| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chunwan Lu, John D Klement, Dafeng Yang, Thomas Albers, Iryna O Lebedyeva, Jennifer L Waller, Kebin Li. SUV39H1 regulates human colon carcinoma apoptosis and cell cycle to promote tumor growth. Cancer letters. vol 476. 2020-12-14. PMID:32061753. |
suv39h1-selective inhibitor f5446 decreased h3k9me3 deposition at the fas promoter, increased fas expression, and increased crc cell sensitivity to fasl-induced apoptosis in vitro. |
2020-12-14 |
2023-08-13 |
human |
| Hui Chen, Yongjun Chen, Xin Wang, Jing Yang, Congxin Huan. Edaravone attenuates myocyte apoptosis through the JAK2/STAT3 pathway in acute myocardial infarction. Free radical research. vol 54. issue 5. 2020-12-14. PMID:32543312. |
the mrna levels for bcl-2, bax, fas, and fasl were measured by rt-pcr and apoptosis was assessed by tunel. |
2020-12-14 |
2023-08-13 |
rat |
| Sarah C S V Tanaka, Ivanir C Orlando JÚnior, Andrezza C C Hortolani, MariÂngela T R Cintra, Marly A S Balarin, Sueli R DA Silva, Cristina W Pissett. FAS gene polymorphisms (rs3740286 and rs4064) were not associated with pre-eclampsia risk. Anais da Academia Brasileira de Ciencias. vol 92. issue 4. 2020-12-10. PMID:33295579. |
considering the importance of apoptosis to pre-eclampsia genesis, the aim of this study was to determine the frequencies of the genotypes for fas gene polymorphisms (rs3740286 and rs4064) and to associate these with pre-eclampsia development. |
2020-12-10 |
2023-08-13 |
Not clear |
| b' Fr\\xc3\\xa9d\\xc3\\xa9ric Velard, Aurore Chatron-Colliet, Dominique C\\xc3\\xb4me, Marie-Dominique Ah-Kioon, Hil\\xc3\\xa8ne Lin, Narjes Hafsia, Martine Cohen-Solal, Hang-Korng Ea, Fr\\xc3\\xa9d\\xc3\\xa9ric Liot\\xc3\\xa. Adrenomedullin and truncated peptide adrenomedullin(22-52) affect chondrocyte response to apoptotis in vitro: downregulation of FAS protects chondrocyte from cell death. Scientific reports. vol 10. issue 1. 2020-12-08. PMID:33028903.' |
bovine articular chondrocytes (bacs) were cultured under hypoxic conditions to mimic cartilage environment and then treated with fas ligand (fas-l) to induce apoptosis. |
2020-12-08 |
2023-08-13 |
cattle |
| b' Fr\\xc3\\xa9d\\xc3\\xa9ric Velard, Aurore Chatron-Colliet, Dominique C\\xc3\\xb4me, Marie-Dominique Ah-Kioon, Hil\\xc3\\xa8ne Lin, Narjes Hafsia, Martine Cohen-Solal, Hang-Korng Ea, Fr\\xc3\\xa9d\\xc3\\xa9ric Liot\\xc3\\xa. Adrenomedullin and truncated peptide adrenomedullin(22-52) affect chondrocyte response to apoptotis in vitro: downregulation of FAS protects chondrocyte from cell death. Scientific reports. vol 10. issue 1. 2020-12-08. PMID:33028903.' |
am decreased articular chondrocyte apoptosis by downregulating a fas receptor. |
2020-12-08 |
2023-08-13 |
cattle |
| Chengyi Liu, Meng Qi, Lin Li, Yuan Yuan, Xiaoping Wu, Junsheng F. Natural cordycepin induces apoptosis and suppresses metastasis in breast cancer cells by inhibiting the Hedgehog pathway. Food & function. vol 11. issue 3. 2020-12-04. PMID:32163051. |
cordycepin-induced apoptosis led to increased puma, cyto-c, fas, dr4/5, and cleaved caspase-3; and decreased bcl-2, xiap and pdgfr-α. |
2020-12-04 |
2023-08-13 |
human |
| Aniello Maiese, Alessandra De Matteis, Giorgio Bolino, Emanuela Turillazzi, Paola Frati, Vittorio Finesch. Hypo-Expression of Flice-Inhibitory Protein and Activation of the Caspase-8 Apoptotic Pathways in the Death-Inducing Signaling Complex Due to Ischemia Induced by the Compression of the Asphyxiogenic Tool on the Skin in Hanging Cases. Diagnostics (Basel, Switzerland). vol 10. issue 11. 2020-12-01. PMID:33198065. |
the c-flip plays as an inhibitor of apoptosis induced by a variety of agents, such as tumor necrosis factor (tnf), t cell receptor (tcr), tnf-related apoptosis inducing ligand (trail), fas and death receptor (dr). |
2020-12-01 |
2023-08-13 |
human |
| Mingliang Zhang, Xiao Lin, Jinping Zhang, Lin Su, Mingming Ma, Vicki L Ea, Xun Liu, Liming Wang, Jin Chang, Xiaorong Li, Xiaomin Zhan. Blue light-triggered optogenetic system for treating uveal melanoma. Oncogene. vol 39. issue 10. 2020-11-25. PMID:31811271. |
we found that blue light irradiation dynamically controlled the translocation of fadd to fas on the plasma membrane and induced the apoptosis of b16 cells transfected with the optogenetic nanosystem in vitro. |
2020-11-25 |
2023-08-13 |
Not clear |
| Inés Ruedas-Torres, Irene Magdalena Rodríguez-Gómez, Jose María Sánchez-Carvajal, Francisco José Pallares, Inmaculada Barranco, Librado Carrasco, Jaime Gómez-Lagun. Activation of the extrinsic apoptotic pathway in the thymus of piglets infected with PRRSV-1 strains of different virulence. Veterinary microbiology. vol 243. 2020-11-24. PMID:32273018. |
in both infected groups, there was an increase in the number of cells expressing molecules related to the extrinsic pathway of apoptosis (ccasp8 and fas) in cortex and medulla, showing an important role in the apoptosis induction produced in thymus of prrsv-infected piglets. |
2020-11-24 |
2023-08-13 |
Not clear |
| Ying-Feng Su, Yi-Feng Zang, Yu-Hong Wang, Yin-Lu Din. MiR-19-3p Induces Tumor Cell Apoptosis via Targeting FAS in Rectal Cancer Cells. Technology in cancer research & treatment. vol 19. 2020-11-20. PMID:32266860. |
mir-19-3p induces tumor cell apoptosis via targeting fas in rectal cancer cells. |
2020-11-20 |
2023-08-13 |
Not clear |
| Ying-Feng Su, Yi-Feng Zang, Yu-Hong Wang, Yin-Lu Din. MiR-19-3p Induces Tumor Cell Apoptosis via Targeting FAS in Rectal Cancer Cells. Technology in cancer research & treatment. vol 19. 2020-11-20. PMID:32266860. |
taken together, these results indicated that microrna-19a-3p overexpression inhibited hct116 cell proliferation, migration and invasion, induced cell apoptosis, and ros accumulation via fas targeting effect. |
2020-11-20 |
2023-08-13 |
Not clear |
| Xiangnan Guo, Xiaona Liu, Jingqiu Wang, Xiaoyan Fu, Jinyin Yao, Xiaodan Zhang, Sira Jackson, Jinyu Li, Wei Zhang, Dianjun Su. Pigment epithelium-derived factor (PEDF) ameliorates arsenic-induced vascular endothelial dysfunction in rats and toxicity in endothelial EA.hy926 cells. Environmental research. vol 186. 2020-11-20. PMID:32315827. |
the recovery from arsenite exposure was associated with increased levels of pedf; decreased protein levels of fas, fasl, p53, and phospho-p38; and inhibited apoptosis in aortic endothelial cells in vivo. |
2020-11-20 |
2023-08-13 |
human |
| Chang-Feng Chu, Hsing-Kai Feng, Kuang-Hui Sun, Chia-Lin Hsu, Ivan L Dzhagalo. Examination of Fas-Induced Apoptosis of Murine Thymocytes in Thymic Tissue Slices Reveals That Fas Is Dispensable for Negative Selection. Frontiers in cell and developmental biology. vol 8. 2020-11-17. PMID:33195241. |
examination of fas-induced apoptosis of murine thymocytes in thymic tissue slices reveals that fas is dispensable for negative selection. |
2020-11-17 |
2023-08-13 |
Not clear |
| Chang-Feng Chu, Hsing-Kai Feng, Kuang-Hui Sun, Chia-Lin Hsu, Ivan L Dzhagalo. Examination of Fas-Induced Apoptosis of Murine Thymocytes in Thymic Tissue Slices Reveals That Fas Is Dispensable for Negative Selection. Frontiers in cell and developmental biology. vol 8. 2020-11-17. PMID:33195241. |
the death receptor fas can induce cell death through the extrinsic pathway of apoptosis in a variety of cells, including developing thymocytes. |
2020-11-17 |
2023-08-13 |
Not clear |
| Faizah Alotaibi, Mateusz Rytelewski, Rene Figueredo, Ronak Zareardalan, Meng Zhang, Peter J Ferguson, Saman Maleki Vareki, Yousef Najajreh, Mikal El-Hajjar, Xiufen Zheng, Wei-Ping Min, James Koropatnic. CD5 blockade enhances ex vivo CD8 European journal of immunology. vol 50. issue 5. 2020-10-28. PMID:31943150. |
furthermore, it enhanced tcr signalling (erk activation) and increased markers of t cell activation, including proliferation, cd69 levels, ifn-γ production, apoptosis and fas receptor and fas ligand levels. |
2020-10-28 |
2023-08-13 |
mouse |
| Ki-Tae Jung, Seon-Hee O. Polyubiquitination of p62/SQSTM1 is a prerequisite for Fas/CD95 aggregation to promote caspase-dependent apoptosis in cadmium-exposed mouse monocyte RAW264.7 cells. Scientific reports. vol 9. issue 1. 2020-10-22. PMID:31439879. |
here, we show that autophagy induces fas (cd95/apo-1)-mediated apoptosis by promoting accumulation of p62/sqstm1 in response to cd. |
2020-10-22 |
2023-08-13 |
mouse |
| Ki-Tae Jung, Seon-Hee O. Polyubiquitination of p62/SQSTM1 is a prerequisite for Fas/CD95 aggregation to promote caspase-dependent apoptosis in cadmium-exposed mouse monocyte RAW264.7 cells. Scientific reports. vol 9. issue 1. 2020-10-22. PMID:31439879. |
together, these data suggest that polyub-p62 targets fas and recruits it to autophagosomes, where fas transiently aggregates to promote apoptosis and is degraded with polyub-p62. |
2020-10-22 |
2023-08-13 |
mouse |
| Ki-Tae Jung, Seon-Hee O. Polyubiquitination of p62/SQSTM1 is a prerequisite for Fas/CD95 aggregation to promote caspase-dependent apoptosis in cadmium-exposed mouse monocyte RAW264.7 cells. Scientific reports. vol 9. issue 1. 2020-10-22. PMID:31439879. |
in conclusion, autophagy regulates c-terminal cytosolic fas aggregation via p62 polyubiquitination, which is required for apoptosis and may play a critical role in the production of select cytokines. |
2020-10-22 |
2023-08-13 |
mouse |
| Milad Ashrafizadeh, Shahram Taeb, Hamed Haghi-Aminjan, Shima Afrashi, Kave Moloudi, Ahmed E Musa, Masoud Najafi, Bagher Farhoo. Resveratrol as an Enhancer of Apoptosis in Cancer: A Mechanistic Review. Anti-cancer agents in medicinal chemistry. 2020-10-21. PMID:33081687. |
resveratrol can augment reduction/oxidation (redox) reactions, thus increases the production of ceramide and the expression of apoptosis receptors such as fas ligand (fasl). |
2020-10-21 |
2023-08-13 |
Not clear |
| Ha Thanh Nguyen, Jean-Philippe Guégan, Amanda Poissonnier, Florence Jouan, Daniel Best, Pierre van de Weghe, Pierre Vacher, Nicolas Levoin, Patrick Legembre, Mickael Jea. Synthesis of peptidomimetics and chemo-biological tools for CD95/PLCγ1 interaction analysis. Bioorganic & medicinal chemistry letters. vol 29. issue 16. 2020-10-15. PMID:31301931. |
the death receptor cd95 (also known as fas) induces apoptosis through protein/protein association and the formation of the death-inducing signaling complex. |
2020-10-15 |
2023-08-13 |
Not clear |