| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tamara Saksida, Stanislava Stosic-Grujicic, Gordana Timotijevic, Stellan Sandler, Ivana Stojanovi. Macrophage migration inhibitory factor deficiency protects pancreatic islets from palmitic acid-induced apoptosis. Immunology and cell biology. vol 90. issue 7. 2013-01-04. PMID:22064706. |
further, mif gene deletion, mrna silencing or protein inhibition rescued β-cells from pa-induced apoptosis as measured by mtt assay and histone-dna enzyme linked immuno sorbent assay. |
2013-01-04 |
2023-08-12 |
mouse |
| Cinzia Lucia Ursini, Delia Cavallo, Anna Maria Fresegna, Aureliano Ciervo, Raffaele Maiello, Giuliana Buresti, Stefano Casciardi, Francesca Tombolini, Stefano Bellucci, Sergio Iavicol. Comparative cyto-genotoxicity assessment of functionalized and pristine multiwalled carbon nanotubes on human lung epithelial cells. Toxicology in vitro : an international journal published in association with BIBRA. vol 26. issue 6. 2013-01-04. PMID:22640919. |
cytotoxicity was evaluated by mtt and ldh tests and apoptosis induction, direct/oxidative dna damage by fpg-modified comet assay. |
2013-01-04 |
2023-08-12 |
human |
| George R Dakwar, Veronika Kaplun, Lena Kojukarov, Pavel Gorenbein, Ilana Schumacher, Diana Kontorovich, Carola Förster, Elie Beit-Yannai, David Stepensk. Toxicity assessment of extracts from infusion sets in cEND brain endothelial cells. International journal of pharmaceutics. vol 434. issue 1-2. 2013-01-04. PMID:22643027. |
cend cells were incubated with extracts of individual parts of the infusion sets (tube, cup, latex), and relative toxicities were analyzed using mtt test, dcfh-da-based analysis of reactive oxygen species formation, apoptosis and cell cycle analyses. |
2013-01-04 |
2023-08-12 |
mouse |
| Xiao-Ling Lu, Yan-Ling Zheng, Hai-Min Chen, Xiao-Jun Yan, Feng Wang, Wei-Feng X. [Anti-proliferation of human cervical cancer HeLa cell line by fascaplysin through apoptosis induction]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 44. issue 9. 2012-12-20. PMID:20055172. |
cytotoxic activity of fascaplysin on hela cells was determined using mtt assay, cell cycle analysis, and apoptosis (annexin v-fitc and pi double staining) studies. |
2012-12-20 |
2023-08-12 |
human |
| Yu-Ye Shi, Wei-Ke Cao, Xiao-Ning Liu, Zhi-Kui Deng, Hua Guo, Wan-Ting Feng, Li-Lin Ye, Jia-Bing Zhu, Yu-Feng L. [Effects of interferon-α combined with homoharringtonine on K562 cell proliferation and β-catenin expression]. Zhongguo shi yan xue ye xue za zhi. vol 20. issue 1. 2012-12-20. PMID:22391162. |
the proliferation, apoptosis, cell cycle and β-catenin mrna expression of k562 cells treated with ifn-α and/or hht were assayed with mtt, flow cytometry or rt-pcr respectively. |
2012-12-20 |
2023-08-12 |
Not clear |
| Jia Xie, Mei Zhang, Yan-Ping Song, Kai Hu, Jing-Jing Ren, Yun-Jie Zhan. [Caspase-independent apoptosis induced by arsenic trioxide in human multiple myeloma cell RPMI8226]. Zhongguo shi yan xue ye xue za zhi. vol 20. issue 1. 2012-12-20. PMID:22391177. |
mtt method was used to analyze the proliferation inhibition rate; flow cytometry was used to detect the apoptosis rate; western blot was used to determine the expressions of bcl-2 and caspase-3 in rpmi8226 cells. |
2012-12-20 |
2023-08-12 |
human |
| Mei Zeng, Wei-Ying Gu, Ting-Xiu Jiang, Zi-Xing Chen, Guo-Qiang Qiu, Man Li, Hao-Qing Wu, Zhi-Lin Wang, Xiao-Bao Xie, Xiang-Shan Ca. [Effects of simvastatin on PI3K/AKT signaling pathway in human acute monocytic leukemia cell line SHI-1]. Zhongguo shi yan xue ye xue za zhi. vol 20. issue 2. 2012-12-20. PMID:22541079. |
mtt method was used to assay the growth inhibition rate and flow cytometry was used to detect the early stage apoptosis ratio. |
2012-12-20 |
2023-08-12 |
human |
| Yang Yang, Hong-Juan Dong, Guang-Xun Gao, Yi-Wei Wang, Hong-Tao Gu, Xie-Qun Che. [Effects of triptolide on bortezomib-induced apoptosis in multiple myeloma cells]. Zhongguo shi yan xue ye xue za zhi. vol 20. issue 2. 2012-12-20. PMID:22541093. |
mtt assay was applied to detect the inhibitory effects of triptolide and bortezomib alone or combined at different concentrations on h929 cells, the cell apoptosis was assayed by flow cytometry with annexin v-fitc/pi staining. |
2012-12-20 |
2023-08-12 |
Not clear |
| Xiao Zhou, Yong-Ping Zhai, Jian-Gang Mei, Zhi-Ming An, Xiao-Gang Zhou, Ping Shi, Ya-Ping Yu, Hai-Ning Liu, Ping Son. [Relationship between the catalysis of Bence Jones protein and renal impairment in patients with multiple myeloma]. Zhongguo shi yan xue ye xue za zhi. vol 20. issue 2. 2012-12-20. PMID:22541094. |
the llc-pk1 cells were cultured with different concentration of bjp for 24 h, then proliferation of the cells were determined by mtt method and apoptosis were determined by flow cytometry. |
2012-12-20 |
2023-08-12 |
cat |
| Lihong Bu, Jin Xie, Kai Chen, Jing Huang, Zoraida P Aguilar, Andrew Wang, Kin Wai Sun, Mei-Sze Chua, Samuel So, Zhen Cheng, Henry S Eden, Baozhong Shen, Xiaoyuan Che. Assessment and comparison of magnetic nanoparticles as MRI contrast agents in a rodent model of human hepatocellular carcinoma. Contrast media & molecular imaging. vol 7. issue 4. 2012-12-20. PMID:22649042. |
mtt, apoptosis and cyclin/dna flow cytometry assays showed that the polymer coated nanoparticles had no adverse effect on cell growth. |
2012-12-20 |
2023-08-12 |
mouse |
| Ting-Yun Cui, Bao-An Chen, Jia-Hua Ding, Chong Gao, Jian Cheng, Wen Bao, Yue-Jiao Zhong, Xue-Yun Shan, Feng Gao, Guo-Hua Xia, Anita Schmitt, Michael Schmit. [Inducing apoptosis and reversal effect of nilotinib in combination with tetrandrine on multidrug resistance of K562/A02 cell line]. Zhongguo shi yan xue ye xue za zhi. vol 19. issue 1. 2012-12-17. PMID:21362216. |
methyl-thiazol tetrazolium (mtt) assay was employed to examine the pharmacological effect of nilotinib or tet alone on k562/a02 cell line, the ic(50) of daunorubicin (dnr) on k562/a02 cell line treated with nilotinib and tet was calculated; the flow cytometry (fcm) was employed to detect the apoptosis rate of k562/a02. |
2012-12-17 |
2023-08-12 |
Not clear |
| Hui-Ling Shen, Li-Li Fang, Chen Chen, Xin-Jian Fang, Qiao-Yun Chen, Juan Li, Wen-Lin X. [VEGF shRNA enhances the sensitivity of multidrug-resistant leukemia cells to anticancer agent]. Zhongguo shi yan xue ye xue za zhi. vol 19. issue 1. 2012-12-17. PMID:21362217. |
rt-pcr was used to detect the expression of vegf and mrp1 at the mrna level;western blot was used to analyze the expression of vegf, mrp1, akt, p-akt at the protein level; mtt was used to determine the ic(50) value of transfected cells to doxorubicin (dox); flow cytometry was used to detect cell apoptosis and intracellular rho123 retention. |
2012-12-17 |
2023-08-12 |
human |
| Ri-Bao Wei, Yong-Xin Wang, Li Cao, Li Zhuo, Bo Fu, Ping L. [Protective effect of compound tianpupian (TPP) against H(2)O(2)-induced apoptosis of murine splenic lymphocytes]. Zhongguo shi yan xue ye xue za zhi. vol 19. issue 1. 2012-12-17. PMID:21362254. |
the cell apoptosis rate was detected by mtt method; the cell apoptosis and mitochondrial membrance potential were detected by flow cytometry (fcm) with annexi-v/pi double staining and jc-1 staining method, respectively; and caspase 3 relative activity was determined by colorimetry. |
2012-12-17 |
2023-08-12 |
Not clear |
| Ning Lin, Hanbei Chen, Hongmei Zhang, Xiaoyu Wan, Qing S. Mitochondrial reactive oxygen species (ROS) inhibition ameliorates palmitate-induced INS-1 beta cell death. Endocrine. vol 42. issue 1. 2012-12-13. PMID:22350662. |
cell viability and apoptosis were measured by mtt and elisa; ros was detected by the probe dcfh-da and mitosox red using flow cytometer; and the er stress-related chaperones were measured by western blotting and real time pcr. |
2012-12-13 |
2023-08-12 |
Not clear |
| Xiu-Li Hong, Ze-Chuan Zhang, Jiang-Ning Zhao, Quan-Yi L. [Inhibitory effect of phenylhexyl isothiocyanate on notch signaling of multiple myeloma cells in vitro]. Zhongguo shi yan xue ye xue za zhi. vol 19. issue 4. 2012-12-11. PMID:21867619. |
the inhibition of proliferation was measured by mtt test and the cell apoptosis was assayed by dapi staining. |
2012-12-11 |
2023-08-12 |
Not clear |
| Bangmin Liu, Zhe Jian, Qiang Li, Kai Li, Zhiyong Wang, Ling Liu, Lingzhen Tang, Xiuli Yi, Hua Wang, Chunying Li, Tianwen Ga. Baicalein protects human melanocytes from H₂O₂-induced apoptosis via inhibiting mitochondria-dependent caspase activation and the p38 MAPK pathway. Free radical biology & medicine. vol 53. issue 2. 2012-12-11. PMID:22569306. |
melanocytes from the pig1 cell line were pretreated with different concentrations of be for 1 h, followed by exposure to 1.0 mm h(2)o(2) for 24 h. cell apoptosis, reactive oxygen species levels, and mitochondrial membrane potentials were evaluated by flow cytometry, and cell viability was determined by an mtt assay. |
2012-12-11 |
2023-08-12 |
human |
| Seung Hyun Oh, Young Mi Whang, Hye-Young Min, Seung Ho Han, Ju-Hee Kang, Ki-Hoon Song, Bonnie S Glisson, Yeul Hong Kim, Ho-Young Le. Histone deacetylase inhibitors enhance the apoptotic activity of insulin-like growth factor binding protein-3 by blocking PKC-induced IGFBP-3 degradation. International journal of cancer. vol 131. issue 10. 2012-12-10. PMID:22362554. |
the effects of the combination of rigfbp-3 and a number of hdac inhibitors on cell proliferation and apoptosis were assessed in vitro and in vivo by using the mtt assay, a flow cytometry-based tunel assay, western blot analyses and the nsclc xenograft tumor model. |
2012-12-10 |
2023-08-12 |
Not clear |
| Haiyan Lou, Xu Jing, Dongmei Ren, Xinbing Wei, Xiumei Zhan. Eriodictyol protects against H(2)O(2)-induced neuron-like PC12 cell death through activation of Nrf2/ARE signaling pathway. Neurochemistry international. vol 61. issue 2. 2012-12-07. PMID:22609376. |
the results showed that h(2)o(2)-induced cell death can be inhibited in the presence of eriodictyol as measured by assays for mtt and apoptosis. |
2012-12-07 |
2023-08-12 |
rat |
| Yan-Ling Ren, Hong-Yan Ton. [Effect of homoharringtonine combined with AG490 on JAK2-STAT5 associated signal pathway in HEL cells]. Zhongguo shi yan xue ye xue za zhi. vol 19. issue 5. 2012-12-06. PMID:22040954. |
the cell survival rates were tested by mtt, apoptosis was tested by flow cytometry after hel cells were treated by 20 ng/ml hht, 100 µmol/l ag490 and 20 ng/ml hht in combination with 100 µmol/l ag490, while the signal proteins such as p-jak2, p-stat5 and bcl-xl activated by abnormal activated jak2 were tested by western blot. |
2012-12-06 |
2023-08-12 |
Not clear |
| Xu-Chun He, Jian-Da H. [Effects of emodin on human erythroleukemia cell line HEL]. Zhongguo shi yan xue ye xue za zhi. vol 19. issue 5. 2012-12-06. PMID:22040955. |
the proliferation inhibition was detected by mtt method; the change of morphology was observed by ao/eb stains; the cell cycle and apoptosis was analyzed by flow cytometry; the expressions of akt, p-akt, p-gsk3β and hsp70 proteins were determined by western blot. |
2012-12-06 |
2023-08-12 |
human |