| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuchen Qi, Yinghui Song, Mengting Cai, Jianwen Li, Zhangtao Yu, Yuhang Li, Junkai Huang, Yu Jiang, Chuang Peng, Bo Jiang, Sulai Li. Vascular endothelial growth factor A is a potential prognostic biomarker and correlates with immune cell infiltration in hepatocellular carcinoma. Journal of cellular and molecular medicine. 2023-02-02. PMID:36729917. |
inhibition of vegfa reduces proliferation, invasion, and migration and promotes apoptosis in hcc cells. |
2023-02-02 |
2023-08-14 |
human |
| Yuanyuan Shi, Hua Zhu, Hang Jiang, Hongqin Yue, Fang Yuan, Fusheng Wan. Cancer-associated fibroblasts-derived exosomes from chemoresistant patients regulate cisplatin resistance and angiogenesis by delivering VEGFA in colorectal cancer. Anti-cancer drugs. 2023-02-02. PMID:36730310. |
overexpressed vegfa in r-cafs apparently regulates the viability, apoptosis, ddp resistance, and angiogenesis of crc. |
2023-02-02 |
2023-08-14 |
mouse |
| Yuanyuan Shi, Hua Zhu, Hang Jiang, Hongqin Yue, Fang Yuan, Fusheng Wan. Cancer-associated fibroblasts-derived exosomes from chemoresistant patients regulate cisplatin resistance and angiogenesis by delivering VEGFA in colorectal cancer. Anti-cancer drugs. 2023-02-02. PMID:36730310. |
r-cafs-derived exosomes promote the viability, apoptosis, ddp resistance, and angiogenesis of crc by delivering vegfa. |
2023-02-02 |
2023-08-14 |
mouse |
| Audrey Ziverec, Marie Chanal, Perrine Raymond, Mirela Diana Ilie, Dario De Alcubierre, Arja Pasternack, Olli Ritvos, Gerald Raverot, Philippe Bertolin. Inhibition of activin-signalling reduces the growth of LβT2 gonadotroph pituitary tumours in mouse. Endocrine-related cancer. 2023-01-12. PMID:36633456. |
in-vitro treatment of lt2 cells with sactriib-fc had no effect on cell proliferation or apoptosis, but vegfa expression was inhibited, pointing to a likely paracrine effect of lt2 cells on endothelial cells through activin-mediated vegfa regulation. |
2023-01-12 |
2023-08-14 |
mouse |
| Yu Jiang, Guangying Zheng, Xiantao Su. PRMT5 promotes retinoblastoma development. Human cell. 2022-11-04. PMID:36331723. |
silencing of vegfa in so-rb50 and y79 cells inhibited cell proliferation, angiogenesis, and migration, promoted apoptosis, and suppressed tumor growth in mice. |
2022-11-04 |
2023-08-14 |
mouse |
| Zhenfeng Hu, Lei Zhuo, Yanling Li, Dongpeng Duan, Jing Gu. MicroRNA‑203a‑3p suppresses endothelial cell proliferation and invasion, and promotes apoptosis in hemangioma by inactivating the VEGF‑mediated PI3K/AKT pathway. Experimental and therapeutic medicine. vol 24. issue 5. 2022-10-24. PMID:36277151. |
vegfa overexpression alone increased cell proliferation and invasion, but decreased apoptosis. |
2022-10-24 |
2023-08-14 |
human |
| Zhenfeng Hu, Lei Zhuo, Yanling Li, Dongpeng Duan, Jing Gu. MicroRNA‑203a‑3p suppresses endothelial cell proliferation and invasion, and promotes apoptosis in hemangioma by inactivating the VEGF‑mediated PI3K/AKT pathway. Experimental and therapeutic medicine. vol 24. issue 5. 2022-10-24. PMID:36277151. |
in conclusion, these data suggested that mir-203a-3p may inhibit endothelial cell proliferation and invasion, and promote apoptosis by inactivating vegfa and pi3k/akt signaling in hemangioma. |
2022-10-24 |
2023-08-14 |
human |
| Jiaxuan Tang, Chaofan Liu, Shiying Liu, Xing Zhou, Jinghao Lu, Ming Li, Lubing Zh. Inhibition of JAK1/STAT3 pathway by 2-methoxyestradiol ameliorates psoriatic features in vitro and in an imiquimod-induced psoriasis-like mouse model. European journal of pharmacology. 2022-09-21. PMID:36130639. |
the effects of 2-me on the proliferation, apoptosis, cell cycle, vascular endothelial growth factor a (vegfa), and janus kinase (jak)-signal transducer and activator of transcription (stat) pathways of hacat cells stimulated by interleukin-17 (il-17a) were detected, together with its effect on the proliferation, tube formation and vegf receptor expression of human umbilical vein endothelial cells (huvecs). |
2022-09-21 |
2023-08-14 |
mouse |
| Margarita L Martinez-Fierro, Idalia Garza-Veloz, Maria Eugenia Castañeda-Lopez, Dorothy Wasike, Claudia Castruita-De la Rosa, Iram Pablo Rodriguez-Sanchez, Ivan Delgado-Enciso, Jose Flores-Mendoz. Evaluation of the Effect of the Fibroblast Growth Factor Type 2 (FGF-2) Administration on Placental Gene Expression in a Murine Model of Preeclampsia Induced by L-NAME. International journal of molecular sciences. vol 23. issue 17. 2022-09-09. PMID:36077527. |
in this study, we aimed to determine the effect of fgf2 administration on the placental gene expression of the vascular endothelial growth factor (vegfa), vegf receptor 2 (vegfr2), placental growth factor, endoglin (eng), superoxide dismutase 1 (sod1), catalase (cat), thioredoxin (txn), tumor protein p53 (p53), bcl2 apoptosis regulator, fas cell surface death receptor (fas), and caspase 3, in a sprague dawley rat pe model, which was induced by l-name. |
2022-09-09 |
2023-08-14 |
rat |
| Miyuki Murata, Kousuke Noda, Satoru Kase, Keitaro Hase, Di Wu, Ryo Ando, Susumu Ishid. Placental growth factor stabilizes VEGF receptor-2 protein in retinal pigment epithelial cells by downregulating glycogen synthase kinase 3 activity. The Journal of biological chemistry. 2022-08-15. PMID:35970387. |
we show vegfa reduced apoptosis induced by serum starvation in rpe cells, while the anti-apoptotic effect of vegfa was abrogated by vegfr-2 knockdown. |
2022-08-15 |
2023-08-14 |
Not clear |
| Can Cao, Yuling Zhou, Yu Zhang, Yucong Ma, Shujin Du, Lijie Fan, Ruobing Niu, Yingmei Zhang, Ming H. GCN5 participates in KLF4-VEGFA feedback to promote endometrial angiogenesis. iScience. vol 25. issue 7. 2022-06-23. PMID:35733790. |
here we found that vascular endothelial growth factor a (vegfa) can form a positive feedback loop with klf4 to promote the proliferation and migration of human endometrial microvascular endothelial cells (hemecs) and inhibit cell apoptosis. |
2022-06-23 |
2023-08-14 |
human |
| Dingmei Deng, Xian Ye, Xiyue Wang, Guangning H. Retracted Article: Gemcitabine aggravates miR-199a-5p-mediated breast cancer cell apoptosis by promoting VEGFA downregulation RSC advances. vol 9. issue 35. 2022-05-06. PMID:35514680. |
retracted article: gemcitabine aggravates mir-199a-5p-mediated breast cancer cell apoptosis by promoting vegfa downregulation breast cancer is the most frequent malignancy diagnosed in women, and gemcitabine-based therapy is frequently used to treat late-stage breast cancer. |
2022-05-06 |
2023-08-13 |
Not clear |
| Laura Fishe. Retraction: Gemcitabine aggravates miR-199a-5p-mediated breast cancer cell apoptosis by promoting VEGFA downregulation RSC advances. vol 11. issue 27. 2022-04-28. PMID:35481960. |
retraction: gemcitabine aggravates mir-199a-5p-mediated breast cancer cell apoptosis by promoting vegfa downregulation [this retracts the article doi: 10.1039/c9ra00016j. |
2022-04-28 |
2023-08-13 |
Not clear |
| Youzi Dong, Quanlin Zhao, Yuguo Wan. Network pharmacology-based investigation of potential targets of astragalus membranaceous-angelica sinensis compound acting on diabetic nephropathy. Scientific reports. vol 11. issue 1. 2021-12-08. PMID:34593896. |
am-as compound may treat dn by acting on vegfa, tp53, il-6, tnf, mark1, etc., and regulate apoptosis, oxidative stress, inflammation, glucose, and lipid metabolism processes. |
2021-12-08 |
2023-08-13 |
rat |
| Darko Maric, Aleksandra Paterek, Marion Delaunay, Irene Pérez López, Miroslav Arambasic, Dario Divian. A-Kinase Anchoring Protein 2 Promotes Protection against Myocardial Infarction. Cells. vol 10. issue 11. 2021-12-08. PMID:34831084. |
this results in the upregulation of er-dependent genes involved in protection against apoptosis and angiogenesis, including bcl2 and the vascular endothelial growth factor a (vegfa). |
2021-12-08 |
2023-08-13 |
mouse |
| Darko Maric, Aleksandra Paterek, Marion Delaunay, Irene Pérez López, Miroslav Arambasic, Dario Divian. A-Kinase Anchoring Protein 2 Promotes Protection against Myocardial Infarction. Cells. vol 10. issue 11. 2021-12-08. PMID:34831084. |
in line with these findings, cardiomyocyte-specific akap2 ko reduces bcl2 and vegfa expression, increases myocardial apoptosis and impairs the formation of new blood vessels in infarcted hearts. |
2021-12-08 |
2023-08-13 |
mouse |
| Yu-Rui Duan, Bao-Ping Chen, Fang Chen, Su-Xia Yang, Chao-Yang Zhu, Ya-Li Ma, Yang Li, Jun Sh. Exosomal microRNA-16-5p from human urine-derived stem cells ameliorates diabetic nephropathy through protection of podocyte. Journal of cellular and molecular medicine. vol 25. issue 23. 2021-12-06. PMID:31568645. |
taken together, the present study revealed that overexpressed mir-16-5p in husc exosomes could protect hpdcs induced by hg and suppress vegfa expression and podocytic apoptosis, providing fresh insights for novel treatment of dn. |
2021-12-06 |
2023-08-13 |
human |
| Yung-Che Chen, Po-Yuan Hsu, Mao-Chang Su, Ting-Wen Chen, Chang-Chun Hsiao, Chien-Hung Chin, Chia-Wei Liou, Po-Wen Wang, Ting-Ya Wang, Yong-Yong Lin, Chiu-Ping Lee, Meng-Chih Li. MicroRNA Sequencing Analysis in Obstructive Sleep Apnea and Depression: Anti-Oxidant and MAOA-Inhibiting Effects of miR-15b-5p and miR-92b-3p through Targeting PTGS1-NF-κB-SP1 Signaling. Antioxidants (Basel, Switzerland). vol 10. issue 11. 2021-11-30. PMID:34829725. |
transfection with mir-15b-5p/mir-92b-3p mimic in vitro reversed ihr-induced early apoptosis, reactive oxygen species production, maoa hyperactivity, and up-regulations of their predicted target genes, including ptgs1, adrb1, gabrb2, garg1, lep, tnfsf13b, vegfa, and cxcl5. |
2021-11-30 |
2023-08-13 |
human |
| Tiantian Zhao, Qingsong Jin, Lili Kong, Dongdong Zhang, Yaqin Teng, Liangyan Lin, Xiaoyan Yao, Yongjun Jin, Minglong L. microRNA-15b-5p shuttled by mesenchymal stem cell-derived extracellular vesicles protects podocytes from diabetic nephropathy via downregulation of VEGF/PDK4 axis. Journal of bioenergetics and biomembranes. 2021-11-22. PMID:34806156. |
inhibition of pdk4 decreased vegfa expression and reduced apoptosis and inflammation. |
2021-11-22 |
2023-08-13 |
mouse |
| Jun Zhou, Yinghao Yin, Yuan Yang, Dongyi Peng, Jingchao Wei, Guangming Yin, Yuxin Tan. Knockdown of miR-423-5p simultaneously upgrades the eNOS and VEGFa pathways in ADSCs and improves erectile function in diabetic rats. Journal of cellular and molecular medicine. vol 25. issue 20. 2021-11-16. PMID:34545676. |
the supernatant and huvecs were collected for assessment of enos and vegfa expression, cell proliferation, and apoptosis. |
2021-11-16 |
2023-08-13 |
human |