| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Acs, M A Selak, S Komoly, B Kalma. Distribution of oligodendrocyte loss and mitochondrial toxicity in the cuprizone-induced experimental demyelination model. Journal of neuroimmunology. vol 262. issue 1-2. 2013-11-18. PMID:23890807. |
cuprizone is a copper-chelating mitochondrial toxin that causes oligodendrocyte apoptosis and demyelination preferentially in the corpus callosum (cc) and the superior cerebellar peduncles, but not in the spinal cord (sc) of c57bl/6 mice. |
2013-11-18 |
2023-08-12 |
mouse |
| Jong-Wan Kim, Young J Kim, Young P Chan. Administration of dexamethasone to neonatal rats induces hypomyelination and changes in the morphology of oligodendrocyte precursors. Comparative medicine. vol 63. issue 1. 2013-10-17. PMID:23561937. |
to examine whether hypomyelination in neonatal rats might be related to apoptosis of oligodendrocyte progenitors, we administered dexamethasone (0.5 mg/kg sc) to neonatal rats on postnatal (p) days 1 through 5. |
2013-10-17 |
2023-08-12 |
rat |
| Jong-Wan Kim, Young J Kim, Young P Chan. Administration of dexamethasone to neonatal rats induces hypomyelination and changes in the morphology of oligodendrocyte precursors. Comparative medicine. vol 63. issue 1. 2013-10-17. PMID:23561937. |
administration of dexamethasone during the critical period of brain development may increase the risk of apoptosis in oligodendrocyte progenitors, subsequently resulting in hypomyelination. |
2013-10-17 |
2023-08-12 |
rat |
| M Mecha, A S Torrao, L Mestre, F J Carrillo-Salinas, R Mechoulam, C Guaz. Cannabidiol protects oligodendrocyte progenitor cells from inflammation-induced apoptosis by attenuating endoplasmic reticulum stress. Cell death & disease. vol 3. 2013-07-23. PMID:22739983. |
cannabidiol protects oligodendrocyte progenitor cells from inflammation-induced apoptosis by attenuating endoplasmic reticulum stress. |
2013-07-23 |
2023-08-12 |
Not clear |
| Geeta Ramesh, Shemi Benge, Bapi Pahar, Mario T Philip. A possible role for inflammation in mediating apoptosis of oligodendrocytes as induced by the Lyme disease spirochete Borrelia burgdorferi. Journal of neuroinflammation. vol 9. 2013-06-10. PMID:22524232. |
earlier we demonstrated that interaction of b. burgdorferi with brain parenchyma induces inflammatory mediators in glial cells as well as glial (oligodendrocyte) and neuronal apoptosis using ex vivo and in vivo models of experimentation. |
2013-06-10 |
2023-08-12 |
Not clear |
| Yee Andy Yeo, Julia M Martínez Gómez, J Ludovic Croxford, Stephan Gasser, Eng-Ang Ling, Herbert Schwar. CD137 ligand activated microglia induces oligodendrocyte apoptosis via reactive oxygen species. Journal of neuroinflammation. vol 9. 2013-06-10. PMID:22799524. |
cd137 ligand activated microglia induces oligodendrocyte apoptosis via reactive oxygen species. |
2013-06-10 |
2023-08-12 |
mouse |
| Lan-Wan Wang, Yi-Fang Tu, Chao-Ching Huang, Chien-Jung H. JNK signaling is the shared pathway linking neuroinflammation, blood-brain barrier disruption, and oligodendroglial apoptosis in the white matter injury of the immature brain. Journal of neuroinflammation. vol 9. 2013-06-10. PMID:22805152. |
neuroinflammation, blood-brain barrier (bbb) damage and oligodendrocyte progenitor apoptosis may affect the susceptibility of lps-sensitized hi in white matter injury. |
2013-06-10 |
2023-08-12 |
rat |
| Emanuele Tirotta, Leslie A Kirby, Maya N Hatch, Thomas E Lan. IFN-γ-induced apoptosis of human embryonic stem cell derived oligodendrocyte progenitor cells is restricted by CXCR2 signaling. Stem cell research. vol 9. issue 3. 2013-05-30. PMID:22885102. |
ifn-γ-induced apoptosis of human embryonic stem cell derived oligodendrocyte progenitor cells is restricted by cxcr2 signaling. |
2013-05-30 |
2023-08-12 |
human |
| Wensheng Lin, Yifeng Lin, Jin Li, Ali G Fenstermaker, Sharon W Way, Benjamin Clayton, Stephanie Jamison, Heather P Harding, David Ron, Brian Popk. Oligodendrocyte-specific activation of PERK signaling protects mice against experimental autoimmune encephalomyelitis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 14. 2013-05-28. PMID:23554479. |
there is compelling evidence that oligodendrocyte apoptosis, in response to cns inflammation, contributes significantly to the development of the demyelinating disorder multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis (eae). |
2013-05-28 |
2023-08-12 |
mouse |
| Wensheng Lin, Yifeng Lin, Jin Li, Ali G Fenstermaker, Sharon W Way, Benjamin Clayton, Stephanie Jamison, Heather P Harding, David Ron, Brian Popk. Oligodendrocyte-specific activation of PERK signaling protects mice against experimental autoimmune encephalomyelitis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 14. 2013-05-28. PMID:23554479. |
importantly, we found that enhanced activation of perk signaling specifically in oligodendrocytes significantly attenuated eae disease severity, which was associated with reduced oligodendrocyte apoptosis, demyelination, and axonal degeneration. |
2013-05-28 |
2023-08-12 |
mouse |
| Nan Zhang, Tingguo Kang, Yang Xia, Qingping Wen, Xiaodan Zhang, Hongyan Li, Yv Hu, Haiguang Hao, Dan Zhao, Dong Sun, Yaping Yan, Guang-Xian Zhang, Jingxian Yan. Effects of salvianolic acid B on survival, self-renewal and neuronal differentiation of bone marrow derived neural stem cells. European journal of pharmacology. vol 697. issue 1-3. 2013-05-02. PMID:23085027. |
here, we demonstrate that salvianolic acid b (sal b), a potent aqueous of a well known chinese medicine herb, salvia miltiorrhiza, possesses the ability to promote bm-nscs proliferation in a dose dependent manner as verified by growth curve and bromodeoxyuridine (brdu) incorporation assays; while in differentiation medium, sal b promoted nestin(+) bm-nscs differentiated into greater numbers of nf-m(+) neurons and ng2(+) oligodendrocyte precursors, but fewer gfap(+) astrocytes as verified by triple immunostaining and quantitative analysis; upon exposure to h(2)o(2), sal b facilitated the cells survival, reduced ldh leakage, and inhibited apoptosis, displaying a dose-dependent neuroprotective effect on bm-nscs. |
2013-05-02 |
2023-08-12 |
Not clear |
| Chongchong Xu, Lei Lv, Guoli Zheng, Beiya Li, Lu Gao, Yan Su. Neuregulin1β1 protects oligodendrocyte progenitor cells from oxygen glucose deprivation injury induced apoptosis via ErbB4-dependent activation of PI3-kinase/Akt. Brain research. vol 1467. 2012-11-20. PMID:22659027. |
neuregulin1β1 protects oligodendrocyte progenitor cells from oxygen glucose deprivation injury induced apoptosis via erbb4-dependent activation of pi3-kinase/akt. |
2012-11-20 |
2023-08-12 |
Not clear |
| Péter Acs, Sámuel Komol. Selective ultrastructural vulnerability in the cuprizone-induced experimental demyelination. Ideggyogyaszati szemle. vol 65. issue 7-8. 2012-11-13. PMID:23074847. |
however, the exact pathomechanism that lead to oligodendrocyte apoptosis in human demyelinating diseases is still elusive. |
2012-11-13 |
2023-08-12 |
mouse |
| Péter Acs, Sámuel Komol. Selective ultrastructural vulnerability in the cuprizone-induced experimental demyelination. Ideggyogyaszati szemle. vol 65. issue 7-8. 2012-11-13. PMID:23074847. |
the copper chelator cuprizone induces primary oligodendrocyte apoptosis and consequent demyelination in well defined areas of the mouse brain. |
2012-11-13 |
2023-08-12 |
mouse |
| Péter Acs, Sámuel Komol. Selective ultrastructural vulnerability in the cuprizone-induced experimental demyelination. Ideggyogyaszati szemle. vol 65. issue 7-8. 2012-11-13. PMID:23074847. |
we aimed to study the ultrastructural alterations that might induce oligodendrocyte apoptosis in the cuprizone experimental demyelination model. |
2012-11-13 |
2023-08-12 |
mouse |
| John W Prineas, John D E Parrat. Oligodendrocytes and the early multiple sclerosis lesion. Annals of neurology. vol 72. issue 1. 2012-10-24. PMID:22829266. |
these similarities raise the possibility that like nmo, ms is an autoimmune disease in which oligodendrocyte apoptosis is determined by injury to some other glial or mesenchymal component. |
2012-10-24 |
2023-08-12 |
Not clear |
| Wataru Yamaguchi, Rie Tamai, Miho Kageura, Tatsuo Furuyama, Shinobu Inagak. Sema4D as an inhibitory regulator in oligodendrocyte development. Molecular and cellular neurosciences. vol 49. issue 3. 2012-07-13. PMID:22198439. |
thus, sema4d may act as an intrinsic inhibitory regulator of oligodendrocyte differentiation by promoting apoptosis. |
2012-07-13 |
2023-08-12 |
mouse |
| Ke-Bing Chen, Kenzo Uchida, Hideaki Nakajima, Takafumi Yayama, Takayuki Hirai, Shuji Watanabe, Alexander Rodriguez Guerrero, Shigeru Kobayashi, Wei-Ying Ma, Shao-Yu Liu, Hisatoshi Bab. Tumor necrosis factor-α antagonist reduces apoptosis of neurons and oligodendroglia in rat spinal cord injury. Spine. vol 36. issue 17. 2012-05-31. PMID:21224756. |
tumor necrosis factor-α antagonist reduces apoptosis of neurons and oligodendroglia in rat spinal cord injury. |
2012-05-31 |
2023-08-12 |
rat |
| Sara Palumbo, Christopher D Toscano, Laura Parente, Roberto Weigert, Francesca Bosett. The cyclooxygenase-2 pathway via the PGE₂ EP2 receptor contributes to oligodendrocytes apoptosis in cuprizone-induced demyelination. Journal of neurochemistry. vol 121. issue 3. 2012-05-24. PMID:21699540. |
in cuprizone-induced demyelination, oligodendrocyte apoptosis and a concomitant increase in the gene expression of cox-2 and pge₂-ep2 receptor precede histological demyelination. |
2012-05-24 |
2023-08-12 |
Not clear |
| Sara Palumbo, Christopher D Toscano, Laura Parente, Roberto Weigert, Francesca Bosett. The cyclooxygenase-2 pathway via the PGE₂ EP2 receptor contributes to oligodendrocytes apoptosis in cuprizone-induced demyelination. Journal of neurochemistry. vol 121. issue 3. 2012-05-24. PMID:21699540. |
cox-2 gene deletion, chronic treatment with the cox-2 selective inhibitor celecoxib, or with the ep2 receptor antagonist ah6809 reduced cuprizone-induced oligodendrocyte apoptosis, the degree of demyelination and motor dysfunction. |
2012-05-24 |
2023-08-12 |
Not clear |