| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| . Statement of Retraction. Kathrin Maedler, Desiree M. Schumann, Fabienne Schulthess, José Oberholzer, Domenico Bosco, Thierry Berney, and Marc Y. Donath. Aging Correlates With Decreased β-Cell Proliferative Capacity and Enhanced Sensitivity to Apoptosis: A Potential Role for Fas and Pancreatic Duodenal Homeobox-1. Diabetes 2006;55:2455-2462. DOI: 10.2337/db05-1586. PMID: 16936193. Diabetes. vol 69. issue 3. 2020-03-18. PMID:31932299. |
aging correlates with decreased β-cell proliferative capacity and enhanced sensitivity to apoptosis: a potential role for fas and pancreatic duodenal homeobox-1. |
2020-03-18 |
2023-08-13 |
Not clear |
| Michael Skoumal, Kyle B Woodward, Hong Zhao, Feng Wang, Esma S Yolcu, Ryan M Pearson, Kevin R Hughes, Andrés J García, Lonnie D Shea, Haval Shirwa. Localized immune tolerance from FasL-functionalized PLG scaffolds. Biomaterials. vol 192. 2020-03-11. PMID:30458362. |
biotinylated particles and scaffolds efficiently bound sa-fasl and induced apoptosis in cells expressing fas receptor (fasr). |
2020-03-11 |
2023-08-13 |
Not clear |
| Parvaneh Mehrbod, Sudharsana R Ande, Javad Alizadeh, Shahrzad Rahimizadeh, Aryana Shariati, Hadis Malek, Mohammad Hashemi, Kathleen K M Glover, Affan A Sher, Kevin M Coombs, Saeid Ghavam. The roles of apoptosis, autophagy and unfolded protein response in arbovirus, influenza virus, and HIV infections. Virulence. vol 10. issue 1. 2020-03-05. PMID:30966844. |
abbreviation: aids: acquired immunodeficiency syndrome; atf6: activating transcription factor 6; atg6: autophagy-specific gene 6; bag3: bcl associated athanogene 3; bak: bcl-2-anatagonist/killer1; bax; bcl-2: associated x protein; bcl-2: b cell lymphoma 2x; bip: chaperon immunoglobulin heavy chain binding protein; card: caspase recruitment domain; cart: combination antiretroviral therapy; ccr5: c-c chemokine receptor type 5; cd4: cluster of differentiation 4; chop: c/ebp homologous protein; cxcr4: c-x-c chemokine receptor type 4; cyto c: cytochrome c; dcs: dendritic cells; edem1: er-degradation enhancing-a-mannosidase-like protein 1; env: envelope; er: endoplasmic reticulum; fasr: fas receptor;g2: gap 2; g2/m: gap2/mitosis; gfap: glial fibrillary acidic protein; gp120: glycoprotein120; gp41: glycoprotein41; hand: hiv associated neurodegenerative disease; hek: human embryonic kidney; hela: human cervical epithelial carcinoma; hiv: human immunodeficiency virus; ips-1: ifn-β promoter stimulator 1; ire-1: inositol requiring enzyme 1; irgm: immunity related gtpase family m protein; lamp2a: lysosome associated membrane protein 2a; lc3: microtubule associated light chain 3; mda5: melanoma differentiation associated gene 5; mef: mouse embryonic fibroblast; mmp: mitochondrial membrane permeabilization; nef: negative regulatory factor; oasis: old astrocyte specifically induced substrate; pamp: pathogen-associated molecular pattern; perk: pancreatic endoplasmic reticulum kinase; prr: pattern recognition receptor; puma: p53 upregulated modulator of apoptosis; rig-i: retinoic acid-inducible gene-i; tat: transactivator protein of hiv; tlr: toll-like receptor; ulk1: unc51 like autophagy activating kinase 1; upr: unfolded protein response; vpr: viral protein regulatory; xbp1: x-box binding protein 1. |
2020-03-05 |
2023-08-13 |
mouse |
| Tori N Yamamoto, Ping-Hsien Lee, Suman K Vodnala, Devikala Gurusamy, Rigel J Kishton, Zhiya Yu, Arash Eidizadeh, Robert Eil, Jessica Fioravanti, Luca Gattinoni, James N Kochenderfer, Terry J Fry, Bulent Arman Aksoy, Jeffrey E Hammerbacher, Anthony C Cruz, Richard M Siegel, Nicholas P Restifo, Christopher A Klebanof. T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy. The Journal of clinical investigation. vol 129. issue 4. 2020-02-25. PMID:30694219. |
we discovered that genetic engineering of fas variants impaired in the ability to bind fadd functioned as dominant negative receptors (dnrs), preventing fasl-induced apoptosis in fas-competent t cells. |
2020-02-25 |
2023-08-13 |
human |
| Amy E Rumora, Giovanni LoGrasso, Julia A Haidar, Justin J Dolkowski, Stephen I Lentz, Eva L Feldma. Chain length of saturated fatty acids regulates mitochondrial trafficking and function in sensory neurons. Journal of lipid research. vol 60. issue 1. 2020-02-10. PMID:30442656. |
because long-chain saturated fas (sfas) damage drg neurons and medium-chain sfas are reported to improve neuronal function, we evaluated the impact of sfa chain length on mitochondrial trafficking, mitochondrial function, and apoptosis. |
2020-02-10 |
2023-08-13 |
Not clear |
| Jingyi Xue, Xinxin Yan, Yutong Yang, Min Chen, Lulin Wu, Zhongshan Gou, Zhipeng Sun, Shaletanati Talabieke, Yuanyuan Zheng, Dali Lu. Connexin 43 dephosphorylation contributes to arrhythmias and cardiomyocyte apoptosis in ischemia/reperfusion hearts. Basic research in cardiology. vol 114. issue 5. 2020-02-10. PMID:31463533. |
i/r rats had ventricular arrhythmias and myocardial apoptosis with activation of the p38 mitogen-activated protein kinase (p38)/factor-associated suicide (fas)/fas-associating protein with a novel death domain (fadd) pathway. |
2020-02-10 |
2023-08-13 |
rat |
| Xiangnan Guo, Xiaoyan Fu, Xiaona Liu, Jingqiu Wang, Zhongzhe Li, Lin Gao, Yuanyuan Li, Wei Zhan. Role of Pigment Epithelium-Derived Factor in Arsenic-Induced Vascular Endothelial Dysfunction in a Rat Model. Biological trace element research. vol 190. issue 2. 2020-02-04. PMID:30392020. |
the oxidative stress level and key proteins associated with apoptosis such as fas, fasl, p53, and p-p38 were then detected to explore the detailed mechanisms. |
2020-02-04 |
2023-08-13 |
rat |
| Benjamin O Tschumi, Nina Dumauthioz, Bastien Marti, Lianjun Zhang, Evripidis Lanitis, Melita Irving, Pascal Schneider, Jean-Pierre Mach, George Coukos, Pedro Romero, Alena Dond. CART cells are prone to Fas- and DR5-mediated cell death. Journal for immunotherapy of cancer. vol 6. issue 1. 2020-01-31. PMID:30005714. |
importantly, the dominant role of the fas and dr5 pathways in cart cell apoptosis is demonstrated by the significant rescue of cart cells upon in vivo blockade by combined fas-fc and dr5-fc recombinant proteins. |
2020-01-31 |
2023-08-13 |
Not clear |
| Wei Xiao, Mohammed L Ibrahim, Priscilla S Redd, John D Klement, Chunwan Lu, Dafeng Yang, Natasha M Savage, Kebin Li. Loss of Fas Expression and Function Is Coupled with Colon Cancer Resistance to Immune Checkpoint Inhibitor Immunotherapy. Molecular cancer research : MCR. vol 17. issue 2. 2020-01-27. PMID:30429213. |
cancer stem cells are often associated with resistance to therapy including immunotherapy, but the functions of fas in colon cancer apoptosis and colon cancer stem cells are currently conflicting and highly debated. |
2020-01-27 |
2023-08-13 |
human |
| . Expression of Concern. Kathrin Maedler, Desiree M. Schumann, Fabienne Schulthess, José Oberholzer, Domenico Bosco, Thierry Berney, and Marc Y. Donath. Aging Correlates With Decreased β-Cell Proliferative Capacity and Enhanced Sensitivity to Apoptosis: A Potential Role for Fas and Pancreatic Duodenal Homeobox-1. Diabetes 2006;55:2455-2462. DOI: 10.2337/db05-1586. PMID: 16936193. Diabetes. vol 67. issue 11. 2020-01-23. PMID:30213821. |
aging correlates with decreased β-cell proliferative capacity and enhanced sensitivity to apoptosis: a potential role for fas and pancreatic duodenal homeobox-1. |
2020-01-23 |
2023-08-13 |
Not clear |
| Hsin-Ling Yang, Ruei-Wan Lin, Peramaiyan Rajendran, Dony Chacko Mathew, Varadharajan Thigarajan, Chuan-Chen Lee, Chih-Jung Hsu, You-Cheng Hse. Antrodia salmonea-induced oxidative stress abrogates HER-2 signaling cascade and enhanced apoptosis in ovarian carcinoma cells. Journal of cellular physiology. vol 234. issue 3. 2020-01-20. PMID:30146791. |
notably, treatment with a. salmonea induced the following events: apoptosis; caspase-3, -8, -9 and poly(adp-ribose) polymerase activation; first apoptosis signal (fas) and fas ligand activation; bid cleavage; and bax2-b-cell lymphoma 2 dysregulation. |
2020-01-20 |
2023-08-13 |
human |
| Xin Zhang, Jin-Xiu Zhu, Zhen-Guo Ma, Hai-Ming Wu, Si-Chi Xu, Peng Song, Chun-Yan Kong, Yu-Pei Yuan, Wei Deng, Qi-Zhu Tan. Rosmarinic acid alleviates cardiomyocyte apoptosis via cardiac fibroblast in doxorubicin-induced cardiotoxicity. International journal of biological sciences. vol 15. issue 3. 2020-01-20. PMID:30745842. |
mechanistically, cfs-derived fas l was responsible for dox-induced cardiomyocyte apoptosis, and ra treatment could decrease fas l expression in cfs and its release to the conditioned medium by suppressing nuclear factor of activated t cells (nfat) activation and metalloproteinase 7 (mmp7) expression, and exerted the anti-apoptotic effect on cms via cfs. |
2020-01-20 |
2023-08-13 |
mouse |
| Xin Zhang, Jin-Xiu Zhu, Zhen-Guo Ma, Hai-Ming Wu, Si-Chi Xu, Peng Song, Chun-Yan Kong, Yu-Pei Yuan, Wei Deng, Qi-Zhu Tan. Rosmarinic acid alleviates cardiomyocyte apoptosis via cardiac fibroblast in doxorubicin-induced cardiotoxicity. International journal of biological sciences. vol 15. issue 3. 2020-01-20. PMID:30745842. |
in summary, ra alleviated cardiomyocyte apoptosis by inhibiting the expression and release of fas l in cfs via a paracrine manner, moreover, nfat as well as mmp7 inhibition were responsible for the suppression of fas l. ra could be a powerful new therapeutic agent to mitigate cardiomyocyte apoptosis, thereby improving dox-induced cardiotoxicity. |
2020-01-20 |
2023-08-13 |
mouse |
| Tae-Hwan Kim, Hyun-Cheol Lee, Jae-Hoon Kim, C Y Hewawaduge, Kiramage Chathuranga, W A Gayan Chathuranga, Pathum Ekanayaka, H M S M Wijerathne, Chul-Joong Kim, Eunhee Kim, Jong-Soo Le. Fas-associated factor 1 mediates NADPH oxidase-induced reactive oxygen species production and proinflammatory responses in macrophages against Listeria infection. PLoS pathogens. vol 15. issue 8. 2020-01-15. PMID:31412082. |
fas-associated factor 1 is a death-promoting protein that induces apoptosis by interacting with the fas receptor. |
2020-01-15 |
2023-08-13 |
mouse |
| Carmen Sarasquete, María Úbeda-Manzanaro, Juan B Ortiz-Delgad. Effects of the isoflavone daidzein in Senegalese sole, Solea senegalensis: Modulation of the oestrogen receptor-β, apoptosis and enzymatic signalling pathways. Histology and histopathology. vol 34. issue 8. 2020-01-14. PMID:30729492. |
in general, the oestrogen receptor (erβ) and stimulating apoptosis death receptor factor (fas) transcript levels showed similar baseline patterns and transcriptional responses induced by daidzein. |
2020-01-14 |
2023-08-13 |
Not clear |
| Yanglei Li, Fang Shen, Yiqi Bao, Dongming Chen, Hong L. Apoptotic effects of rhein through the mitochondrial pathways, two death receptor pathways, and reducing autophagy in human liver L02 cells. Environmental toxicology. vol 34. issue 12. 2020-01-14. PMID:31436023. |
the results of our studies indicated that rhein induced caspase-dependent apoptosis via both the fas death pathway and the mitochondrial pathway by generating ros, and meanwhile the autophagy tended to weaken. |
2020-01-14 |
2023-08-13 |
human |
| Rui Liu, Yajuan Chen, Tao Shou, Jing Hu, Jingbo Chen, Chen Qin. TRIM67 promotes NF‑κB pathway and cell apoptosis in GA‑13315‑treated lung cancer cells. Molecular medicine reports. vol 20. issue 3. 2020-01-13. PMID:31322254. |
ga‑13315 promoted trim67 expression to increase fas expression and cell apoptosis. |
2020-01-13 |
2023-08-13 |
human |
| Ankur Datta, Saibal Moitra, Sk Md Omar Faruk, Prasanta K Das, Somnath Mondal, Iman Hazra, Anjan K Basu, Santanu K Tripathi, Swapna Chaudhur. Unravelling the apoptotic mechanisms in T-lymphocytes in an animal model for pollen induced airway allergy and studying the impact of specific immunotherapy. Immunobiology. vol 224. issue 2. 2020-01-09. PMID:30471949. |
the study demonstrates that allergen sensitization and challenge reduced apoptosis of splenic t-lymphocytes via fas mediated extrinsic pathway, bax/bcl2 regulated intrinsic pathway and also perforin/granzyme mediated pathway which were normalized following allergen specific intranasal immunotherapy. |
2020-01-09 |
2023-08-13 |
rat |
| Ae Ra Han, Young Min Choi, Min A Hong, Jin Ju Kim, Sung Ki Lee, Kwang Moon Yang, Eun Chan Paik, Hyeon Jeong Jeong, Jong Kwan Ju. Fas and FasL genetic polymorphisms in women with recurrent pregnancy loss: a case-control study. Human fertility (Cambridge, England). vol 22. issue 3. 2020-01-08. PMID:29781316. |
aberrant apoptosis at the trophoblast-maternal interface and abnormal expression of fas and fas ligand (fasl) have been reported in complicated pregnancies with recurrent pregnancy losses (rpl) and preeclampsia. |
2020-01-08 |
2023-08-13 |
Not clear |
| Yulong Cai, Yixin Lin, Xianze Xiong, Jiong Lu, Rongxing Zhou, Yanwen Jin, Zhen You, Hui Ye, Fuyu Li, Nansheng Chen. Knockdown expression of MECR, a novel gene of mitochondrial FAS II inhibits growth and colony-formation, promotes apoptosis of hepatocelluar carcinoma cells. Bioscience trends. vol 13. issue 3. 2019-12-30. PMID:31178528. |
knockdown expression of mecr, a novel gene of mitochondrial fas ii inhibits growth and colony-formation, promotes apoptosis of hepatocelluar carcinoma cells. |
2019-12-30 |
2023-08-13 |
Not clear |