| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hatice Akpınar, Mustafa Nazıroğlu, İshak Suat Övey, Bilal Çiğ, Orhan Akpına. The neuroprotective action of dexmedetomidine on apoptosis, calcium entry and oxidative stress in cerebral ischemia-induced rats: Contribution of TRPM2 and TRPV1 channels. Scientific reports. vol 6. 2018-05-18. PMID:27872485. |
dexmedetomidine (dex) may act as an antioxidant through regulation of trpm2 and trpv1 channel activations in the neurons by reducing cerebral ischemia-induced oxidative stress and apoptosis. |
2018-05-18 |
2023-08-13 |
rat |
| Jiayan Lei, Fengxi Zhu, Yi Zhang, Lixiao Duan, Han Lei, Wei Huan. Transient Receptor Potential Vanilloid Subtype 1 Inhibits Inflammation and Apoptosis via the Release of Calcitonin Gene-Related Peptide in the Heart after Myocardial Infarction. Cardiology. vol 134. issue 4. 2018-01-25. PMID:27144592. |
the objective of this study was to clarify whether calcitonin gene-related peptide (cgrp) release was associated with the protective role of trpv1 against postmyocardial inflammation and apoptosis. |
2018-01-25 |
2023-08-13 |
Not clear |
| Ümit Sinan Özdemir, Mustafa Nazıroğlu, Nilgün Şenol, Vahid Ghazizade. Hypericum perforatum Attenuates Spinal Cord Injury-Induced Oxidative Stress and Apoptosis in the Dorsal Root Ganglion of Rats: Involvement of TRPM2 and TRPV1 Channels. Molecular neurobiology. vol 53. issue 6. 2017-12-29. PMID:26099309. |
hypericum perforatum attenuates spinal cord injury-induced oxidative stress and apoptosis in the dorsal root ganglion of rats: involvement of trpm2 and trpv1 channels. |
2017-12-29 |
2023-08-13 |
human |
| Ümit Sinan Özdemir, Mustafa Nazıroğlu, Nilgün Şenol, Vahid Ghazizade. Hypericum perforatum Attenuates Spinal Cord Injury-Induced Oxidative Stress and Apoptosis in the Dorsal Root Ganglion of Rats: Involvement of TRPM2 and TRPV1 Channels. Molecular neurobiology. vol 53. issue 6. 2017-12-29. PMID:26099309. |
we aimed to investigate the protective property of hp on oxidative stress, apoptosis, and ca(2+) entry through transient receptor potential melastatin 2 (trpm2) and transient receptor potential vanilloid 1 (trpv1) channels in sci-induced drg neurons of rats. |
2017-12-29 |
2023-08-13 |
human |
| Ümit Sinan Özdemir, Mustafa Nazıroğlu, Nilgün Şenol, Vahid Ghazizade. Hypericum perforatum Attenuates Spinal Cord Injury-Induced Oxidative Stress and Apoptosis in the Dorsal Root Ganglion of Rats: Involvement of TRPM2 and TRPV1 Channels. Molecular neurobiology. vol 53. issue 6. 2017-12-29. PMID:26099309. |
in conclusion, we observed a protective role of hp on sci-induced oxidative stress, apoptosis, and ca(2+) entry through trpm2 and trpv1 in the drg neurons. |
2017-12-29 |
2023-08-13 |
human |
| Ümit Sinan Özdemir, Mustafa Nazıroğlu, Nilgün Şenol, Vahid Ghazizade. Hypericum perforatum Attenuates Spinal Cord Injury-Induced Oxidative Stress and Apoptosis in the Dorsal Root Ganglion of Rats: Involvement of TRPM2 and TRPV1 Channels. Molecular neurobiology. vol 53. issue 6. 2017-12-29. PMID:26099309. |
graphical abstract possible molecular pathways of involvement of hypericum perforatum (hp) on apoptosis, oxidative stress, and calcium accumulation through trpm2 and trpv1 channels in drg neurons of sci-induced rats. |
2017-12-29 |
2023-08-13 |
human |
| Francesca Punzo, Chiara Tortora, Daniela Di Pinto, Iolanda Manzo, Giulia Bellini, Fiorina Casale, Francesca Ross. Anti-proliferative, pro-apoptotic and anti-invasive effect of EC/EV system in human osteosarcoma. Oncotarget. vol 8. issue 33. 2017-09-25. PMID:28903355. |
we investigated the effects of jwh-133 (cb2 agonist) and rtx (trpv1 agonist) in six human osteosarcoma cell lines: mg-63, u-2os, mnng/hos, saos-2, khos/np, hs888lu, by apoptosis and migration-assay. |
2017-09-25 |
2023-08-13 |
human |
| b' P\\xc4\\xb1nar Aslan Ko\\xc5\\x9far, Mustafa Naz\\xc4\\xb1ro\\xc4\\x9flu, \\xc4\\xb0shak Suat \\xc3\\x96vey, Bilal \\xc3\\x87i\\xc4\\x9. Synergic Effects of Doxorubicin and Melatonin on Apoptosis and Mitochondrial Oxidative Stress in MCF-7 Breast Cancer Cells: Involvement of TRPV1 Channels. The Journal of membrane biology. vol 249. issue 1-2. 2017-07-28. PMID:26525975.' |
synergic effects of doxorubicin and melatonin on apoptosis and mitochondrial oxidative stress in mcf-7 breast cancer cells: involvement of trpv1 channels. |
2017-07-28 |
2023-08-13 |
human |
| b' P\\xc4\\xb1nar Aslan Ko\\xc5\\x9far, Mustafa Naz\\xc4\\xb1ro\\xc4\\x9flu, \\xc4\\xb0shak Suat \\xc3\\x96vey, Bilal \\xc3\\x87i\\xc4\\x9. Synergic Effects of Doxorubicin and Melatonin on Apoptosis and Mitochondrial Oxidative Stress in MCF-7 Breast Cancer Cells: Involvement of TRPV1 Channels. The Journal of membrane biology. vol 249. issue 1-2. 2017-07-28. PMID:26525975.' |
we aimed to investigate the effects of mel and dox on the oxidative toxicity of mcf-7 human breast cancer cells, in addition to the activity of the trpv1 channel and apoptosis. |
2017-07-28 |
2023-08-13 |
human |
| b' P\\xc4\\xb1nar Aslan Ko\\xc5\\x9far, Mustafa Naz\\xc4\\xb1ro\\xc4\\x9flu, \\xc4\\xb0shak Suat \\xc3\\x96vey, Bilal \\xc3\\x87i\\xc4\\x9. Synergic Effects of Doxorubicin and Melatonin on Apoptosis and Mitochondrial Oxidative Stress in MCF-7 Breast Cancer Cells: Involvement of TRPV1 Channels. The Journal of membrane biology. vol 249. issue 1-2. 2017-07-28. PMID:26525975.' |
taken together, the findings indicate that mel supported the effects of dox by activation of trpv1 and apoptosis, as well as by inducing mcf-7 cell death. |
2017-07-28 |
2023-08-13 |
human |
| Hasan Balaban, Mustafa Nazıroğlu, Kadir Demirci, İshak Suat Öve. The Protective Role of Selenium on Scopolamine-Induced Memory Impairment, Oxidative Stress, and Apoptosis in Aged Rats: The Involvement of TRPM2 and TRPV1 Channels. Molecular neurobiology. vol 54. issue 4. 2017-07-07. PMID:27021021. |
the protective role of selenium on scopolamine-induced memory impairment, oxidative stress, and apoptosis in aged rats: the involvement of trpm2 and trpv1 channels. |
2017-07-07 |
2023-08-13 |
rat |
| Esin Sakallı Çetin, Mustafa Nazıroğlu, Bilal Çiğ, İshak Suat Övey, Pınar Aslan Koşa. Selenium potentiates the anticancer effect of cisplatin against oxidative stress and calcium ion signaling-induced intracellular toxicity in MCF-7 breast cancer cells: involvement of the TRPV1 channel. Journal of receptor and signal transduction research. vol 37. issue 1. 2017-04-25. PMID:27055401. |
although previous studies have implicated the transient receptor potential vanilloid 1 (trpv1) cation channel, the synergistic inhibition effects of selenium (se) and cisplatin in cancer and the suppression of ongoing apoptosis have not yet been investigated in mcf-7 breast cancer cells. |
2017-04-25 |
2023-08-13 |
Not clear |
| Keisuke Nishino, Keisuke Tanamachi, Yuto Nakanishi, Shunta Ide, Shuji Kojima, Sei-Ichi Tanuma, Mitsutoshi Tsukimot. Radiosensitizing Effect of TRPV1 Channel Inhibitors in Cancer Cells. Biological & pharmaceutical bulletin. vol 39. issue 7. 2017-02-01. PMID:27150432. |
these results suggest that inhibition of dna repair by trpv1 channel inhibitors in irradiated a549 cells caused gradual loss of proliferative ability, rather than acute facilitation of apoptosis or necrosis. |
2017-02-01 |
2023-08-13 |
human |
| Long Zheng, Jiaqi Chen, Zhenkun Ma, Wei Liu, Fei Yang, Zhao Yang, Ke Wang, Xinyang Wang, Dalin He, Lei Li, Jin Zen. Capsaicin enhances anti-proliferation efficacy of pirarubicin via activating TRPV1 and inhibiting PCNA nuclear translocation in 5637 cells. Molecular medicine reports. vol 13. issue 1. 2016-10-05. PMID:26648574. |
previous studies have shown that transient receptor potential vanilloid 1 (trpv1) acts as a tumor suppressor through inducing apoptosis in bladder cancer cells. |
2016-10-05 |
2023-08-13 |
Not clear |
| Ji-Chen Ho, Chih-Hung Le. TRP channels in skin: from physiological implications to clinical significances. Biophysics (Nagoya-shi, Japan). vol 11. 2016-08-05. PMID:27493510. |
trpv1 and trpv3 in keratinocytes of the epidermis and hair apparatus inhibit proliferation, induce terminal differentiation, induce apoptosis, and promote inflammation. |
2016-08-05 |
2023-08-13 |
human |
| Luis Sánchez-Sánchez, Jesús J Alvarado-Sansininea, María L Escobar, Hugo López-Muñoz, José M V Hernández-Vázquez, Iván Monsalvo-Montiel, Patricia Demare, Ignacio Regla, Benny Weiss-Steide. Evaluation of the antitumour activity of Rinvanil and Phenylacetylrinvanil on the cervical cancer tumour cell lines HeLa, CaSKi and ViBo. European journal of pharmacology. vol 758. 2016-04-26. PMID:25864613. |
capsaicin is a potent inducer of apoptosis in tumourreceptor potential vanilloid 1 (trpv1). |
2016-04-26 |
2023-08-13 |
Not clear |
| Luis Sánchez-Sánchez, Jesús J Alvarado-Sansininea, María L Escobar, Hugo López-Muñoz, José M V Hernández-Vázquez, Iván Monsalvo-Montiel, Patricia Demare, Ignacio Regla, Benny Weiss-Steide. Evaluation of the antitumour activity of Rinvanil and Phenylacetylrinvanil on the cervical cancer tumour cell lines HeLa, CaSKi and ViBo. European journal of pharmacology. vol 758. 2016-04-26. PMID:25864613. |
finally, we discuss the possible loss of the relation between apoptosis and affinity to trpv1, and the need for other strategies to synthesise capsaicin analogues that can be useful in cancer treatments. |
2016-04-26 |
2023-08-13 |
Not clear |
| Jun Lu, You-Ting Ju, Chang Li, Fu-Zhou Hua, Guo-Hai Xu, Yan-Hui H. Effect of TRPV1 combined with lidocaine on cell state and apoptosis of U87-MG glioma cell lines. Asian Pacific journal of tropical medicine. vol 9. issue 3. 2016-03-14. PMID:26972404. |
effect of trpv1 combined with lidocaine on cell state and apoptosis of u87-mg glioma cell lines. |
2016-03-14 |
2023-08-13 |
Not clear |
| Jun Lu, You-Ting Ju, Chang Li, Fu-Zhou Hua, Guo-Hai Xu, Yan-Hui H. Effect of TRPV1 combined with lidocaine on cell state and apoptosis of U87-MG glioma cell lines. Asian Pacific journal of tropical medicine. vol 9. issue 3. 2016-03-14. PMID:26972404. |
to study the effects of transient receptor potential cation channel, subfamily v, member 1 (trpv1) combined with lidocaine on status and apoptosis of u87-mg glioma cell line, and explore whether local anesthetic produces neurotoxicity by trpv1. |
2016-03-14 |
2023-08-13 |
Not clear |
| Rebecca M Sappington, Tatiana Sidorova, Nicholas J Ward, Rohini Chakravarthy, Karen W Ho, David J Calkin. Activation of transient receptor potential vanilloid-1 (TRPV1) influences how retinal ganglion cell neurons respond to pressure-related stress. Channels (Austin, Tex.). vol 9. issue 2. 2016-02-08. PMID:25713995. |
in retinal explants, contrary to our animal studies, both trpv1 -/- and pharmacological antagonism of the channel prevented pressure-induced rgc apoptosis, as did chelation of extracellular ca(2+). |
2016-02-08 |
2023-08-13 |
mouse |