| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lou-yan Ma, Dong-min Zhang, Yong Tang, Yang Lu, Yin Zhang, Yuan Gao, Li Xia, Ke-xiang Zhao, Li-Yin Chai, Qian Xia. Ghrelin-attenuated cognitive dysfunction in streptozotocin-induced diabetic rats. Alzheimer disease and associated disorders. vol 25. issue 4. 2012-08-13. PMID:22005105. |
the hippocampus neuronal apoptosis was measured by terminal deoxynucleotidyl transferase dutp nick end labeling method. |
2012-08-13 |
2023-08-12 |
rat |
| Lou-yan Ma, Dong-min Zhang, Yong Tang, Yang Lu, Yin Zhang, Yuan Gao, Li Xia, Ke-xiang Zhao, Li-Yin Chai, Qian Xia. Ghrelin-attenuated cognitive dysfunction in streptozotocin-induced diabetic rats. Alzheimer disease and associated disorders. vol 25. issue 4. 2012-08-13. PMID:22005105. |
our results showed that the changes of bdnf, creb, and hippocampus neuronal apoptosis might be involved in the pathogenesis of diabetic encephalopathy. |
2012-08-13 |
2023-08-12 |
rat |
| Lou-yan Ma, Dong-min Zhang, Yong Tang, Yang Lu, Yin Zhang, Yuan Gao, Li Xia, Ke-xiang Zhao, Li-Yin Chai, Qian Xia. Ghrelin-attenuated cognitive dysfunction in streptozotocin-induced diabetic rats. Alzheimer disease and associated disorders. vol 25. issue 4. 2012-08-13. PMID:22005105. |
we suggested that ghrelin improved cognitive ability in streptozotocin-induced diabetic rats by improving the expressions of bdnf and creb and by attenuating hippocampus neuronal apoptosis. |
2012-08-13 |
2023-08-12 |
rat |
| Sylwia Owczarek, Jack Hou, Thomas Secher, Lars V Kristianse. Phencyclidine treatment increases NR2A and NR2B N-methyl-D-aspartate receptor subunit expression in rats. Neuroreport. vol 22. issue 17. 2012-08-08. PMID:22015741. |
administration of noncompetitive n-methyl-d-aspartate receptor (nmdar) antagonist phencyclidine to rats on postnatal days 7, 9, and 11 induces apoptosis in prefrontal cortex and hippocampus. |
2012-08-08 |
2023-08-12 |
rat |
| Ying Cheng, Adia Thomas, Feras Mardini, Shannon L Bianchi, Junxia X Tang, Jun Peng, Huafeng Wei, Maryellen F Eckenhoff, Roderic G Eckenhoff, Richard J Lev. Neurodevelopmental consequences of sub-clinical carbon monoxide exposure in newborn mice. PloS one. vol 7. issue 2. 2012-07-31. PMID:22348142. |
three hour exposure to 5 ppm or 100 ppm co impaired cytochrome c release, caspase-3 activation, and apoptosis in neocortex and hippocampus of 10 day old cd-1 mice. |
2012-07-31 |
2023-08-12 |
mouse |
| Tatiana Barichello, Jaqueline S Generoso, Allan Collodel, Ana Paula Moreira, Cleonice M Michelon, Alice Raupp, Andreza L Cipriano, Daiane de Bittencourt Fraga, Alexandra I Zugn. Acetylcholinesterase activity in the rat brain after pneumococcal meningitis. Microbiology and immunology. vol 56. issue 3. 2012-07-24. PMID:22188584. |
pneumococcal meningitis is a life-threatening disease characterized by acute purulent infection of the meninges causing neuronal injury, cortical necrosis and hippocampal apoptosis. |
2012-07-24 |
2023-08-12 |
rat |
| Clara J Yuan, Jovy Marie D Quiocho, Airee Kim, Sunmee Wee, Chitra D Mandya. Extended access methamphetamine decreases immature neurons in the hippocampus which results from loss and altered development of neural progenitors without altered dynamics of the S-phase of the cell cycle. Pharmacology, biochemistry, and behavior. vol 100. issue 1. 2012-07-23. PMID:21855565. |
methamphetamine concomitantly increased hippocampal apoptosis, changes that were evident during the earlier days of self-administration. |
2012-07-23 |
2023-08-12 |
rat |
| Clara J Yuan, Jovy Marie D Quiocho, Airee Kim, Sunmee Wee, Chitra D Mandya. Extended access methamphetamine decreases immature neurons in the hippocampus which results from loss and altered development of neural progenitors without altered dynamics of the S-phase of the cell cycle. Pharmacology, biochemistry, and behavior. vol 100. issue 1. 2012-07-23. PMID:21855565. |
these findings demonstrate that methamphetamine self-administration initiates allostatic changes in adult neuroplasticity maintained by the hippocampus, including increased apoptosis, and altered dynamics of hippocampal neural progenitors. |
2012-07-23 |
2023-08-12 |
rat |
| Maria Śmiałowska, Krystyna Gołembiowska, Małgorzata Kajta, Barbara Zięba, Anna Dziubina, Helena Domi. Selective mGluR1 antagonist EMQMCM inhibits the kainate-induced excitotoxicity in primary neuronal cultures and in the rat hippocampus. Neurotoxicity research. vol 21. issue 4. 2012-07-23. PMID:22144346. |
in in vitro studies on mouse primary cortical and hippocampal neuronal cultures, incubation with ka (150 μm) induced strong degeneration [measured as lactate dehydrogenase (ldh) efflux] and apoptosis (measured as caspase-3 activity). |
2012-07-23 |
2023-08-12 |
mouse |
| Aline Silva de Miranda, David Henrique Rodrigues, Débora Cristina Guerra Amaral, Roberta Dayrell de Lima Campos, Daniel Cisalpino, Márcia Carvalho Vilela, Norinne Lacerda-Queiroz, Kátia Paulino Ribeiro de Souza, Juliana Priscila Vago, Marco Antônio Campos, Erna Geesien Kroon, Danielle da Glória de Souza, Mauro Martins Teixeira, Antônio Lúcio Teixeira, Milene Alvarenga Rachi. Dengue-3 encephalitis promotes anxiety-like behavior in mice. Behavioural brain research. vol 230. issue 1. 2012-07-23. PMID:22366269. |
this study described anxiety-like behavior, hippocampal inflammation and neuronal apoptosis associated with denv-3 infection in the central nervous system. |
2012-07-23 |
2023-08-12 |
mouse |
| Ji-sheng Nie, Jie Zhao, Jing Wan. [Pathological changes and cell apoptosis of hippocampus in rats induced by repeated injection of benzopyrene in lateral ventricle]. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases. vol 27. issue 1. 2012-07-16. PMID:19224694. |
[pathological changes and cell apoptosis of hippocampus in rats induced by repeated injection of benzopyrene in lateral ventricle]. |
2012-07-16 |
2023-08-12 |
rat |
| J S Kim, M Yang, J Kim, D Lee, J C Kim, T Shin, S H Kim, C Moo. Comparison of the dose-response relationship of radiation-induced apoptosis in the hippocampal dentate gyrus and intestinal crypt of adult mice. Radiation protection dosimetry. vol 148. issue 4. 2012-07-16. PMID:21515618. |
comparison of the dose-response relationship of radiation-induced apoptosis in the hippocampal dentate gyrus and intestinal crypt of adult mice. |
2012-07-16 |
2023-08-12 |
mouse |
| J S Kim, M Yang, J Kim, D Lee, J C Kim, T Shin, S H Kim, C Moo. Comparison of the dose-response relationship of radiation-induced apoptosis in the hippocampal dentate gyrus and intestinal crypt of adult mice. Radiation protection dosimetry. vol 148. issue 4. 2012-07-16. PMID:21515618. |
the present study compared the dose-response curves for the frequency of apoptosis in mouse hippocampal dentate gyrus (dg) and intestinal crypt using whole-body gamma irradiation. |
2012-07-16 |
2023-08-12 |
mouse |
| Iwona Inkielewicz-Stepniak, Marek W Radomski, Michal Woznia. Fisetin prevents fluoride- and dexamethasone-induced oxidative damage in osteoblast and hippocampal cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 50. issue 3-4. 2012-07-16. PMID:22198064. |
the aim of this study was to evaluate the effect of fluoride (f) and dexamethasone (dex) co-exposure on oxidative stress and apoptosis in osteoblast-like mc3t3-e1 and hippocampal ht22 cell lines. |
2012-07-16 |
2023-08-12 |
Not clear |
| Yu Tang, Qinghua Jia, Ping Ma, Fujun Li, Tongde Lv, Xiaoqin H. [The effects of lead exposure on primary cultured hippocampus neurons apoptosis and the expressions of Bcl-2, Bax, p53 and NOS1]. Wei sheng yan jiu = Journal of hygiene research. vol 39. issue 2. 2012-07-06. PMID:20459046. |
[the effects of lead exposure on primary cultured hippocampus neurons apoptosis and the expressions of bcl-2, bax, p53 and nos1]. |
2012-07-06 |
2023-08-12 |
Not clear |
| Yu Tang, Qinghua Jia, Ping Ma, Fujun Li, Tongde Lv, Xiaoqin H. [The effects of lead exposure on primary cultured hippocampus neurons apoptosis and the expressions of Bcl-2, Bax, p53 and NOS1]. Wei sheng yan jiu = Journal of hygiene research. vol 39. issue 2. 2012-07-06. PMID:20459046. |
to observe effects of plumbum on the apoptosis of primary cultured hippocampus neurons. |
2012-07-06 |
2023-08-12 |
Not clear |
| Chia-Fu Chang, Hui-Ju Huang, Hsin-Chen Lee, Kai-Chih Hung, Rong-Tsun Wu, Anya Maan-Yuh Li. Melatonin attenuates kainic acid-induced neurotoxicity in mouse hippocampus via inhibition of autophagy and α-synuclein aggregation. Journal of pineal research. vol 52. issue 3. 2012-07-05. PMID:22212051. |
furthermore, atg7 sirna attenuated ka-induced activation of caspases 3/12 (biomarkers of apoptosis) and hippocampal neuronal loss, suggesting a pro-apoptotic role of autophagy in the ka-induced neurotoxicity. |
2012-07-05 |
2023-08-12 |
mouse |
| Joshua C Bis, Charles DeCarli, Albert Vernon Smith, Fedde van der Lijn, Fabrice Crivello, Myriam Fornage, Stephanie Debette, Joshua M Shulman, Helena Schmidt, Velandai Srikanth, Maaike Schuur, Lei Yu, Seung-Hoan Choi, Sigurdur Sigurdsson, Benjamin F J Verhaaren, Anita L DeStefano, Jean-Charles Lambert, Clifford R Jack, Maksim Struchalin, Jim Stankovich, Carla A Ibrahim-Verbaas, Debra Fleischman, Alex Zijdenbos, Tom den Heijer, Bernard Mazoyer, Laura H Coker, Christian Enzinger, Patrick Danoy, Najaf Amin, Konstantinos Arfanakis, Mark A van Buchem, Renée F A G de Bruijn, Alexa Beiser, Carole Dufouil, Juebin Huang, Margherita Cavalieri, Russell Thomson, Wiro J Niessen, Lori B Chibnik, Gauti K Gislason, Albert Hofman, Aleksandra Pikula, Philippe Amouyel, Kevin B Freeman, Thanh G Phan, Ben A Oostra, Jason L Stein, Sarah E Medland, Alejandro Arias Vasquez, Derrek P Hibar, Margaret J Wright, Barbara Franke, Nicholas G Martin, Paul M Thompson, Michael A Nalls, Andre G Uitterlinden, Rhoda Au, Alexis Elbaz, Richard J Beare, John C van Swieten, Oscar L Lopez, Tamara B Harris, Vincent Chouraki, Monique M B Breteler, Philip L De Jager, James T Becker, Meike W Vernooij, David Knopman, Franz Fazekas, Philip A Wolf, Aad van der Lugt, Vilmundur Gudnason, W T Longstreth, Matthew A Brown, David A Bennett, Cornelia M van Duijn, Thomas H Mosley, Reinhold Schmidt, Christophe Tzourio, Lenore J Launer, M Arfan Ikram, Sudha Seshadr. Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nature genetics. vol 44. issue 5. 2012-07-02. PMID:22504421. |
these associations implicate genes related to apoptosis (hrk), development (wif1), oxidative stress (msr3b), ubiquitination (fbxw8) and neuronal migration (astn2), as well as enzymes targeted by new diabetes medications (dpp4), indicating new genetic influences on hippocampal size and possibly the risk of cognitive decline and dementia. |
2012-07-02 |
2023-08-12 |
Not clear |
| Yu-Xian Li, Zuo-Li Xia, Lian-Bi Chen, Wen-Jing Ye, Ming-Feng Yang, Qiao-Ling Su. [The changes of bcl-2, bax expression and neuron apoptosis in the hippocampus after the blockade of cervical lymphatics of rats]. Sheng li xue bao : [Acta physiologica Sinica]. vol 57. issue 1. 2012-06-28. PMID:15719136. |
[the changes of bcl-2, bax expression and neuron apoptosis in the hippocampus after the blockade of cervical lymphatics of rats]. |
2012-06-28 |
2023-08-12 |
rat |
| Yu-Xian Li, Zuo-Li Xia, Lian-Bi Chen, Wen-Jing Ye, Ming-Feng Yang, Qiao-Ling Su. [The changes of bcl-2, bax expression and neuron apoptosis in the hippocampus after the blockade of cervical lymphatics of rats]. Sheng li xue bao : [Acta physiologica Sinica]. vol 57. issue 1. 2012-06-28. PMID:15719136. |
to investigate the changes in bcl-2, bax expression and neuron apoptosis in the hippocampus after the blockade of cervical lymphatics, the model of lymphostatic encephalopathy was established by occluding and removing both the superficial and deep cervical lymph nodes in rats. |
2012-06-28 |
2023-08-12 |
rat |