| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daima Ord, Kati Meerits, Tõnis Or. TRB3 protects cells against the growth inhibitory and cytotoxic effect of ATF4. Experimental cell research. vol 313. issue 16. 2007-11-05. PMID:17707795. |
also, the coexpression of trb3 rescues postmitotic neuronally differentiated pc12 cells from the apoptosis evoked by atf4 overexpression. |
2007-11-05 |
2023-08-12 |
Not clear |
| Kazuyoshi Kumagai, Yosuke Ando, Naoki Kiyosawa, Kazumi Ito, Ryota Kawai, Takashi Yamoto, Sunao Manabe, Munehiro Teranish. Toxicoproteomic investigation of the molecular mechanisms of cycloheximide-induced hepatocellular apoptosis in rat liver. Toxicology. vol 228. issue 2-3. 2007-01-04. PMID:17067731. |
in the gene expression assay using quantitative rt-pcr, the genes related to chop-mediated apoptosis such as the c/ebpbeta, atf3 and atf4 genes were significantly increased corresponding to the induction of hepatocellular apoptosis in rats treated with chx. |
2007-01-04 |
2023-08-12 |
rat |
| Reshma Shringarpure, Laurence Catley, Deepak Bhole, Renate Burger, Klaus Podar, Yu-Tzu Tai, Benedikt Kessler, Paul Galardy, Hidde Ploegh, Pierfrancesco Tassone, Teru Hideshima, Constantine Mitsiades, Nikhil C Munshi, Dharminder Chauhan, Kenneth C Anderso. Gene expression analysis of B-lymphoma cells resistant and sensitive to bortezomib. British journal of haematology. vol 134. issue 2. 2006-08-04. PMID:16846475. |
we showed that overexpression of activating transcription factor 3 (atf3), atf4, atf5, c-jun, jund and caspase-3 is associated with sensitivity to bortezomib-induced apoptosis, whereas overexpression of heat shock protein (hsp)27, hsp70, hsp90 and t-cell factor 4 is associated with bortezomib resistance. |
2006-08-04 |
2023-08-12 |
Not clear |
| Elizabeth Karaskov, Cameron Scott, Liling Zhang, Tracy Teodoro, Mariella Ravazzola, Allen Volchu. Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic beta-cell apoptosis. Endocrinology. vol 147. issue 7. 2006-07-24. PMID:16601139. |
ins-1 cells exposed to palmitate for 16-24 h under serum-free conditions showed marked apoptosis and increased protein levels of phosphorylated eukaryotic translation initiation factor 2alpha (eif2alpha), activating transcription factor 4 (atf4), x box-binding protein 1 (xbp-1), and c/ebp homologous transcription factor (chop) compared with control cells. |
2006-07-24 |
2023-08-12 |
Not clear |
| R C Wek, H-Y Jiang, T G Anthon. Coping with stress: eIF2 kinases and translational control. Biochemical Society transactions. vol 34. issue Pt 1. 2006-03-27. PMID:16246168. |
atf4 also enhances the expression of additional transcription factors, atf3 and chop (ccaat/enhancer-binding protein homologous protein)/gadd153 (growth arrest and dna-damage-inducible protein), that assist in the regulation of genes involved in metabolism, the redox status of the cells and apoptosis. |
2006-03-27 |
2023-08-12 |
mouse |
| Soo Jung Kim, Kyung Mi Park, Nayoung Kim, Young Il Yeo. Doxorubicin prevents endoplasmic reticulum stress-induced apoptosis. Biochemical and biophysical research communications. vol 339. issue 2. 2006-02-07. PMID:16298333. |
in contrast to another topoisomerase inhibitor, etoposide, doxorubicin markedly decreased apoptosis induced by thapsigargin; this doxorubicin effect was accompanied by reduced expression of the upr-specific proapoptotic protein, c/ebp-homologous protein, and its upstream transcription factor, atf4. |
2006-02-07 |
2023-08-12 |
human |
| Melissa L Fishel, Cara A Rabik, Wasim K Bleibel, Xinmin Li, Robert C Moschel, M Eileen Dola. Role of GADD34 in modulation of cisplatin cytotoxicity. Biochemical pharmacology. vol 71. issue 3. 2006-02-03. PMID:16325149. |
among the overexpressed probe sets were genes involved in dna damage and apoptosis, including gadd34, ddit4, atf4, and pthlh. |
2006-02-03 |
2023-08-12 |
Not clear |
| S Jean, C Bideau, L Bellon, G Halimi, M De Méo, T Orsière, G Dumenil, J L Bergé-Lefranc, A Bott. The expression of genes induced in melanocytes by exposure to 365-nm UVA: study by cDNA arrays and real-time quantitative RT-PCR. Biochimica et biophysica acta. vol 1522. issue 2. 2002-02-05. PMID:11750059. |
these genes included genes involved in cell cycle regulation (gadd45, cip1/waf1), in stress response (hsp70, hsp40, hsp86), in apoptosis (gadd153, tristetraproline) and genes encoding transcription factors (egr-1, etr-101, c-jun, atf4). |
2002-02-05 |
2023-08-12 |
human |