| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jian Hao, Zhenhan Li, Li Xie, Bingbing Yu, Boyuan Ma, Yubiao Yang, Xuchen Ma, Bitao Wang, Xianhu Zho. Syringaresinol promotes the recovery of spinal cord injury by inhibiting neuron apoptosis via activating the ubiquitination factor E4B/AKT Serine/Threonine kinase signal pathway. Brain research. 2023-11-22. PMID:37992795. |
syringaresinol promotes the recovery of spinal cord injury by inhibiting neuron apoptosis via activating the ubiquitination factor e4b/akt serine/threonine kinase signal pathway. |
2023-11-22 |
2023-11-29 |
rat |
| Hongdi Zhao, Xiaoqin Zong, Long Li, Na Li, Chunlei Liu, Wanchao Zhang, Juan Li, Cheng Yang, Siqin Huan. Electroacupuncture Inhibits Neuroinflammation Induced by Astrocytic Necroptosis Through RIP1/MLKL/TLR4 Pathway in a Mouse Model of Spinal Cord Injury. Molecular neurobiology. 2023-11-20. PMID:37982922. |
electroacupuncture (ea), an effective therapeutic efficacy against spinal cord injury (sci), has been proved to reduce neuronal cell apoptosis, inhibit inflammation, and prompt neural stem cell proliferation and differentiations. |
2023-11-20 |
2023-11-29 |
mouse |
| Xiaodan Mi, Chengtao Ni, Jingting Zhao, Nashwa Amin, Dian Jiao, Marong Fang, Xiangming Y. P2Y12 receptor mediates apoptosis and demyelination to affect functional recovery in mice with spinal cord injury. Neurochemistry international. 2023-11-12. PMID:37952830. |
p2y12 receptor mediates apoptosis and demyelination to affect functional recovery in mice with spinal cord injury. |
2023-11-12 |
2023-11-20 |
mouse |
| Xiaodan Mi, Chengtao Ni, Jingting Zhao, Nashwa Amin, Dian Jiao, Marong Fang, Xiangming Y. P2Y12 receptor mediates apoptosis and demyelination to affect functional recovery in mice with spinal cord injury. Neurochemistry international. 2023-11-12. PMID:37952830. |
it has been proven that p2y g protein-coupled purinergic receptors have a neuroprotective role in apoptosis and regeneration inside the damaged spinal cord. |
2023-11-12 |
2023-11-20 |
mouse |
| R Holota, V Dečmanová, A Alexovič Matiašová, J Košuth, L Slovinská, L Pačut, Z Tomori, Z Daxnerová, J Šev. Cleaved caspase-3 is present in the majority of glial cells in the intact rat spinal cord during postnatal life. Histochemistry and cell biology. 2023-11-08. PMID:37938347. |
despite the availability of a wide range of commercially produced antibodies against various apoptotic markers, data regarding apoptosis in intact spinal cord during postnatal development and adulthood are mostly missing. |
2023-11-08 |
2023-11-20 |
rat |
| R Holota, V Dečmanová, A Alexovič Matiašová, J Košuth, L Slovinská, L Pačut, Z Tomori, Z Daxnerová, J Šev. Cleaved caspase-3 is present in the majority of glial cells in the intact rat spinal cord during postnatal life. Histochemistry and cell biology. 2023-11-08. PMID:37938347. |
we investigated apoptosis in rat spinal cord at different stages of ontogenesis (postnatal days 8, 29, and 90). |
2023-11-08 |
2023-11-20 |
rat |
| Stephanie Sánchez-Torres, Carlos Orozco-Barrios, Hermelinda Salgado-Ceballos, Julia J Segura-Uribe, Christian Guerra-Araiza, Ángel León-Cholula, Julio Morán, Angélica Coyoy-Salgad. Tibolone Improves Locomotor Function in a Rat Model of Spinal Cord Injury by Modulating Apoptosis and Autophagy. International journal of molecular sciences. vol 24. issue 20. 2023-10-30. PMID:37894971. |
tibolone improves locomotor function in a rat model of spinal cord injury by modulating apoptosis and autophagy. |
2023-10-30 |
2023-11-08 |
rat |
| Hayder Jaffer, Syed Suhail Andrabi, Marianne Petro, Youzhi Kuang, Michael P Steinmetz, Vinod Labhasetwa. Catalytic antioxidant nanoparticles mitigate secondary injury progression and promote functional recovery in spinal cord injury model. Journal of controlled release : official journal of the Controlled Release Society. 2023-10-22. PMID:37866402. |
this led to reduced spinal cord tissue inflammation, apoptosis, cavitation, and inhibition of syringomyelia. |
2023-10-22 |
2023-11-08 |
rat |
| Filippo Mandelli, Yuancheng Zhang, Corina Nüesch, Hannah Ewald, Soheila Aghlmandi, Florian Halbeisen, Stefan Schären, Annegret Mündermann, Cordula Netze. Gait function assessed using 3D gait analysis in patients with cervical spinal myelopathy before and after surgical decompression: a systematic review and meta-analysis. The spine journal : official journal of the North American Spine Society. 2023-10-22. PMID:37866484. |
the compression of the spinal cord can lead to ischemia, inflammation, and neuronal apoptosis with a consequent impairment of the neurological function. |
2023-10-22 |
2023-11-08 |
Not clear |
| Guibin Zhong, Yanqiu Yang, Daming Feng, Ke Wei, Junling Chen, Jianwei Chen, Chao Den. Melatonin protects injured spinal cord neurons from apoptosis by inhibiting mitochondrial damage via the SIRT1/Drp1 signaling pathway. Neuroscience. 2023-10-21. PMID:37865165. |
melatonin protects injured spinal cord neurons from apoptosis by inhibiting mitochondrial damage via the sirt1/drp1 signaling pathway. |
2023-10-21 |
2023-11-08 |
mouse |
| Kai Gao, Wenbo Shao, Tian Wei, Zihan Yan, Nianhu Li, Chaoliang L. Wnt-3a improves functional recovery after spinal cord injury by regulating the inflammatory and apoptotic response in rats via wnt/β-catenin signaling pathway. Brain research. 2023-10-20. PMID:37858855. |
in our study, we evaluated the recovery of motor function after sci by bbb, observed neuronal apoptosis by western blot and tunel, observed the changes of neuronal inflammation by western blot and immunofluorescence staining, and observed the changes of motoneurons and spinal cord area in the anterior horn of the spinal cord via nissl and he staining. |
2023-10-20 |
2023-11-08 |
rat |
| Kai Gao, Wenbo Shao, Tian Wei, Zihan Yan, Nianhu Li, Chaoliang L. Wnt-3a improves functional recovery after spinal cord injury by regulating the inflammatory and apoptotic response in rats via wnt/β-catenin signaling pathway. Brain research. 2023-10-20. PMID:37858855. |
we found that wnt-3a could significantly promote the recovery of motor function, reduce the loss of motor neurons in the anterior horn of the spinal cord, promote the recovery of injured spinal cord tissue, inhibit neuronal apoptosis and inflammatory response, and ultimately promote neuronal function after sci. |
2023-10-20 |
2023-11-08 |
rat |
| Yuanlong Li, Hua Fan, Xiong Han, Jun Sun, Ming Ni, Xiaodan Hou, Fengqin Fang, Wei Zhang, Peizhi M. Long Non-Coding RNA MALAT1 Protects Against Spinal Cord Injury via Suppressing microRNA-125b-5p Mediated Microglial M1 Polarization, Neuroinflammation, and Neural Apoptosis. Molecular neurobiology. 2023-10-19. PMID:37858031. |
long non-coding rna malat1 protects against spinal cord injury via suppressing microrna-125b-5p mediated microglial m1 polarization, neuroinflammation, and neural apoptosis. |
2023-10-19 |
2023-11-08 |
rat |
| Yuanlong Li, Hua Fan, Xiong Han, Jun Sun, Ming Ni, Xiaodan Hou, Fengqin Fang, Wei Zhang, Peizhi M. Long Non-Coding RNA MALAT1 Protects Against Spinal Cord Injury via Suppressing microRNA-125b-5p Mediated Microglial M1 Polarization, Neuroinflammation, and Neural Apoptosis. Molecular neurobiology. 2023-10-19. PMID:37858031. |
this study aimed to further explore the relationship between lncrna malat1 and mir-125b-5p, as well as their effect on microglial activation, neuroinflammation, and neural apoptosis in spinal cord injury (sci). primary microglia from sprague dawley rats were stimulated with lipopolysaccharide (lps). |
2023-10-19 |
2023-11-08 |
rat |
| Zhijing Zhou, Peng Zhan. Formononetin ameliorates the LPS-induced inflammatory response and apoptosis of neuronal cells via NF-κB/NLRP3 signaling pathway. Functional & integrative genomics. vol 23. issue 4. 2023-10-17. PMID:37847432. |
the objective of this study was to investigate the impact of formononetin on cellular apoptosis and inflammatory responses following spinal cord injury (sci), as well as the underlying mechanisms involved. |
2023-10-17 |
2023-11-08 |
Not clear |
| Satoshi Nomura, Hiroyuki Katoh, Sho Yanagisawa, Toshihiro Noguchi, Keiko Okada, Masahiko Watanab. Administration of the GLP-1 receptor agonist exenatide in rats improves functional recovery after spinal cord injury by reducing endoplasmic reticulum stress. IBRO neuroscience reports. vol 15. 2023-10-12. PMID:37822517. |
after spinal cord injury (sci), endoplasmic reticulum (er) stress has been reported to be an integral part of the secondary injury process that causes apoptosis of glial cells, leading to remyelination failure. |
2023-10-12 |
2023-10-15 |
rat |
| Yi Luo, You-Zhi He, Yong-Fu Wang, Yu-Xia Xu, Li Yan. Adipose-derived mesenchymal stem cell exosomes ameliorate spinal cord injury in rats by activating the Nrf2/HO-1 pathway and regulating microglial polarization. Folia neuropathologica. vol 61. issue 3. 2023-10-11. PMID:37818693. |
motor function recovery was assessed on days 0, 7, 14, 21, and 28; histopathological changes and apoptosis levels in spinal cord tissues were observed by he staining and tunel staining; the levels of inflammatory cytokines tnf-a, il-6, and mcp-1 in spinal cord tissues were measured by elisa; the expression levels of inos, il-12, arg1, and mrc1 in spinal cord tissues were detected by qrt-pcr; and nrf2, ho-1, and nqo1 protein expression in spinal cord tissues were detected by western blot. |
2023-10-11 |
2023-10-15 |
rat |
| Zhiwei Jia, Tianlin Wen, Yuning Zhan. Possible mechanisms of treatment for spinal cord injury repair with tanshinone IIA. Frontiers in molecular neuroscience. vol 16. 2023-10-09. PMID:37808475. |
based on previous research, we believe that tanshinone iia promotes the survival and repair of nerves after spinal cord injury through its pharmacological effects such as anti-inflammatory, antioxidant, and prevention of cellular apoptosis in the spinal cord. |
2023-10-09 |
2023-10-15 |
Not clear |
| Jun-Yan Zhang, Z Du Steven, Ke-Hua Lia. Therapeutic effect of umbilical cord blood cells on spinal cord injury. Ibrain. vol 9. issue 2. 2023-10-03. PMID:37786552. |
spinal cord injury (sci) is a nervous system disease characterized by sensory and motor dysfunction, axonal apoptosis, decreased vascular density, and inflammation. |
2023-10-03 |
2023-10-07 |
Not clear |
| MinBo Jiang, Yang Li, WenWen Fan, XiaoYan Shen, Kai Jiang, DeGuo Wan. Circ-KATNAL1 Knockdown Reduces Neuronal Apoptosis and Alleviates Spinal Cord Injury Through the miR-98-5p/PRDM5 Regulatory Axis. Molecular biotechnology. 2023-09-27. PMID:37758970. |
circ-katnal1 knockdown reduces neuronal apoptosis and alleviates spinal cord injury through the mir-98-5p/prdm5 regulatory axis. |
2023-09-27 |
2023-10-07 |
rat |