| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Si-Qin Huang, Cheng-Lin Tang, Shan-Quan Sun, Cheng Yang, Jin Xu, Ke-Jian Wang, Wei-Tian Lu, Juan Huang, Fei Zhuo, Guo-Ping Qiu, Xiu-Yu Wu, Wei Q. Demyelination initiated by oligodendrocyte apoptosis through enhancing endoplasmic reticulum-mitochondria interactions and Id2 expression after compressed spinal cord injury in rats. CNS neuroscience & therapeutics. vol 20. issue 1. 2014-09-29. PMID:23937638. |
demyelination initiated by oligodendrocyte apoptosis through enhancing endoplasmic reticulum-mitochondria interactions and id2 expression after compressed spinal cord injury in rats. |
2014-09-29 |
2023-08-12 |
rat |
| Si-Qin Huang, Cheng-Lin Tang, Shan-Quan Sun, Cheng Yang, Jin Xu, Ke-Jian Wang, Wei-Tian Lu, Juan Huang, Fei Zhuo, Guo-Ping Qiu, Xiu-Yu Wu, Wei Q. Demyelination initiated by oligodendrocyte apoptosis through enhancing endoplasmic reticulum-mitochondria interactions and Id2 expression after compressed spinal cord injury in rats. CNS neuroscience & therapeutics. vol 20. issue 1. 2014-09-29. PMID:23937638. |
oligodendrocyte apoptosis is involved in triggering demyelination. |
2014-09-29 |
2023-08-12 |
rat |
| Si-Qin Huang, Cheng-Lin Tang, Shan-Quan Sun, Cheng Yang, Jin Xu, Ke-Jian Wang, Wei-Tian Lu, Juan Huang, Fei Zhuo, Guo-Ping Qiu, Xiu-Yu Wu, Wei Q. Demyelination initiated by oligodendrocyte apoptosis through enhancing endoplasmic reticulum-mitochondria interactions and Id2 expression after compressed spinal cord injury in rats. CNS neuroscience & therapeutics. vol 20. issue 1. 2014-09-29. PMID:23937638. |
the relative effect of oligodendrocyte apoptosis on csci-induced demyelination and the mechanism of apoptosis remain unclear. |
2014-09-29 |
2023-08-12 |
rat |
| Estíbaliz González-Fernández, María Victoria Sánchez-Gómez, Alberto Pérez-Samartín, Rogelio O Arellano, Carlos Matut. A3 Adenosine receptors mediate oligodendrocyte death and ischemic damage to optic nerve. Glia. vol 62. issue 2. 2014-09-26. PMID:24311446. |
oligodendrocyte apoptosis induced by a3 receptor activation was caspase-dependent and caspase-independent. |
2014-09-26 |
2023-08-12 |
rat |
| B Liu, X Chen, Z Q Wang, W M Ton. DNA damage and oxidative injury are associated with hypomyelination in the corpus callosum of newborn Nbn(CNS-del) mice. Journal of neuroscience research. vol 92. issue 2. 2014-08-18. PMID:24272991. |
here we first report that nbn gene inactivation induces the defective proliferation and enhanced apoptosis of the oligodendrocyte precursor cells (opcs), contributing to the severe hypomyelination of the nerve fibers of the corpus callosum. |
2014-08-18 |
2023-08-12 |
mouse |
| Dipankar J Dutta, Andleeb Zameer, John N Mariani, Jingya Zhang, Linnea Asp, Jimmy Huynh, Sean Mahase, Benjamin M Laitman, Azeb Tadesse Argaw, Nesanet Mitiku, Mateusz Urbanski, Carmen V Melendez-Vasquez, Patrizia Casaccia, Fernand Hayot, Erwin P Bottinger, Chester W Brown, Gareth R Joh. Combinatorial actions of Tgfβ and Activin ligands promote oligodendrocyte development and CNS myelination. Development (Cambridge, England). vol 141. issue 12. 2014-08-08. PMID:24917498. |
in spinal cords of actb-deficient inhbb(-/-) embryos, apoptosis in the oligodendrocyte lineage is increased and olp numbers transiently reduced, but numbers, maturation and myelination recover during the first postnatal week. |
2014-08-08 |
2023-08-13 |
mouse |
| Yi Ren, Wise Youn. Managing inflammation after spinal cord injury through manipulation of macrophage function. Neural plasticity. vol 2013. 2014-07-22. PMID:24288627. |
spinal cord injury (sci) triggers inflammation with activation of innate immune responses that contribute to secondary injury including oligodendrocyte apoptosis, demyelination, axonal degeneration, and neuronal death. |
2014-07-22 |
2023-08-12 |
Not clear |
| Johannes Goldberg, Moritz Daniel, Yasemin van Heuvel, Marion Victor, Cordian Beyer, Tim Clarner, Markus Kip. Short-term cuprizone feeding induces selective amino acid deprivation with concomitant activation of an integrated stress response in oligodendrocytes. Cellular and molecular neurobiology. vol 33. issue 8. 2014-07-08. PMID:23979168. |
in this model, mice are fed with the copper chelator cuprizone which leads to oligodendrocyte apoptosis and subsequent microgliosis, astrocytosis, and demyelination. |
2014-07-08 |
2023-08-12 |
mouse |
| Johannes Goldberg, Moritz Daniel, Yasemin van Heuvel, Marion Victor, Cordian Beyer, Tim Clarner, Markus Kip. Short-term cuprizone feeding induces selective amino acid deprivation with concomitant activation of an integrated stress response in oligodendrocytes. Cellular and molecular neurobiology. vol 33. issue 8. 2014-07-08. PMID:23979168. |
these parameters were paralleled by oligodendrocyte apoptosis and the induction of an aar with increased expression of the transcription factors atf-3 and atf-4 (activating transcription factor-3 and -4). |
2014-07-08 |
2023-08-12 |
mouse |
| Jessica L Fletcher, Gauthami S Kondagari, Charles H Vite, Peter Williamson, Rosanne M Taylo. Oligodendrocyte loss during the disease course in a canine model of the lysosomal storage disease fucosidosis. Journal of neuropathology and experimental neurology. vol 73. issue 6. 2014-06-30. PMID:24806306. |
despite progressive vacuolation, mature oligodendrocyte loss by apoptosis (caspase-6 positive) in the corpus callosum and cerebellar white matter stabilized by 16 weeks, with no further subsequent loss. |
2014-06-30 |
2023-08-13 |
Not clear |
| Jessica L Fletcher, Gauthami S Kondagari, Charles H Vite, Peter Williamson, Rosanne M Taylo. Oligodendrocyte loss during the disease course in a canine model of the lysosomal storage disease fucosidosis. Journal of neuropathology and experimental neurology. vol 73. issue 6. 2014-06-30. PMID:24806306. |
a 67% decline in the number of purkinje cell layer oligodendrocytes coincided with a 67% increase in the number of caspase-6-positive purkinje cells at 16 weeks, suggesting that early oligodendrocyte loss contributes to purkinje cell apoptosis. |
2014-06-30 |
2023-08-13 |
Not clear |
| Madhuvika Murugan, Eng-Ang Ling, Charanjit Kau. Dysregulated glutamate uptake by astrocytes causes oligodendroglia death in hypoxic perventricular white matter damage. Molecular and cellular neurosciences. vol 56. 2014-06-20. PMID:23859823. |
we sought to examine if hypoxia altered the expression of astroglial excitatory amino acid transporters (eaat1, eaat2 and eaat3) in the pwm, and, if so, whether it activated astroglial n-methyl d-aspartate receptors (nmdar) which might lead to apoptosis of oligodendroglia. |
2014-06-20 |
2023-08-12 |
rat |
| Madhuvika Murugan, Eng-Ang Ling, Charanjit Kau. Dysregulated glutamate uptake by astrocytes causes oligodendroglia death in hypoxic perventricular white matter damage. Molecular and cellular neurosciences. vol 56. 2014-06-20. PMID:23859823. |
following hypoxia, an increase in gap junction proteins between astroglia and oligodendroglia aided in the spreading of nmdar-mediated excitotoxic calcium signals into the latter cell type triggering its apoptosis. |
2014-06-20 |
2023-08-12 |
rat |
| Sujata Saraswat Ohri, Michal Hetman, Scott R Whittemor. Restoring endoplasmic reticulum homeostasis improves functional recovery after spinal cord injury. Neurobiology of disease. vol 58. 2014-04-23. PMID:23659896. |
this improved functional recovery corresponded with increased white matter sparing and decreased oligodendrocyte apoptosis. |
2014-04-23 |
2023-08-12 |
mouse |
| Małgorzata Juszczak, Katarzyna Walczak, Ewa Langner, Monika Karpińska, Joanna Matysiak, Wojciech Rzesk. Neuroprotective activity of 2-amino-1,3,4-thiadiazole derivative 4BrABT--an in vitro study. Annals of agricultural and environmental medicine : AAEM. vol 20. issue 3. 2014-04-21. PMID:24069868. |
moreover, 4brabt ability to prevent the cisplatin-induced apoptosis in astrocyte and oligodendrocyte cultures was analysed after hoechst 33342 fluorostaining. |
2014-04-21 |
2023-08-12 |
mouse |
| Fanglin Zhang, Song-Yi Yao, William O Whetsell, Subramaniam Srira. Astrogliopathy and oligodendrogliopathy are early events in CNS demyelination. Glia. vol 61. issue 8. 2014-03-10. PMID:23832594. |
we believe that the innate immune model of oligodendrocyte death will be useful in the development of neuroprotective agents capable of rescuing oligodendrocytes from apoptosis. |
2014-03-10 |
2023-08-12 |
rat |
| Tan Li, Wenbin Wang, Yung-Wei Pan, Lihong Xu, Zhengui Xi. A hydroxylated metabolite of flame-retardant PBDE-47 decreases the survival, proliferation, and neuronal differentiation of primary cultured adult neural stem cells and interferes with signaling of ERK5 MAP kinase and neurotrophin 3. Toxicological sciences : an official journal of the Society of Toxicology. vol 134. issue 1. 2014-01-28. PMID:23564643. |
interestingly, 6-oh-pbde-47 induced apoptosis at concentrations above 7.5μm inhibited proliferation at 2.5-5μm while suppressing neuronal and oligodendrocyte differentiation at submicromolar concentrations (≤ 1μm). |
2014-01-28 |
2023-08-12 |
mouse |
| J Flygt, A Djupsjö, F Lenne, N Marklun. Myelin loss and oligodendrocyte pathology in white matter tracts following traumatic brain injury in the rat. The European journal of neuroscience. vol 38. issue 1. 2014-01-15. PMID:23458840. |
our results indicate that tbi induces oligodendrocyte apoptosis and widespread myelin loss, followed by a concomitant increase in the number of opcs. |
2014-01-15 |
2023-08-12 |
rat |
| Karolina Kleinsimlinghaus, Romy Marx, Meray Serdar, Ivo Bendix, Irmgard D Dietze. Strategies for repair of white matter: influence of osmolarity and microglia on proliferation and apoptosis of oligodendrocyte precursor cells in different basal culture media. Frontiers in cellular neuroscience. vol 7. 2014-01-14. PMID:24421756. |
strategies for repair of white matter: influence of osmolarity and microglia on proliferation and apoptosis of oligodendrocyte precursor cells in different basal culture media. |
2014-01-14 |
2023-08-12 |
rat |
| Tatsuro Misu, Romana Höftberger, Kazuo Fujihara, Isabella Wimmer, Yoshiki Takai, Shuhei Nishiyama, Ichiro Nakashima, Hidehiko Konno, Monika Bradl, Ferenc Garzuly, Yasuto Itoyama, Masashi Aoki, Hans Lassman. Presence of six different lesion types suggests diverse mechanisms of tissue injury in neuromyelitis optica. Acta neuropathologica. vol 125. issue 6. 2013-12-03. PMID:23579868. |
finally, lesions with a variable degree of astrocyte clasmatodendrosis are found, which show plaque-like primary demyelination that is associated with oligodendrocyte apoptosis, but with preservation of axons (lesion type 6). |
2013-12-03 |
2023-08-12 |
Not clear |