| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fan-Chang Zeng, Ming-Qiang Zeng, Liang Huang, Yong-Lin Li, Ben-Min Gao, Jun-Jie Chen, Rui-Zhi Xue, Zheng-Yan Tan. Downregulation of VEGFA inhibits proliferation, promotes apoptosis, and suppresses migration and invasion of renal clear cell carcinoma. OncoTargets and therapy. vol 9. 2016-04-25. PMID:27110129. |
the aim of this study was to investigate the effects of vascular endothelial growth factor a (vegfa) on cell proliferation, apoptosis, migration, and invasion in renal clear cell carcinoma (rccc). |
2016-04-25 |
2023-08-13 |
Not clear |
| Zhuoli Zhu, Xueqi Gan, Hongyi Fan, Haiyang Y. Mechanical stretch endows mesenchymal stem cells stronger angiogenic and anti-apoptotic capacities via NFκB activation. Biochemical and biophysical research communications. vol 468. issue 4. 2016-04-21. PMID:26545780. |
consistent with the increase vegfa expression and resistance to apoptosis, nuclear localization of nfκb activity p65 increased upon mechanical stretch. |
2016-04-21 |
2023-08-13 |
Not clear |
| Bo Zhang, Yangzong Qiangba, Peng Shang, Yunfeng Lu, Yuzeng Yang, Zhixiu Wang, Hao Zhan. Gene expression of vascular endothelial growth factor A and hypoxic adaptation in Tibetan pig. Journal of animal science and biotechnology. vol 7. 2016-04-04. PMID:27042296. |
vascular endothelial growth factor a (vegfa) can induce endothelial cell proliferation, promote cell migration, and inhibit apoptosis. |
2016-04-04 |
2023-08-13 |
Not clear |
| Xin Ma, Donglai Shen, Hongzhao Li, Yu Zhang, Xiangjun Lv, Qingbo Huang, Yu Gao, Xintao Li, Liangyou Gu, Shaoxi Xiu, Xu Bao, Junyao Duan, Xu Zhan. MicroRNA-185 inhibits cell proliferation and induces cell apoptosis by targeting VEGFA directly in von Hippel-Lindau-inactivated clear cell renal cell carcinoma. Urologic oncology. vol 33. issue 4. 2016-02-26. PMID:25700976. |
microrna-185 inhibits cell proliferation and induces cell apoptosis by targeting vegfa directly in von hippel-lindau-inactivated clear cell renal cell carcinoma. |
2016-02-26 |
2023-08-13 |
Not clear |
| Syeda Kiran Riaz, Yasmeen Iqbal, Muhammad Faraz Arshad Mali. Diagnostic and therapeutic implications of the vascular endothelial growth factor family in cancer. Asian Pacific journal of cancer prevention : APJCP. vol 16. issue 5. 2016-01-26. PMID:25773809. |
members included in this group are vegfa, vegfb, vegfc, pigf and vegfd which markedly influence cellular growth and apoptosis. |
2016-01-26 |
2023-08-13 |
Not clear |
| Desheng Fu, Xiaofeng Tia. Effect of high mobility group box 1 on the human retinal pigment epithelial cell in high-glucose condition. International journal of clinical and experimental medicine. vol 8. issue 10. 2016-01-15. PMID:26770371. |
in conclusion, we have demonstrated that hmgb1 and vegfa are key players in the ability to suppress cell viability and induce apoptosis. |
2016-01-15 |
2023-08-13 |
human |
| M Kere, C Siriboon, J W Liao, N W Lo, H I Chiang, Y K Fan, J P Kastelic, J C J. Vascular endothelial growth factor A improves quality of matured porcine oocytes and developing parthenotes. Domestic animal endocrinology. vol 49. 2015-05-15. PMID:25061966. |
adding 5 ng/ml vegfa to oocytes during the last 22 h of in vitro maturation improved (p < 0.05) blastocyst rates and total numbers of cells, with reduced apoptosis indices similar to that of long-term (44 h) culture. |
2015-05-15 |
2023-08-13 |
human |
| L Geng, A Chaudhuri, G Talmon, J L Wisecarver, C Are, M Brattain, J Wan. MicroRNA-192 suppresses liver metastasis of colon cancer. Oncogene. vol 33. issue 46. 2015-01-28. PMID:24213572. |
further studies indicate that mir-192 downregulates expression of bcl-2, zeb2 and vegfa in vitro and in vivo, which is responsible for enhanced apoptosis, increased expression of e-cadherin and decreased angiogenesis in vivo, respectively. |
2015-01-28 |
2023-08-12 |
mouse |
| Yolanda Espinosa-Parrilla, Xavier Muñoz, Catalina Bonet, Nadia Garcia, Adoración Venceslá, Nikos Yiannakouris, Alessio Naccarati, Sabina Sieri, Salvatore Panico, José M Huerta, Aurelio Barricarte, Virginia Menéndez, Emilio Sánchez-Cantalejo, Miren Dorronsoro, Paul Brennan, Talita Duarte-Salles, H B As Bueno-de-Mesquita, Elisabete Weiderpass, Eiliv Lund, Françoise Clavel-Chapelon, Marie-Christine Boutron-Ruault, Antoine Racine, Mattijs E Numans, Rosario Tumino, Federico Canzian, Daniele Campa, Malin Sund, Mattias Johansson, Bodil Ohlsson, Björn Lindkvist, Kim Overvad, Anne Tjønneland, Domenico Palli, Ruth C Travis, Kay-Tee Khaw, Nick Wareham, Heiner Boeing, Gabriella Nesi, Elio Riboli, Carlos A Gonzalez, Núria Sal. Genetic association of gastric cancer with miRNA clusters including the cancer-related genes MIR29, MIR25, MIR93 and MIR106: results from the EPIC-EURGAST study. International journal of cancer. vol 135. issue 9. 2014-10-21. PMID:24643999. |
some functionally validated target genes of these mirnas are implicated in cancer-related processes such as methylation (dnmt3a, dnmt3b), cell cycle (e2f1, cdkn1a, cdkn1c), apoptosis (bcl2l11, mcl1), angiogenesis (vegfa) and progression (pik3r1, mycn). |
2014-10-21 |
2023-08-12 |
Not clear |
| N Ally, X L Zou, B C Jiang, L Qin, L Zhai, P Xiao, H L Li. Inhibition of vascular endothelial growth factor A expression in mouse granulosa cells by lentivector-mediated RNAi. Genetics and molecular research : GMR. vol 11. issue 4. 2013-03-27. PMID:23212339. |
vegfa gene expression, apoptosis genes and vegfa receptor genes were detected by qrt-pcr, the vegfa protein level in culture media by elisa assay and protein levels in mgc by western blot analysis. |
2013-03-27 |
2023-08-12 |
mouse |
| N Ally, X L Zou, B C Jiang, L Qin, L Zhai, P Xiao, H L Li. Inhibition of vascular endothelial growth factor A expression in mouse granulosa cells by lentivector-mediated RNAi. Genetics and molecular research : GMR. vol 11. issue 4. 2013-03-27. PMID:23212339. |
there was significant knockdown of the vegfa gene, receptor genes and apoptosis genes for all the shvegf constructs, compared with the shnc and mock controls. |
2013-03-27 |
2023-08-12 |
mouse |
| Gavasker A Sivaskandarajah, Marie Jeansson, Yoshiro Maezawa, Vera Eremina, Hans J Baelde, Susan E Quaggi. Vegfa protects the glomerular microvasculature in diabetes. Diabetes. vol 61. issue 11. 2013-01-14. PMID:23093658. |
after 7 weeks of diabetes, diabetic mice lacking vegfa in podocytes exhibited significantly greater proteinuria with profound glomerular scarring and increased apoptosis compared with control mice with diabetes or vegfa deletion without diabetes. |
2013-01-14 |
2023-08-12 |
mouse |
| Min Zhu, Zhengyu Zhou, Yan Chen, Ronda Schreiber, John T Ransom, John K Fraser, Marc H Hedrick, Kai Pinkernell, Hai-Chien Ku. Supplementation of fat grafts with adipose-derived regenerative cells improves long-term graft retention. Annals of plastic surgery. vol 64. issue 2. 2010-04-14. PMID:20098110. |
further cell tracking and gene expression studies suggest adrcs may promote angiogenesis and adipocyte differentiation and prevent apoptosis through the expression of various growth factors, including vegfa and igf-1. |
2010-04-14 |
2023-08-12 |
Not clear |
| Dalhia Abramovich, Griselda Irusta, Fernanda Parborell, Marta Teson. Intrabursal injection of vascular endothelial growth factor trap in eCG-treated prepubertal rats inhibits proliferation and increases apoptosis of follicular cells involving the PI3K/AKT signaling pathway. Fertility and sterility. vol 93. issue 5. 2010-04-02. PMID:19328472. |
to investigate the effects of local inhibition of vascular endothelial growth factor a (vegfa) on proliferation and apoptosis of follicular cells in rat ovaries. |
2010-04-02 |
2023-08-12 |
rat |
| Ahlame Saidi, Martin Hagedorn, Nathalie Allain, Chiara Verpelli, Carlo Sala, Lorenzo Bello, Andreas Bikfalvi, Sophie Javerza. Combined targeting of interleukin-6 and vascular endothelial growth factor potently inhibits glioma growth and invasiveness. International journal of cancer. vol 125. issue 5. 2009-08-25. PMID:19431143. |
interleukin-6 (il6) and vascular endothelial growth factor (vegfa) are abundantly produced by glioma cells and contribute to malignancy by promoting angiogenesis, cell proliferation and resistance to apoptosis. |
2009-08-25 |
2023-08-12 |
mouse |
| Dalhia Abramovich, Fernanda Parborell, Marta Teson. Effect of a vascular endothelial growth factor (VEGF) inhibitory treatment on the folliculogenesis and ovarian apoptosis in gonadotropin-treated prepubertal rats. Biology of reproduction. vol 75. issue 3. 2007-11-13. PMID:16775226. |
the effect of an intrabursal administration of a vegfa antagonist on follicular development, apoptosis, and levels of pro- and antiapoptotic proteins of bcl2 family members (bax, bcl2, and bcl2l1), as well as of tnfrsf6 (also known as fas) and fas ligand (faslg), was examined. |
2007-11-13 |
2023-08-12 |
rat |
| Dalhia Abramovich, Fernanda Parborell, Marta Teson. Effect of a vascular endothelial growth factor (VEGF) inhibitory treatment on the folliculogenesis and ovarian apoptosis in gonadotropin-treated prepubertal rats. Biology of reproduction. vol 75. issue 3. 2007-11-13. PMID:16775226. |
we concluded that the local inhibition of vegfa activity appears to produce an increase in ovarian apoptosis through an imbalance among the bcl2 family members, thus leading a larger number of follicles to atresia. |
2007-11-13 |
2023-08-12 |
rat |
| Magdalena Olbryt, Michał Jarzab, Joanna Jazowiecka-Rakus, Krzysztof Simek, Stanisław Szala, Aleksander Sochani. Gene expression profile of B 16(F10) murine melanoma cells exposed to hypoxic conditions in vitro. Gene expression. vol 13. issue 3. 2007-01-25. PMID:17193925. |
we observed significant differences in expression levels of genes regulating glycolysis (pfkp, hk2, aldo3, eno2), apoptosis (bnip3, bnip31, cdknla), transcription (bhlhb2, sap30, atf3, mxil), angiogenesis (vegfa, adm, anxa2, ctgf), adhesion (pkp2, itga4, mcam), migration (cnn2, tmsb4x), and other processes. |
2007-01-25 |
2023-08-12 |
Not clear |