| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Gheba. Normal hepatic growth: study of the proliferative capacity and apoptosis of the normal liver during childhood. Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. vol 3. issue 1. 2000-01-18. PMID:10594134. |
we explored the mechanism of normal hepatic growth in children by evaluating the proliferation index (with ki-67 antibody) and apoptosis index (with the apoptag kit). |
2000-01-18 |
2023-08-12 |
Not clear |
| J Daly, D K Lahiri, G J Kotwa. Examination of the interactions of the amyloid precursor protein carboxyl terminus to intracellular protein: possible role in apoptosis. Progress in neuro-psychopharmacology & biological psychiatry. vol 23. issue 5. 1999-12-02. PMID:10509380. |
the authors examined hippocampal tissue sections from alzheimer's disease (ad) and age-matched normal control patients for a difference in the number of apoptotic nuclei present using an in situ apoptosis detection kit that labels the numerous free dna ends present in apoptotic nuclei. |
1999-12-02 |
2023-08-12 |
human |
| S A Jordan, R M Speed, F Bernex, I J Jackso. Deficiency of Trp53 rescues the male fertility defects of Kit(W-v) mice but has no effect on the survival of melanocytes and mast cells. Developmental biology. vol 215. issue 1. 1999-12-02. PMID:10525351. |
we conclude that defective kit signaling in vivo results in apoptosis by a p53-independent pathway in melanocyte and mast cell lineages but that in male germ cells apoptosis in the absence of kit is p53-dependent. |
1999-12-02 |
2023-08-12 |
mouse |
| A Schmidt-Choudhury, J Meissner, J Seebeck, E J Goetzl, M Xia, S J Galli, W E Schmidt, J Schaub, B K Wershi. Stem cell factor influences neuro-immune interactions: the response of mast cells to pituitary adenylate cyclase activating polypeptide is altered by stem cell factor. Regulatory peptides. vol 83. issue 2-3. 1999-11-15. PMID:10511460. |
stem cell factor (scf), also known as c-kit or kit ligand, induces multiple effects on mast cells, including proliferation, differentiation, maturation, and prevents apoptosis. |
1999-11-15 |
2023-08-12 |
mouse |
| Y Bar-Dayan, A Afek, Y Bar-Dayan, I Goldberg, J Kopolovi. Proliferation, apoptosis and thymic involution. Tissue & cell. vol 31. issue 4. 1999-11-02. PMID:10522388. |
in situ detection of apoptosis of thymocytes was carried out using the apoptag kit, which can detect a single cell apoptosis. |
1999-11-02 |
2023-08-12 |
mouse |
| T Ito, S Fujieda, H Tsuzuki, H Sunaga, G Fan, C Sugimoto, M Fukuda, H Sait. Decreased expression of Bax is correlated with poor prognosis in oral and oropharyngeal carcinoma. Cancer letters. vol 140. issue 1-2. 1999-08-19. PMID:10403545. |
we investigated the expression of apoptosis-related factors, p53, bax, bcl-2, and spontaneous apoptosis in 57 cases of oral and oropharyngeal squamous cell carcinoma (scc) by immunochemical staining and apoptag kit. |
1999-08-19 |
2023-08-12 |
Not clear |
| L J Murray, J C Young, L J Osborne, K M Luens, R Scollay, B L Hil. Thrombopoietin, flt3, and kit ligands together suppress apoptosis of human mobilized CD34+ cells and recruit primitive CD34+ Thy-1+ cells into rapid division. Experimental hematology. vol 27. issue 6. 1999-07-01. PMID:10378891. |
thrombopoietin, flt3, and kit ligands together suppress apoptosis of human mobilized cd34+ cells and recruit primitive cd34+ thy-1+ cells into rapid division. |
1999-07-01 |
2023-08-12 |
human |
| M Ito, Y Kawa, H Ono, M Okura, T Baba, Y Kubota, S I Nishikawa, M Mizoguch. Removal of stem cell factor or addition of monoclonal anti-c-KIT antibody induces apoptosis in murine melanocyte precursors. The Journal of investigative dermatology. vol 112. issue 5. 1999-06-18. PMID:10233774. |
with an in situ apoptosis detection kit, a significant increase in apoptosis was detected after the removal of scf, which further increased with the addition of ack2 during scf-dependent periods. |
1999-06-18 |
2023-08-12 |
mouse |
| D Benharroch, A Levy, I Prinsloo, S Ariad, D Rabinovitch, Y Shendler, M Sacks, J Gopa. Apoptotic index as a prognostic factor in Hodgkin's disease. Leukemia & lymphoma. vol 33. issue 3-4. 1999-06-10. PMID:10221515. |
a retrospective study of 92 patients was carried out, using in situ end labelling of dna fragments and an apoptosis detection kit. |
1999-06-10 |
2023-08-12 |
Not clear |
| K C Fang, P J Wolters, M Steinhoff, A Bidgol, J L Blount, G H Caughe. Mast cell expression of gelatinases A and B is regulated by kit ligand and TGF-beta. Journal of immunology (Baltimore, Md. : 1950). vol 162. issue 9. 1999-05-20. PMID:10228034. |
the profibrotic cytokine tgf-beta virtually abolishes the gelatinase b mrna signal and also attenuates kit ligand-mediated induction of gelatinase b expression, suggesting that an excess of tgf-beta in inflamed or injured tissues may alter mast cell expression of gelatinase b, which is implicated in extracellular matrix degradation, angiogenesis, and apoptosis. |
1999-05-20 |
2023-08-12 |
dog |
| G Silvestrini, P Mocetti, P Ballanti, R Di Grezia, E Bonucc. In vivo incidence of apoptosis evaluated with the TdT FragEL DNA fragmentation detection kit in cartilage and bone cells of the rat tibia. Tissue & cell. vol 30. issue 6. 1999-03-29. PMID:10036787. |
in vivo incidence of apoptosis evaluated with the tdt fragel dna fragmentation detection kit in cartilage and bone cells of the rat tibia. |
1999-03-29 |
2023-08-12 |
rat |
| T Aotake, C D Lu, Y Chiba, R Muraoka, N Tanigaw. Changes of angiogenesis and tumor cell apoptosis during colorectal carcinogenesis. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 5. issue 1. 1999-03-24. PMID:9918211. |
seeking a potential correlation, we investigated tumor cell apoptosis, proliferation, and angiogenesis in the adenoma-carcinoma sequence of colorectal carcinogenesis using an in situ apoptosis detection kit and mib-1 and anti-cd34 antibodies in 27 adenomas with low dysplasia, 17 adenomas with high dysplasia, and 26 carcinomas in adenoma, as well as assessed p53 and bcl-2 expressions. |
1999-03-24 |
2023-08-12 |
Not clear |
| C J Koch, J E Chasan, W T Jenkins, C Y Chan, K M Laughlin, S M Evan. Co-localization of hypoxia and apoptosis in irradiated and untreated HCT116 human colon carcinoma xenografts. Advances in experimental medicine and biology. vol 454. 1999-01-28. PMID:9889941. |
apoptosis was assessed using a commercial kit which stains damaged dna. |
1999-01-28 |
2023-08-12 |
mouse |
| I Timokhina, H Kissel, G Stella, P Besme. Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation. The EMBO journal. vol 17. issue 21. 1999-01-11. PMID:9799234. |
in mast cells, kit receptor activation mediates several cellular responses including cell proliferation and suppression of apoptosis induced by growth factor deprivation and gamma-irradiation. |
1999-01-11 |
2023-08-12 |
Not clear |
| I Timokhina, H Kissel, G Stella, P Besme. Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation. The EMBO journal. vol 17. issue 21. 1999-01-11. PMID:9799234. |
analysis of bmmc expressing wild-type and dominant-negative mutant forms of rac1 and jnk revealed that the rac1/jnk pathway is critical for kit ligand (kl)-induced proliferation of mast cells but not for suppression of apoptosis. |
1999-01-11 |
2023-08-12 |
Not clear |
| N Maulik, T Yoshida, R M Engelman, D Deaton, J E Flack, J A Rousou, D K Da. Ischemic preconditioning attenuates apoptotic cell death associated with ischemia/reperfusion. Molecular and cellular biochemistry. vol 186. issue 1-2. 1998-12-30. PMID:9774195. |
apoptosis was studied by visualizing the apoptotic cardiomyocytes by direct fluorescence detection of digoxigenin-labeled genomic dna using apoptag in situ apoptosis detection kit. |
1998-12-30 |
2023-08-12 |
rat |
| J Kumi-Diaka, R Rodriguez, G Goudaz. Influence of genistein (4',5,7-trihydroxyisoflavone) on the growth and proliferation of testicular cell lines. Biology of the cell. vol 90. issue 4. 1998-11-30. PMID:9800352. |
a second series of experiments were performed to determine the degree of genistein-induced apoptosis in these cells, using apop-tag kit reagents, to detect apoptotic cells in situ by specific end labeling, and detection of dna fragments produced by the apoptotic process. |
1998-11-30 |
2023-08-12 |
Not clear |
| J M Le. Inhibition of p53-dependent apoptosis by the KIT tyrosine kinase: regulation of mitochondrial permeability transition and reactive oxygen species generation. Oncogene. vol 17. issue 13. 1998-11-17. PMID:9796694. |
inhibition of p53-dependent apoptosis by the kit tyrosine kinase: regulation of mitochondrial permeability transition and reactive oxygen species generation. |
1998-11-17 |
2023-08-12 |
mouse |
| J M Le. Inhibition of p53-dependent apoptosis by the KIT tyrosine kinase: regulation of mitochondrial permeability transition and reactive oxygen species generation. Oncogene. vol 17. issue 13. 1998-11-17. PMID:9796694. |
kit regulates these diverse processes, at least in part, by inhibiting apoptosis. |
1998-11-17 |
2023-08-12 |
mouse |
| J M Le. Inhibition of p53-dependent apoptosis by the KIT tyrosine kinase: regulation of mitochondrial permeability transition and reactive oxygen species generation. Oncogene. vol 17. issue 13. 1998-11-17. PMID:9796694. |
we have previously found that kit can suppress p53-mediated apoptosis. |
1998-11-17 |
2023-08-12 |
mouse |