| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yi Zhou, Yongzhong Li, Jing Chen, Kai Mei, Mingxiang Kang, Ping Chen, Qiu L. Matrix protein of vesicular stomatitis virus targets the mitochondria, reprograms glucose metabolism，and sensitizes to 2-deoxyglucose in glioblastoma. Human gene therapy. 2024-07-13. PMID:39001830. |
when combined with 2-dg, vsv mp synergistically aggravated cell viability, apoptosis and g2/m phase arrest. |
2024-07-13 |
2024-07-16 |
Not clear |
| Wei Zhao, Zhenshan Jia, William A Bauman, Yiwen Qin, Yuanzhen Peng, Zihao Chen, Christopher P Cardozo, Dong Wang, Weiping Qi. Targeted-delivery of nanomedicine-enabled methylprednisolone to injured spinal cord promotes neuroprotection and functional recovery after acute spinal cord injury in rats. Nanomedicine : nanotechnology, biology, and medicine. 2024-06-13. PMID:38871068. |
our in vivo data reveal that nano-mp is significantly more effective than free mp in attenuating secondary injuries and neuronal apoptosis. |
2024-06-13 |
2024-06-16 |
human |
| Qian Wu, Rui Li, Yifei You, Wei Cheng, Yan Li, Yan Feng, Yuqin Fan, Yan Wan. Lung microbiota participated in fibrous microplastics (MPs) aggravating OVA-induced asthma disease in mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2024-06-08. PMID:38851522. |
in addition, mp fibers exposure induced lung epithelial cells apoptosis, disruption of epithelial barrier integrity and activation of nlrp3 related signaling pathways. |
2024-06-08 |
2024-06-11 |
mouse |
| Yaru Huang, Wenying Chi, Yan Li, Chengzhen Zhang, Junfa Li, Fanjun Men. Morphine Preconditioning Alleviates Ischemia/Reperfusion-induced Caspase-8-dependent Neuronal Apoptosis through cPKCγ-NF-κB-cFLIPL Pathway. Journal of neurosurgical anesthesiology. 2024-04-05. PMID:38577840. |
however, the mechanism of mp on the ischemia/reperfusion-induced neuronal apoptosis has not been fully clarified. |
2024-04-05 |
2024-04-07 |
Not clear |
| Wencan Zhang, Mingshan Liu, Jie Ren, Shuwei Han, Xiaolong Zhou, Dapeng Zhang, Xianzheng Guo, Haiwen Feng, Lei Ye, Shiqing Feng, Xizi Song, Lin Jin, Zhijian We. Magnetic Nanoparticles and Methylprednisolone Based Physico-Chemical Bifunctional Neural Stem Cells Delivery System for Spinal Cord Injury Repair. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2024-03-22. PMID:38516757. |
the delivery system releases mp to promote microglial m2 polarization, inhibit m1 polarization, and reduce neuronal apoptosis. |
2024-03-22 |
2024-03-24 |
mouse |
| Sasha Coates-Park, Joshua A Rich, William G Stetler-Stevenson, David Peene. The TIMP protein family: diverse roles in pathophysiology. American journal of physiology. Cell physiology. vol 326. issue 3. 2024-03-05. PMID:38284123. |
their functions however are not limited to mp inhibition, with each family member harboring numerous mp-independent biological functions that play key roles in processes such as inflammation and apoptosis. |
2024-03-05 |
2024-03-07 |
Not clear |
| Guilin Wang, Jun Mi, Jiangtao Bai, Qiqi He, Xiaoran Li, Zhiping Wan. Non-Coding RNAs in Kidney Stones. Biomolecules. vol 14. issue 2. 2024-02-24. PMID:38397450. |
mirnas have been studied quite extensively in nephrolithiasis, and a plethora of specific mirnas have been implicated in the pathogenesis of nephrolithiasis, involving remarkable changes in calcium metabolism, oxalate metabolism, oxidative stress, cell-crystal adhesion, cellular autophagy, apoptosis, and macrophage (mp) polarization and metabolism. |
2024-02-24 |
2024-02-26 |
Not clear |
| Nhu Thi Quynh Mai, Ulziituya Batjargal, Won-Seok Kim, Ji-Hoon Kim, Ji-Won Park, Ihn-Sil Kwak, Byoung-San Moo. Microplastic induces mitochondrial pathway mediated cellular apoptosis in mussel (Mytilus galloprovincialis) via inhibition of the AKT and ERK signaling pathway. Cell death discovery. vol 9. issue 1. 2023-12-06. PMID:38057300. |
furthermore, analysis of transcriptional activities of key genes for apoptosis of 100 mg/l-day 14 groups revealed the upregulation of both intrinsic and extrinsic apoptotic induction pathway and increment in gene transcripts involving genotoxic stress and energy metabolism according to mp morphotypes. |
2023-12-06 |
2023-12-10 |
Not clear |
| Tian Gan, Jianwei Yu, Jun H. miRNA, lncRNA and circRNA: targeted molecules with therapeutic promises in Mycoplasma pneumoniae infection. Archives of microbiology. vol 205. issue 8. 2023-07-21. PMID:37477725. |
this article reviews the mechanisms by which mirnas, lncrnas, and circrnas mediate mp infection, such as inflammatory responses, apoptosis and pulmonary fibrosis. |
2023-07-21 |
2023-08-14 |
Not clear |
| Yuting Shao, Yuxing Wang, Xin Hua, Yunhui Li, Dayong Wan. Polylactic acid microparticles in the range of μg/L reduce reproductive capacity by affecting the gonad development and the germline apoptosis in Caenorhabditis elegans. Chemosphere. 2023-06-14. PMID:37315859. |
in addition, exposure to 10 and 100 μg/l pla mp enhanced germline apoptosis in the gonad. |
2023-06-14 |
2023-08-14 |
caenorhabditis_elegans |
| Yuting Shao, Yuxing Wang, Xin Hua, Yunhui Li, Dayong Wan. Polylactic acid microparticles in the range of μg/L reduce reproductive capacity by affecting the gonad development and the germline apoptosis in Caenorhabditis elegans. Chemosphere. 2023-06-14. PMID:37315859. |
accompanied with the enhancement in germline apoptosis, exposure to 10 and 100 μg/l pla mp decreased expression of ced-9 and increased expressions of ced-3, ced-4, and egl-1. |
2023-06-14 |
2023-08-14 |
caenorhabditis_elegans |
| Yuting Shao, Yuxing Wang, Xin Hua, Yunhui Li, Dayong Wan. Polylactic acid microparticles in the range of μg/L reduce reproductive capacity by affecting the gonad development and the germline apoptosis in Caenorhabditis elegans. Chemosphere. 2023-06-14. PMID:37315859. |
moreover, the induction of germline apoptosis in pla mp exposed nematodes was suppressed by rnai of ced-3, ced-4, and egl-1, and strengthened by rnai of ced-9. |
2023-06-14 |
2023-08-14 |
caenorhabditis_elegans |
| Wenqi Fu, Yeong-Gwan Im, Byunggook Kim, Ok-Su Kim, Ying Yang, Jianan Song, Danyang Liu, Siyu Zhu, Jae-Seok Kang, Okjoon Ki. 625 nm Light Irradiation Prevented MC3T3-E1 Cells from Accumulation of Misfolded Proteins via ROS and ATP Production. International journal of molecular sciences. vol 24. issue 11. 2023-06-11. PMID:37298212. |
mp accumulation contributes to cellular apoptosis and bone disorders. |
2023-06-11 |
2023-08-14 |
Not clear |
| Michele Aramburu Serafini, Dienifer Hermann Sirena, Ana Beatriz Tittoni da Silveira, Monique Franco-da-Silva, Mariana Rauback Aubin, Tuane Nerissa Alves Garcez, Anelise Araújo, Fernanda Dos Santos Pereira, Martin J Hoogduijn, Fabiany da Costa Gonçalves, Ana Helena Pa. Mesenchymal stromal cell-derived membrane particles: A novel cell-free therapy for inflammatory bowel diseases. International immunopharmacology. vol 118. 2023-04-08. PMID:37030123. |
our findings revealed that mp, cm, and living msc ameliorated dss-induced colitis by reducing colonic inflammation, the loss of colonic goblet cells, and intestinal mucosa permeability, preventing apoptosis of damaged colonic cells and balancing th1 and th2 activity. |
2023-04-08 |
2023-08-14 |
mouse |
| Chaofan Sun, Jia Teng, Dongyu Wang, Jianmin Zhao, Encui Shan, Qing Wan. The adverse impact of microplastics and their attached pathogen on hemocyte function and antioxidative response in the mussel Mytilus galloprovincialis. Chemosphere. 2023-03-12. PMID:36907490. |
coexposure can induce hemocytes to produce higher ros, improve phagocytosis, significantly reduce the stability of the lysosome membrane, and induce the expression of apoptosis-related genes, causing apoptosis of hemocytes compared with single mp exposure. |
2023-03-12 |
2023-08-14 |
human |
| Tianyi Chen, Haoze Chen, Anli Wang, Weixuan Yao, Zhongshi Xu, Binjie Wang, Jiye Wang, Yuanzhao W. Methyl Parathion Exposure Induces Development Toxicity and Cardiotoxicity in Zebrafish Embryos. Toxics. vol 11. issue 1. 2023-01-20. PMID:36668810. |
exposure to mp resulted in the accumulation of reactive oxygen species (ros), decreased superoxide dismutase (sod) activity, increased catalase (cat) activity, elevated malondialdehyde (mda) levels, and caused cardiac apoptosis in zebrafish embryos. |
2023-01-20 |
2023-08-14 |
cat |
| Yaling Yu, Lishan Lin, Kangping Liu, Yixin Jiang, Zhenlei Zho. Effects of Simvastatin on Cartilage Homeostasis in Steroid-Induced Osteonecrosis of Femoral Head by Inhibiting Glucocorticoid Receptor. Cells. vol 11. issue 24. 2022-12-23. PMID:36552711. |
furthermore, mp treatment induced apoptosis and high-level catabolism and low-level anabolism in vitro and vivo, while simvastatin significantly decreased catabolism and slightly recovered anabolism via inhibiting gr and the hypoxia-inducible factor (hif) pathway. |
2022-12-23 |
2023-08-14 |
Not clear |
| Andry Ny Aina Rabezanahary, Mathilde Piette, Omayma Missawi, Mutien- Marie Garigliany, Patrick Kestemont, Cornet Valéri. Microplastics alter development, behavior, and innate immunity responses following bacterial infection during zebrafish embryo-larval development. Chemosphere. 2022-10-28. PMID:36306963. |
our results indicated a difference in immune system (nfkb, il1β) and apoptosis (casp3a, bcl2) related gene expression depending on the timing of mp exposure, which highlighted a contrasting sensitivity according to the exposure time in mp studies. |
2022-10-28 |
2023-08-14 |
zebrafish |
| Wei Fang, Jingyu Huang, Jun Wang, Tengyi Huang, Dajia Lin, Jun Yi. Blockade of interleukin-6 receptor attenuates apoptosis and modulates the inflammatory response in Mycoplasma pneumoniae infected A549 cells. American journal of translational research. vol 14. issue 9. 2022-10-17. PMID:36247299. |
to investigate the effect of silencing the interleukin (il)-6 gene on the induction of inflammation, oxidative stress and apoptosis in mycoplasma pneumoniae (mp) infected a549 cells and its mechanism of action. |
2022-10-17 |
2023-08-14 |
Not clear |
| Li-Tzu Huang, Chin-Ho Kuo, Lin Tseng, Yi-Syuan Li, Li-Hsin Cheng, Chin-Yun Cheng, Shane-Rong Sheu, Wen-Tsan Chang, Chien-Chin Chen, Hung-Chi Chen. Alpha-Mangostin Reduces Pericellular Fibronectin on Suspended Tumor Cells and Therapeutically, but Not Prophylactically, Suppresses Distant Metastasis. Life (Basel, Switzerland). vol 12. issue 9. 2022-09-23. PMID:36143411. |
immunofluorescence staining, mtt assays, flow cytometric assays, immunoblotting, and experimental metastasis mouse models were used to detect the effects of mp extracts or α-mg on perifn on stcs, tumor cell proliferation and apoptosis, the akt activity, and tumor lung metastasis. |
2022-09-23 |
2023-08-14 |
mouse |