| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ha Neui Kim, Madeline R McCrea, Shuxin L. Advances in molecular therapies for targeting pathophysiology in spinal cord injury. Expert opinion on therapeutic targets. 2023-04-05. PMID:37017093. |
the primary injury damages spinal cord tissues and secondary injury mechanisms, including ischemia, apoptosis, inflammation, and astrogliosis, further exacerbate the lesions to the spinal cord. |
2023-04-05 |
2023-08-14 |
Not clear |
| Wei Tang, Lu Liu, Yi Yan, Yongzhi Xi. Sodium houttuyfonate exerts its neuroprotection effect by inhibiting the M1 microglia polarization in a TLR4/NF-κB signal pathway. Brain research. 2023-04-03. PMID:37011720. |
the injured spinal cord exhibited less neuronal loss, cell apoptosis, and m1 microglial polarization after sh treatment. |
2023-04-03 |
2023-08-14 |
rat |
| Chengxuan Tang, Tianzhen Xu, Minghai Dai, Xiqiang Zhong, Guangjie Shen, Liangle Li. Sitagliptin attenuates neuronal apoptosis via inhibiting the endoplasmic reticulum stress after acute spinal cord injury. Human & experimental toxicology. vol 42. 2023-03-28. PMID:36977492. |
sitagliptin attenuates neuronal apoptosis via inhibiting the endoplasmic reticulum stress after acute spinal cord injury. |
2023-03-28 |
2023-08-14 |
rat |
| Chengxuan Tang, Tianzhen Xu, Minghai Dai, Xiqiang Zhong, Guangjie Shen, Liangle Li. Sitagliptin attenuates neuronal apoptosis via inhibiting the endoplasmic reticulum stress after acute spinal cord injury. Human & experimental toxicology. vol 42. 2023-03-28. PMID:36977492. |
regulation of endoplasmic reticulum stress (er) stress-induced apoptosis and nerve regeneration is a hopeful way for acute spinal cord injury (sci). |
2023-03-28 |
2023-08-14 |
rat |
| Hassan Reda Hassan Elsayed, Mohammed R Rabei, Mohamed Mahmoud Abdelraheem Elshaer, Eman Mohamad El Nashar, Mansour Abdullah Alghamdi, Zainah Al-Qahtani, Ahmed Nabaw. Suppression of neuronal apoptosis and glial activation with modulation of Nrf2/HO-1 and NF-kB signaling by curcumin in streptozotocin-induced diabetic spinal cord central neuropathy. Frontiers in neuroanatomy. vol 17. 2023-03-27. PMID:36968023. |
suppression of neuronal apoptosis and glial activation with modulation of nrf2/ho-1 and nf-kb signaling by curcumin in streptozotocin-induced diabetic spinal cord central neuropathy. |
2023-03-27 |
2023-08-14 |
rat |
| Hassan Reda Hassan Elsayed, Mohammed R Rabei, Mohamed Mahmoud Abdelraheem Elshaer, Eman Mohamad El Nashar, Mansour Abdullah Alghamdi, Zainah Al-Qahtani, Ahmed Nabaw. Suppression of neuronal apoptosis and glial activation with modulation of Nrf2/HO-1 and NF-kB signaling by curcumin in streptozotocin-induced diabetic spinal cord central neuropathy. Frontiers in neuroanatomy. vol 17. 2023-03-27. PMID:36968023. |
the spinal cord reacts to diabetes by neuronal apoptosis, microglial activation, and astrocytosis, with a disturbance in neuronal and glial nuclear factor erythroid 2-related factor/heme oxygenase-1 (nrf2/ho-1) and nuclear factor kappa-light-chain-enhancer of activated b cells (nf-kb) signaling. |
2023-03-27 |
2023-08-14 |
rat |
| Xin Li, Xuan-Kang Wang, Zhi-Jie Zhu, Zhuo-Wen Liang, Peng-Hui Li, Yang-Guang Ma, Tan Ding, Kun Li, Xiao-Shuang Zuo, Cheng Ju, Zhi-Hao Zhang, Zhi-Wen Song, Hui-Lin Quan, Jia-Wei Zhang, Liang Luo, Zhe Wang, Xue-Yu H. Photobiomodulation provides neuroprotection through regulating mitochondrial fission imbalance in the subacute phase of spinal cord injury. Neural regeneration research. vol 18. issue 9. 2023-03-17. PMID:36926726. |
these findings suggest that photobiomodulation targets neuronal mitochondria, alleviates mitochondrial fission imbalance-induced neuronal apoptosis, and thereby promotes the motor function recovery of rats with spinal cord injury. |
2023-03-17 |
2023-08-14 |
rat |
| Yang Liu, Hao Yu, Peng Yu, Peng Peng, Chao Li, Zhenyang Xiang, Dexiang Ba. Gelatin methacryloyl hydrogel scaffold loaded with activated Schwann cells attenuates apoptosis and promotes functional recovery following spinal cord injury. Experimental and therapeutic medicine. vol 25. issue 4. 2023-03-13. PMID:36911380. |
gelatin methacryloyl hydrogel scaffold loaded with activated schwann cells attenuates apoptosis and promotes functional recovery following spinal cord injury. |
2023-03-13 |
2023-08-14 |
rat |
| Bin Xi, Jieping Fu, Dengfeng Wan, Zhiping Xi. Ginsenoside Rg1 attenuation of neurogenesis disorder and neuronal apoptosis in the rat hippocampus after spinal cord injury may involve brain-derived neurotrophic factor/extracellular signal-regulated kinase signaling. Neuroreport. vol 34. issue 5. 2023-03-07. PMID:36881751. |
ginsenoside rg1 attenuation of neurogenesis disorder and neuronal apoptosis in the rat hippocampus after spinal cord injury may involve brain-derived neurotrophic factor/extracellular signal-regulated kinase signaling. |
2023-03-07 |
2023-08-14 |
rat |
| Sheng Fang, Hao Tang, Ming-Zhi Li, Jian-Jun Chu, Zong-Sheng Yin, Qi-Yu Ji. Identification of the CCL2 PI3K/Akt axis involved in autophagy and apoptosis after spinal cord injury. Metabolic brain disease. 2023-02-16. PMID:36795287. |
identification of the ccl2 pi3k/akt axis involved in autophagy and apoptosis after spinal cord injury. |
2023-02-16 |
2023-08-14 |
Not clear |
| Min Fei, Zheng Li, Yuanwu Cao, Chang Jiang, Haodong Lin, Zixian Che. MicroRNA-182 improves spinal cord injury in mice by modulating apoptosis and the inflammatory response via IKKβ/NF-κB. Laboratory investigation; a journal of technical methods and pathology. vol 101. issue 9. 2023-02-12. PMID:36775547. |
microrna-182 improves spinal cord injury in mice by modulating apoptosis and the inflammatory response via ikkβ/nf-κb. |
2023-02-12 |
2023-08-14 |
mouse |
| Min Fei, Zheng Li, Yuanwu Cao, Chang Jiang, Haodong Lin, Zixian Che. MicroRNA-182 improves spinal cord injury in mice by modulating apoptosis and the inflammatory response via IKKβ/NF-κB. Laboratory investigation; a journal of technical methods and pathology. vol 101. issue 9. 2023-02-12. PMID:36775547. |
it was also observed that mir-182 overexpression reduced apoptosis and attenuated the inflammatory response in spinal cord tissue, as evidenced by the reduction of tumor necrosis factor (tnf)-α, interleukin (il)-6, and il-1β, and the induction of il-10. |
2023-02-12 |
2023-08-14 |
mouse |
| Min Fei, Zheng Li, Yuanwu Cao, Chang Jiang, Haodong Lin, Zixian Che. MicroRNA-182 improves spinal cord injury in mice by modulating apoptosis and the inflammatory response via IKKβ/NF-κB. Laboratory investigation; a journal of technical methods and pathology. vol 101. issue 9. 2023-02-12. PMID:36775547. |
mir-182 overexpression reduces apoptosis and attenuates the inflammatory response in spinal cord tissues by blocking the ikkβ/nf-κb pathway. |
2023-02-12 |
2023-08-14 |
mouse |
| David Reigada, Rodrigo M Maza, Teresa Muñoz-Galdeano, María Asunción Barreda-Manso, Altea Soto, Dan Lindholm, Rosa Navarro-Ruíz, Manuel Nieto-Día. Overexpression of the X-Linked Inhibitor of Apoptosis Protein (XIAP) in Neurons Improves Cell Survival and the Functional Outcome after Traumatic Spinal Cord Injury. International journal of molecular sciences. vol 24. issue 3. 2023-02-11. PMID:36769152. |
overexpression of the x-linked inhibitor of apoptosis protein (xiap) in neurons improves cell survival and the functional outcome after traumatic spinal cord injury. |
2023-02-11 |
2023-08-14 |
mouse |
| David Reigada, Rodrigo M Maza, Teresa Muñoz-Galdeano, María Asunción Barreda-Manso, Altea Soto, Dan Lindholm, Rosa Navarro-Ruíz, Manuel Nieto-Día. Overexpression of the X-Linked Inhibitor of Apoptosis Protein (XIAP) in Neurons Improves Cell Survival and the Functional Outcome after Traumatic Spinal Cord Injury. International journal of molecular sciences. vol 24. issue 3. 2023-02-11. PMID:36769152. |
apoptosis affects neurons after spinal cord injury (sci) and is associated with increased caspase activity. |
2023-02-11 |
2023-08-14 |
mouse |
| Fangqian Wu, Ping Zhang, Guohui Zho. The involvement of EGR1 in neuron apoptosis in the in vitro model of spinal cord injury via BTG2 up-regulation. Neurological research. 2023-02-10. PMID:36759943. |
the involvement of egr1 in neuron apoptosis in the in vitro model of spinal cord injury via btg2 up-regulation. |
2023-02-10 |
2023-08-14 |
Not clear |
| Ai-Hua Xu, Yang Yang, Yang Shao, Man-Yu Jiang, Yong-Xin Su. Poly(ADP-ribose) polymerase family member 14 promotes functional recovery after spinal cord injury through regulating microglia M1/M2 polarization via STAT1/6 pathway. Neural regeneration research. vol 18. issue 8. 2023-02-08. PMID:36751810. |
we found that parp14 was up-regulated in the injured spinal cord and that lentivirus-mediated downregulation of parp14 aggravated functional impairment after injury, accompanied by obvious neuronal apoptosis, severe neuroinflammation, and slight bone loss. |
2023-02-08 |
2023-08-14 |
mouse |
| Weiguo Ding, Weixing Xu, Di Lu, Hongfeng Sheng, Xinwei Xu, Bin Xu, Aote Zhen. Inhibition of TERC inhibits neural apoptosis and inflammation in spinal cord injury through Akt activation and p-38 inhibition via the miR-34a-5p/XBP-1 axis. Open medicine (Warsaw, Poland). vol 18. issue 1. 2023-02-06. PMID:36742154. |
inhibition of terc inhibits neural apoptosis and inflammation in spinal cord injury through akt activation and p-38 inhibition via the mir-34a-5p/xbp-1 axis. |
2023-02-06 |
2023-08-14 |
rat |
| Kiran Kumar Soni, Jinsu Hwang, Mahesh Ramalingam, Choonghyo Kim, Byeong C Kim, Han-Seong Jeong, Sujeong Jan. Endoplasmic Reticulum Stress Causing Apoptosis in a Mouse Model of an Ischemic Spinal Cord Injury. International journal of molecular sciences. vol 24. issue 2. 2023-01-21. PMID:36674822. |
endoplasmic reticulum stress causing apoptosis in a mouse model of an ischemic spinal cord injury. |
2023-01-21 |
2023-08-14 |
mouse |
| Kiran Kumar Soni, Jinsu Hwang, Mahesh Ramalingam, Choonghyo Kim, Byeong C Kim, Han-Seong Jeong, Sujeong Jan. Endoplasmic Reticulum Stress Causing Apoptosis in a Mouse Model of an Ischemic Spinal Cord Injury. International journal of molecular sciences. vol 24. issue 2. 2023-01-21. PMID:36674822. |
a spinal cord injury (sci) is the devastating trauma associated with functional deterioration due to apoptosis. |
2023-01-21 |
2023-08-14 |
mouse |