| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M A Costa, B M Fonseca, E Keating, N A Teixeira, G Correia-da-Silv. Transient receptor potential vanilloid 1 is expressed in human cytotrophoblasts: induction of cell apoptosis and impairment of syncytialization. The international journal of biochemistry & cell biology. vol 57. 2015-09-15. PMID:25450464. |
in conclusion, we showed that trpv1 is expressed in human cytotrophoblasts and syncytiotrophoblasts and also reported the involvement of this receptor in cytotrophoblast apoptosis and differentiation. |
2015-09-15 |
2023-08-13 |
human |
| Anna Pilutin, Kamila Misiakiewicz-Has, Agnieszka Kolasa, Irena Baranowska-Bosiacka, Mariola Marchlewicz, Barbara Wiszniewsk. The immunoexpression of androgen receptor, estrogen receptors alpha and beta, vanilloid type 1 receptor and cytochrome p450 aromatase in rats testis chronically treated with letrozole, an aromatase inhibitor. Folia histochemica et cytobiologica. vol 52. issue 3. 2015-07-23. PMID:25308736. |
therefore the aim of the study was to investigate the expression of androgen and estrogen receptors (ar, ers), vanilloid receptor (trpv1), cytochrome p450 aromatase (p450arom), as well as apoptosis of cells in testis of adult rats chronically treated with letrozole (lt), a non-steroidal aromatase inhibitor, for 6 months. |
2015-07-23 |
2023-08-13 |
rat |
| Zewei Sun, Jie Han, Wenting Zhao, Yuanyuan Zhang, Shuai Wang, Lifang Ye, Tingting Liu, Liangrong Zhen. TRPV1 activation exacerbates hypoxia/reoxygenation-induced apoptosis in H9C2 cells via calcium overload and mitochondrial dysfunction. International journal of molecular sciences. vol 15. issue 10. 2015-06-25. PMID:25314299. |
trpv1 activation exacerbates hypoxia/reoxygenation-induced apoptosis in h9c2 cells via calcium overload and mitochondrial dysfunction. |
2015-06-25 |
2023-08-13 |
mouse |
| Zewei Sun, Jie Han, Wenting Zhao, Yuanyuan Zhang, Shuai Wang, Lifang Ye, Tingting Liu, Liangrong Zhen. TRPV1 activation exacerbates hypoxia/reoxygenation-induced apoptosis in H9C2 cells via calcium overload and mitochondrial dysfunction. International journal of molecular sciences. vol 15. issue 10. 2015-06-25. PMID:25314299. |
recent studies show that trpv1 channels are also expressed on cardiomyocytes and can exacerbate air pollutant-induced apoptosis. |
2015-06-25 |
2023-08-13 |
mouse |
| Zewei Sun, Jie Han, Wenting Zhao, Yuanyuan Zhang, Shuai Wang, Lifang Ye, Tingting Liu, Liangrong Zhen. TRPV1 activation exacerbates hypoxia/reoxygenation-induced apoptosis in H9C2 cells via calcium overload and mitochondrial dysfunction. International journal of molecular sciences. vol 15. issue 10. 2015-06-25. PMID:25314299. |
in the present study, we investigated the role of trpv1 in h/r induced apoptosis of h9c2 cardiomyocytes. |
2015-06-25 |
2023-08-13 |
mouse |
| Zewei Sun, Jie Han, Wenting Zhao, Yuanyuan Zhang, Shuai Wang, Lifang Ye, Tingting Liu, Liangrong Zhen. TRPV1 activation exacerbates hypoxia/reoxygenation-induced apoptosis in H9C2 cells via calcium overload and mitochondrial dysfunction. International journal of molecular sciences. vol 15. issue 10. 2015-06-25. PMID:25314299. |
although neuropeptide release caused by trpv1 activation on sensory neurons elicits a cardioprotective effect, we found that capsaicin (cap; a trpv1 agonist) treatment of h9c2 cells paradoxically enhanced the level of apoptosis by increasing intracellular calcium and mitochondrial superoxide levels, attenuating mitochondrial membrane potential, and inhibiting mitochondrial biogenesis (measured by the expression of atp synthase β). |
2015-06-25 |
2023-08-13 |
mouse |
| Zewei Sun, Jie Han, Wenting Zhao, Yuanyuan Zhang, Shuai Wang, Lifang Ye, Tingting Liu, Liangrong Zhen. TRPV1 activation exacerbates hypoxia/reoxygenation-induced apoptosis in H9C2 cells via calcium overload and mitochondrial dysfunction. International journal of molecular sciences. vol 15. issue 10. 2015-06-25. PMID:25314299. |
in summary, direct activation of trpv1 in myocytes exacerbates h/r-induced apoptosis, likely through calcium overload and associated mitochondrial dysfunction. |
2015-06-25 |
2023-08-13 |
mouse |
| Mustafa Nazıroğlu, Nilgün Senol, Vahid Ghazizadeh, Vehbi Yürüke. Neuroprotection induced by N-acetylcysteine and selenium against traumatic brain injury-induced apoptosis and calcium entry in hippocampus of rat. Cellular and molecular neurobiology. vol 34. issue 6. 2015-03-31. PMID:24842665. |
therefore, we tested the effects of se and nac administration on apoptosis, oxidative stress, and ca(2+) influx through trpv1 channel activations in the hippocampus of tbi-induced rats. |
2015-03-31 |
2023-08-13 |
rat |
| Mustafa Nazıroğlu, Nilgün Senol, Vahid Ghazizadeh, Vehbi Yürüke. Neuroprotection induced by N-acetylcysteine and selenium against traumatic brain injury-induced apoptosis and calcium entry in hippocampus of rat. Cellular and molecular neurobiology. vol 34. issue 6. 2015-03-31. PMID:24842665. |
in conclusion, we observed that nac and se have protective effects on oxidative stress, apoptosis, and ca(2+) entry via trpv1 channel activation in the hippocampus of this tbi model, but the effect of nac appears to be much greater than that of se. |
2015-03-31 |
2023-08-13 |
rat |
| Jamie K Lau, Kathleen C Brown, Aaron M Dom, Theodore R Witte, Brent A Thornhill, Clayton M Crabtree, Haley E Perry, J Michael Brown, John G Ball, Rebecca G Creel, C Luke Damron, William D Rollyson, Cathryn D Stevenson, W Elaine Hardman, Monica A Valentovic, A Betts Carpenter, Piyali Dasgupt. Capsaicin induces apoptosis in human small cell lung cancer via the TRPV6 receptor and the calpain pathway. Apoptosis : an international journal on programmed cell death. vol 19. issue 8. 2015-01-30. PMID:24878626. |
we observed that capsaicin-induced apoptosis in human sclc cells was mediated via the trpv receptor family; however it was independent of trpv1. |
2015-01-30 |
2023-08-13 |
human |
| Zhaohui Pei, Zhiqiang Zhuang, Hanfei Sang, Zhenbiao Wu, Rongsen Meng, Emily Y He, Glenda I Scott, Jackie R Maris, Ruiman Li, Jun Re. α,β-Unsaturated aldehyde crotonaldehyde triggers cardiomyocyte contractile dysfunction: role of TRPV1 and mitochondrial function. Pharmacological research. vol 82. 2014-12-29. PMID:24705155. |
apoptosis and trpv1 were evaluated using western blot analysis. |
2014-12-29 |
2023-08-13 |
Not clear |
| Zhaohui Pei, Zhiqiang Zhuang, Hanfei Sang, Zhenbiao Wu, Rongsen Meng, Emily Y He, Glenda I Scott, Jackie R Maris, Ruiman Li, Jun Re. α,β-Unsaturated aldehyde crotonaldehyde triggers cardiomyocyte contractile dysfunction: role of TRPV1 and mitochondrial function. Pharmacological research. vol 82. 2014-12-29. PMID:24705155. |
crotonaldehyde exposure increased trpv1 and nadph oxidase levels, promoted apoptosis, mitochondrial injury (decreased aconitase activity, pgc-1α and ucp-2) as well as production of ros and 8-ohdg. |
2014-12-29 |
2023-08-13 |
Not clear |
| N Takahashi, Y Matsuda, H Yamada, K Tabeta, T Nakajima, S Murakami, K Yamazak. Epithelial TRPV1 signaling accelerates gingival epithelial cell proliferation. Journal of dental research. vol 93. issue 11. 2014-12-18. PMID:25266715. |
no effects were observed on gec apoptosis by epithelial trpv1 signaling. |
2014-12-18 |
2023-08-13 |
mouse |
| Cara B Gonzales, Nameer B Kirma, Jorge J De La Chapa, Richard Chen, Michael A Henry, Songjiang Luo, Kenneth M Hargreave. Vanilloids induce oral cancer apoptosis independent of TRPV1. Oral oncology. vol 50. issue 5. 2014-12-10. PMID:24434067. |
vanilloids induce oral cancer apoptosis independent of trpv1. |
2014-12-10 |
2023-08-12 |
Not clear |
| Li-Min Zhao, Hong-Yan Kuang, Luo-Xian Zhang, Ji-Zhen Wu, Xian-Liang Chen, Xiao-Yu Zhang, Li-Jun M. Effect of TRPV1 channel on proliferation and apoptosis of airway smooth muscle cells of rats. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 34. issue 4. 2014-11-21. PMID:25135718. |
effect of trpv1 channel on proliferation and apoptosis of airway smooth muscle cells of rats. |
2014-11-21 |
2023-08-13 |
rat |
| Li-Min Zhao, Hong-Yan Kuang, Luo-Xian Zhang, Ji-Zhen Wu, Xian-Liang Chen, Xiao-Yu Zhang, Li-Jun M. Effect of TRPV1 channel on proliferation and apoptosis of airway smooth muscle cells of rats. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 34. issue 4. 2014-11-21. PMID:25135718. |
this study investigated the expression and activity of trpv1 channel, and further clarified the effect of trpv1 channel on the asmcs proliferation and apoptosis in order to provide the scientific basis to treat asthmatic airway remodeling in clinical practice. |
2014-11-21 |
2023-08-13 |
rat |
| M Skrzypski, M Sassek, S Abdelmessih, S Mergler, C Grötzinger, D Metzke, T Wojciechowicz, K W Nowak, M Z Strowsk. Capsaicin induces cytotoxicity in pancreatic neuroendocrine tumor cells via mitochondrial action. Cellular signalling. vol 26. issue 1. 2014-06-25. PMID:24075930. |
in the present study, we characterize the role of the trpv1 agonist - cap - in controlling proliferation and apoptosis of pancreatic bon and qgp-1 net cells. |
2014-06-25 |
2023-08-12 |
Not clear |
| Limin Zhao, Xiaoyu Zhang, Hongyan Kuang, Jizhen Wu, Yali Guo, Lijun M. Effect of TRPV1 channel on the proliferation and apoptosis in asthmatic rat airway smooth muscle cells. Experimental lung research. vol 39. issue 7. 2014-04-21. PMID:23919305. |
effect of trpv1 channel on the proliferation and apoptosis in asthmatic rat airway smooth muscle cells. |
2014-04-21 |
2023-08-12 |
rat |
| Limin Zhao, Xiaoyu Zhang, Hongyan Kuang, Jizhen Wu, Yali Guo, Lijun M. Effect of TRPV1 channel on the proliferation and apoptosis in asthmatic rat airway smooth muscle cells. Experimental lung research. vol 39. issue 7. 2014-04-21. PMID:23919305. |
this study explores the expression of trpv1 channel and its effect on the proliferation and apoptosis in rat asmc, in order to find a new target to treat airway remodeling in asthma. |
2014-04-21 |
2023-08-12 |
rat |
| Leiting Pan, Kun Song, Fen Hu, Wenwu Sun, Imshik Le. Nitric oxide induces apoptosis associated with TRPV1 channel-mediated Ca(2+) entry via S-nitrosylation in osteoblasts. European journal of pharmacology. vol 715. issue 1-3. 2014-04-14. PMID:23707350. |
nitric oxide induces apoptosis associated with trpv1 channel-mediated ca(2+) entry via s-nitrosylation in osteoblasts. |
2014-04-14 |
2023-08-12 |
Not clear |