| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Natalia A Vilchinskaya, Sergey V Rozhkov, Olga V Turtikova, Timur M Mirzoev, Boris S Shenkma. AMPK Phosphorylation Impacts Apoptosis in Differentiating Myoblasts Isolated from Atrophied Rat Soleus Muscle. Cells. vol 12. issue 6. 2023-03-29. PMID:36980261. |
muscle atrophy appears to result in reduced number of scs due to apoptosis. |
2023-03-29 |
2023-08-14 |
rat |
| Ji Chen, Gengzhang Li, Xinxin Liu, Kemin Chen, Yuxia Wang, Jie Qin, Fengrui Yan. Delivery of miR-130a-3p Through Adipose-Derived Stem Cell-Secreted EVs Protects Against Diabetic Peripheral Neuropathy via DNMT1/NRF2/HIF1α/ACTA1 Axis. Molecular neurobiology. 2023-03-18. PMID:36933145. |
mir-130a-3p could be delivered to scs through adsc-derived evs to inhibit sc apoptosis and promote proliferation under a high-glucose environment. |
2023-03-18 |
2023-08-14 |
rat |
| Takashi Hasebe, Kenta Fujimoto, Atsuko Ishizuya-Ok. Stem cell development involves divergent thyroid hormone receptor subtype expression and epigenetic modifications in the amphibian intestine during metamorphosis. Vitamins and hormones. vol 122. 2023-03-02. PMID:36863790. |
in the amphibian intestine during metamorphosis, most of the larval epithelial cells undergo apoptosis, while a small number of the epithelial cells dedifferentiate into stem cells (scs). |
2023-03-02 |
2023-08-14 |
xenopus_laevis |
| Huihui Gao, Heran Cao, Zhenpeng Li, Long Li, Yingjie Guo, Yining Chen, Guofan Peng, Wenxian Zeng, Jian Du, Wuzi Dong, Fangxia Yan. Exosome-derived Small RNAs in mouse Sertoli cells inhibit spermatogonial apoptosis. Theriogenology. vol 200. 2023-02-22. PMID:36806925. |
we found that the exosomes derived from mouse scs inhibited the apoptosis of primary spermatogonia. |
2023-02-22 |
2023-08-14 |
mouse |
| Shenglei Feng, Hui Wen, Kuan Liu, Mengneng Xiong, Jinmei Li, Yiqian Gui, Chunyu Lv, Jin Zhang, Xixiang Ma, Xiaoli Wang, Shuiqiao Yua. hnRNPH1 establishes Sertoli-germ cell crosstalk through cooperation with PTBP1 and AR, and is essential for male fertility in mice. Development (Cambridge, England). vol 150. issue 3. 2023-01-31. PMID:36718792. |
conditional knockout of hnrnph1 in mouse scs leads to compromised blood-testis barrier function, delayed meiotic progression, increased germ cell apoptosis, sloughing of germ cells and, eventually, infertility of mice. |
2023-01-31 |
2023-08-14 |
mouse |
| Qiufeng Wu, Jiangtao Xie, Xiaoli Zhu, Juan H. Runt-related transcription factor 3, mediated by DNA-methyltransferase 1, regulated Schwann cell proliferation and myelination during peripheral nerve regeneration via JAK/STAT signaling pathway. Neuroscience research. 2023-01-23. PMID:36690210. |
runx3 knockdown notably suppressed the proliferation and migration, and induced the cell apoptosis of scs. |
2023-01-23 |
2023-08-14 |
rat |
| Shuhui Cao, Yue Wang, Yan Zhou, Yao Zhang, Xuxinyi Ling, Lincheng Zhang, Jingwen Li, Yu Yang, Weimin Wang, Michael R Shurin, Hua Zhon. A Novel Therapeutic Target for Small-Cell Lung Cancer: Tumor-Associated Repair-like Schwann Cells. Cancers. vol 14. issue 24. 2022-12-23. PMID:36551618. |
to clarify this issue, the cell proliferation assay, the annexin v apoptosis assay, and the transwell migration and invasion assay were conducted to elucidate the roles in sclc of tumor-associated scs (ta-scs) in the proliferation, apoptosis, migration, and invasion of sclc cells in vitro, compared to control group. |
2022-12-23 |
2023-08-14 |
human |
| Xueru Wang, Gang Xu, Hanyu Liu, Zhengtao Chen, Susu Huang, Jiushu Yuan, Chunguang Xie, Lian D. Inhibiting apoptosis of Schwann cell under the high-glucose condition: A promising approach to treat diabetic peripheral neuropathy using Chinese herbal medicine. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 157. 2022-12-03. PMID:36462309. |
inhibiting the apoptosis of scs through various pathological pathways in a high-glucose environment plays an important role in developing dpn. |
2022-12-03 |
2023-08-14 |
Not clear |
| Xueru Wang, Gang Xu, Hanyu Liu, Zhengtao Chen, Susu Huang, Jiushu Yuan, Chunguang Xie, Lian D. Inhibiting apoptosis of Schwann cell under the high-glucose condition: A promising approach to treat diabetic peripheral neuropathy using Chinese herbal medicine. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 157. 2022-12-03. PMID:36462309. |
therefore, inhibiting the apoptosis of scs can be a novel treatment strategy for dpn. |
2022-12-03 |
2023-08-14 |
Not clear |
| Xueru Wang, Gang Xu, Hanyu Liu, Zhengtao Chen, Susu Huang, Jiushu Yuan, Chunguang Xie, Lian D. Inhibiting apoptosis of Schwann cell under the high-glucose condition: A promising approach to treat diabetic peripheral neuropathy using Chinese herbal medicine. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 157. 2022-12-03. PMID:36462309. |
in this study, we have reviewed the effects of chm (both monomers and extracts) on the apoptosis of scs by interfering with the production of advanced glycation end products, oxidative stress, and endoplasmic reticulum stress pathological pathways. |
2022-12-03 |
2023-08-14 |
Not clear |
| Xueru Wang, Gang Xu, Hanyu Liu, Zhengtao Chen, Susu Huang, Jiushu Yuan, Chunguang Xie, Lian D. Inhibiting apoptosis of Schwann cell under the high-glucose condition: A promising approach to treat diabetic peripheral neuropathy using Chinese herbal medicine. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 157. 2022-12-03. PMID:36462309. |
this review will demonstrate the potentialities of chm in inhibiting apoptosis in scs, providing new insights and perspectives for treating dpn. |
2022-12-03 |
2023-08-14 |
Not clear |
| Edy Kornelius, Sing-Hua Tsou, Ching-Chi Chang, Ying-Jui Ho, Sheng-Chieh Lin, Wei-Liang Chen, Chien-Ning Huang, Chih-Li Li. Liraglutide Attenuates Glucolipotoxicity-Induced RSC96 Schwann Cells' Inflammation and Dysfunction. Biomolecules. vol 12. issue 10. 2022-10-27. PMID:36291547. |
our results showed that high glucose and high ffas reduced the viability of rsc96 scs by up to 51%, whereas liraglutide reduced oxidative stress by upregulating antioxidant enzymes, and thus protected cells from apoptosis. |
2022-10-27 |
2023-08-14 |
Not clear |
| Xiaoqin Xu, Dandan Luo, Qiuhui Xuan, Peng Lu, Chunxiao Yu, Qingbo Gua. Atlas of metabolism reveals palmitic acid results in mitochondrial dysfunction and cell apoptosis by inhibiting fatty acid β-oxidation in Sertoli cells. Frontiers in endocrinology. vol 13. 2022-10-14. PMID:36237186. |
moreover, pa treatment of scs significantly altered the lipidome, including significant decreases in cardiolipin and glycolipids as well as remarkable increases in ceramide and lysophospholipids, which indicated that mitochondrial function was affected and apoptosis was triggered. |
2022-10-14 |
2023-08-14 |
Not clear |
| Xiaoqin Xu, Dandan Luo, Qiuhui Xuan, Peng Lu, Chunxiao Yu, Qingbo Gua. Atlas of metabolism reveals palmitic acid results in mitochondrial dysfunction and cell apoptosis by inhibiting fatty acid β-oxidation in Sertoli cells. Frontiers in endocrinology. vol 13. 2022-10-14. PMID:36237186. |
the increased apoptosis rate of scs was verified by elevated protein expression levels of cleaved caspase-3 and bax as well as decreased bcl-2 protein expression level. |
2022-10-14 |
2023-08-14 |
Not clear |
| Xiaoqin Xu, Dandan Luo, Qiuhui Xuan, Peng Lu, Chunxiao Yu, Qingbo Gua. Atlas of metabolism reveals palmitic acid results in mitochondrial dysfunction and cell apoptosis by inhibiting fatty acid β-oxidation in Sertoli cells. Frontiers in endocrinology. vol 13. 2022-10-14. PMID:36237186. |
together, these findings indicated that pa may result in mitochondrial dysfunction and increased apoptosis by inhibiting fatty acid β-oxidation of scs. |
2022-10-14 |
2023-08-14 |
Not clear |
| Xianrong Xiong, Xingyu Min, Hailing Yu, Xixi Fei, Yanjin Zhu, Bangting Pan, Yan Xiong, Wei Fu, Jian L. MicroRNA-34b-5p targets PPP1R11 to inhibit proliferation and promote apoptosis in cattleyak Sertoli cells by regulating specific signaling pathways. Theriogenology. vol 194. 2022-10-09. PMID:36209544. |
overexpression of mir-34b-5p in scs suppressed proliferation and induced apoptosis, while the effects of mir-34b-5p knockdown were the reverse. |
2022-10-09 |
2023-08-14 |
Not clear |
| Xianrong Xiong, Xingyu Min, Hailing Yu, Xixi Fei, Yanjin Zhu, Bangting Pan, Yan Xiong, Wei Fu, Jian L. MicroRNA-34b-5p targets PPP1R11 to inhibit proliferation and promote apoptosis in cattleyak Sertoli cells by regulating specific signaling pathways. Theriogenology. vol 194. 2022-10-09. PMID:36209544. |
lastly, we confirmed that mir-34b-5p inhibited ppp1r11 expression and induced apoptosis by regulating proliferation- and apoptosis-related genes in scs. |
2022-10-09 |
2023-08-14 |
Not clear |
| Xianrong Xiong, Xingyu Min, Hailing Yu, Xixi Fei, Yanjin Zhu, Bangting Pan, Yan Xiong, Wei Fu, Jian L. MicroRNA-34b-5p targets PPP1R11 to inhibit proliferation and promote apoptosis in cattleyak Sertoli cells by regulating specific signaling pathways. Theriogenology. vol 194. 2022-10-09. PMID:36209544. |
thus, mir-34b-5p regulates the apoptosis and proliferation of cattleyak scs via targeting ppp1r11, which can provide an innovative direction for exploring the mechanism of cattleyak male sterility. |
2022-10-09 |
2023-08-14 |
Not clear |
| Mengqi Liu, Zhengkai Yue, Bin Zhang, Fan Li, Lei Liu, Fuchang L. mTORC1 Mediates the Processes of Lysine Regulating Satellite Cells Proliferation, Apoptosis, and Autophagy. Metabolites. vol 12. issue 9. 2022-09-23. PMID:36144192. |
the results show lys deprivation significantly decreases scs viability, protein synthesis, and cell cycling, increases autophagy and apoptosis, and inhibits the mtorc1 signaling pathway. |
2022-09-23 |
2023-08-14 |
Not clear |
| Mengqi Liu, Zhengkai Yue, Bin Zhang, Fan Li, Lei Liu, Fuchang L. mTORC1 Mediates the Processes of Lysine Regulating Satellite Cells Proliferation, Apoptosis, and Autophagy. Metabolites. vol 12. issue 9. 2022-09-23. PMID:36144192. |
mtorc1 signaling pathway activation during lys deprivation or mtorc1 signaling pathway inhibition during lys addition attenuates the effect of lys deprivation or addition on scs viability, protein synthesis, cell cycling, autophagy, and apoptosis. |
2022-09-23 |
2023-08-14 |
Not clear |