining endoplasmic reticulum homeostasis and viability of mature Schwann cells in adults. Glia. vol 69. issue 2. 2021-07-28. PMID:32935902. |
moreover, inactivation of the pancreatic er kinase (perk) branch of the upr did not influence the viability and function of actively myelinating scs, but resulted in exacerbation of er stress and apoptosis of mature scs in sc-specific sel1l deficient mice. |
2021-07-28 |
2023-08-13 |
mouse |
| Bohan Li, Xiao Wan. Photobiomodulation enhances facial nerve regeneration via activation of PI3K/Akt signaling pathway-mediated antioxidant response. Lasers in medical science. 2021-07-24. PMID:34302577. |
the results showed that photobiomodulation improved axonal regeneration and functional recovery, and also promoted proliferation, and inhibited apoptosis of scs, both of these were considered as the most effective parameters in 250mw group. |
2021-07-24 |
2023-08-13 |
rat |
| Jing Li, Bo-Xing Sun, Da-Li Wang, Ying Liu, Jia-Jia Qi, Xiao-Wei Nie, Chun-Yan Bai, Jia-Bao Zhang, Shuang Lian. Melatonin ameliorates cypermethrin-induced impairments by regulating oxidative stress, DNA damage and apoptosis in porcine Sertoli cells. Theriogenology. vol 167. 2021-06-21. PMID:33774368. |
mechanistic investigations revealed that cyp induced oxidative stress and dna damage in porcine scs, which provoked mitochondria-associated apoptosis. |
2021-06-21 |
2023-08-13 |
Not clear |
| Jing Li, Bo-Xing Sun, Da-Li Wang, Ying Liu, Jia-Jia Qi, Xiao-Wei Nie, Chun-Yan Bai, Jia-Bao Zhang, Shuang Lian. Melatonin ameliorates cypermethrin-induced impairments by regulating oxidative stress, DNA damage and apoptosis in porcine Sertoli cells. Theriogenology. vol 167. 2021-06-21. PMID:33774368. |
overall, our results reveal that the mechanism underlying cyp-induced toxicity in porcine scs involves oxidative stress, dna damage, and apoptosis and suggest that melatonin may be used as a highly effective protective agent against oxidative stress. |
2021-06-21 |
2023-08-13 |
Not clear |
| Liu Yang, Huan Cao, Dong Sun, Bin Hou, Ling Lin, Zhong-Yang Shen, Hong-Li Son. Bone marrow mesenchymal stem cells combine with normothermic machine perfusion to improve rat donor liver quality-the important role of hepatic microcirculation in donation after circulatory death. Cell and tissue research. vol 381. issue 2. 2021-06-17. PMID:32347385. |
compared with scs, p and bp significantly improved liver function and liver histological damage, reduced hepatocyte apoptosis, and repaired hepatocyte mitochondrial damage after 6 h in vitro. |
2021-06-17 |
2023-08-13 |
rat |
| Jingfei Zhong, Jiaming Zhou, Hui Sun, Yinping Wu, Ye Wu, Meiyuan L. Effects of Salvia miltiorrhiza injection on apoptosis of Schwann cells induced by hydrogen peroxide. Annals of palliative medicine. vol 10. issue 1. 2021-05-14. PMID:33545791. |
in the present study, we investigated the effects of salvia miltiorrhiza injection in protecting schwann cells (scs) from hydrogen peroxide (h2o2)-induced cell apoptosis. |
2021-05-14 |
2023-08-13 |
Not clear |
| Liu Yang, Huan Cao, Dong Sun, Ling Lin, Wei-Ping Zheng, Zhong-Yang Shen, Hong-Li Son. Normothermic Machine Perfusion Combined with Bone Marrow Mesenchymal Stem Cells Improves the Oxidative Stress Response and Mitochondrial Function in Rat Donation After Circulatory Death Livers. Stem cells and development. vol 29. issue 13. 2021-04-16. PMID:32253985. |
compared with scs group, after 6 h in vitro, the pb and p groups had significantly improved liver function and liver histological damage, reduced hepatocyte apoptosis and oxidative stress, improved hepatocyte mitochondrial damage, and increased mitochondrial membrane potential. |
2021-04-16 |
2023-08-13 |
rat |
| Thomas Prudhomme, Karine Renaudin, Maria Letizia Lo Faro, Diego Cantarovich, Delphine Kervella, David Minault, Jérémy Hervouet, Stéphanie Le Bas-Bernardet, Georges Karam, Gilles Blancho, Julien Brancherea. Ex situ hypothermic perfusion of nonhuman primate pancreas: A feasibility study. Artificial organs. vol 44. issue 7. 2021-04-12. PMID:31995645. |
at 25 mm hg pp, focal congestion of islets appeared after 12-h. immunostaining for insulin, glucagon, and somatostatin was normal and similar in controls and perfused pancreas transplants even after 24-h. apoptosis index represented by cleaved caspase 3 activity, was less than 1% in perfusion and control groups, even after 24-h. hp of nonhuman primate pancreas is feasible and not deleterious as far as 24-h compared to scs. |
2021-04-12 |
2023-08-13 |
Not clear |
| Zhi-Wen Song, Cheng-Long Jin, Mao Ye, Chun-Qi Gao, Hui-Chao Yan, Xiu-Qi Wan. Lysine inhibits apoptosis in satellite cells to govern skeletal muscle growth via the JAK2-STAT3 pathway. Food & function. vol 11. issue 5. 2021-03-23. PMID:32338270. |
in addition, the results showed that lys deficiency-induced apoptosis in satellite cells (scs) was mediated by the jak2-stat3 pathway inhibition. |
2021-03-23 |
2023-08-13 |
Not clear |
| Zhi-Wen Song, Cheng-Long Jin, Mao Ye, Chun-Qi Gao, Hui-Chao Yan, Xiu-Qi Wan. Lysine inhibits apoptosis in satellite cells to govern skeletal muscle growth via the JAK2-STAT3 pathway. Food & function. vol 11. issue 5. 2021-03-23. PMID:32338270. |
in conclusion, we found that lys inhibits apoptosis in scs to govern skeletal muscle growth via the jak2-stat3 pathway. |
2021-03-23 |
2023-08-13 |
Not clear |
| Liangyue Lu, Qian Zhang, Man Ren, Erhui Jin, Qianqian Hu, Chunfang Zhao, Shenghe L. Effects of Boron on Cytotoxicity, Apoptosis, and Cell Cycle of Cultured Rat Sertoli Cells In vitro. Biological trace element research. vol 196. issue 1. 2021-03-15. PMID:31656015. |
the present study aimed to investigate the effects of the administration of boron on viability, apoptosis, and cell cycle of primary rat sertoli cells (scs) in vitro. |
2021-03-15 |
2023-08-13 |
rat |
| Liangyue Lu, Qian Zhang, Man Ren, Erhui Jin, Qianqian Hu, Chunfang Zhao, Shenghe L. Effects of Boron on Cytotoxicity, Apoptosis, and Cell Cycle of Cultured Rat Sertoli Cells In vitro. Biological trace element research. vol 196. issue 1. 2021-03-15. PMID:31656015. |
cell apoptosis and cycle of scs were analyzed using flow cytometry. |
2021-03-15 |
2023-08-13 |
rat |
| Hossein Kargar Jahromi, Ali Farzin, Elham Hasanzadeh, Somayeh Ebrahimi Barough, Narges Mahmoodi, Mohammad Reza H Najafabadi, Morteza Sagharjoghi Farahani, Korosh Mansoori, Sadegh Shirian, Jafar A. Enhanced sciatic nerve regeneration by poly-L-lactic acid/multi-wall carbon nanotube neural guidance conduit containing Schwann cells and curcumin encapsulated chitosan nanoparticles in rat. Materials science & engineering. C, Materials for biological applications. vol 109. 2020-12-24. PMID:32228906. |
scs play an important role in the regeneration of injured peripheral nerve and controlled curcumin release can decrease scs apoptosis, and enhance the regeneration and functional recovery of injured peripheral nerves. |
2020-12-24 |
2023-08-13 |
rat |
| Silvia Magalhães-Novais, Juan C Bermejo-Millo, Rute Loureiro, Katia A Mesquita, M Rosário Domingues, Elisabete Maciel, Tânia Melo, Inês Baldeiras, Jenna R Erickson, Jon Holy, Yaiza Potes, Ana Coto-Montes, Paulo J Oliveira, Ignacio Vega-Nared. Cell quality control mechanisms maintain stemness and differentiation potential of P19 embryonic carcinoma cells. Autophagy. vol 16. issue 2. 2020-11-23. PMID:30990357. |
in addition, p19scs pluripotency was correlated with stronger antioxidant protection, modulation of apoptosis, and activation of macroautophagy, which all contributed to preserve scs quality by increasing the threshold for cell death activation. |
2020-11-23 |
2023-08-13 |
Not clear |