| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| MinBo Jiang, Yang Li, WenWen Fan, XiaoYan Shen, Kai Jiang, DeGuo Wan. Circ-KATNAL1 Knockdown Reduces Neuronal Apoptosis and Alleviates Spinal Cord Injury Through the miR-98-5p/PRDM5 Regulatory Axis. Molecular biotechnology. 2023-09-27. PMID:37758970. |
in addition to that, the pathological changes of spinal cord tissue, neuronal apoptosis, and inflammatory responses were correspondingly observed and analyzed. |
2023-09-27 |
2023-10-07 |
rat |
| MinBo Jiang, Yang Li, WenWen Fan, XiaoYan Shen, Kai Jiang, DeGuo Wan. Circ-KATNAL1 Knockdown Reduces Neuronal Apoptosis and Alleviates Spinal Cord Injury Through the miR-98-5p/PRDM5 Regulatory Axis. Molecular biotechnology. 2023-09-27. PMID:37758970. |
circ-katnal1 was up-regulated in the spinal cord tissue of sci rats, and circ-katnal1 knockdown could improve neural function, alleviate pathological changes of spinal cord tissue, and inhibit neuronal apoptosis and inflammatory responses in sci rats. |
2023-09-27 |
2023-10-07 |
rat |
| Hongxiang Hong, Guanhua Xu, Guofeng Bao, Jinlong Zhang, Chu Chen, Jiajia Chen, Chunshuai Wu, Jiawei Jiang, Jiayi Huang, Haiming Huang, Zhiming Cu. VIRMA promotes neuron apoptosis via inducing m6A methylation of STK10 in spinal cord injury animal models. CNS neuroscience & therapeutics. 2023-09-18. PMID:37721438. |
virma promotes neuron apoptosis via inducing m6a methylation of stk10 in spinal cord injury animal models. |
2023-09-18 |
2023-10-07 |
Not clear |
| Xiaobang Liu, Junpeng Sun, Jiaqun Du, Jinyu An, Yingqiao Li, Yu Hu, Ying Xiong, Yanan Yu, He Tian, Xifan Mei, Chao W. Encapsulation of Selenium Nanoparticles and Metformin in Macrophage-Derived Cell Membranes for the Treatment of Spinal Cord Injury. ACS biomaterials science & engineering. 2023-09-15. PMID:37713674. |
a series of pathological changes after spinal cord injury (sci) are usually associated with oxidative stress, inflammation, and apoptosis. |
2023-09-15 |
2023-10-07 |
mouse |
| Aihua Xu, Yang Yang, Yang Shao, Manyu Jiang, Yongxin Sun, Bo Fen. FHL2 regulates microglia M1/M2 polarization after spinal cord injury via PARP14-depended STAT1/6 pathway. International immunopharmacology. vol 124. issue Pt A. 2023-09-14. PMID:37708708. |
neuronal apoptosis and inflammation exacerbate the secondary injury after spinal cord injury (sci). |
2023-09-14 |
2023-10-07 |
mouse |
| Yi-Bo Xu, Yang Sun, Lin-Yu Xiao, Guo-Qing Zhu, Xue Song, Jian-Guo Hu, Qi Q. [Effect of Shionone on Neuron Apoptosis After Spinal Cord Injury in Mice]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. 2023-09-07. PMID:37674468. |
[effect of shionone on neuron apoptosis after spinal cord injury in mice]. |
2023-09-07 |
2023-10-07 |
mouse |
| Yi-Bo Xu, Yang Sun, Lin-Yu Xiao, Guo-Qing Zhu, Xue Song, Jian-Guo Hu, Qi Q. [Effect of Shionone on Neuron Apoptosis After Spinal Cord Injury in Mice]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. 2023-09-07. PMID:37674468. |
methods c57bl/6 mice were treated to induce the sci model and then assigned into a model group(sci group),a sci+shi group,and a sham surgery(control)group.the basso mouse scale(bms)score was determined to evaluate the recovery of motor function in sci mice.hematoxylin-eosin(he)staining,nissl staining,and immunofluorescence staining were employed to examine the fibrosis,morphological changes of neurons,and neuron apoptosis in the spinal cord tissue of sci mice,respectively.the mouse hippocampal neuronal cell line ht22 was cultured in vitro and then classified into tumor necrosis factor α(tnf-α)induction and shi groups.western blotting was employed to determine the expression of apoptosis-associated proteins.network pharmacology,gene ontology annotation,and kyoto encyclopedia of genes and genomes pathway enrichment were employed to predict the possible molecular targets and signaling pathways of shi in promoting functional recovery from sci.furthermore,the prediction results were verified by in vitro and in vivo experiments. |
2023-09-07 |
2023-10-07 |
mouse |
| Jianhua Hu, Kun Huang, Feilong Bao, Shixiao Zhong, Qianbo Fan, Weichao L. Low-dose lipopolysaccharide inhibits spinal cord injury-induced neuronal apoptosis by regulating autophagy through the lncRNA MALAT1/Nrf2 axis. PeerJ. vol 11. 2023-09-04. PMID:37663283. |
low-dose lipopolysaccharide inhibits spinal cord injury-induced neuronal apoptosis by regulating autophagy through the lncrna malat1/nrf2 axis. |
2023-09-04 |
2023-09-07 |
Not clear |
| Tianli Xu, Qiancheng Zhu, Qun Huang, Qi Gu, Yi Zhu, Mengjie Tang, Shoujin Tian, Liming Wang, Fei Yan, Jianfei Ge, Xiaolong Lin, Weiping Sh. FGF21 prevents neuronal cell ferroptosis after spinal cord injury by activating the FGFR1/β-Klotho pathway. Brain research bulletin. 2023-09-03. PMID:37660729. |
meanwhile, rhfgf21 decreased cell apoptosis following acute spinal cord damage. |
2023-09-03 |
2023-09-07 |
human |
| Shijie Lv, Kunchi Zhao, Ran Li, Chunyang Meng, Guangchun Li, Fei Yi. EGFR-Activated JAK2/STAT3 Pathway Confers Neuroprotection in Spinal Cord Ischemia-Reperfusion Injury: Evidence from High-Throughput Sequencing and Experimental Models. Molecular neurobiology. 2023-09-01. PMID:37656314. |
in vivo animal experiments further confirmed this conclusion, suggesting that egfr inhibits sci/r-induced neuronal apoptosis by activating the jak2/stat3 signaling pathway, thereby improving sci/r-induced spinal cord injury in mice. |
2023-09-01 |
2023-09-07 |
mouse |
| Lan Luo, Yuqing Wang, Jiaqi Tong, Lu Li, Yanbing Zhu, Mu Ji. Xenon postconditioning attenuates neuronal injury after spinal cord ischemia/reperfusion injury by targeting endoplasmic reticulum stress-associated apoptosis. Neurosurgical review. vol 46. issue 1. 2023-08-29. PMID:37644159. |
xenon postconditioning attenuates neuronal injury after spinal cord ischemia/reperfusion injury by targeting endoplasmic reticulum stress-associated apoptosis. |
2023-08-29 |
2023-09-07 |
rat |
| Lan Luo, Yuqing Wang, Jiaqi Tong, Lu Li, Yanbing Zhu, Mu Ji. Xenon postconditioning attenuates neuronal injury after spinal cord ischemia/reperfusion injury by targeting endoplasmic reticulum stress-associated apoptosis. Neurosurgical review. vol 46. issue 1. 2023-08-29. PMID:37644159. |
xe postconditioning remarkably alleviated hind limb motor function, reduced neuronal apoptosis rate, increased the number of normal neurons, and inhibited the expression of er stress-related protein in spinal cord. |
2023-08-29 |
2023-09-07 |
rat |
| Hai-Hua Yao, You-Jiang Min, Dong-Ying Hong, Li Wang, Xiu-Yun Lu, Yi-Hua Yan. [Electroacupuncture improves limb motor function by down-regulating cytosolic phospholi-pase A2 and reducing apoptosis of nerve cells in rats with spinal cord injury]. Zhen ci yan jiu = Acupuncture research. vol 48. issue 8. 2023-08-24. PMID:37614136. |
[electroacupuncture improves limb motor function by down-regulating cytosolic phospholi-pase a2 and reducing apoptosis of nerve cells in rats with spinal cord injury]. |
2023-08-24 |
2023-09-07 |
rat |
| Hai-Hua Yao, You-Jiang Min, Dong-Ying Hong, Li Wang, Xiu-Yun Lu, Yi-Hua Yan. [Electroacupuncture improves limb motor function by down-regulating cytosolic phospholi-pase A2 and reducing apoptosis of nerve cells in rats with spinal cord injury]. Zhen ci yan jiu = Acupuncture research. vol 48. issue 8. 2023-08-24. PMID:37614136. |
to observe the effect of electroacupuncture（ea） on the expression of cytosolic phospholipase a2 （cpla2） and apoptosis of nerve cells in rats with spinal cord injury （sci）, so as to explore its mechanisms underlying improvement of sci. |
2023-08-24 |
2023-09-07 |
rat |
| Na Li, Lu Chen, Xiaoqing Zhao, Chi Gu, Yong Chang, Shiqing Fen. Targeting ANXA7/LAMP5-mTOR axis attenuates spinal cord injury by inhibiting neuronal apoptosis via enhancing autophagy in mice. Cell death discovery. vol 9. issue 1. 2023-08-24. PMID:37620352. |
targeting anxa7/lamp5-mtor axis attenuates spinal cord injury by inhibiting neuronal apoptosis via enhancing autophagy in mice. |
2023-08-24 |
2023-09-07 |
mouse |
| Wei Rong, Huimin Li, Huadong Yang, Bei Yuan, Jianjin Zhu, Jiuzheng Deng, Songhua Xiao, Cheng Zhan. Ezetimibe attenuates functional impairment via inhibition of oxidative stress and inflammation in traumatic spinal cord injury. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 6. 2023-08-22. PMID:37605573. |
sustained inflammation after a traumatic spinal cord injury (tsci) triggers oxidative stress and neuronal apoptosis, hindering functional recovery. |
2023-08-22 |
2023-09-07 |
mouse |
| Yaseen Awad-Igbaria, Nadine Ferreira, Ali Keadan, Reem Sakas, Doron Edelman, Alon Shamir, Jean Francous-Soustiel, Eilam Palzu. HBO treatment enhances motor function and modulates pain development after sciatic nerve injury via protection the mitochondrial function. Journal of translational medicine. vol 21. issue 1. 2023-08-15. PMID:37582750. |
peripheral nerve injury can cause neuroinflammation and neuromodulation that lead to mitochondrial dysfunction and neuronal apoptosis in the dorsal root ganglion (drg) and spinal cord, contributing to neuropathic pain and motor dysfunction. |
2023-08-15 |
2023-09-07 |
Not clear |
| Hong-Bo Yang, Ying Li, Xiu-Hai Li, Qing-Ming Yan, Xian-Zhang Han, Jian Cao, Hong-Peng Sang, Jin-Long L. The compensatory increase of GLIS3 inhibited neuronal apoptosis through regulating MOB1b: a possible strategy for the functional recovery after spinal cord injury. Experimental animals. 2023-08-13. PMID:37574269. |
the compensatory increase of glis3 inhibited neuronal apoptosis through regulating mob1b: a possible strategy for the functional recovery after spinal cord injury. |
2023-08-13 |
2023-08-16 |
mouse |
| Hong-Bo Yang, Ying Li, Xiu-Hai Li, Qing-Ming Yan, Xian-Zhang Han, Jian Cao, Hong-Peng Sang, Jin-Long L. The compensatory increase of GLIS3 inhibited neuronal apoptosis through regulating MOB1b: a possible strategy for the functional recovery after spinal cord injury. Experimental animals. 2023-08-13. PMID:37574269. |
spinal cord injury (sci) is a devastating disease characterized by neuronal apoptosis. |
2023-08-13 |
2023-08-16 |
mouse |
| Hong-Bo Yang, Ying Li, Xiu-Hai Li, Qing-Ming Yan, Xian-Zhang Han, Jian Cao, Hong-Peng Sang, Jin-Long L. The compensatory increase of GLIS3 inhibited neuronal apoptosis through regulating MOB1b: a possible strategy for the functional recovery after spinal cord injury. Experimental animals. 2023-08-13. PMID:37574269. |
the results showed that glis3 expression was significantly increased in spinal cord tissues of sci mice, and glis3 overexpression promoted the functional recovery, reserved histological changes, and inhibited neuronal apoptosis after sci. |
2023-08-13 |
2023-08-16 |
mouse |