| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sousan Cheong, Yujie Peng, Feng Lu, Yunfan H. Structural extracellular matrix-mediated molecular signaling in wound repair and tissue regeneration. Biochimie. 2024-10-06. PMID:39369941. |
through interactions with cells, matrix proteins regulate critical processes such as cell proliferation and differentiation, migration, and apoptosis, essential for maintaining tissue homeostasis, formation, and regeneration. |
2024-10-06 |
2024-10-09 |
Not clear |
| Yeheng Huang, Jing Sun, Sunlong Li, Yifeng Shi, Lianggao Yu, Aimin Wu, Xiangyang Wan. Isoliquiritigenin mitigates intervertebral disc degeneration induced by oxidative stress and mitochondrial impairment through a PPARγ-dependent pathway. Free radical biology & medicine. 2024-10-04. PMID:39366471. |
oxidative stress, mitochondrial dysfunction, and apoptosis play significant roles in the degradation of extracellular matrix (ecm) in nucleus pulposus cells (npcs), ultimately contributing to intervertebral disc degeneration (ivdd). |
2024-10-04 |
2024-10-07 |
Not clear |
| Roderick J Tan, Youhua Li. Matrix metalloproteinases in kidney homeostasis and diseases: an update. American journal of physiology. Renal physiology. 2024-10-03. PMID:39361724. |
while capable of collectively degrading each component of the extracellular matrix, mmps also degrade nonmatrix substrates to regulate inflammation, epithelial plasticity, proliferation, apoptosis, and angiogenesis. |
2024-10-03 |
2024-10-07 |
Not clear |
| Yufan Zhu, Xu Liu, Xihang Chen, Yunjun Lia. Adipose-derived stem cells apoptosis rejuvenate radiation-impaired skin in mice via remodeling and rearranging dermal collagens matrix. Stem cell research & therapy. vol 15. issue 1. 2024-09-28. PMID:39334464. |
adipose-derived stem cells apoptosis rejuvenate radiation-impaired skin in mice via remodeling and rearranging dermal collagens matrix. |
2024-09-28 |
2024-10-01 |
mouse |
| Jiena Liu, Hao Wu, Qin Wang, Shengye Jin, Siyu Hou, Zibo Shen, Liuying Zhao, Shouping Xu, Da Pan. Identification of Novel Anoikis-Related Gene Signatures to Predict the Prognosis, Immune Microenvironment, and Drug Sensitivity of Breast Cancer Patients. Cancer control : journal of the Moffitt Cancer Center. vol 31. 2024-09-28. PMID:39340434. |
anoikis, a specific type of apoptosis that is triggered by the loss of anchoring between cells and the native extracellular matrix, plays a vital role in cancer invasion and metastasis. |
2024-09-28 |
2024-10-01 |
Not clear |
| Yuanrui Wang, Xiaochao Chen, Yongfeng Chen, Qiang Sun, Huayi Wan. Regulatory effect and mechanism of CircSEC24A in IL-1β-induced osteoarthritis. Archives of physiology and biochemistry. 2024-09-27. PMID:39328069. |
the absence of circsec24a overturned il-1β-induced suppression of cell viability and promotion of oxidative stress, apoptosis, extracellular matrix (ecm) degradation, and inflammation in chon-001 cells. |
2024-09-27 |
2024-09-29 |
Not clear |
| Xibang Zhao, Zhaoji Cai, Ying Luo, Zhousheng Lin, Jiali Wan. Overexpression of CGRP receptor attenuates tendon graft degeneration in anterior cruciate ligament reconstruction. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2024-09-25. PMID:39318262. |
cell apoptosis or necrosis, extracellular matrix loss, and excessive inflammation may induce tendon graft degeneration. |
2024-09-25 |
2024-09-27 |
mouse |
| Yuxiao Zhang, E Liu, Hongjin Gao, Qingying He, Anjing Chen, Yaobing Pang, Xueer Zhang, Sixian Bai, Jinhao Zeng, Jing Gu. Natural products for the treatment of hypertrophic scars: Preclinical and clinical studies. Heliyon. vol 10. issue 17. 2024-09-19. PMID:39296083. |
generally speaking, natural products inhibit inflammation, myofibroblast activation, angiogenesis, and collagen accumulation by targeting interleukins, tumor necrosis factor-α, vascular endothelial growth factors, platelet-derived growth factors, and matrix metalloproteinases, so as to play an anti-hs effects of natural products are attributed to their anti-inflammatory, anti-proliferative, anti-angiogenesis, and pro-apoptotic (enhancing apoptosis and autophagy) roles, thus treating hs. |
2024-09-19 |
2024-09-21 |
Not clear |
| Xinyu Zhao, Huirong Huang, Xinyu Jiang, Shimin Zheng, Chenyu Qiu, Yingfeng Cheng, Yinhao Lin, Yunzhi Wang, Yuqi Yan, Xinyu Di, Miyun Hu, Wanling Zhu, Fugen Wu, Xianbao Shi, Ruijie Chen, Longfa Ko. Supramolecular nanoparticle loaded with bilirubin enhances cartilage protection and alleviates osteoarthritis via modulating oxidative stress and inflammatory responses. Colloids and surfaces. B, Biointerfaces. vol 245. 2024-09-17. PMID:39288548. |
prolonged chondrocyte oxidative stress contributes to the development of diseases, including chondrocyte apoptosis, cartilage matrix degradation, and aggravation of articular cartilage damage. |
2024-09-17 |
2024-09-20 |
rat |
| Heng Yu, Jinghao Liang, Yingying Bao, Kaiye Chen, Yangcan Jin, Xiang Li, Hao Chen, Yong Gou, Keyu Lu, Zhongke Li. Ginkgolide A enhances FoxO1 expression and reduces endoplasmic reticulum stress to mitigate osteoarthritis in mice. International immunopharmacology. vol 142. issue Pt B. 2024-09-17. PMID:39288630. |
further exploration into the effects on endoplasmic reticulum stress (ers), apoptosis, extracellular matrix (ecm) degradation, and forkhead box o1 (foxo1) related pathways was conducted using western blotting, immunofluorescence, tunel staining, flow cytometry, x-ray, micro-computed tomography (micro-ct) analysis, and histological staining. |
2024-09-17 |
2024-09-20 |
mouse |
| Lin Cheng, Yuhang Zhang, Man Lv, Wei Huang, Kunyu Zhang, Ziqiao Guan, Xirui Feng, Yanmei Yang, Yanhui Gao, Xiaona Li. Impaired learning and memory in male mice induced by sodium arsenite was associated with MMP-2/MMP-9-mediated blood-brain barrier disruption and neuronal apoptosis. Ecotoxicology and environmental safety. vol 285. 2024-09-17. PMID:39288732. |
the present study aims to discover whether the destruction of the blood-brain barrier (bbb) mediated by matrix metalloproteinases 2 and matrix metalloproteinases 9 (mmp-2 and mmp-9) and subsequent neuronal apoptosis are involved in arsenic-induced cognitive impairment. |
2024-09-17 |
2024-09-20 |
mouse |
| J Liu, H Zhou, J Chen, Q Zuo, F Li. Baicalin Ameliorates Cartilage Injury in Rats With Osteoarthritis via Modulating miR-766-3p/AIFM1 Axis. Physiological research. vol 73. issue 4. 2024-09-12. PMID:39264083. |
tunel apoptosis staining was utilized to detect chondrocyte apoptosis, and western blotting examined autophagy-related markers (lc3, beclin, p62), extracellular matrix (ecm) synthesis-associated indices (col2a, acan, mmp13), and apoptosis-inducing factor mitochondrion-associated 1 (aifm1). |
2024-09-12 |
2024-09-14 |
rat |
| Shuai Wang, Kuanyu Wang, Cheng Li, Jing Chen, Xiangding Kon. Role of flavonoids in inhibiting triple-negative breast cancer. Frontiers in pharmacology. vol 15. 2024-09-11. PMID:39257397. |
this review focused on the primary mechanisms by which flavonoids from traditional chinese medicine extracts inhibit tnbc, including apoptosis, blocking of cell cycle and movement, regulation of extracellular matrix degradation, promotion of anti-angiogenesis, inhibition of aerobic glycolysis, and improvement in tumor microenvironment. |
2024-09-11 |
2024-09-13 |
Not clear |
| Palati Tuerxun, Takkun Ng, Jiadong Sun, Farong Ou, Xiaoshi Jia, Ke Zhao, Ping Zh. Lipoxin A4 modulates the PKA/CREB and NF-κB signaling pathway to mitigate chondrocyte catabolism and apoptosis in temporomandibular joint osteoarthritis. Experimental cell research. 2024-09-11. PMID:39260675. |
temporomandibular joint osteoarthritis (tmj-oa) is characterized by the degradation of the extracellular matrix (ecm) in cartilage and the apoptosis of chondrocytes, which is caused by inflammation and disruptions of chondrocyte metabolism and inflammation. |
2024-09-11 |
2024-09-14 |
rat |
| Ana Ercegovič Rot, Matija Hrovatin, Bor Bokalj, Ernestina Lavrih, Boris Tur. Cysteine Cathepsins: From Diagnosis to Targeted Therapy of Cancer. Biochimie. 2024-09-08. PMID:39245316. |
cysteine cathepsins influence cancer biology by participating in processes such as extracellular matrix degradation, angiogenesis, immune evasion, and apoptosis. |
2024-09-08 |
2024-09-11 |
Not clear |
| Hongjian Deng, Pengfei Xue, Xiaogang Zhou, Yuntao Wang, Wei Li. CCL4/CCR5 regulates chondrocyte biology and OA progression. Cytokine. vol 183. 2024-09-05. PMID:39236430. |
osteoarthritis (oa) is a common musculoskeletal disorder characterized by chondrocyte apoptosis and extracellular matrix degradation. |
2024-09-05 |
2024-09-08 |
Not clear |
| Juan Liu, Huiyun Wang, Mingyang Lu, Yuan Tian, Tingzhang H. The toxic effect of 2,6-di-tert-butylphenol on embryonic development in zebrafish (Danio rerio): Decreased survival rate, morphological abnormality, and abnormal vascular development. Environmental research. vol 262. issue Pt 1. 2024-08-31. PMID:39214490. |
transcriptome sequencing showed that 2,6-dtbp altered the mrna levels of genes associated with vascular development, oxidative stress, apoptosis, extracellular matrix components and receptors. |
2024-08-31 |
2024-09-04 |
zebrafish |
| Zhiwei Zhang, Bo Li, Shuqin Wu, Yuxin Yang, Binkang Wu, Qi Lai, Fuchong Lai, Fengbo Mo, Yufei Zhong, Song Wang, Runsheng Guo, Bin Zhan. Bergenin protects against osteoarthritis by inhibiting STAT3, NF-κB and Jun pathways and suppressing osteoclastogenesis. Scientific reports. vol 14. issue 1. 2024-08-31. PMID:39217193. |
ber suppressed il-1β-induced chondrocyte apoptosis and extracellular matrix catabolism by inhibiting the stat3, nf-κb and jun signalling pathway in vitro. |
2024-08-31 |
2024-09-04 |
mouse |
| Fahad Marafi, Abdulredha A Esmail, Mahmoud A Alfeeli, Alyaa Sade. 68Ga-Trivehexin PET/CT in Metastatic Non-Small Cell Lung Cancer to the Brain. Clinical nuclear medicine. 2024-08-27. PMID:39190399. |
it plays a role in facilitating invasion, inhibiting apoptosis, regulating expression of matrix metalloproteases, and activating tgf-β in carcinoma. |
2024-08-27 |
2024-08-30 |
Not clear |
| Retraction: Osteogenic protein-1 attenuates apoptosis and enhances matrix synthesis of nucleus pulposus cells under high-magnitude compression though inhibiting the p38 MAPK pathway. Bioscience reports. vol 44. issue 8. 2024-08-22. PMID:39171801. |
retraction: osteogenic protein-1 attenuates apoptosis and enhances matrix synthesis of nucleus pulposus cells under high-magnitude compression though inhibiting the p38 mapk pathway. |
2024-08-22 |
2024-08-24 |
Not clear |