| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Neetu Singh, Mohammad Shafiq, Kumaravelu Jagavelu, Kashif Hani. Involvement of fatty acid synthase in right ventricle dysfunction in pulmonary hypertension. Experimental cell research. vol 383. issue 2. 2020-06-29. PMID:31465767. |
sirna mediated inhibition of fas reduced fas expression, hypertrophy, inflammation, apoptosis, autophagy and improved the glucose oxidation, mitochondrial membrane potential and atp level in hypoxic cardiomyocytes. |
2020-06-29 |
2023-08-13 |
rat |
| Ruiyin Wang, Jiangtao Lin, Jingru Wang, Chunxiao L. [Effects of artesunate on eosinophil apoptosis and expressions of Fas and Bcl-2 proteins in asthmatic mice]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 40. issue 1. 2020-06-29. PMID:32376556. |
[effects of artesunate on eosinophil apoptosis and expressions of fas and bcl-2 proteins in asthmatic mice]. |
2020-06-29 |
2023-08-13 |
mouse |
| Ruiyin Wang, Jiangtao Lin, Jingru Wang, Chunxiao L. [Effects of artesunate on eosinophil apoptosis and expressions of Fas and Bcl-2 proteins in asthmatic mice]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 40. issue 1. 2020-06-29. PMID:32376556. |
to observe the effects of artesunate on eosinophil (eos) apoptosis and fas and bcl-2 protein expressions in asthmatic mice. |
2020-06-29 |
2023-08-13 |
mouse |
| Brunno Felipe Ramos Caetano, Mariana Baptista Tablas, Guilherme Ribeiro Romualdo, Maria Aparecida Marchesan Rodrigues, Luís Fernando Barbisa. Early molecular events associated with liver and colon sub-acute responses to 1,2-dimethylhydrazine: Potential implications on preneoplastic and neoplastic lesion development. Toxicology letters. vol 329. 2020-06-15. PMID:32387197. |
apoptosis effectors were upregulated in the liver (bax, casp3 and fas), and developmental genes were downregulated in both colon and liver (foxa1, foxa2, smad2 and smad4). |
2020-06-15 |
2023-08-13 |
rat |
| Inga Peciuliene, Laurynas Vilys, Egle Jakubauskiene, Lolita Zaliauskiene, Arvydas Kanopk. Hypoxia alters splicing of the cancer associated Fas gene. Experimental cell research. vol 380. issue 1. 2020-06-08. PMID:31002816. |
fas pre-mrna is alternatively spliced by excluding exon 6 to produce soluble fas (sfas) protein that lacks a transmembrane domain and acts by inhibiting fas mediated apoptosis. |
2020-06-08 |
2023-08-13 |
Not clear |
| Seokhwi Kim, Nury Kim, Jinsu Lee, Sungsoo Kim, Jongryul Hong, Seungkyu Son, Won Do He. Dynamic Fas signaling network regulates neural stem cell proliferation and memory enhancement. Science advances. vol 6. issue 17. 2020-06-06. PMID:32494656. |
activation of fas (cd95) is observed in various neurological disorders and can lead to both apoptosis and prosurvival outputs, yet how fas signaling operates dynamically in the hippocampus is poorly understood. |
2020-06-06 |
2023-08-13 |
mouse |
| Francisco Javier Cubero, Marius Maximilian Woitok, Miguel E Zoubek, Alain de Bruin, Maximilian Hatting, Christian Trautwei. Disruption of the FasL/Fas axis protects against inflammation-derived tumorigenesis in chronic liver disease. Cell death & disease. vol 10. issue 2. 2020-06-04. PMID:30737368. |
fas ligand (fasl) and fas (apo-1/cd95) are members of the tnfr superfamily and may trigger apoptosis. |
2020-06-04 |
2023-08-13 |
Not clear |
| Yan-Ping Zhang, Kai-Long Liu, Ya-Xuan Wang, Zhan Yang, Zhen-Wei Han, Bao-Sai Lu, Jin-Chun Qi, Yue-Wei Yin, Zhi-Hai Teng, Xue-Liang Chang, Jing-Dong Li, Hong Xin, Wei L. Down-regulated RBM5 inhibits bladder cancer cell apoptosis by initiating an miR-432-5p/β-catenin feedback loop. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 33. issue 10. 2020-06-01. PMID:31318608. |
rna-binding motif protein 5 (rbm5) acts as a tumor suppressor in various human cancers and presents with several important characteristics, such as the potentiation of apoptosis, inhibition of the cell cycle, and alternative splicing of fas and caspase-2 precursor mrna. |
2020-06-01 |
2023-08-13 |
human |
| Daniel R Matson, David T Yan. Autoimmune Lymphoproliferative Syndrome: An Overview. Archives of pathology & laboratory medicine. vol 144. issue 2. 2020-05-12. PMID:30958694. |
autoimmune lymphoproliferative syndrome (alps) is an inherited nonmalignant lymphoproliferative disorder characterized by heterozygous mutations within the first apoptosis signal receptor (fas) signaling pathway. |
2020-05-12 |
2023-08-13 |
Not clear |
| Yuan Zhang, Ji Zhou, Ming-Qing Li, Jie Xu, Jin-Ping Zhang, Li-Ping Ji. MicroRNA-184 promotes apoptosis of trophoblast cells via targeting WIG1 and induces early spontaneous abortion. Cell death & disease. vol 10. issue 3. 2020-05-06. PMID:30833572. |
further exploration indicated that mir-184 upregulated the expression of fas by targeting wig1 thus inducing cell apoptosis. |
2020-05-06 |
2023-08-13 |
mouse |
| Isabel Prager, Carsten Watz. Mechanisms of natural killer cell-mediated cellular cytotoxicity. Journal of leukocyte biology. vol 105. issue 6. 2020-05-04. PMID:31107565. |
nk cells can kill virally infected of transformed cells via the directed release of lytic granules or by inducing death receptor-mediated apoptosis via the expression of fas ligand or trail. |
2020-05-04 |
2023-08-13 |
Not clear |
| Huijie Chen, Rui Feng, Ishfaq Muhammad, Ghulam Abbas, Yue Zhang, Yudong Ren, Xiaodan Huang, Ruili Zhang, Lei Diao, Xiurong Wang, Guangxing L. Protective effects of hypericin against infectious bronchitis virus induced apoptosis and reactive oxygen species in chicken embryo kidney cells. Poultry science. vol 98. issue 12. 2020-04-28. PMID:31399732. |
furthermore, hy inhibited ibv-induced apoptosis in cek cells, and significantly reduced the mrna expression levels of fas, fasl, jnk, bax, caspase 3, and caspase 8, and significantly increased bcl-2 mrna expression level in cek cells. |
2020-04-28 |
2023-08-13 |
chicken |
| Asadollah Mohammadi, Maryam Salehi, Hashem Khanbabaei, Farshad Sheikhesmaeili, Nader Tajik, Seyed Moayed Alavia. Fas and FasL promoter polymorphisms and susceptibility to HBV infection: A systematic review and meta-analysis. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. vol 76. 2020-04-24. PMID:31425784. |
fas and fasl system act as a major death pathway that triggers apoptosis cascade in the liver. |
2020-04-24 |
2023-08-13 |
Not clear |
| Outi Mantere, Kalevi Trontti, Judit García-González, Ingrid Balcells, Suvi Saarnio, Teemu Mäntylä, Maija Lindgren, Tuula Kieseppä, Tuukka Raij, Jarno K Honkanen, Outi Vaarala, Iiris Hovatta, Jaana Suvisaar. Immunomodulatory effects of antipsychotic treatment on gene expression in first-episode psychosis. Journal of psychiatric research. vol 109. 2020-03-27. PMID:30463035. |
of the individual medications used as monotherapy, risperidone was associated with a statistically significant upregulation of 11 immune system genes, including cytokines and cytokine receptors (spp1, il1r1, il1r2), pattern recognition molecules (tlr1, tlr2 and tlr6, dectin-1/clec7a), molecules involved in apoptosis (fas), and some other molecules with functions in immune activation (bdkrb1, igf1r, cr1). |
2020-03-27 |
2023-08-13 |
Not clear |
| Jun Xia, Weihui Zeng, Yumin Xia, Bingchuan Wang, Dehui Xu, Dingxin Liu, Michael G Kong, Yingying Don. Cold atmospheric plasma induces apoptosis of melanoma cells via Sestrin2-mediated nitric oxide synthase signaling. Journal of biophotonics. vol 12. issue 1. 2020-03-25. PMID:29931745. |
here, we identified the tumor necrosis factor-family members, especially fas, and overloaded intracellular nitric oxide participated in cap induced apoptosis in a375 and a875 melanoma cell lines, which was known as extrinsic apoptosis pathway. |
2020-03-25 |
2023-08-13 |
Not clear |
| Jun Xia, Weihui Zeng, Yumin Xia, Bingchuan Wang, Dehui Xu, Dingxin Liu, Michael G Kong, Yingying Don. Cold atmospheric plasma induces apoptosis of melanoma cells via Sestrin2-mediated nitric oxide synthase signaling. Journal of biophotonics. vol 12. issue 1. 2020-03-25. PMID:29931745. |
depletion of sestrin2 reduced inos and fas expression, which was associated with reduction of plasma-induced apoptosis. |
2020-03-25 |
2023-08-13 |
Not clear |
| Jun Xia, Weihui Zeng, Yumin Xia, Bingchuan Wang, Dehui Xu, Dingxin Liu, Michael G Kong, Yingying Don. Cold atmospheric plasma induces apoptosis of melanoma cells via Sestrin2-mediated nitric oxide synthase signaling. Journal of biophotonics. vol 12. issue 1. 2020-03-25. PMID:29931745. |
taken together, cold atmospheric plasma increases sestrin2 expression and further activates downstream inos, fas and p38 mapk signaling to induce apoptosis of melanoma cell lines. |
2020-03-25 |
2023-08-13 |
Not clear |
| Danyang Li, Pengyan Song, Liantao Liu, Xiaodan Wan. Perfluorooctanoic acid exposure during pregnancy alters the apoptosis of uterine cells in pregnant mice. International journal of clinical and experimental pathology. vol 11. issue 12. 2020-03-25. PMID:31949647. |
the results indicated that pfoa could accelerate the apoptosis of uterine cells, and lead to slow embryo development or abortion by regulating the expression of fas, fasl, bax, bcl-2 and caspase-3 in uterine cells. |
2020-03-25 |
2023-08-13 |
mouse |
| Young Min Kwon, Jae-Young Je, Seung Heon Cha, Yunok Oh, Won Ho Ch. Synergistic combination of chemo‑phototherapy based on temozolomide/ICG‑loaded iron oxide nanoparticles for brain cancer treatment. Oncology reports. vol 42. issue 5. 2020-03-23. PMID:31436296. |
western blot analysis and reverse transcription‑quantitative polymerase chain reaction revealed that fe3o4‑tmz‑icg mnps with nir laser irradiation lead to significantly enhanced anticancer effects on u‑87 mg glioblastoma cells through the modulation of intrinsic and extrinsic apoptosis genes, including bcl‑2‑associated x protein, bcl‑2, cytochrome c, caspase‑3, fas associated via death domain and caspase‑8. |
2020-03-23 |
2023-08-13 |
human |
| Anitha Krishnan, Andrew J Kocab, David N Zacks, Ann Marshak-Rothstein, Meredith Gregory-Ksande. A small peptide antagonist of the Fas receptor inhibits neuroinflammation and prevents axon degeneration and retinal ganglion cell death in an inducible mouse model of glaucoma. Journal of neuroinflammation. vol 16. issue 1. 2020-03-23. PMID:31570110. |
we demonstrated previously that fasl-fas signaling was required for axon degeneration and death of rgcs in chronic and inducible mouse models of glaucoma and that fas activation triggered rgc apoptosis, glial activation, and inflammation. |
2020-03-23 |
2023-08-13 |
mouse |