| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mustafa Güzel, Orhan Akpına. Hydroxychloroquine Attenuates Acute Inflammation (LPS)-Induced Apoptosis via Inhibiting TRPV1 Channel/ROS Signaling Pathways in Human Monocytes. Biology. vol 10. issue 10. 2021-10-26. PMID:34681066. |
hydroxychloroquine attenuates acute inflammation (lps)-induced apoptosis via inhibiting trpv1 channel/ros signaling pathways in human monocytes. |
2021-10-26 |
2023-08-13 |
human |
| Ranjana Bhandari, Reetrakshi Gupta, Anushka Vashishth, Anurag Kuha. Transient Receptor Potential Vanilloid 1 (TRPV1) as a plausible novel therapeutic target for treating neurological complications in ZikaVirus. Medical hypotheses. vol 156. 2021-10-18. PMID:34592564. |
opening of trpv1 channel also leads to calcium influx and oxidative stress that ultimately results in cellular apoptosis (like schwann cell in gbs and developing fetal nerve cells in microcephaly), ultimately leading to these complications. |
2021-10-18 |
2023-08-13 |
Not clear |
| Tingting Huang, Yao Lin, Qiongyi Pang, Weimin Shen, Xiang Chen, Fengxia T. The Synergistic Effect of TRPV1 on Oxidative Stress-Induced Autophagy and Apoptosis in Microglia. Analytical cellular pathology (Amsterdam). vol 2021. 2021-08-03. PMID:34336554. |
the synergistic effect of trpv1 on oxidative stress-induced autophagy and apoptosis in microglia. |
2021-08-03 |
2023-08-13 |
Not clear |
| Tingting Huang, Yao Lin, Qiongyi Pang, Weimin Shen, Xiang Chen, Fengxia T. The Synergistic Effect of TRPV1 on Oxidative Stress-Induced Autophagy and Apoptosis in Microglia. Analytical cellular pathology (Amsterdam). vol 2021. 2021-08-03. PMID:34336554. |
transient receptor potential vanilloid 1 (trpv1) has been shown to regulate oxidative stress and apoptosis in microglia; however, the detailed mechanisms remain unclear. |
2021-08-03 |
2023-08-13 |
Not clear |
| Tingting Huang, Yao Lin, Qiongyi Pang, Weimin Shen, Xiang Chen, Fengxia T. The Synergistic Effect of TRPV1 on Oxidative Stress-Induced Autophagy and Apoptosis in Microglia. Analytical cellular pathology (Amsterdam). vol 2021. 2021-08-03. PMID:34336554. |
we aimed to explore whether autophagy-regulated oxidative stress and apoptosis are associated with trpv1. |
2021-08-03 |
2023-08-13 |
Not clear |
| Tingting Huang, Yao Lin, Qiongyi Pang, Weimin Shen, Xiang Chen, Fengxia T. The Synergistic Effect of TRPV1 on Oxidative Stress-Induced Autophagy and Apoptosis in Microglia. Analytical cellular pathology (Amsterdam). vol 2021. 2021-08-03. PMID:34336554. |
the results indicated that oxidative stress-induced injury and apoptosis may be impeded by the increasing autophagy, and trpv1 inhibition could suppress the ogd/r-induced autophagy of microglia. |
2021-08-03 |
2023-08-13 |
Not clear |
| Tingting Huang, Yao Lin, Qiongyi Pang, Weimin Shen, Xiang Chen, Fengxia T. The Synergistic Effect of TRPV1 on Oxidative Stress-Induced Autophagy and Apoptosis in Microglia. Analytical cellular pathology (Amsterdam). vol 2021. 2021-08-03. PMID:34336554. |
however, the effect of trpv1's inhibitor on oxidative stress and apoptosis was not obvious when the autophagy was blocked. |
2021-08-03 |
2023-08-13 |
Not clear |
| Zeki Serdar Ataizi, Kemal Ertila. Pregabalin reduces oxaliplatin-induced oxidative neurotoxicity through modulation of TRPV1 channels in DBTRG neuronal cell line. Anti-cancer drugs. vol 31. issue 7. 2021-05-06. PMID:32459682. |
in the laser confocal microscope and plate reader analyses, apoptosis, mitochondrial membrane depolarization (jc-1), cell death (propidium iodide/hoechst rate), and ros-level production increased by activating trpv1 in the cells using the oxal treatment, although the cell viability values decreased. |
2021-05-06 |
2023-08-13 |
human |
| Zeki Serdar Ataizi, Kemal Ertila. Pregabalin reduces oxaliplatin-induced oxidative neurotoxicity through modulation of TRPV1 channels in DBTRG neuronal cell line. Anti-cancer drugs. vol 31. issue 7. 2021-05-06. PMID:32459682. |
in conclusion, the apoptosis and oxidant actions of oxal were increased by activation of the trpv1 channel, but this effect was diminished by the pregab treatment. |
2021-05-06 |
2023-08-13 |
human |
| Kevin Zhai, Alena Liskova, Peter Kubatka, Dietrich Büsselber. Calcium Entry through TRPV1: A Potential Target for the Regulation of Proliferation and Apoptosis in Cancerous and Healthy Cells. International journal of molecular sciences. vol 21. issue 11. 2021-03-25. PMID:32545311. |
calcium entry through trpv1: a potential target for the regulation of proliferation and apoptosis in cancerous and healthy cells. |
2021-03-25 |
2023-08-13 |
Not clear |
| Lukasz Szoka, Jerzy Palk. Capsaicin up-regulates pro-apoptotic activity of thiazolidinediones in glioblastoma cell line. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 132. 2021-02-19. PMID:33038582. |
we found that capsaicin stimulated intrinsic and extrinsic pathway of apoptosis in human glioblastoma ln-18 cell line and this phenomenon was not dependent on trpv1. |
2021-02-19 |
2023-08-13 |
human |
| Juan Song, Jian-Bin Pan, Wei Zhao, Hong-Yuan Chen, Jing-Juan X. Gold nanorod-assisted near-infrared light-mediated regulation of membrane ion channels activates apoptotic pathways. Chemical communications (Cambridge, England). vol 56. issue 45. 2021-01-13. PMID:32364208. |
we report a gnr-assisted nir-activated tool that could open trpv1 ion channels and regulate apoptotic protein expression, thereby inducing cell apoptosis, which might be an effective approach for cancer therapy. |
2021-01-13 |
2023-08-13 |
Not clear |
| Lea V Weber, Klaudia Al-Refae, Gerhard Wölk, Gabriele Bonatz, Janine Altmüller, Christian Becker, Günter Gisselmann, Hanns Hat. Expression and functionality of TRPV1 in breast cancer cells. Breast cancer (Dove Medical Press). vol 8. 2020-10-01. PMID:28008282. |
activation of trpv1 by capsaicin caused significant inhibition of cancer cell growth and induced apoptosis and necrosis. |
2020-10-01 |
2023-08-13 |
human |
| Yi-Yue Wang, Kyung-Tae Lee, Myong Cheol Lim, Jung-Hye Cho. TRPV1 Antagonist DWP05195 Induces ER Stress-Dependent Apoptosis through the ROS-p38-CHOP Pathway in Human Ovarian Cancer Cells. Cancers. vol 12. issue 6. 2020-09-28. PMID:32604833. |
trpv1 antagonist dwp05195 induces er stress-dependent apoptosis through the ros-p38-chop pathway in human ovarian cancer cells. |
2020-09-28 |
2023-08-13 |
human |
| Yan Chen, Junzhi Li, Lei Jin, Kai Lei, Haiwang Liu, Yong Yan. Fibulin-5 contributes to colorectal cancer cell apoptosis via the ROS/MAPK and Akt signal pathways by downregulating transient receptor potential cation channel subfamily V member 1. Journal of cellular biochemistry. vol 120. issue 10. 2020-09-09. PMID:31148262. |
furthermore, our study verified that fibulin-5 promoted cell apoptosis and reactive oxygen species (ros) production by inhibiting transient receptor potential cation channel subfamily v member 1 (trpv1) in crc cells. |
2020-09-09 |
2023-08-13 |
Not clear |
| Yan Chen, Junzhi Li, Lei Jin, Kai Lei, Haiwang Liu, Yong Yan. Fibulin-5 contributes to colorectal cancer cell apoptosis via the ROS/MAPK and Akt signal pathways by downregulating transient receptor potential cation channel subfamily V member 1. Journal of cellular biochemistry. vol 120. issue 10. 2020-09-09. PMID:31148262. |
moreover, nac (the scavenger of ros), sb203580 (the inhibitor of p38), pd98059 (the inhibitor of erk), and sc79 (the activator of akt) were used to uncover that fibulin-5 induced apoptosis through the ros/mitogen-activated protein kinase and akt signal pathways by downregulating trpv1. |
2020-09-09 |
2023-08-13 |
Not clear |
| Zhengqi Bao, Xiusong Dai, Peter Wang, Yisheng Tao, Damin Cha. Capsaicin induces cytotoxicity in human osteosarcoma MG63 cells through TRPV1-dependent and -independent pathways. Cell cycle (Georgetown, Tex.). vol 18. issue 12. 2020-07-03. PMID:31095448. |
we found that capsaicin-induced apoptosis and the activation of transient receptor potential receptor vanilloid 1 (trpv1) in a dose- and time-dependent manner in human osteosarcoma mg63 cells |
2020-07-03 |
2023-08-13 |
human |
| Nengyi Hou, Xuelai He, Yuhui Yang, Junwen Fu, Wei Zhang, Zhiyi Guo, Yang Hu, Liqin Liang, Wei Xie, Haibo Xiong, Kang Wang, Minghui Pan. TRPV1 Induced Apoptosis of Colorectal Cancer Cells by Activating Calcineurin-NFAT2-p53 Signaling Pathway. BioMed research international. vol 2019. 2019-12-06. PMID:31183372. |
trpv1 induced apoptosis of colorectal cancer cells by activating calcineurin-nfat2-p53 signaling pathway. |
2019-12-06 |
2023-08-13 |
Not clear |
| Consuelo Amantini, Valerio Farfariello, Claudio Cardinali, Maria Beatrice Morelli, Oliviero Marinelli, Massimo Nabissi, Matteo Santoni, Laura Bonfili, Valentina Cecarini, Anna Maria Eleuteri, Giorgio Santon. The TRPV1 ion channel regulates thymocyte differentiation by modulating autophagy and proteasome activity. Oncotarget. vol 8. issue 53. 2019-11-20. PMID:29207602. |
in addition, positive selection of thymocytes triggered by anti-tcrβ/cd2 ab-mediated costimulation induces apoptosis in thymocytes from trpv1 ko as compared with wt mice. |
2019-11-20 |
2023-08-13 |
mouse |
| Francesca Punzo, Iolanda Manzo, Chiara Tortora, Elvira Pota, Velia D' Angelo, Giulia Bellini, Alessandra Di Paola, Federica Verace, Fiorina Casale, Francesca Ross. Effects of CB2 and TRPV1 receptors' stimulation in pediatric acute T-lymphoblastic leukemia. Oncotarget. vol 9. issue 30. 2019-11-20. PMID:29765535. |
our results show that both cb2 stimulation and trpv1 activation, can increase the apoptosis |
2019-11-20 |
2023-08-13 |
Not clear |