| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Simon J Fung, MingChu Xi, JianHua Zhang, Sharon Sampogna, Michael H Chas. Apnea produces excitotoxic hippocampal synapses and neuronal apoptosis. Experimental neurology. vol 238. issue 2. 2013-01-21. PMID:22921462. |
in addition, to substantiate an anatomical basis for the cognitive dysfunction that occurs in osa patients, we examined the effects of apnea with respect to neurodegenerative changes (apoptosis) in the same hippocampal pathway. |
2013-01-21 |
2023-08-12 |
rat |
| Oumei Cheng, Zhenhua Li, Yu Han, Qingsong Jiang, Yong Yan, Ke Chen. Baicalin improved the spatial learning ability of global ischemia/reperfusion rats by reducing hippocampal apoptosis. Brain research. vol 1470. 2013-01-15. PMID:22796597. |
baicalin improved the spatial learning ability of global ischemia/reperfusion rats by reducing hippocampal apoptosis. |
2013-01-15 |
2023-08-12 |
rat |
| Yu-yun Hu, Qing-jun Li, Wen-bin Li, Li-hua Guo, Sai-chun Ch. [Formalin inflammatory pain induced hippocampal neuronal apoptosis of rats]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 25. issue 2. 2013-01-14. PMID:21189548. |
[formalin inflammatory pain induced hippocampal neuronal apoptosis of rats]. |
2013-01-14 |
2023-08-12 |
rat |
| Yu-yun Hu, Qing-jun Li, Wen-bin Li, Li-hua Guo, Sai-chun Ch. [Formalin inflammatory pain induced hippocampal neuronal apoptosis of rats]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 25. issue 2. 2013-01-14. PMID:21189548. |
to investigate whether formalin inflammatory pain can induce hippocampal neuronal apoptosis of rats or not. |
2013-01-14 |
2023-08-12 |
rat |
| Q Zhang, M Ding, X R Gao, F Din. Pyrroloquinoline quinone rescues hippocampal neurons from glutamate-induced cell death through activation of Nrf2 and up-regulation of antioxidant genes. Genetics and molecular research : GMR. vol 11. issue 3. 2013-01-08. PMID:22843070. |
pyrroloquinoline quinone (pqq) has been shown to protect primary cultured hippocampal neurons from glutamate-induced cell apoptosis by scavenging reactive oxygen species (ros) and activating phosphatidylinositol-3-kinase (pi3k)/akt signaling. |
2013-01-08 |
2023-08-12 |
Not clear |
| Juan Perucho, Maria J Casarejos, Ana Gomez, Rosa M Solano, Justo Garcia de Yébenes, Maria A Men. Trehalose protects from aggravation of amyloid pathology induced by isoflurane anesthesia in APP(swe) mutant mice. Current Alzheimer research. vol 9. issue 3. 2012-12-21. PMID:22272607. |
in this study, we have shown that repetitive exposure to isoflurane in pre-symptomatic mature app(swe) mice increases apoptosis in hippocampus and cerebral cortex, enhances astrogliosis and the expression of gfap and that these effects are prevented by co-treatment with trehalose, a disaccharide with known effects as enhancer of autophagy. |
2012-12-21 |
2023-08-12 |
mouse |
| Kaiming Huo, Yanyan Sun, Hongfu Li, Xiaonan Du, Xiaoyang Wang, Niklas Karlsson, Changlian Zhu, Klas Blomgre. Lithium reduced neural progenitor apoptosis in the hippocampus and ameliorated functional deficits after irradiation to the immature mouse brain. Molecular and cellular neurosciences. vol 51. issue 1-2. 2012-12-20. PMID:22800605. |
lithium reduced neural progenitor apoptosis in the hippocampus and ameliorated functional deficits after irradiation to the immature mouse brain. |
2012-12-20 |
2023-08-12 |
mouse |
| Kaiming Huo, Yanyan Sun, Hongfu Li, Xiaonan Du, Xiaoyang Wang, Niklas Karlsson, Changlian Zhu, Klas Blomgre. Lithium reduced neural progenitor apoptosis in the hippocampus and ameliorated functional deficits after irradiation to the immature mouse brain. Molecular and cellular neurosciences. vol 51. issue 1-2. 2012-12-20. PMID:22800605. |
in summary, lithium administration could decrease ir-induced neural progenitor cell apoptosis in the gcl of the hippocampus and ameliorate learning impairments. |
2012-12-20 |
2023-08-12 |
mouse |
| Yougen Luo, Xiaoai Liu, Qisheng Zheng, Xiaomei Wan, Shuichang Ouyang, Yedong Yin, Xiaojing Sui, Jianjun Liu, Xifei Yan. Hydrogen sulfide prevents hypoxia-induced apoptosis via inhibition of an H2O2-activated calcium signaling pathway in mouse hippocampal neurons. Biochemical and biophysical research communications. vol 425. issue 2. 2012-12-18. PMID:22846576. |
hydrogen sulfide prevents hypoxia-induced apoptosis via inhibition of an h2o2-activated calcium signaling pathway in mouse hippocampal neurons. |
2012-12-18 |
2023-08-12 |
mouse |
| Yougen Luo, Xiaoai Liu, Qisheng Zheng, Xiaomei Wan, Shuichang Ouyang, Yedong Yin, Xiaojing Sui, Jianjun Liu, Xifei Yan. Hydrogen sulfide prevents hypoxia-induced apoptosis via inhibition of an H2O2-activated calcium signaling pathway in mouse hippocampal neurons. Biochemical and biophysical research communications. vol 425. issue 2. 2012-12-18. PMID:22846576. |
furthermore, we found that pretreatment with nahs could significantly inhibit hypoxia-induced neuronal apoptosis, which was also inhibited by peg-catalase or the inositol 1,4,5-triphosphate (ip(3)) receptor blocker xestospongin c. taken together, these findings suggest that h(2)s inhibits hypoxia-induced apoptosis through inhibition of a ros (mainly h(2)o(2))-activated ca(2+) signaling pathway in mouse hippocampal neurons. |
2012-12-18 |
2023-08-12 |
mouse |
| Ehab A Dayyat, Shelley X Zhang, Yang Wang, Zixi Jack Cheng, David Goza. Exogenous erythropoietin administration attenuates intermittent hypoxia-induced cognitive deficits in a murine model of sleep apnea. BMC neuroscience. vol 13. 2012-12-14. PMID:22759774. |
in rodents, exposure to intermittent hypoxia (ih), a hallmark of obstructive sleep apnea (osa), is associated with neurobehavioral impairments, increased apoptosis in the hippocampus and cortex, as well as increased oxidant stress and inflammation. |
2012-12-14 |
2023-08-12 |
Not clear |
| Jing Yang, Tian-Zuo Li, Bing-Xi Zhan. [Effects of propofol on the anoxic/reoxygenation responses by c-fos and apoptosis in primary cultured hippocampal neurons]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 20. issue 1. 2012-12-11. PMID:21162307. |
[effects of propofol on the anoxic/reoxygenation responses by c-fos and apoptosis in primary cultured hippocampal neurons]. |
2012-12-11 |
2023-08-12 |
Not clear |
| Guoqiang Xing, Ming Ren, J Timothy O'Neill, Pushpa Sharma, Ajay Verma, William D Watso. Pyruvate dehydrogenase phosphatase1 mRNA expression is divergently and dynamically regulated between rat cerebral cortex, hippocampus and thalamus after traumatic brain injury: a potential biomarker of TBI-induced hyper- and hypo-glycaemia and neuronal vulnerability. Neuroscience letters. vol 525. issue 2. 2012-12-10. PMID:22884618. |
pdp1 mrna level increased transiently in ipsilateral hippocampal dentate gyrus and ca1-3 subfields 4 h post cci (p<0.01) but decreased significantly 24 h and 72 h (p<0.01) post cci, coinciding with a marked increase in neuronal apoptosis in ipsilateral hippocampus 24 h post cci. |
2012-12-10 |
2023-08-12 |
rat |
| J G Zhou, J C Liu, Y Q Fan. [Study on the effect of hyperbaric oxygen on apoptosis in the CA1 region of hippocampus following forebrain ischemia reperfusion]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 17. issue 1. 2012-12-03. PMID:21171452. |
[study on the effect of hyperbaric oxygen on apoptosis in the ca1 region of hippocampus following forebrain ischemia reperfusion]. |
2012-12-03 |
2023-08-12 |
Not clear |
| Lan-Run Gui, Wen-Bin Li, Bing-Lie Zhan. [Activation of PACAP receptor could protect cultured hippocampal neurons against beta amyloid peptide induced neurotoxicity]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 18. issue 2. 2012-12-03. PMID:21179800. |
to observe the protective role of pituitary adenylate cyclase activating polypeptide (pacap) on hippocampal neuronal apoptosis induced by beta amyloid peptide in the culture. |
2012-12-03 |
2023-08-12 |
Not clear |
| Ai-Shi Ding, Fu-Zhuang Wang, Li-Ying W. [Effects of anoxia/reoxygenation on Fos and Jun expression and apoptosis in cultured rat hippocampal neurons]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 18. issue 3. 2012-12-03. PMID:21180051. |
[effects of anoxia/reoxygenation on fos and jun expression and apoptosis in cultured rat hippocampal neurons]. |
2012-12-03 |
2023-08-12 |
rat |
| Ai-Shi Ding, Fu-Zhuang Wang, Li-Ying W. [Effects of anoxia/reoxygenation on Fos and Jun expression and apoptosis in cultured rat hippocampal neurons]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 18. issue 3. 2012-12-03. PMID:21180051. |
to investigate the effects of anoxia/reoxygenation on fos and jun expression and apoptosis in cultured rat hippocampal neurons. |
2012-12-03 |
2023-08-12 |
rat |
| Jianbin Zhang, Tongjian Cai, Fang Zhao, Ting Yao, Yaoming Chen, Xinqin Liu, Wenjing Luo, Jingyuan Che. The role of α-synuclein and tau hyperphosphorylation-mediated autophagy and apoptosis in lead-induced learning and memory injury. International journal of biological sciences. vol 8. issue 7. 2012-11-28. PMID:22811615. |
these can enhance type ii program death (autophgy) and type i program death (apoptosis) in hippocampus, and impair the ability of learning and memory of rats. |
2012-11-28 |
2023-08-12 |
human |
| Zhen Gu, Yahong Liu, Yongjie Zhang, Shulei Jin, Qi Chen, David Goltzman, Andrew Karaplis, Dengshun Mia. Absence of PTHrP nuclear localization and carboxyl terminus sequences leads to abnormal brain development and function. PloS one. vol 7. issue 7. 2012-11-28. PMID:22844494. |
results showed that pthrp knock-in mice display abnormal brain shape and structures; decreased neural cell proliferative capacity and increased apoptosis associated with up-regulation of cyclin dependent kinase inhibitors p16, p21, p27 and p53 and down-regulation of the bmi-1 oncogene; delayed neural cell differentiation; and impaired hippocampal synaptic transmission and plasticity. |
2012-11-28 |
2023-08-12 |
mouse |
| Kandaswamy Selvakumar, Senthamilselvan Bavithra, Muralidharan Suganthi, Chellakan Selvanesan Benson, Perumal Elumalai, Ramachandran Arunkumar, Gunasekaran Krishnamoorthy, Prabhu Venkataraman, Jagadeesan Arunakara. Protective role of quercetin on PCBs-induced oxidative stress and apoptosis in hippocampus of adult rats. Neurochemical research. vol 37. issue 4. 2012-11-26. PMID:22127757. |
protective role of quercetin on pcbs-induced oxidative stress and apoptosis in hippocampus of adult rats. |
2012-11-26 |
2023-08-12 |
rat |