| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhao Luo, Zhen Zhang, Fuyu Zhang, Ying Liu, Yang Zhang, Xiaodong Sun, Ming Sang, Huiyu Lu. Ropivacaine mesylate exerts neurotoxicity via up-regulation of Fas/FasL expression in rat pheochromocytoma PC12 cells. American journal of translational research. vol 11. issue 3. 2020-09-30. PMID:30972188. |
then, cells in 0.5 mmol/l ropivacaine group, 2 mmol/l ropivacaine group and control group were subjected to morphological observation under a light microscope, assessment of cell necrosis by hoechst33342/pi staining and apoptosis by annexin v-fitc/pi staining, and the detection of fas and fasl expression by qpcr, immunofluorescence and western blot. |
2020-09-30 |
2023-08-13 |
rat |
| Aurélie Rossin, Giorgia Miloro, Anne-Odile Huebe. TRAIL and FasL Functions in Cancer and Autoimmune Diseases: Towards an Increasing Complexity. Cancers. vol 11. issue 5. 2020-09-30. PMID:31072029. |
tumor necrosis factor-related apoptosis inducing ligand (trail/tnfsf10) and fas ligand (fasl/tnfsf6), two major cytokines of the tnf (tumor necrosis factor) superfamily, exert their main functions from the immune system compartment. |
2020-09-30 |
2023-08-13 |
mouse |
| Wenyuan Huang, Yan Liang, Xiaofeng M. Alpha-mangostin induces endoplasmic reticulum stress and autophagy which count against fatty acid synthase inhibition mediated apoptosis in human breast cancer cells. Cancer cell international. vol 19. 2020-09-30. PMID:31164796. |
however, the role of er stress and autophagy in fas inhibition induced apoptosis still remains unclear. |
2020-09-30 |
2023-08-13 |
human |
| Z-Ju Qu, Z-Ji Qu, H-B Zhou, C-S Xu, D-Z Zhang, G Wan. Protective effect of remifentanil on myocardial ischemia-reperfusion injury through Fas apoptosis signaling pathway. European review for medical and pharmacological sciences. vol 23. issue 13. 2020-09-30. PMID:31298349. |
protective effect of remifentanil on myocardial ischemia-reperfusion injury through fas apoptosis signaling pathway. |
2020-09-30 |
2023-08-13 |
Not clear |
| Z-Ju Qu, Z-Ji Qu, H-B Zhou, C-S Xu, D-Z Zhang, G Wan. Protective effect of remifentanil on myocardial ischemia-reperfusion injury through Fas apoptosis signaling pathway. European review for medical and pharmacological sciences. vol 23. issue 13. 2020-09-30. PMID:31298349. |
the aim of this study was to investigate the protective effect of remifentanil (rft) on myocardial ischemia-reperfusion (ir) injury through fas apoptosis signaling pathway. |
2020-09-30 |
2023-08-13 |
Not clear |
| Qin Ye, Yu-Ni Lin, Mao-Song Xie, Yi-Hua Yao, Shu-Min Tang, Yan Huang, Xiao-Hui Wang, Yi-Hua Zh. Effects of etanercept on the apoptosis of ganglion cells and expression of Fas, TNF-α, caspase-8 in the retina of diabetic rats. International journal of ophthalmology. vol 12. issue 7. 2020-09-30. PMID:31341796. |
effects of etanercept on the apoptosis of ganglion cells and expression of fas, tnf-α, caspase-8 in the retina of diabetic rats. |
2020-09-30 |
2023-08-13 |
rat |
| Shengli Xu, Jianxin Huo, Yuhan Huang, Melissa Aw, Shuwen Chen, Shiya Mak, Lian Yee Yip, Ying Swan Ho, Sze Wai Ng, Andy Hee-Meng Tan, Alison Lee, Xijun Ou, Kong-Peng La. von Hippel-Lindau Protein Maintains Metabolic Balance to Regulate the Survival of Naive B Lymphocytes. iScience. vol 17. 2020-09-30. PMID:31351078. |
mechanistically, the metabolic imbalance in vhl-deficient b cells, arising from over-stabilization of hypoxia-inducible factor-1α (hif-1α), triggers reductive glutamine metabolism leading to increased fas palmitoylation and caspase-8-mediated apoptosis. |
2020-09-30 |
2023-08-13 |
Not clear |
| Katharina Beyer, Ann-Kathrin Baukloh, Ani Stoyanova, Carsten Kamphues, Arne Sattler, Katja Kotsc. Interactions of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) with the Immune System: Implications for Inflammation and Cancer. Cancers. vol 11. issue 8. 2020-09-30. PMID:31412671. |
trail has historically been distinct from the fas ligand and tnfα in terms of selective apoptosis induction in tumor cells and has a nearly non-existent systemic toxicity. |
2020-09-30 |
2023-08-13 |
Not clear |
| Ko-Chao Lee, Kam-Fai Lee, Shui-Yi Tung, Wen-Shih Huang, Li-Ya Lee, Wan-Ping Chen, Chin-Chu Chen, Chih-Chuan Teng, Chien-Heng Shen, Meng-Chiao Hsieh, Hsing-Chun Ku. Induction Apoptosis of Erinacine A in Human Colorectal Cancer Cells Involving the Expression of TNFR, Fas, and Fas Ligand Frontiers in pharmacology. vol 10. 2020-09-30. PMID:31680958. |
induction apoptosis of erinacine a in human colorectal cancer cells involving the expression of tnfr, fas, and fas ligand erinacine a, which is one of the major bioactive diterpenoid compounds extracted from cultured mycelia of |
2020-09-30 |
2023-08-13 |
human |
| Jinyu Li, Xiaoying Meng, Changzhi Wang, Huijie Zhang, Hening Chen, Peiying Deng, Juan Liu, Meiyier Huandike, Jie Wei, Limin Cha. Coptidis alkaloids extracted from Coptis chinensis Franch attenuate IFN-γ-induced destruction of bone marrow cells. PloS one. vol 15. issue 7. 2020-09-30. PMID:32706801. |
western blotting analysis was used to assay the expression of key molecules in the fas apoptosis and jak/stats signaling pathways in bmcs. |
2020-09-30 |
2023-08-13 |
mouse |
| Jinyu Li, Xiaoying Meng, Changzhi Wang, Huijie Zhang, Hening Chen, Peiying Deng, Juan Liu, Meiyier Huandike, Jie Wei, Limin Cha. Coptidis alkaloids extracted from Coptis chinensis Franch attenuate IFN-γ-induced destruction of bone marrow cells. PloS one. vol 15. issue 7. 2020-09-30. PMID:32706801. |
the levels of key molecules (fas, caspase-3, cleaved caspase-3, caspase-8 and caspase-8) in fas apoptosis signaling pathways also decreased significantly after treatment with low concentrations of coptidis alkaloids. |
2020-09-30 |
2023-08-13 |
mouse |
| Kazuo Yoneyama, Takashi Goto, Kouichi Miura, Ken ichirou Mikami, Shigetoshi Ohshima, Kunio Nakane, Jiun Guey Lin, Masashiro Sugawara, Norio Nakamura, Kamon Shirakawa, Masafumi Komatsu, Sumio Watanab. The expression of Fas and Fas ligand, and the effects of interferon in chronic liver diseases with hepatitis C virus. Hepatology research : the official journal of the Japan Society of Hepatology. vol 24. issue 4. 2020-09-29. PMID:12479930. |
in viral hepatitis, binding of fas ligand (fasl) with fas expressed on the surfaces of infected hepatocytes induces apoptosis, removing hepatitis virus along with infected hepatocytes. |
2020-09-29 |
2023-08-12 |
human |
| Jeon Hwang-Bo, Jong-Hwa Park, In Sik Chun. Tumstatin induces apoptosis mediated by Fas signaling pathway in oral squamous cell carcinoma SCC-VII cells. Oncology letters. vol 10. issue 2. 2020-09-29. PMID:26622617. |
tumstatin induces apoptosis mediated by fas signaling pathway in oral squamous cell carcinoma scc-vii cells. |
2020-09-29 |
2023-08-13 |
Not clear |
| Jinny Tomar, Chiranjib Chakraborty, C George Priya Doss, V K Ger. Understanding the conservation patterns and molecular phylogenetics of human death receptors family through computational biology. 3 Biotech. vol 4. issue 2. 2020-09-29. PMID:28324447. |
human death receptors (tnfr1, fas, dr3, dr4, dr5, dr6 and tnfbr), primarily from tumor necrosis receptor super family, play an essential role in the process of the extrinsic pathway of apoptosis. |
2020-09-29 |
2023-08-13 |
human |
| Yubin Ji, Miao Yu, Zheng Qi, Di Cui, Guosong Xin, Bing Wang, Weiling Jia, Lin Chan. Study on apoptosis effect of human breast cancer cell MCF-7 induced by lycorine hydrochloride via death receptor pathway. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society. vol 25. issue 4. 2020-09-29. PMID:28579903. |
the results showed that the higher the dose, the higher the rate of apoptosis and that the rate of apoptosis was dependent on the dose; the relative protein activity of fas, fasl, caspase-8 and bid gradually rose with the increase of lycorine dosage and the activities revealed certain dose-independence. |
2020-09-29 |
2023-08-13 |
human |
| Xia Ren, Zhiyong Zhang, Jing Tian, Hengxiao Wang, Guanhua Song, Qiang Guo, Jing Tian, Yang Han, Qiong Liao, Guoqiang Liu, Huifang Ding, Guosheng Jian. The downregulation of c-Myc and its target gene hTERT is associated with the antiproliferative effects of baicalin on HL-60 cells. Oncology letters. vol 14. issue 6. 2020-09-29. PMID:29163703. |
in the present study, the effect of baicalin on the expression of caspase-8, fas cell surface death receptor (fas) and fas ligand in hl-60 cells was assessed, and it was demonstrated that the fas-mediated extrinsic pathway was also involved in baicalin-triggered cell apoptosis, in addition to the intrinsic pathway. |
2020-09-29 |
2023-08-13 |
Not clear |
| Masome Ghasemi-Pirbaluti, Batoul Pourgheysari, Hedayatollah Shirzad, Zahra Sourani, Pezhman Beshka. The Inhibitory Effect of Epigallocatechin Gallate on the Viability of T Lymphoblastic Leukemia Cells is Associated with Increase of Caspase-3 Level and Fas Expression. Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion. vol 34. issue 2. 2020-09-29. PMID:29622866. |
apoptosis and the level of caspase 3 alterations were evaluated using flowcytometry and expression of fas by real time pcr. |
2020-09-29 |
2023-08-13 |
Not clear |
| Nobuhiko Kubo, Sara McCurdy, William A Boisver. Defective Fas Expression on Bone Marrow Derived Cells Alters Atherosclerotic Plaque Morphology in Hyperlipidemic Mice. Discoveries (Craiova, Romania). vol 3. issue 1. 2020-09-28. PMID:26322329. |
interaction of fas with its receptor, fas ligand (fas-l), stimulates an intracellular cascade of events that leads to apoptosis. |
2020-09-28 |
2023-08-13 |
mouse |
| Nobuhiko Kubo, Sara McCurdy, William A Boisver. Defective Fas Expression on Bone Marrow Derived Cells Alters Atherosclerotic Plaque Morphology in Hyperlipidemic Mice. Discoveries (Craiova, Romania). vol 3. issue 1. 2020-09-28. PMID:26322329. |
because apoptosis of inflammatory cells plays a key role in atherosclerosis we sought to determine the role of fas in the development of atherosclerosis by repopulating the bone marrow cells of atherosclerosis-prone low density lipoprotein receptor null (ldl-r-/-) mice with either cells from lpr mice (lpr-bmt) that have defective fas expression or from control mice (wt-bmt). |
2020-09-28 |
2023-08-13 |
mouse |
| Sorah Yoon, Xiwei Wu, Brian Armstrong, Nagy Habib, John J Ross. An RNA Aptamer Targeting the Receptor Tyrosine Kinase PDGFRα Induces Anti-tumor Effects through STAT3 and p53 in Glioblastoma. Molecular therapy. Nucleic acids. vol 14. 2020-09-28. PMID:30594071. |
pdr3 also upregulated serine phosphorylation of p53, which subsequently mediated apoptosis through the death receptors: tumor necrosis factor (tnf)-related apoptosis-inducing ligand receptors 1/2 (trail-r1/r2), fas-associated via death domain (fadd), and fas. |
2020-09-28 |
2023-08-13 |
human |