| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Youhua Wei, Zhijun Wang, Li Wei, Shen Li, Xuemei Qiu, Chengwen Li. MicroRNA-874-3p promotes testosterone-induced granulosa cell apoptosis by suppressing HDAC1-mediated p53 deacetylation. Experimental and therapeutic medicine. vol 21. issue 4. 2021-03-20. PMID:33732332. |
mir-874-3p inhibitor failed to attenuate hdac1 overexpression-induced gc apoptosis. |
2021-03-20 |
2023-08-13 |
Not clear |
| Nastaran Injinari, Zeinab Amini-Farsani, Mahtab Yadollahi-Farsani, Hossein Teimor. Apoptotic effects of valproic acid on miR-34a, miR-520h and HDAC1 gene in breast cancer. Life sciences. vol 269. 2021-02-16. PMID:33453248. |
we evaluated the impact of vpa on the expression of mir-34a, mir-520h, and their target gene histone deacetylase 1 (hdac1), as well as their relationship with apoptosis in breast cancer. |
2021-02-16 |
2023-08-13 |
Not clear |
| Nastaran Injinari, Zeinab Amini-Farsani, Mahtab Yadollahi-Farsani, Hossein Teimor. Apoptotic effects of valproic acid on miR-34a, miR-520h and HDAC1 gene in breast cancer. Life sciences. vol 269. 2021-02-16. PMID:33453248. |
the anticancer impact of vpa on apoptosis and the expression levels of mir-34a, mir-520h, and hdac1 gene were measured in mcf-7 and mda-mb-231 cell lines. |
2021-02-16 |
2023-08-13 |
Not clear |
| Masumeh Sanaei, Fraidoon Kavoos. Investigation of the Effect of Zebularine in Comparison to and in Combination with Trichostatin A on p21Cip1/Waf1/ Sdi1, p27Kip1, p57Kip2, DNA Methyltransferases and Histone Deacetylases in Colon Cancer LS 180 Cell Line. Asian Pacific journal of cancer prevention : APJCP. vol 21. issue 6. 2021-02-11. PMID:32592383. |
the current study was designed to evaluate the effect of zebularine in comparison to and in combination with trichostatin a (tsa) on p21cip1/waf1/sdi1, p27kip1, p57kip2, dna methyltransferases (dnmt1, 3a and 3b) and histone deacetylases (hdac1, 2, and 3) genes expression, cell growth inhibition and apoptosis induction in colon cancer ls 180 cell line. |
2021-02-11 |
2023-08-13 |
Not clear |
| Hao Wang, Kazuo Sugimoto, Hao Lu, Wan-Yong Yang, Ji-Yue Liu, Hong-Yu Yang, Yue-Bo Song, Dong Yan, Tian-Yu Zou, Si She. HDAC1-mediated deacetylation of HIF1α prevents atherosclerosis progression by promoting miR-224-3p-mediated inhibition of FOSL2. Molecular therapy. Nucleic acids. vol 23. 2021-01-30. PMID:33510945. |
we intended to characterize functional relevance of microrna (mir)-224-3p in endothelial cell (ec) apoptosis and reactive oxygen species (ros) accumulation in atherosclerosis, considering also the integral involvement of histone deacetylase 1 (hdac1)-mediated hypoxia-inducible factor-1α (hif1α) deacetylation. |
2021-01-30 |
2023-08-13 |
Not clear |
| Li-Zhen Zhang, Jin-E Yang, Yu-Wei Luo, Feng-Ting Liu, Yun-Fei Yuan, Shi-Mei Zhuan. A p53/lnc-Ip53 Negative Feedback Loop Regulates Tumor Growth and Chemoresistance. Advanced science (Weinheim, Baden-Wurttemberg, Germany). vol 7. issue 21. 2020-11-13. PMID:33173727. |
furthermore, lnc-ip53 impedes p53 acetylation by interacting with histone deacetylase 1 (hdac1) and e1a binding protein p300 (p300) to prevent hdac1 degradation and attenuate p300 activity, resulting in abrogation of p53 activity and subsequent cell proliferation and apoptosis resistance. |
2020-11-13 |
2023-08-13 |
mouse |
| S V Demyanenko, V A Dzreyan, M A Neginskaya, A B Uzdensk. Expression of Histone Deacetylases HDAC1 and HDAC2 and Their Role in Apoptosis in the Penumbra Induced by Photothrombotic Stroke. Molecular neurobiology. vol 57. issue 1. 2020-10-07. PMID:31493239. |
expression of histone deacetylases hdac1 and hdac2 and their role in apoptosis in the penumbra induced by photothrombotic stroke. |
2020-10-07 |
2023-08-13 |
rat |
| Ting-Yi Sun, Hong-Jian Xie, Zhen Li, Ling-Fei Kong, Xiang-Nan Gou, Du-Juan Li, Yu-Jie Shi, Yan-Zhi Din. miR-34a regulates HDAC1 expression to affect the proliferation and apoptosis of hepatocellular carcinoma. American journal of translational research. vol 9. issue 1. 2020-10-01. PMID:28123637. |
mir-34a regulates hdac1 expression to affect the proliferation and apoptosis of hepatocellular carcinoma. |
2020-10-01 |
2023-08-13 |
Not clear |
| Zhiqiang Yu, Jun Zeng, Hui Liu, Tian Wang, Ziqi Yu, Jianyong Che. Role of HDAC1 in the progression of gastric cancer and the correlation with lncRNAs. Oncology letters. vol 17. issue 3. 2020-10-01. PMID:30867763. |
silencing of hdac1 decreased the proliferation and increased the apoptosis of sc-m1 cell lines, but had no effect on the migration of the sc-m1 cell lines. |
2020-10-01 |
2023-08-13 |
Not clear |
| Baojie Zhang, Bin Liu, Deng Chen, Rita Setroikromo, Hidde J Haisma, Wim J Qua. Histone Deacetylase Inhibitors Sensitize TRAIL-Induced Apoptosis in Colon Cancer Cells. Cancers. vol 11. issue 5. 2020-10-01. PMID:31083396. |
our data show that trail-mediated apoptosis is largely improved in widr cells by pre-incubation with entinostat-a hdac1, 2, and 3 inhibitor- and in dld-1 cells by rgfp966-a hdac3-specific inhibitor- or pci34051-a hdac8-specific inhibitor. |
2020-10-01 |
2023-08-13 |
Not clear |
| Masumeh Sanaei, Fraidoon Kavoos. Effect of 5-Aza-2'-Deoxycytidine in Comparison to Valproic Acid and Trichostatin A on Histone Deacetylase 1, DNA Methyltransferase 1, and CIP/KIP Family (p21, p27, and p57) Genes Expression, Cell Growth Inhibition, and Apoptosis Induction in Colon Cancer SW480 Cell Line. Advanced biomedical research. vol 8. 2020-10-01. PMID:31516890. |
the aim of the present study was to investigate the effect of 5-aza-2'-deoxycytidine (5-aza-cdr) in comparison to valproic acid (vpa) and trichostatin a (tsa) on hdac1, dnmt1, and cip/kip family (p21, p27, and p57) genes expression, cell growth inhibition, and apoptosis induction in colon cancer sw480 cell line. |
2020-10-01 |
2023-08-13 |
Not clear |
| Yi Zhang, Jie Chen, Shan-Shan Wu, Meng-Jiao Lv, Yong-Sheng Yu, Zheng-Hao Tang, Xiao-Hua Chen, Guo-Qing Zan. HOXA10 knockdown inhibits proliferation, induces cell cycle arrest and apoptosis in hepatocellular carcinoma cells through HDAC1. Cancer management and research. vol 11. 2020-09-29. PMID:31440094. |
hoxa10 knockdown inhibits proliferation, induces cell cycle arrest and apoptosis in hepatocellular carcinoma cells through hdac1. |
2020-09-29 |
2023-08-13 |
human |
| Xiao-Li Li, Mei Hon. Aqueous extract of Dendrobium officinale confers neuroprotection against hypoxic-ischemic brain damage in neonatal rats. The Kaohsiung journal of medical sciences. vol 36. issue 1. 2020-06-08. PMID:31642199. |
the neonatal rat models of hibd presented impaired neurobehaviors and antioxidant capacity, increased neuronal apoptosis and expression of hif-1α and histone deacetylase 1 (hdac1), as well as diminished expression of neurotrophic factors and k |
2020-06-08 |
2023-08-13 |
rat |
| Jin-Feng Li, Ying-Shu Li, Yi-Yang Zhang, Shu-Feng Sun, Tie-Sheng Han, Yu-Hong Li, Fu-Min Fen. Regulation of P300 and HDAC1 on endoplasmic reticulum stress in isoniazid-induced HL-7702 hepatocyte injury. Journal of cellular physiology. 2019-11-20. PMID:30786008. |
endoplasmic reticulum stress (ers) is one of the main pathways of apoptosis and is activated during inflammatory responses, but the roles of p300 and hdac1 in ers in antituberculosis drug-induced liver injury (adli) are not clear. |
2019-11-20 |
2023-08-13 |
Not clear |
| Jin-Feng Li, Ying-Shu Li, Yi-Yang Zhang, Shu-Feng Sun, Tie-Sheng Han, Yu-Hong Li, Fu-Min Fen. Regulation of P300 and HDAC1 on endoplasmic reticulum stress in isoniazid-induced HL-7702 hepatocyte injury. Journal of cellular physiology. 2019-11-20. PMID:30786008. |
this study confirms that isoniazid can change the states of p300 and hdac1 in hl-7702 hepatocyte metabolism and induce ers, causing hepatocyte injury and apoptosis. |
2019-11-20 |
2023-08-13 |
Not clear |
| Zhen Zhou, Qin Fang, Peifan Li, Dan Ma, Nana Zhe, Mei Ren, Bingqing Chen, Zhengchang He, Jun Wang, Qin Zhong, Jishi Wan. Entinostat combined with Fludarabine synergistically enhances the induction of apoptosis in TP53 mutated CLL cells via the HDAC1/HO-1 pathway. Life sciences. vol 232. 2019-09-24. PMID:31226417. |
subsequently, we demonstrated entinostat (hdac1 inhibitor) combination with fludarabine significantly induced apoptosis in tp53 mutations cll cells. |
2019-09-24 |
2023-08-13 |
mouse |
| Zhen Zhou, Qin Fang, Peifan Li, Dan Ma, Nana Zhe, Mei Ren, Bingqing Chen, Zhengchang He, Jun Wang, Qin Zhong, Jishi Wan. Entinostat combined with Fludarabine synergistically enhances the induction of apoptosis in TP53 mutated CLL cells via the HDAC1/HO-1 pathway. Life sciences. vol 232. 2019-09-24. PMID:31226417. |
more importantly, we also confirmed that upregulation of hdac1 could resistant entinostat-induced apoptosis in tp53 mutations cll cells by activating the hdac1/p38/ho-1 pathway. |
2019-09-24 |
2023-08-13 |
mouse |
| Huayi Li, Xingwen Wang, Cheng Zhang, Yiwei Cheng, Miao Yu, Kunming Zhao, Wenjie Ge, Anyong Cai, Yao Zhang, Fengtong Han, Ying H. HDAC1-induced epigenetic silencing of ASPP2 promotes cell motility, tumour growth and drug resistance in renal cell carcinoma. Cancer letters. vol 432. 2019-09-03. PMID:29890207. |
of particular importance, hdac1 inhibitor vorinostat restored aspp2 transcription and produced a synergistic effect with 5-fu in elevating aspp2, promoting apoptosis and inhibiting emt in both in vitro and in vivo rcc models. |
2019-09-03 |
2023-08-13 |
Not clear |
| Shu-Huey Chen, Jyh-Ming Chow, Yao-Yu Hsieh, Chun-Yu Lin, Kai-Wen Hsu, Wen-Shyang Hsieh, Wei-Ming Chi, Beished M Shabangu, Chia-Hwa Le. HDAC1,2 Knock-Out and HDACi Induced Cell Apoptosis in Imatinib-Resistant K562 Cells. International journal of molecular sciences. vol 20. issue 9. 2019-08-30. PMID:31071955. |
using crispr/cas9 genomic editing, we found that hdac1 and hdac2 knockout cells significantly induced cell apoptosis, indicating that the regulation of hdac1 and hdac2 is extremely important in maintaining k562 cell survival. |
2019-08-30 |
2023-08-13 |
Not clear |
| Chao Wen, Yuan-Kang Xie, Yi-Jian Che. [Efflect of miR-34a-Tangeted Regulation of HDACI on Apoptosis of AML Cells]. Zhongguo shi yan xue ye xue za zhi. vol 27. issue 3. 2019-07-11. PMID:31204933. |
to investigate the regulation of mir-34a on hdac1 expression and its effect on the apoptosis of acute myeloid leukemia (aml) cells. |
2019-07-11 |
2023-08-13 |
Not clear |