| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Csaba Tóth, Farkas Sükösd, Erzsébet Valicsek, Esther Herpel, Peter Schirmacher, Marcus Renner, Christoph Mader, László Tiszlavicz, Jörg Kriegsman. Expression of ERCC1, RRM1, TUBB3 in correlation with apoptosis repressor ARC, DNA mismatch repair proteins and p53 in liver metastasis of colorectal cancer. International journal of molecular medicine. vol 40. issue 5. 2018-05-30. PMID:28949378. |
expression of ercc1, rrm1, tubb3 in correlation with apoptosis repressor arc, dna mismatch repair proteins and p53 in liver metastasis of colorectal cancer. |
2018-05-30 |
2023-08-13 |
Not clear |
| Csaba Tóth, Farkas Sükösd, Erzsébet Valicsek, Esther Herpel, Peter Schirmacher, Marcus Renner, Christoph Mader, László Tiszlavicz, Jörg Kriegsman. Expression of ERCC1, RRM1, TUBB3 in correlation with apoptosis repressor ARC, DNA mismatch repair proteins and p53 in liver metastasis of colorectal cancer. International journal of molecular medicine. vol 40. issue 5. 2018-05-30. PMID:28949378. |
in statistical analysis, we compared the expression of ercc1, rrm1 and tubb3 to mismatch proteins (mlh1, msh2, msh6 and pms2), p53 and to apoptosis repressor protein (arc). |
2018-05-30 |
2023-08-13 |
Not clear |
| Jie Zhang, Zeyu Wu, Ming Guan, Hongyan Lu, Xuming M. Inhibition of ARC promoting the apoptosis of rat pulmonary arterial smooth muscle cells after serum deprivation in vitro. Molecular medicine reports. vol 16. issue 4. 2018-05-14. PMID:28731195. |
inhibition of arc promoting the apoptosis of rat pulmonary arterial smooth muscle cells after serum deprivation in vitro. |
2018-05-14 |
2023-08-13 |
rat |
| Jie Zhang, Zeyu Wu, Ming Guan, Hongyan Lu, Xuming M. Inhibition of ARC promoting the apoptosis of rat pulmonary arterial smooth muscle cells after serum deprivation in vitro. Molecular medicine reports. vol 16. issue 4. 2018-05-14. PMID:28731195. |
apoptosis repressor with caspase recruitment domain (arc) is an essential factor in cell apoptosis, and regulates intrinsic and extrinsic apoptosis signaling pathways. |
2018-05-14 |
2023-08-13 |
rat |
| Jie Zhang, Zeyu Wu, Ming Guan, Hongyan Lu, Xuming M. Inhibition of ARC promoting the apoptosis of rat pulmonary arterial smooth muscle cells after serum deprivation in vitro. Molecular medicine reports. vol 16. issue 4. 2018-05-14. PMID:28731195. |
it was demonstrated that the expression of arc in pasmcs was significantly increased following sd stimulation within 24 h, and arc downregulation using small interfering rna significantly enhanced the apoptosis of pasmcs following sd stimulation. |
2018-05-14 |
2023-08-13 |
rat |
| Jie Zhang, Zeyu Wu, Ming Guan, Hongyan Lu, Xuming M. Inhibition of ARC promoting the apoptosis of rat pulmonary arterial smooth muscle cells after serum deprivation in vitro. Molecular medicine reports. vol 16. issue 4. 2018-05-14. PMID:28731195. |
in addition, the results demonstrated that arc downregulation significantly increased the expression of proapoptotic factors and the level of reactive oxygen species (ros), and decreased the mitochondrial membrane potential following sd exposure, suggesting arc regulates the apoptosis of pasmcs via modulating mitochondrial function and ros accumulation. |
2018-05-14 |
2023-08-13 |
rat |
| Jie Zhang, Zeyu Wu, Ming Guan, Hongyan Lu, Xuming M. Inhibition of ARC promoting the apoptosis of rat pulmonary arterial smooth muscle cells after serum deprivation in vitro. Molecular medicine reports. vol 16. issue 4. 2018-05-14. PMID:28731195. |
the results of the present study revealed that arc inhibition promotes the apoptosis of pasmcs following sd stimulation, and that arc expression increases in the early stages of sd injury. |
2018-05-14 |
2023-08-13 |
rat |
| Csaba Toth, Sarah Funke, Vanessa Nitsche, Anna Liverts, Viktoriya Zlachevska, Marcia Gasis, Constanze Wiek, Helmut Hanenberg, Csaba Mahotka, Peter Schirmacher, Sebastian Heikau. The role of apoptosis repressor with a CARD domain (ARC) in the therapeutic resistance of renal cell carcinoma (RCC): the crucial role of ARC in the inhibition of extrinsic and intrinsic apoptotic signalling. Cell communication and signaling : CCS. vol 15. issue 1. 2018-02-28. PMID:28464919. |
the role of apoptosis repressor with a card domain (arc) in the therapeutic resistance of renal cell carcinoma (rcc): the crucial role of arc in the inhibition of extrinsic and intrinsic apoptotic signalling. |
2018-02-28 |
2023-08-13 |
Not clear |
| Csaba Toth, Sarah Funke, Vanessa Nitsche, Anna Liverts, Viktoriya Zlachevska, Marcia Gasis, Constanze Wiek, Helmut Hanenberg, Csaba Mahotka, Peter Schirmacher, Sebastian Heikau. The role of apoptosis repressor with a CARD domain (ARC) in the therapeutic resistance of renal cell carcinoma (RCC): the crucial role of ARC in the inhibition of extrinsic and intrinsic apoptotic signalling. Cell communication and signaling : CCS. vol 15. issue 1. 2018-02-28. PMID:28464919. |
one important anti-apoptotic factor that is strongly overexpressed in rccs and known to inhibit both apoptotic pathways is arc (apoptosis repressor with a card domain). |
2018-02-28 |
2023-08-13 |
Not clear |
| Ming Guan, Qiaojun Fang, Zuhong He, Yong Li, Fuping Qian, Xiaoyun Qian, Ling Lu, Xiaoli Zhang, Dingding Liu, Jieyu Qi, Shasha Zhang, Mingliang Tang, Xia Gao, Renjie Cha. Inhibition of ARC decreases the survival of HEI-OC-1 cells after neomycin damage in vitro. Oncotarget. vol 7. issue 41. 2018-02-12. PMID:27556499. |
apoptosis repressor with caspase recruitment domain(arc) is a key factor in apoptosis that inhibits both intrinsic and extrinsic apoptosis pathways; however, there have been no reports on the role of arc in hc loss in the inner ear. |
2018-02-12 |
2023-08-13 |
Not clear |
| Ming Guan, Qiaojun Fang, Zuhong He, Yong Li, Fuping Qian, Xiaoyun Qian, Ling Lu, Xiaoli Zhang, Dingding Liu, Jieyu Qi, Shasha Zhang, Mingliang Tang, Xia Gao, Renjie Cha. Inhibition of ARC decreases the survival of HEI-OC-1 cells after neomycin damage in vitro. Oncotarget. vol 7. issue 41. 2018-02-12. PMID:27556499. |
finally, we found that arc inhibition increased the expression of pro-apoptotic factors, decreased the mitochondrial membrane potential, and increased the level of reactive oxygen species (ros) after neomycin injury, suggesting that arc inhibits cell death and apoptosis in hei-oc-1 cells by controlling mitochondrial function and ros accumulation. |
2018-02-12 |
2023-08-13 |
Not clear |
| Ike Dela Peña, Irene Joy Dela Peña, June Bryan de la Peña, Hee Jin Kim, Chan Young Shin, Doug Hyun Han, Bung-Nyun Kim, Jong Hoon Ryu, Jae Hoon Cheon. Methylphenidate and Atomoxetine-Responsive Prefrontal Cortical Genetic Overlaps in "Impulsive" SHR/NCrl and Wistar Rats. Behavior genetics. vol 47. issue 5. 2018-02-05. PMID:28744604. |
prefrontal cortical genetic overlaps between shr/ncrl and wistar rats in comparison with wky/ncrl included genes associated with transcription (e.g., btg2, fos, nr4a2), synaptic plasticity (e.g., arc, homer2), and neuron apoptosis (grik2, nmnat1). |
2018-02-05 |
2023-08-13 |
rat |
| Bing Z Carter, Po Yee Mak, Ye Chen, Duncan H Mak, Hong Mu, Rodrigo Jacamo, Vivian Ruvolo, Stefan T Arold, John E Ladbury, Jared K Burks, Steven Kornblau, Michael Andreef. Anti-apoptotic ARC protein confers chemoresistance by controlling leukemia-microenvironment interactions through a NFκB/IL1β signaling network. Oncotarget. vol 7. issue 15. 2018-01-17. PMID:26956049. |
to better understand how the apoptosis repressor with caspase recruitment domain (arc) protein confers drug resistance in acute myeloid leukemia (aml), we investigated the role of arc in regulating leukemia-mesenchymal stromal cell (msc) interactions. |
2018-01-17 |
2023-08-13 |
mouse |
| Bing Z Carter, Po Yee Mak, Ye Chen, Duncan H Mak, Hong Mu, Rodrigo Jacamo, Vivian Ruvolo, Stefan T Arold, John E Ladbury, Jared K Burks, Steven Kornblau, Michael Andreef. Anti-apoptotic ARC protein confers chemoresistance by controlling leukemia-microenvironment interactions through a NFκB/IL1β signaling network. Oncotarget. vol 7. issue 15. 2018-01-17. PMID:26956049. |
in addition to the previously reported effect on aml apoptosis, we have demonstrated that arc enhances migration and adhesion of leukemia cells to mscs both in vitro and in a novel human extramedullary bone/bone marrow mouse model. |
2018-01-17 |
2023-08-13 |
mouse |
| Hyun Ji Ha, Hyun Ho Par. Molecular basis for the effect of the L31F mutation on CARD function in ARC. FEBS letters. vol 591. issue 18. 2017-10-11. PMID:28792591. |
the apoptosis repressor with caspase-recruiting domain (arc) is aberrantly overexpressed in various cancers. |
2017-10-11 |
2023-08-13 |
Not clear |
| Andrew T Templin, Tanya Samarasekera, Daniel T Meier, Meghan F Hogan, Mahnaz Mellati, Michael T Crow, Richard N Kitsis, Sakeneh Zraika, Rebecca L Hull, Steven E Kah. Apoptosis Repressor With Caspase Recruitment Domain Ameliorates Amyloid-Induced β-Cell Apoptosis and JNK Pathway Activation. Diabetes. vol 66. issue 10. 2017-10-02. PMID:28729244. |
apoptosis repressor with caspase recruitment domain (arc) binds and inactivates components of the intrinsic and extrinsic apoptosis pathways and was recently found to be expressed in islet β-cells. |
2017-10-02 |
2023-08-13 |
mouse |
| Andrew T Templin, Tanya Samarasekera, Daniel T Meier, Meghan F Hogan, Mahnaz Mellati, Michael T Crow, Richard N Kitsis, Sakeneh Zraika, Rebecca L Hull, Steven E Kah. Apoptosis Repressor With Caspase Recruitment Domain Ameliorates Amyloid-Induced β-Cell Apoptosis and JNK Pathway Activation. Diabetes. vol 66. issue 10. 2017-10-02. PMID:28729244. |
using a human islet amyloid polypeptide transgenic mouse model of islet amyloidosis, we show arc knockdown increases amyloid-induced β-cell apoptosis and loss, while arc overexpression decreases amyloid-induced apoptosis, thus preserving β-cells. |
2017-10-02 |
2023-08-13 |
mouse |
| Stefan Donath, Junfeng An, Sabrina Lin Lin Lee, Karen Gertz, Anna Lena Datwyler, Ulrike Harms, Susanne Müller, Tracy Deanne Farr, Martina Füchtemeier, Gisela Lättig-Tünnemann, Janet Lips, Marco Foddis, Larissa Mosch, René Bernard, Ulrike Grittner, Mustafa Balkaya, Golo Kronenberg, Ulrich Dirnagl, Matthias Endres, Christoph Harm. Interaction of ARC and Daxx: A Novel Endogenous Target to Preserve Motor Function and Cell Loss after Focal Brain Ischemia in Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 31. 2017-07-10. PMID:27488634. |
the aim of this study was to explore the signaling and neuroprotective effect of transactivator of transcription (tat) protein transduction of the apoptosis repressor with card (arc) in in vitro and in vivo models of cerebral ischemia in mice. |
2017-07-10 |
2023-08-13 |
mouse |
| Manuela Magarin, Toni Pohl, Anette Lill, Herbert Schulz, Florian Blaschke, Arnd Heuser, Ludwig Thierfelder, Stefan Donath, Jörg-Detlef Drenckhah. Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress. Journal of molecular and cellular cardiology. vol 97. 2017-05-31. PMID:27106802. |
whereas most apoptosis inhibitors are either unchanged or downregulated in hccs deficient cardiomyocytes, bcl-2 and arc (apoptosis repressor with caspase recruitment domain) are induced. |
2017-05-31 |
2023-08-13 |
mouse |
| Yo-Han Han, Ji-Ye Kee, Dae-Seung Kim, Jeong-Geon Mun, Mi-Young Jeong, Sang-Hyun Park, Byung-Min Choi, Sung-Joo Park, Hyun-Jung Kim, Jae-Young Um, Seung-Heon Hon. Arctigenin Inhibits Lung Metastasis of Colorectal Cancer by Regulating Cell Viability and Metastatic Phenotypes. Molecules (Basel, Switzerland). vol 21. issue 9. 2017-04-17. PMID:27618887. |
arc induced cell cycle arrest and apoptosis in ct26 cells through the intrinsic apoptotic pathway via mapks signaling. |
2017-04-17 |
2023-08-13 |
Not clear |