Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Yue Zhang, Wenlong Yao, Jin Qiu, Wei Qian, Chang Zhu, Chuanhan Zhan. The involvement of down-regulation of Cdh1-APC in hippocampal neuronal apoptosis after global cerebral ischemia in rat. Neuroscience letters. vol 505. issue 2. 2012-08-16. PMID:21982804. |
the involvement of down-regulation of cdh1-apc in hippocampal neuronal apoptosis after global cerebral ischemia in rat. |
2012-08-16 |
2023-08-12 |
rat |
Yue Zhang, Wenlong Yao, Jin Qiu, Wei Qian, Chang Zhu, Chuanhan Zhan. The involvement of down-regulation of Cdh1-APC in hippocampal neuronal apoptosis after global cerebral ischemia in rat. Neuroscience letters. vol 505. issue 2. 2012-08-16. PMID:21982804. |
we found that, compared with sham group, the expression of cdh1 in hippocampus was significantly decreased on 1 and 3 days of reperfusion in ischemia group (p<0.05), while neuronal apoptosis were found in hippocampal ca1 region and the two downstream substrates of cdh1-apc (snon and skp2) were significantly increased after global cerebral ischemia (p<0.05). |
2012-08-16 |
2023-08-12 |
rat |
Yue Zhang, Wenlong Yao, Jin Qiu, Wei Qian, Chang Zhu, Chuanhan Zhan. The involvement of down-regulation of Cdh1-APC in hippocampal neuronal apoptosis after global cerebral ischemia in rat. Neuroscience letters. vol 505. issue 2. 2012-08-16. PMID:21982804. |
this study demonstrates that the down-regulation of cdh1-apc is associated with neuronal apoptosis in hippocampus following global cerebral ischemia. |
2012-08-16 |
2023-08-12 |
rat |
Lou-yan Ma, Dong-min Zhang, Yong Tang, Yang Lu, Yin Zhang, Yuan Gao, Li Xia, Ke-xiang Zhao, Li-Yin Chai, Qian Xia. Ghrelin-attenuated cognitive dysfunction in streptozotocin-induced diabetic rats. Alzheimer disease and associated disorders. vol 25. issue 4. 2012-08-13. PMID:22005105. |
the hippocampus neuronal apoptosis was measured by terminal deoxynucleotidyl transferase dutp nick end labeling method. |
2012-08-13 |
2023-08-12 |
rat |
Lou-yan Ma, Dong-min Zhang, Yong Tang, Yang Lu, Yin Zhang, Yuan Gao, Li Xia, Ke-xiang Zhao, Li-Yin Chai, Qian Xia. Ghrelin-attenuated cognitive dysfunction in streptozotocin-induced diabetic rats. Alzheimer disease and associated disorders. vol 25. issue 4. 2012-08-13. PMID:22005105. |
our results showed that the changes of bdnf, creb, and hippocampus neuronal apoptosis might be involved in the pathogenesis of diabetic encephalopathy. |
2012-08-13 |
2023-08-12 |
rat |
Lou-yan Ma, Dong-min Zhang, Yong Tang, Yang Lu, Yin Zhang, Yuan Gao, Li Xia, Ke-xiang Zhao, Li-Yin Chai, Qian Xia. Ghrelin-attenuated cognitive dysfunction in streptozotocin-induced diabetic rats. Alzheimer disease and associated disorders. vol 25. issue 4. 2012-08-13. PMID:22005105. |
we suggested that ghrelin improved cognitive ability in streptozotocin-induced diabetic rats by improving the expressions of bdnf and creb and by attenuating hippocampus neuronal apoptosis. |
2012-08-13 |
2023-08-12 |
rat |
Sylwia Owczarek, Jack Hou, Thomas Secher, Lars V Kristianse. Phencyclidine treatment increases NR2A and NR2B N-methyl-D-aspartate receptor subunit expression in rats. Neuroreport. vol 22. issue 17. 2012-08-08. PMID:22015741. |
administration of noncompetitive n-methyl-d-aspartate receptor (nmdar) antagonist phencyclidine to rats on postnatal days 7, 9, and 11 induces apoptosis in prefrontal cortex and hippocampus. |
2012-08-08 |
2023-08-12 |
rat |
Ying Cheng, Adia Thomas, Feras Mardini, Shannon L Bianchi, Junxia X Tang, Jun Peng, Huafeng Wei, Maryellen F Eckenhoff, Roderic G Eckenhoff, Richard J Lev. Neurodevelopmental consequences of sub-clinical carbon monoxide exposure in newborn mice. PloS one. vol 7. issue 2. 2012-07-31. PMID:22348142. |
three hour exposure to 5 ppm or 100 ppm co impaired cytochrome c release, caspase-3 activation, and apoptosis in neocortex and hippocampus of 10 day old cd-1 mice. |
2012-07-31 |
2023-08-12 |
mouse |
Tatiana Barichello, Jaqueline S Generoso, Allan Collodel, Ana Paula Moreira, Cleonice M Michelon, Alice Raupp, Andreza L Cipriano, Daiane de Bittencourt Fraga, Alexandra I Zugn. Acetylcholinesterase activity in the rat brain after pneumococcal meningitis. Microbiology and immunology. vol 56. issue 3. 2012-07-24. PMID:22188584. |
pneumococcal meningitis is a life-threatening disease characterized by acute purulent infection of the meninges causing neuronal injury, cortical necrosis and hippocampal apoptosis. |
2012-07-24 |
2023-08-12 |
rat |
Clara J Yuan, Jovy Marie D Quiocho, Airee Kim, Sunmee Wee, Chitra D Mandya. Extended access methamphetamine decreases immature neurons in the hippocampus which results from loss and altered development of neural progenitors without altered dynamics of the S-phase of the cell cycle. Pharmacology, biochemistry, and behavior. vol 100. issue 1. 2012-07-23. PMID:21855565. |
methamphetamine concomitantly increased hippocampal apoptosis, changes that were evident during the earlier days of self-administration. |
2012-07-23 |
2023-08-12 |
rat |
Clara J Yuan, Jovy Marie D Quiocho, Airee Kim, Sunmee Wee, Chitra D Mandya. Extended access methamphetamine decreases immature neurons in the hippocampus which results from loss and altered development of neural progenitors without altered dynamics of the S-phase of the cell cycle. Pharmacology, biochemistry, and behavior. vol 100. issue 1. 2012-07-23. PMID:21855565. |
these findings demonstrate that methamphetamine self-administration initiates allostatic changes in adult neuroplasticity maintained by the hippocampus, including increased apoptosis, and altered dynamics of hippocampal neural progenitors. |
2012-07-23 |
2023-08-12 |
rat |
Maria Śmiałowska, Krystyna Gołembiowska, Małgorzata Kajta, Barbara Zięba, Anna Dziubina, Helena Domi. Selective mGluR1 antagonist EMQMCM inhibits the kainate-induced excitotoxicity in primary neuronal cultures and in the rat hippocampus. Neurotoxicity research. vol 21. issue 4. 2012-07-23. PMID:22144346. |
in in vitro studies on mouse primary cortical and hippocampal neuronal cultures, incubation with ka (150 μm) induced strong degeneration [measured as lactate dehydrogenase (ldh) efflux] and apoptosis (measured as caspase-3 activity). |
2012-07-23 |
2023-08-12 |
mouse |
Aline Silva de Miranda, David Henrique Rodrigues, Débora Cristina Guerra Amaral, Roberta Dayrell de Lima Campos, Daniel Cisalpino, Márcia Carvalho Vilela, Norinne Lacerda-Queiroz, Kátia Paulino Ribeiro de Souza, Juliana Priscila Vago, Marco Antônio Campos, Erna Geesien Kroon, Danielle da Glória de Souza, Mauro Martins Teixeira, Antônio Lúcio Teixeira, Milene Alvarenga Rachi. Dengue-3 encephalitis promotes anxiety-like behavior in mice. Behavioural brain research. vol 230. issue 1. 2012-07-23. PMID:22366269. |
this study described anxiety-like behavior, hippocampal inflammation and neuronal apoptosis associated with denv-3 infection in the central nervous system. |
2012-07-23 |
2023-08-12 |
mouse |
Ji-sheng Nie, Jie Zhao, Jing Wan. [Pathological changes and cell apoptosis of hippocampus in rats induced by repeated injection of benzopyrene in lateral ventricle]. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases. vol 27. issue 1. 2012-07-16. PMID:19224694. |
[pathological changes and cell apoptosis of hippocampus in rats induced by repeated injection of benzopyrene in lateral ventricle]. |
2012-07-16 |
2023-08-12 |
rat |
J S Kim, M Yang, J Kim, D Lee, J C Kim, T Shin, S H Kim, C Moo. Comparison of the dose-response relationship of radiation-induced apoptosis in the hippocampal dentate gyrus and intestinal crypt of adult mice. Radiation protection dosimetry. vol 148. issue 4. 2012-07-16. PMID:21515618. |
comparison of the dose-response relationship of radiation-induced apoptosis in the hippocampal dentate gyrus and intestinal crypt of adult mice. |
2012-07-16 |
2023-08-12 |
mouse |
J S Kim, M Yang, J Kim, D Lee, J C Kim, T Shin, S H Kim, C Moo. Comparison of the dose-response relationship of radiation-induced apoptosis in the hippocampal dentate gyrus and intestinal crypt of adult mice. Radiation protection dosimetry. vol 148. issue 4. 2012-07-16. PMID:21515618. |
the present study compared the dose-response curves for the frequency of apoptosis in mouse hippocampal dentate gyrus (dg) and intestinal crypt using whole-body gamma irradiation. |
2012-07-16 |
2023-08-12 |
mouse |
Iwona Inkielewicz-Stepniak, Marek W Radomski, Michal Woznia. Fisetin prevents fluoride- and dexamethasone-induced oxidative damage in osteoblast and hippocampal cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 50. issue 3-4. 2012-07-16. PMID:22198064. |
the aim of this study was to evaluate the effect of fluoride (f) and dexamethasone (dex) co-exposure on oxidative stress and apoptosis in osteoblast-like mc3t3-e1 and hippocampal ht22 cell lines. |
2012-07-16 |
2023-08-12 |
Not clear |
Yu Tang, Qinghua Jia, Ping Ma, Fujun Li, Tongde Lv, Xiaoqin H. [The effects of lead exposure on primary cultured hippocampus neurons apoptosis and the expressions of Bcl-2, Bax, p53 and NOS1]. Wei sheng yan jiu = Journal of hygiene research. vol 39. issue 2. 2012-07-06. PMID:20459046. |
[the effects of lead exposure on primary cultured hippocampus neurons apoptosis and the expressions of bcl-2, bax, p53 and nos1]. |
2012-07-06 |
2023-08-12 |
Not clear |
Yu Tang, Qinghua Jia, Ping Ma, Fujun Li, Tongde Lv, Xiaoqin H. [The effects of lead exposure on primary cultured hippocampus neurons apoptosis and the expressions of Bcl-2, Bax, p53 and NOS1]. Wei sheng yan jiu = Journal of hygiene research. vol 39. issue 2. 2012-07-06. PMID:20459046. |
to observe effects of plumbum on the apoptosis of primary cultured hippocampus neurons. |
2012-07-06 |
2023-08-12 |
Not clear |
Chia-Fu Chang, Hui-Ju Huang, Hsin-Chen Lee, Kai-Chih Hung, Rong-Tsun Wu, Anya Maan-Yuh Li. Melatonin attenuates kainic acid-induced neurotoxicity in mouse hippocampus via inhibition of autophagy and α-synuclein aggregation. Journal of pineal research. vol 52. issue 3. 2012-07-05. PMID:22212051. |
furthermore, atg7 sirna attenuated ka-induced activation of caspases 3/12 (biomarkers of apoptosis) and hippocampal neuronal loss, suggesting a pro-apoptotic role of autophagy in the ka-induced neurotoxicity. |
2012-07-05 |
2023-08-12 |
mouse |