| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Benharroch, A Levy, I Prinsloo, S Ariad, D Rabinovitch, Y Shendler, M Sacks, J Gopa. Apoptotic index as a prognostic factor in Hodgkin's disease. Leukemia & lymphoma. vol 33. issue 3-4. 1999-06-10. PMID:10221515. |
a retrospective study of 92 patients was carried out, using in situ end labelling of dna fragments and an apoptosis detection kit. |
1999-06-10 |
2023-08-12 |
Not clear |
| K C Fang, P J Wolters, M Steinhoff, A Bidgol, J L Blount, G H Caughe. Mast cell expression of gelatinases A and B is regulated by kit ligand and TGF-beta. Journal of immunology (Baltimore, Md. : 1950). vol 162. issue 9. 1999-05-20. PMID:10228034. |
the profibrotic cytokine tgf-beta virtually abolishes the gelatinase b mrna signal and also attenuates kit ligand-mediated induction of gelatinase b expression, suggesting that an excess of tgf-beta in inflamed or injured tissues may alter mast cell expression of gelatinase b, which is implicated in extracellular matrix degradation, angiogenesis, and apoptosis. |
1999-05-20 |
2023-08-12 |
dog |
| G Silvestrini, P Mocetti, P Ballanti, R Di Grezia, E Bonucc. In vivo incidence of apoptosis evaluated with the TdT FragEL DNA fragmentation detection kit in cartilage and bone cells of the rat tibia. Tissue & cell. vol 30. issue 6. 1999-03-29. PMID:10036787. |
in vivo incidence of apoptosis evaluated with the tdt fragel dna fragmentation detection kit in cartilage and bone cells of the rat tibia. |
1999-03-29 |
2023-08-12 |
rat |
| T Aotake, C D Lu, Y Chiba, R Muraoka, N Tanigaw. Changes of angiogenesis and tumor cell apoptosis during colorectal carcinogenesis. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 5. issue 1. 1999-03-24. PMID:9918211. |
seeking a potential correlation, we investigated tumor cell apoptosis, proliferation, and angiogenesis in the adenoma-carcinoma sequence of colorectal carcinogenesis using an in situ apoptosis detection kit and mib-1 and anti-cd34 antibodies in 27 adenomas with low dysplasia, 17 adenomas with high dysplasia, and 26 carcinomas in adenoma, as well as assessed p53 and bcl-2 expressions. |
1999-03-24 |
2023-08-12 |
Not clear |
| C J Koch, J E Chasan, W T Jenkins, C Y Chan, K M Laughlin, S M Evan. Co-localization of hypoxia and apoptosis in irradiated and untreated HCT116 human colon carcinoma xenografts. Advances in experimental medicine and biology. vol 454. 1999-01-28. PMID:9889941. |
apoptosis was assessed using a commercial kit which stains damaged dna. |
1999-01-28 |
2023-08-12 |
mouse |
| I Timokhina, H Kissel, G Stella, P Besme. Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation. The EMBO journal. vol 17. issue 21. 1999-01-11. PMID:9799234. |
in mast cells, kit receptor activation mediates several cellular responses including cell proliferation and suppression of apoptosis induced by growth factor deprivation and gamma-irradiation. |
1999-01-11 |
2023-08-12 |
Not clear |
| I Timokhina, H Kissel, G Stella, P Besme. Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation. The EMBO journal. vol 17. issue 21. 1999-01-11. PMID:9799234. |
analysis of bmmc expressing wild-type and dominant-negative mutant forms of rac1 and jnk revealed that the rac1/jnk pathway is critical for kit ligand (kl)-induced proliferation of mast cells but not for suppression of apoptosis. |
1999-01-11 |
2023-08-12 |
Not clear |
| N Maulik, T Yoshida, R M Engelman, D Deaton, J E Flack, J A Rousou, D K Da. Ischemic preconditioning attenuates apoptotic cell death associated with ischemia/reperfusion. Molecular and cellular biochemistry. vol 186. issue 1-2. 1998-12-30. PMID:9774195. |
apoptosis was studied by visualizing the apoptotic cardiomyocytes by direct fluorescence detection of digoxigenin-labeled genomic dna using apoptag in situ apoptosis detection kit. |
1998-12-30 |
2023-08-12 |
rat |
| J Kumi-Diaka, R Rodriguez, G Goudaz. Influence of genistein (4',5,7-trihydroxyisoflavone) on the growth and proliferation of testicular cell lines. Biology of the cell. vol 90. issue 4. 1998-11-30. PMID:9800352. |
a second series of experiments were performed to determine the degree of genistein-induced apoptosis in these cells, using apop-tag kit reagents, to detect apoptotic cells in situ by specific end labeling, and detection of dna fragments produced by the apoptotic process. |
1998-11-30 |
2023-08-12 |
Not clear |
| J M Le. Inhibition of p53-dependent apoptosis by the KIT tyrosine kinase: regulation of mitochondrial permeability transition and reactive oxygen species generation. Oncogene. vol 17. issue 13. 1998-11-17. PMID:9796694. |
inhibition of p53-dependent apoptosis by the kit tyrosine kinase: regulation of mitochondrial permeability transition and reactive oxygen species generation. |
1998-11-17 |
2023-08-12 |
mouse |
| J M Le. Inhibition of p53-dependent apoptosis by the KIT tyrosine kinase: regulation of mitochondrial permeability transition and reactive oxygen species generation. Oncogene. vol 17. issue 13. 1998-11-17. PMID:9796694. |
kit regulates these diverse processes, at least in part, by inhibiting apoptosis. |
1998-11-17 |
2023-08-12 |
mouse |
| J M Le. Inhibition of p53-dependent apoptosis by the KIT tyrosine kinase: regulation of mitochondrial permeability transition and reactive oxygen species generation. Oncogene. vol 17. issue 13. 1998-11-17. PMID:9796694. |
we have previously found that kit can suppress p53-mediated apoptosis. |
1998-11-17 |
2023-08-12 |
mouse |
| J M Le. Inhibition of p53-dependent apoptosis by the KIT tyrosine kinase: regulation of mitochondrial permeability transition and reactive oxygen species generation. Oncogene. vol 17. issue 13. 1998-11-17. PMID:9796694. |
the mechanism by which kit suppresses apoptosis is, however, uncharacterized. |
1998-11-17 |
2023-08-12 |
mouse |
| J M Le. Inhibition of p53-dependent apoptosis by the KIT tyrosine kinase: regulation of mitochondrial permeability transition and reactive oxygen species generation. Oncogene. vol 17. issue 13. 1998-11-17. PMID:9796694. |
kit activation suppresses p53-induced apoptosis in the mouse dp16 friend erythroleukemia cell line by preventing delta(psi)m depolarization and ros generation. |
1998-11-17 |
2023-08-12 |
mouse |
| J M Le. Inhibition of p53-dependent apoptosis by the KIT tyrosine kinase: regulation of mitochondrial permeability transition and reactive oxygen species generation. Oncogene. vol 17. issue 13. 1998-11-17. PMID:9796694. |
thus, the kit kinase prevents apoptosis by regulating mitochondrial function and cellular redox state. |
1998-11-17 |
2023-08-12 |
mouse |
| G W Krystal, C S DeBerry, D Linnekin, J Lit. Lck associates with and is activated by Kit in a small cell lung cancer cell line: inhibition of SCF-mediated growth by the Src family kinase inhibitor PP1. Cancer research. vol 58. issue 20. 1998-11-06. PMID:9788619. |
these data demonstrate that, in the h526 sclc cell line, lck and, possibly, yes are downstream of kit in a signal transduction pathway; the inhibition by pp1 of scf-mediated proliferation and inhibition of apoptosis suggests that src family kinases are intermediates in the signaling pathways that regulate these processes. |
1998-11-06 |
2023-08-12 |
Not clear |
| G Sarli, L Della Salda, L Zaccaro, M Bendinelli, G Piedimonte, P S Marcat. Apoptotic fraction in lymphoid tissue of FIV-infected SPF cats. Veterinary immunology and immunopathology. vol 64. issue 1. 1998-09-23. PMID:9656429. |
apoptosis in lymphoid tissue was revealed with the apoptag-peroxidase kit, quantified by image analysis and expressed as apoptotic index (number of apoptosis per 100 cells). |
1998-09-23 |
2023-08-12 |
Not clear |
| H W Yang, K J Hwang, H C Kwon, H S Kim, K W Choi, K S O. Detection of reactive oxygen species (ROS) and apoptosis in human fragmented embryos. Human reproduction (Oxford, England). vol 13. issue 4. 1998-08-06. PMID:9619561. |
the relative intensity of h2o2 concentrations within embryos was measured using 2',7'-dichlorodihydrofluorescein diacetate by quanti cell 500 fluorescence imaging and dna fragmentation was observed with transmission electron microscopy and an in-situ apoptosis detection kit. |
1998-08-06 |
2023-08-12 |
mouse |
| N Maulik, T Yoshida, D K Da. Oxidative stress developed during the reperfusion of ischemic myocardium induces apoptosis. Free radical biology & medicine. vol 24. issue 5. 1998-07-23. PMID:9586819. |
apoptosis was studied by visualizing the apoptotic cardiomyocytes by direct fluorescence detection of digoxigenin-labeled genomic dna using apoptag in situ apoptosis detection kit. |
1998-07-23 |
2023-08-12 |
rat |
| M Wagrowska-Danilewicz, M Danilewic. Apoptosis in lupus SLE-N IV and non-lupus mesangiocapillary glomerulonephritis type I MCGN. I. A comparative study. Journal of nephrology. vol 11. issue 1. 1998-06-04. PMID:9561485. |
we used an in situ cell death detection kit, pod, which detects single cell apoptosis in formalin-fixed renal tissue. |
1998-06-04 |
2023-08-12 |
Not clear |