| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B S Tea, T V Dam, P Moreau, P Hamet, D deBloi. Apoptosis during regression of cardiac hypertrophy in spontaneously hypertensive rats. Temporal regulation and spatial heterogeneity. Hypertension (Dallas, Tex. : 1979). vol 34. issue 2. 1999-09-15. PMID:10454446. |
thus, transient induction of apoptosis in the subepicardium appears to be a characteristic feature of the early response to drug-induced regression of cardiac hypertrophy in spontaneously hypertensive rats. |
1999-09-15 |
2023-08-12 |
rat |
| D A Siwik, J D Tzortzis, D R Pimental, D L Chang, P J Pagano, K Singh, D B Sawyer, W S Colucc. Inhibition of copper-zinc superoxide dismutase induces cell growth, hypertrophic phenotype, and apoptosis in neonatal rat cardiac myocytes in vitro. Circulation research. vol 85. issue 2. 1999-08-12. PMID:10417396. |
inhibition of copper-zinc superoxide dismutase induces cell growth, hypertrophic phenotype, and apoptosis in neonatal rat cardiac myocytes in vitro. |
1999-08-12 |
2023-08-12 |
rat |
| K L Kolaja, A M Hood, C D Klaasse. The UDP-glucuronyltransferase inducers, phenobarbital and pregnenolone-16alpha-carbonitrile, enhance thyroid-follicular cell apoptosis: association with TGF-beta1 expression. Toxicology letters. vol 106. issue 2-3. 1999-07-22. PMID:10403658. |
thus, treatment with udp-gt-inducing chemicals may increase the expression of tgf-beta1 and apoptosis in the thyroid to compensate for the thyroid hypertrophy and hyperplasia. |
1999-07-22 |
2023-08-12 |
rat |
| M A López-González, P Díaz, F Delgado, M Luca. Lack of lymphoid cell apoptosis in the pathogenesis of tonsillar hypertrophy as compared to recurrent tonsillitis. European journal of pediatrics. vol 158. issue 6. 1999-07-14. PMID:10378394. |
lack of lymphoid cell apoptosis in the pathogenesis of tonsillar hypertrophy as compared to recurrent tonsillitis. |
1999-07-14 |
2023-08-12 |
Not clear |
| M A López-González, P Díaz, F Delgado, M Luca. Lack of lymphoid cell apoptosis in the pathogenesis of tonsillar hypertrophy as compared to recurrent tonsillitis. European journal of pediatrics. vol 158. issue 6. 1999-07-14. PMID:10378394. |
in children with tonsillar hypertrophy both parameters were decreased contrasting with those with recurrent tonsillitis where apoptosis is increased. |
1999-07-14 |
2023-08-12 |
Not clear |
| M A López-González, P Díaz, F Delgado, M Luca. Lack of lymphoid cell apoptosis in the pathogenesis of tonsillar hypertrophy as compared to recurrent tonsillitis. European journal of pediatrics. vol 158. issue 6. 1999-07-14. PMID:10378394. |
it may be speculated that the increase of basophils in children with tonsillar hypertrophy results in increased release of interleukin-4, which could prevent lymphoid apoptosis and lead to cell proliferation in tonsillar tissue. |
1999-07-14 |
2023-08-12 |
Not clear |
| N Ashizawa, M Niigaki, N Hamamoto, M Niigaki, T Kaji, T Katsube, S Sato, H Endoh, K Hidaka, M Watanabe, Y Kinoshit. The morphological changes of exocrine pancreas in chronic pancreatitis. Histology and histopathology. vol 14. issue 2. 1999-06-28. PMID:10212816. |
these are considered to be the results of obstructive pancreatitis, which are caused by the reactions of defensive factors against the increase of pancreatic duct pressure, including the apoptosis of acinar cells, the hyperplasia and hypertrophy of duct cells, a tighter junctional complex of duct cells, and periductal fibrosis. |
1999-06-28 |
2023-08-12 |
rat |
| P Hame. What is apoptosis and what is its relevance to vascular biology? The Canadian journal of cardiology. vol 15 Suppl B. 1999-06-16. PMID:10350674. |
increased rates of apoptosis, which occur during limited time windows, have been implicated in animal models of hypertension and cardiac hypertrophy. |
1999-06-16 |
2023-08-12 |
Not clear |
| H Hirota, J Chen, U A Betz, K Rajewsky, Y Gu, J Ross, W Müller, K R Chie. Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress. Cell. vol 97. issue 2. 1999-05-17. PMID:10219240. |
such conditional mutant mice have normal cardiac structure and function, but during aortic pressure overload, these mice display rapid onset of dilated cardiomyopathy and massive induction of myocyte apoptosis versus the control mice that exhibit compensatory hypertrophy. |
1999-05-17 |
2023-08-12 |
mouse |
| H Hirota, J Chen, U A Betz, K Rajewsky, Y Gu, J Ross, W Müller, K R Chie. Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress. Cell. vol 97. issue 2. 1999-05-17. PMID:10219240. |
thus, cardiac myocyte apoptosis is a critical point in the transition between compensatory cardiac hypertrophy and heart failure. |
1999-05-17 |
2023-08-12 |
mouse |
| P G Wylie, R A Challiss, J L Blan. Regulation of extracellular-signal regulated kinase and c-Jun N-terminal kinase by G-protein-linked muscarinic acetylcholine receptors. The Biochemical journal. vol 338 ( Pt 3). 1999-05-04. PMID:10051431. |
extracellular signal-regulated kinases (erks) and c-jun n-terminal kinases (jnks, or stress-activated protein kinases) are activated by diverse extracellular signals and mediate a variety of cellular responses, including mitogenesis, differentiation, hypertrophy, inflammatory reactions and apoptosis. |
1999-05-04 |
2023-08-12 |
human |
| A Leri, Y Liu, X Wang, J Kajstura, A Malhotra, L G Meggs, P Anvers. Overexpression of insulin-like growth factor-1 attenuates the myocyte renin-angiotensin system in transgenic mice. Circulation research. vol 84. issue 7. 1999-04-30. PMID:10205143. |
constitutive overexpression of insulin-like growth factor-1 (igf-1) in myocytes protects them from apoptosis and interferes with myocyte hypertrophy in the normal and pathological heart. |
1999-04-30 |
2023-08-12 |
mouse |
| X Wang, F Gu, B Yan. [Apoptosis in the early stage of compensatory renal growth following uninephrectomy in the young and old rats]. Zhonghua yi xue za zhi. vol 77. issue 10. 1999-04-27. PMID:9772517. |
to investigate the role of apoptosis, one of the major factor to maintain homeostasis of cell number of organs, in the early process of compensatory renal growth, which have been considered to including cellular hyperplasia and hypertrophy, following uninephrectomy. |
1999-04-27 |
2023-08-12 |
rat |
| B Gajkowska, M Smialek, R P Ostrowski, P Piotrowski, M Frontczak-Baniewic. The experimental squalene encephaloneuropathy in the rat. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 51. issue 1. 1999-04-21. PMID:10048717. |
endothelial cells were hypertrophic and a few demonstrated features of apoptosis. |
1999-04-21 |
2023-08-12 |
rat |
| G Silvestrini, P Mocetti, P Ballanti, R Di Grezia, E Bonucc. In vivo incidence of apoptosis evaluated with the TdT FragEL DNA fragmentation detection kit in cartilage and bone cells of the rat tibia. Tissue & cell. vol 30. issue 6. 1999-03-29. PMID:10036787. |
our results confirm that apoptosis does occur in hypertrophic chondrocytes and bone cells, and show that its frequency is very low. |
1999-03-29 |
2023-08-12 |
rat |
| T Szuwart, H Kierdorf, U Kierdorf, G Cleme. Ultrastructural aspects of cartilage formation, mineralization, and degeneration during primary antler growth in fallow deer (Dama dama). Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. vol 180. issue 6. 1999-02-25. PMID:9862029. |
our results further indicate that the hypertrophic chondrocytes of primary antlers eventually undergo apoptosis, thereby providing further evidence that metaplastic conversion of cartilage into bone does not play a role in antler growth. |
1999-02-25 |
2023-08-12 |
Not clear |
| H Watanabe, Y Yamad. Mice lacking link protein develop dwarfism and craniofacial abnormalities. Nature genetics. vol 21. issue 2. 1999-02-25. PMID:9988279. |
reduced indian hedgehog (ihh) expression was observed in prehypertrophic chondrocytes, and apoptosis was inhibited in hypertrophic chondrocytes. |
1999-02-25 |
2023-08-12 |
mouse |
| S Sanders, S S Thorgeirsso. Phenobarbital promotes liver growth in c-myc/TGF-alpha transgenic mice by inducing hypertrophy and inhibiting apoptosis. Carcinogenesis. vol 20. issue 1. 1999-02-18. PMID:9934848. |
phenobarbital promotes liver growth in c-myc/tgf-alpha transgenic mice by inducing hypertrophy and inhibiting apoptosis. |
1999-02-18 |
2023-08-12 |
mouse |
| S Sanders, S S Thorgeirsso. Phenobarbital promotes liver growth in c-myc/TGF-alpha transgenic mice by inducing hypertrophy and inhibiting apoptosis. Carcinogenesis. vol 20. issue 1. 1999-02-18. PMID:9934848. |
we conclude from our data that pb stimulates liver growth in double transgenic c-myc/tgf-alpha mice by induction of liver hypertrophy and inhibition of apoptosis, brought about by both a decrease in signaling through the tgf-beta pathway and an increase in bcl-2. |
1999-02-18 |
2023-08-12 |
mouse |
| G Gibso. Active role of chondrocyte apoptosis in endochondral ossification. Microscopy research and technique. vol 43. issue 2. 1999-01-28. PMID:9823004. |
from observations of key features of apoptosis, including activation of the caspase cascade, changes in mitochondrial function, and expression of apoptosis inhibitors, the commitment of chondrocytes to apoptosis, appears to occur very early in hypertrophic differentiation. |
1999-01-28 |
2023-08-12 |
Not clear |