| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Leiting Pan, Kun Song, Fen Hu, Wenwu Sun, Imshik Le. Nitric oxide induces apoptosis associated with TRPV1 channel-mediated Ca(2+) entry via S-nitrosylation in osteoblasts. European journal of pharmacology. vol 715. issue 1-3. 2014-04-14. PMID:23707350. |
additionally, 1mm snp induced osteoblast apoptosis, which was largely inhibited by the blockers of trpv1, capsazepine and ruthenium red. |
2014-04-14 |
2023-08-12 |
Not clear |
| Leiting Pan, Kun Song, Fen Hu, Wenwu Sun, Imshik Le. Nitric oxide induces apoptosis associated with TRPV1 channel-mediated Ca(2+) entry via S-nitrosylation in osteoblasts. European journal of pharmacology. vol 715. issue 1-3. 2014-04-14. PMID:23707350. |
taken together, our data clearly demonstrated that the no donor snp resulted in apoptosis associated with trpv1 channel-mediated ca(2+) entry via s-nitrosylation in osteoblasts. |
2014-04-14 |
2023-08-12 |
Not clear |
| Rakhshinda Rehman, Younus Ahmad Bhat, Lipsa Panda, Ulaganathan Mabaliraja. TRPV1 inhibition attenuates IL-13 mediated asthma features in mice by reducing airway epithelial injury. International immunopharmacology. vol 15. issue 3. 2013-09-20. PMID:23453702. |
further, trpv1 sirna treatment reduced not only the cytosolic calpain and mitochondrial calpain 10 activities in the lung but also bronchial epithelial apoptosis indicating that trpv1 sirna might have corrected the intracellular and intramitochondrial calcium overload and its consequent apoptosis. |
2013-09-20 |
2023-08-12 |
mouse |
| Mauro Leonelli, Daniel O Martins, Luiz R G Britt. Retinal cell death induced by TRPV1 activation involves NMDA signaling and upregulation of nitric oxide synthases. Cellular and molecular neurobiology. vol 33. issue 3. 2013-09-04. PMID:23324998. |
our previous results indicate that trpv1 activation in the adult retina can lead to constitutive and inducible nitric oxide synthase-dependent protein nitration and apoptosis. |
2013-09-04 |
2023-08-12 |
Not clear |
| M Mecha, A S Torrao, L Mestre, F J Carrillo-Salinas, R Mechoulam, C Guaz. Cannabidiol protects oligodendrocyte progenitor cells from inflammation-induced apoptosis by attenuating endoplasmic reticulum stress. Cell death & disease. vol 3. 2013-07-23. PMID:22739983. |
cbd also protects opcs from apoptosis induced by lps/ifnγ through the decrease of caspase 3 induction via mechanisms that do not involve cb1, cb2, trpv1 or pparγ receptors. |
2013-07-23 |
2023-08-12 |
Not clear |
| Bokyung Sung, Sahdeo Prasad, Jayaraj Ravindran, Vivek R Yadav, Bharat B Aggarwa. Capsazepine, a TRPV1 antagonist, sensitizes colorectal cancer cells to apoptosis by TRAIL through ROS-JNK-CHOP-mediated upregulation of death receptors. Free radical biology & medicine. vol 53. issue 10. 2013-06-10. PMID:22922338. |
capsazepine, a trpv1 antagonist, sensitizes colorectal cancer cells to apoptosis by trail through ros-jnk-chop-mediated upregulation of death receptors. |
2013-06-10 |
2023-08-12 |
human |
| Bokyung Sung, Sahdeo Prasad, Jayaraj Ravindran, Vivek R Yadav, Bharat B Aggarwa. Capsazepine, a TRPV1 antagonist, sensitizes colorectal cancer cells to apoptosis by TRAIL through ROS-JNK-CHOP-mediated upregulation of death receptors. Free radical biology & medicine. vol 53. issue 10. 2013-06-10. PMID:22922338. |
in this study, we evaluated capsazepine, a trpv1 antagonist, for its ability to sensitize human colon cancer cells to trail-induced apoptosis. |
2013-06-10 |
2023-08-12 |
human |
| Mauro Leonelli, Daniel O Martins, Luiz R G Britt. TRPV1 receptors modulate retinal development. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 29. issue 4. 2011-09-13. PMID:21414401. |
we investigated the possible participation of trpv1 channels in retinal apoptosis and overall development. |
2011-09-13 |
2023-08-12 |
rat |
| Mauro Leonelli, Daniel O Martins, Luiz R G Britt. TRPV1 receptors modulate retinal development. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 29. issue 4. 2011-09-13. PMID:21414401. |
our results indicate that trpv1 channels play a role in the control of the early apoptosis that occur during retinal development, which might be dependent on mapk signaling. |
2011-09-13 |
2023-08-12 |
rat |
| Debashree Mukherjea, Sarvesh Jajoo, Tejbeer Kaur, Kelly E Sheehan, Vickram Ramkumar, Leonard P Ryba. Transtympanic administration of short interfering (si)RNA for the NOX3 isoform of NADPH oxidase protects against cisplatin-induced hearing loss in the rat. Antioxidants & redox signaling. vol 13. issue 5. 2011-04-22. PMID:20214492. |
these data suggest that nox3 regulates stress-related genes in the cochlea, such as trpv1 and kim-1, and initiates apoptosis in the cochlea. |
2011-04-22 |
2023-08-12 |
rat |
| Amiya K Ghosh, Sreyashi Bas. Fas-associated factor 1 is a negative regulator in capsaicin induced cancer cell apoptosis. Cancer letters. vol 287. issue 2. 2010-03-02. PMID:19570606. |
recent reports have demonstrated that tumor cells express trpv1 and that capsaicin (cp), a ligand for trpv1, induces apoptosis in cancer cells. |
2010-03-02 |
2023-08-12 |
Not clear |
| Amiya K Ghosh, Sreyashi Bas. Fas-associated factor 1 is a negative regulator in capsaicin induced cancer cell apoptosis. Cancer letters. vol 287. issue 2. 2010-03-02. PMID:19570606. |
here, we investigated the role of trpv1 in tumor apoptosis using trpv1-expressing cancer cell lines. |
2010-03-02 |
2023-08-12 |
Not clear |
| Amiya K Ghosh, Sreyashi Bas. Fas-associated factor 1 is a negative regulator in capsaicin induced cancer cell apoptosis. Cancer letters. vol 287. issue 2. 2010-03-02. PMID:19570606. |
we demonstrate that iodo-resiniferatoxin (i-rtx), an antagonist of trpv1 does not inhibit cp mediated apoptosis nor is it cytotoxic by itself, but acts as a partial agonist and shows synergistic effect with cp. |
2010-03-02 |
2023-08-12 |
Not clear |
| Amiya K Ghosh, Sreyashi Bas. Fas-associated factor 1 is a negative regulator in capsaicin induced cancer cell apoptosis. Cancer letters. vol 287. issue 2. 2010-03-02. PMID:19570606. |
in summary, our data shows for the first time that the underlying mechanisms of cp-induced cancer cell apoptosis involves faf1, a trpv1 associated protein and serves as an important foundation for further understanding of anticancer activity of cp. |
2010-03-02 |
2023-08-12 |
Not clear |
| Consuelo Amantini, Patrizia Ballarini, Sara Caprodossi, Massimo Nabissi, Maria Beatrice Morelli, Roberta Lucciarini, Marco Andrea Cardarelli, Gabriele Mammana, Giorgio Santon. Triggering of transient receptor potential vanilloid type 1 (TRPV1) by capsaicin induces Fas/CD95-mediated apoptosis of urothelial cancer cells in an ATM-dependent manner. Carcinogenesis. vol 30. issue 8. 2009-09-01. PMID:19502594. |
triggering of transient receptor potential vanilloid type 1 (trpv1) by capsaicin induces fas/cd95-mediated apoptosis of urothelial cancer cells in an atm-dependent manner. |
2009-09-01 |
2023-08-12 |
human |
| Consuelo Amantini, Patrizia Ballarini, Sara Caprodossi, Massimo Nabissi, Maria Beatrice Morelli, Roberta Lucciarini, Marco Andrea Cardarelli, Gabriele Mammana, Giorgio Santon. Triggering of transient receptor potential vanilloid type 1 (TRPV1) by capsaicin induces Fas/CD95-mediated apoptosis of urothelial cancer cells in an ATM-dependent manner. Carcinogenesis. vol 30. issue 8. 2009-09-01. PMID:19502594. |
herein, we provide evidence on the expression of transient receptor potential vanilloid type 1 (trpv1) on human urothelial cancer (uc) cells and its involvement in the apoptosis induced by the selective agonist capsaicin (cps). |
2009-09-01 |
2023-08-12 |
human |
| Consuelo Amantini, Patrizia Ballarini, Sara Caprodossi, Massimo Nabissi, Maria Beatrice Morelli, Roberta Lucciarini, Marco Andrea Cardarelli, Gabriele Mammana, Giorgio Santon. Triggering of transient receptor potential vanilloid type 1 (TRPV1) by capsaicin induces Fas/CD95-mediated apoptosis of urothelial cancer cells in an ATM-dependent manner. Carcinogenesis. vol 30. issue 8. 2009-09-01. PMID:19502594. |
notably, atm activation was also found to control upregulation of fas/cd95 expression and its co-clustering with trpv1 as well as rt4 cell growth and apoptosis. |
2009-09-01 |
2023-08-12 |
human |
| b' Bal\\xc3\\xa1zs I T\\xc3\\xb3th, Tam\\xc3\\xa1s G\\xc3\\xa9czy, Zolt\\xc3\\xa1n Griger, Anik\\xc3\\xb3 D\\xc3\\xb3zsa, Holger Seltmann, L\\xc3\\xa1szl\\xc3\\xb3 Kov\\xc3\\xa1cs, L\\xc3\\xa1szl\\xc3\\xb3 Nagy, Christos C Zouboulis, Ralf Paus, Tam\\xc3\\xa1s B\\xc3\\xadr\\xc3\\xb. Transient receptor potential vanilloid-1 signaling as a regulator of human sebocyte biology. The Journal of investigative dermatology. vol 129. issue 2. 2009-02-27. PMID:18769453.' |
in human pilosebaceous units, we had shown that trpv1 stimulation inhibits hair shaft elongation and matrix keratinocyte proliferation, and induces premature hair follicle regression and keratinocyte apoptosis. |
2009-02-27 |
2023-08-12 |
human |
| Rebecca M Sappington, Tatiana Sidorova, Daniel J Long, David J Calkin. TRPV1: contribution to retinal ganglion cell apoptosis and increased intracellular Ca2+ with exposure to hydrostatic pressure. Investigative ophthalmology & visual science. vol 50. issue 2. 2009-02-06. PMID:18952924. |
trpv1: contribution to retinal ganglion cell apoptosis and increased intracellular ca2+ with exposure to hydrostatic pressure. |
2009-02-06 |
2023-08-12 |
Not clear |
| Debashree Mukherjea, Sarvesh Jajoo, Craig Whitworth, Jennifer R Bunch, Jeremy G Turner, Leonard P Rybak, Vickram Ramkuma. Short interfering RNA against transient receptor potential vanilloid 1 attenuates cisplatin-induced hearing loss in the rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 49. 2009-01-12. PMID:19052196. |
in organ of corti hair cell cultures (ub/oc-1 cells), cisplatin activates and induces trpv1 and nox3, leading to apoptosis of these cells. |
2009-01-12 |
2023-08-12 |
rat |