| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ge Gao, Yang Zhang, Jian Yu, Yu Chen, Daqun Gu, Chaoshi Niu, Xianming Fu, Jianjun We. Long Non-coding RNA MALAT1/microRNA-143/VEGFA Signal Axis Modulates Vascular Endothelial Injury-Induced Intracranial Aneurysm. Nanoscale research letters. vol 15. issue 1. 2020-09-28. PMID:32602008. |
this study suggests that malat1 elevates vegfa expression through competitive binding to mir-143, thereby boosting apoptosis and attenuating viability of vascular endothelial cells in ia. |
2020-09-28 |
2023-08-13 |
rat |
| Jing Gao, Maimaiti Ailifeire, Chenfei Wang, Li Luo, Jie Zhang, Li Yuan, Li Zhang, Xiaolan Li, Minzhe Wan. miR-320/VEGFA axis affects high glucose-induced metabolic memory during human umbilical vein endothelial cell dysfunction in diabetes pathology. Microvascular research. vol 127. 2020-07-20. PMID:31449822. |
mir-320 suppressed the expression of vegfa via direct binding to the 3'-utr of vegfa mrna, therefore suppressing high glucose-induced metabolic memory (** p < 0.01); the effects of mir-320 overexpression on huvecs could be reversed by vegfa overexpression (# p < 0.05, ## p < 0.01), indicating that mir-320/vegfa axis modulates the proliferation, apoptosis, and the angiogenesis capacity of huvecs. |
2020-07-20 |
2023-08-13 |
human |
| Ying Sun, Na An, Jiansheng Li, Jinchan Xia, Yange Tian, Peng Zhao, Xuefang Liu, Haiying Huang, Jianfeng Gao, Xiaoli Zhan. miRNA-206 regulates human pulmonary microvascular endothelial cell apoptosis via targeting in chronic obstructive pulmonary disease. Journal of cellular biochemistry. vol 120. issue 4. 2020-06-24. PMID:30335896. |
overexpression of either notch3 or vegfa attenuated mir-206-induced cell apoptosis in hpmecs. |
2020-06-24 |
2023-08-13 |
human |
| Ying Sun, Na An, Jiansheng Li, Jinchan Xia, Yange Tian, Peng Zhao, Xuefang Liu, Haiying Huang, Jianfeng Gao, Xiaoli Zhan. miRNA-206 regulates human pulmonary microvascular endothelial cell apoptosis via targeting in chronic obstructive pulmonary disease. Journal of cellular biochemistry. vol 120. issue 4. 2020-06-24. PMID:30335896. |
in conclusion, our results showed that mir-206 was upregulated in copd patients and cse-treated hpmecs, promoted cell apoptosis via directly targeting notch3 and vegfa in hpmecs. |
2020-06-24 |
2023-08-13 |
human |
| Jayant Dewangan, Sonal Srivastava, Sakshi Mishra, Aman Divakar, Sadan Kumar, Srikanta Kumar Rat. Salinomycin inhibits breast cancer progression via targeting HIF-1α/VEGF mediated tumor angiogenesis in vitro and in vivo. Biochemical pharmacology. vol 164. 2020-02-12. PMID:31028743. |
sal also suppressed the serum vegfa level in tumor-bearing mice and induced caspase-dependent apoptosis in breast cancer cells. |
2020-02-12 |
2023-08-13 |
mouse |
| Yunsheng Li, Dan Zheng, Liutong Pan, Yuanting Dai, Shasha Cai, Lijin Zhao, HuiPing Zh. Knockdown of TUG1 by shRNA inhibited renal cell carcinoma formation by miR-299-3p/VEGF axis in vitro and in vivo. European journal of pharmacology. vol 860. 2020-01-08. PMID:31310753. |
knockdown of vegfa (si-vegfa) significantly inhibited the proliferation and motility of achn cells, and induced apoptosis. |
2020-01-08 |
2023-08-13 |
Not clear |
| Wenfeng Cao, Youguang Zhao, Liang Wang, Xiaoke Huan. Circ0001429 regulates progression of bladder cancer through binding miR-205-5p and promoting VEGFA expression. Cancer biomarkers : section A of Disease markers. vol 25. issue 1. 2019-11-22. PMID:30909190. |
this study investigates expressions of circ0001429, mir-205-5p and vascular endothelial growth factor (vegfa) in bladder cancer tissues and their effects on the proliferation, migration and apoptosis. |
2019-11-22 |
2023-08-13 |
Not clear |
| Yunhui Qu, Hongtao Liu, Xinquan Lv, Yuqiong Liu, Xiaojuan Wang, Min Zhang, Xiaqing Zhang, Yuenan Li, Qianqian Lou, Shenglei Li, Huixiang L. MicroRNA-16-5p overexpression suppresses proliferation and invasion as well as triggers apoptosis by targeting VEGFA expression in breast carcinoma. Oncotarget. vol 8. issue 42. 2019-11-20. PMID:29069797. |
microrna-16-5p overexpression suppresses proliferation and invasion as well as triggers apoptosis by targeting vegfa expression in breast carcinoma. |
2019-11-20 |
2023-08-13 |
Not clear |
| Wen-Lan Li. MicroRNA-9 inhibits retinal neovascularization in rats with diabetic retinopathy by targeting vascular endothelial growth factor A. Journal of cellular biochemistry. 2019-11-20. PMID:30485520. |
our study demonstrated that mir-9 could inhibit retinal neovascularization of dr and tubule formation, and promote apoptosis in rmecs by targeting vegfa. |
2019-11-20 |
2023-08-13 |
rat |
| I S Abramov, M A Emelyanova, O O Ryabaya, G S Krasnov, A S Zasedatelev, T V Nasedkin. [Somatic Mutations Associated with Metastasis in Acral Melanoma]. Molekuliarnaia biologiia. vol 53. issue 4. 2019-10-04. PMID:31397438. |
somatic mutations were found in genes related to cell division, proliferation, and apoptosis (braf, nras, vav1, gata1, and gcm2); cell adhesion (ctnnd2 and itgb4); angiogenesis (vegfa); and the regulation of energy metabolism (bcs1l). |
2019-10-04 |
2023-08-13 |
Not clear |
| Baizhuo Dong, Bin Zhou, Zhigang Sun, Shengming Huang, Liang Han, Honghua Nie, Guohui Chen, Shibing Liu, Yanna Zhang, Ning Bao, Xiaolong Yang, Hongwei Fen. LncRNA-FENDRR mediates VEGFA to promote the apoptosis of brain microvascular endothelial cells via regulating miR-126 in mice with hypertensive intracerebral hemorrhage. Microcirculation (New York, N.Y. : 1994). vol 25. issue 8. 2019-06-04. PMID:30120860. |
lncrna-fendrr mediates vegfa to promote the apoptosis of brain microvascular endothelial cells via regulating mir-126 in mice with hypertensive intracerebral hemorrhage. |
2019-06-04 |
2023-08-13 |
mouse |
| Carolina Lisi Román, Bárbara Maiztegui, Héctor Del Zotto, Juan José Gagliardino, Luis Emilio Flore. INGAP-PP effects on β-cell mass and function are related to its positive effect on islet angiogenesis and VEGFA production. Molecular and cellular endocrinology. vol 470. 2019-03-22. PMID:29146554. |
normal islets cultured with ingap-pp and vegfa increased insulin and vegfa secretion while apoptosis decreased. |
2019-03-22 |
2023-08-13 |
rat |
| Pouria Samadi, Sahar Saki, Fatemeh Karimi Dermani, Mona Pourjafar, Massoud Saidija. Emerging ways to treat breast cancer: will promises be met? Cellular oncology (Dordrecht). vol 41. issue 6. 2018-12-24. PMID:30259416. |
these components include erbb family members (her1, her2, her3 and her4), ras/mapk pathway components (ras, raf, mek and erk), vegf family members (vegfa, vegfb, vegfc, vegf and pgf), apoptosis and cell cycle regulators (bak, bax, bcl-2, bcl-x, mcl-1 and bcl-w, p53 and pi3k/akt/mtor pathway components) and dna repair pathway components such as brca1. |
2018-12-24 |
2023-08-13 |
Not clear |
| Shuo Chen, Li-Li Wang, Kai-Xuan Sun, Yao Liu, Xue Guan, Zhi-Hong Zong, Yang Zha. LncRNA TDRG1 enhances tumorigenicity in endometrial carcinoma by binding and targeting VEGF-A protein. Biochimica et biophysica acta. Molecular basis of disease. vol 1864. issue 9 Pt B. 2018-12-11. PMID:29920344. |
furthermore, knockdown of vegfa in lncrna tdrg1-overexpressing endometrial carcinoma cells reversed the effects of lncrna tdrg1 on cell proliferation, invasion, migration and apoptosis. |
2018-12-11 |
2023-08-13 |
human |
| Jiao Xu, Tuochen Zheng, Wenli Hong, Haifeng Ye, Chuan Hu, Yuehui Zhen. Mechanism for the Decision of Ovarian Surface Epithelial Stem Cells to Undergo Neo-Oogenesis or Ovarian Tumorigenesis. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 50. issue 1. 2018-11-02. PMID:30336465. |
as well as external factors, including incessant ovulation, gonadotropin and chronicinflammation: frequent ovulation, without long-term dormancy, increases the risk of illness, because repeated rupture and repair at the ovulation site provides an opportunity for the accumulation of genetic aberrations; fsh affects all aspects of ovarian cancer metastasis, such as inhibition of apoptosis, through induction of increased expression of vegfa (vegf) to support tumor growth, promote vascular growth, and possibly alter certain oncogenic pathways, thereby promoting proliferation and invasive phenotypic inflammation contributes to tumorigenesis, which help determine whether oscs undergo neo-oogenesis or ovarian tumorigenesis. |
2018-11-02 |
2023-08-13 |
Not clear |
| Haihong Pu, Qingyuan Zhang, Chunbo Zhao, Lei Shi, Yan Wang, Jingxuan Wang, Minghui Zhan. VEGFA Involves in the Use of Fluvastatin and Zoledronate Against Breast Cancer. Pathology oncology research : POR. vol 24. issue 3. 2018-10-26. PMID:28744693. |
suppression of vegfa inhibited the apoptosis of mda-mb-231 cells. |
2018-10-26 |
2023-08-13 |
Not clear |
| Haihong Pu, Qingyuan Zhang, Chunbo Zhao, Lei Shi, Yan Wang, Jingxuan Wang, Minghui Zhan. VEGFA Involves in the Use of Fluvastatin and Zoledronate Against Breast Cancer. Pathology oncology research : POR. vol 24. issue 3. 2018-10-26. PMID:28744693. |
our results indicate that up-regulation of vegfa may prevent the progression of breast cancer after fluvastatin and zoledronate treatment via inducing cell apoptosis and inhibiting migration and invasion. |
2018-10-26 |
2023-08-13 |
Not clear |
| Kazutoshi Isobe, Atsushi Kakimoto, Tetuo Mikami, Kyohei Kaburaki, Hiroshi Kobayashi, Takahiro Yoshizawa, Yuta Nakano, Takashi Makino, Hajime Otsuka, Go Sano, Keishi Sugino, Susumu Sakamoto, Yujiro Takai, Naobumi Tochigi, Akira Iyoda, Sakae Homm. PD-L1 mRNA expression in EGFR-mutant lung adenocarcinoma. Oncology reports. vol 40. issue 1. 2018-09-27. PMID:29767258. |
correlations of pd-l1 mrna expression with bim, p53 upregulated modular of apoptosis (puma), human epidermal growth factor receptor 2 (her2), mesenchymal-epithelial transition (met), egfr, and vascular endothelial growth factor a (vegfa) were determined. |
2018-09-27 |
2023-08-13 |
human |
| Shijuan Zhan, Chunfeng Wang, Fangqing Yi. MicroRNA-29c inhibits proliferation and promotes apoptosis in non-small cell lung cancer cells by targeting VEGFA. Molecular medicine reports. vol 17. issue 5. 2018-09-13. PMID:29512752. |
microrna-29c inhibits proliferation and promotes apoptosis in non-small cell lung cancer cells by targeting vegfa. |
2018-09-13 |
2023-08-13 |
Not clear |
| Martin Kragl, Rajib Schubert, Haiko Karsjens, Silke Otter, Barbara Bartosinska, Kay Jeruschke, Jürgen Weiss, Chunguang Chen, David Alsteens, Oliver Kuss, Stephan Speier, Daniel Eberhard, Daniel J Müller, Eckhard Lammer. The biomechanical properties of an epithelial tissue determine the location of its vasculature. Nature communications. vol 7. 2018-09-04. PMID:27995929. |
neither alterations in endothelial cell proliferation, apoptosis, morphology, vegfa expression and vegf-a secretion nor 'empty sleeves' of vascular basement membrane are found. |
2018-09-04 |
2023-08-13 |
mouse |