| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ting Zhang, Pengyuan Dai, Dong Cheng, Liang Zhang, Zijiang Chen, Xiaoqian Meng, Fumiao Zhang, Xiaoying Han, Jianwei Liu, Jie Pan, Guiwen Yang, Cong Zhan. Obesity occurring in apolipoprotein E-knockout mice has mild effects on fertility. Reproduction (Cambridge, England). vol 147. issue 2. 2014-08-26. PMID:24196014. |
however, the deletion of apoe increased the number of ovarian follicles and the ratio of ovarian follicle atresia and apoptosis. |
2014-08-26 |
2023-08-12 |
mouse |
| Jingjing Zhuang, Haikun Zhang, Rong Zhou, Lili Chen, Jing Chen, Xu She. Regulation of prostaglandin F2α against β amyloid clearance and its inflammation induction through LXR/RXR heterodimer antagonism in microglia. Prostaglandins & other lipid mediators. vol 106. 2014-07-10. PMID:24076168. |
cell based assays indicated that pgf2α effectively antagonized the activation of lxr agonist (t0901317) on aβ clearance via inhibiting apolipoprotein e (apoe) expression, and cell apoptosis alleviation by accelerating inflammatory response to aβ or lipopolysaccharide (lps) in microglia. |
2014-07-10 |
2023-08-12 |
Not clear |
| Jian-Fei Li, Song Chen, Jun-Duo Feng, Ming-Yu Zhang, Xiao-Xia Li. Probucol via inhibition of NHE1 attenuates LPS-accelerated atherosclerosis and promotes plaque stability in vivo. Experimental and molecular pathology. vol 96. issue 2. 2014-05-28. PMID:24594116. |
animal studies indicated administration of probucol suppressed lps-accelerated apoptosis, atherosclerosis and plaque instability in apoe(-/-) mice. |
2014-05-28 |
2023-08-12 |
mouse |
| Li-jun Wang, Xiao-lin Liu, Hong-liang Wang, Hua He, Zhi-xiong Li, Ling Che. Expression analysis, single nucleotide polymorphisms and combined genotypes in candidate genes and their associations with growth and carcass traits in Qinchuan cattle. Molecular biology reports. vol 40. issue 3. 2014-03-03. PMID:23196708. |
the apolipoprotein e (apoe) gene is an important component of plasma lipoprotein, and fas apoptosis inhibitory molecule (faim) is a novel anti-apoptotic gene. |
2014-03-03 |
2023-08-12 |
cattle |
| Maciej Suski, Rafał Olszanecki, Aneta Stachowicz, Józef Madej, Beata Bujak-Giżycka, Krzysztof Okoń, Ryszard Korbu. The influence of angiotensin-(1-7) Mas receptor agonist (AVE 0991) on mitochondrial proteome in kidneys of apoE knockout mice. Biochimica et biophysica acta. vol 1834. issue 12. 2014-02-21. PMID:23988828. |
proteins changed in apoe(-/-) mice belonged to the groups of antioxidant enzymes, apoptosis regulators, inflammatory factors and metabolic enzymes. |
2014-02-21 |
2023-08-12 |
mouse |
| Luyi Mao, Qiongjie Zhou, Shufeng Zhou, Rhonda R Wilbur, Xiaotian L. Roles of apolipoprotein E (ApoE) and inducible nitric oxide synthase (iNOS) in inflammation and apoptosis in preeclampsia pathogenesis and progression. PloS one. vol 8. issue 3. 2013-12-03. PMID:23472151. |
roles of apolipoprotein e (apoe) and inducible nitric oxide synthase (inos) in inflammation and apoptosis in preeclampsia pathogenesis and progression. |
2013-12-03 |
2023-08-12 |
mouse |
| Luyi Mao, Qiongjie Zhou, Shufeng Zhou, Rhonda R Wilbur, Xiaotian L. Roles of apolipoprotein E (ApoE) and inducible nitric oxide synthase (iNOS) in inflammation and apoptosis in preeclampsia pathogenesis and progression. PloS one. vol 8. issue 3. 2013-12-03. PMID:23472151. |
to investigate potential roles of inducible nitric oxide synthase (inos) and apolipoprotein (apoe) in inflammation and apoptosis promoting pathological changes in preeclampsia in pregnant mice with apoe and/or inos knock out. |
2013-12-03 |
2023-08-12 |
mouse |
| Shengchao Ma, Huiping Zhang, Weiwei Sun, Huihui Gong, Yanhua Wang, Changjian Ma, Ju Wang, Chengjian Cao, Xiaoling Yang, Jue Tian, Yideng Jian. Hyperhomocysteinemia induces cardiac injury by up-regulation of p53-dependent Noxa and Bax expression through the p53 DNA methylation in ApoE(-/-) mice. Acta biochimica et biophysica Sinica. vol 45. issue 5. 2013-10-28. PMID:23619570. |
to elucidate the role of p53-dependent apoptosis in hhcy-induced cardiac injury, we fed apoe(-/-) mice with high methionine diet to establish hhcy model. |
2013-10-28 |
2023-08-12 |
mouse |
| Chaoyong He, Huaiping Zhu, Wencheng Zhang, Imoh Okon, Qilong Wang, Hongliang Li, Yun-Zheng Le, Zhonglin Xi. 7-Ketocholesterol induces autophagy in vascular smooth muscle cells through Nox4 and Atg4B. The American journal of pathology. vol 183. issue 2. 2013-10-24. PMID:23770348. |
finally, activation of autophagy by chronic rapamycin treatment attenuated er stress, apoptosis, and atherosclerosis in apolipoprotein e knockout (apoe(-/-)) mouse aortas. |
2013-10-24 |
2023-08-12 |
mouse |
| Le Su, Haiyan Zhang, Jing Zhao, Shangli Zhang, Yun Zhang, Baoxiang Zhao, Junying Mia. Safrole-2',3'-oxide induces atherosclerotic plaque vulnerability in apolipoprotein E-knockout mice. Toxicology letters. vol 217. issue 2. 2013-06-19. PMID:23270965. |
thus, sfo contributes to the instability of atherosclerotic plaque in apoe(-/-) mice through activating p75(ntr) and il-8 and cell apoptosis in plaque. |
2013-06-19 |
2023-08-12 |
mouse |
| Shuai Zhou, Haitao Wu, Chun Zeng, Xuehua Xiong, Shuang Tang, Zhaohua Tang, Xiaochuan Su. Apolipoprotein E protects astrocytes from hypoxia and glutamate-induced apoptosis. FEBS letters. vol 587. issue 2. 2013-03-07. PMID:23238080. |
in this study, we investigated the role of apoe in astrocyte apoptosis. |
2013-03-07 |
2023-08-12 |
mouse |
| Shuai Zhou, Haitao Wu, Chun Zeng, Xuehua Xiong, Shuang Tang, Zhaohua Tang, Xiaochuan Su. Apolipoprotein E protects astrocytes from hypoxia and glutamate-induced apoptosis. FEBS letters. vol 587. issue 2. 2013-03-07. PMID:23238080. |
we demonstrated that apoe protects astrocytes from hypoxia-induced apoptosis in a dose-dependent manner. |
2013-03-07 |
2023-08-12 |
mouse |
| Shuai Zhou, Haitao Wu, Chun Zeng, Xuehua Xiong, Shuang Tang, Zhaohua Tang, Xiaochuan Su. Apolipoprotein E protects astrocytes from hypoxia and glutamate-induced apoptosis. FEBS letters. vol 587. issue 2. 2013-03-07. PMID:23238080. |
finally, the apoe activator t0901317 significantly reduced the effect of glutamate-induced apoptosis of astrocytes. |
2013-03-07 |
2023-08-12 |
mouse |
| Shuai Zhou, Haitao Wu, Chun Zeng, Xuehua Xiong, Shuang Tang, Zhaohua Tang, Xiaochuan Su. Apolipoprotein E protects astrocytes from hypoxia and glutamate-induced apoptosis. FEBS letters. vol 587. issue 2. 2013-03-07. PMID:23238080. |
these results suggest that apoe protects astrocytes from hypoxia-induced apoptosis associated to nmda receptor activation. |
2013-03-07 |
2023-08-12 |
mouse |
| Dawei Zhang, Li Jin, Davis L Reames, Francis H Shen, Adam L Shimer, Xudong L. Intervertebral disc degeneration and ectopic bone formation in apolipoprotein E knockout mice. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 31. issue 2. 2013-02-28. PMID:22915292. |
apoptosis was increased in the apoe ko np tissue. |
2013-02-28 |
2023-08-12 |
mouse |
| Claudio Contaldo, Dominik C Högger, Meisam Khorrami Borozadi, Michael Stotz, Uwe Platz, Natasha Forster, Nicole Lindenblatt, Pietro Giovanol. Radial pressure waves mediate apoptosis and functional angiogenesis during wound repair in ApoE deficient mice. Microvascular research. vol 84. issue 1. 2012-11-01. PMID:22504489. |
radial pressure waves mediate apoptosis and functional angiogenesis during wound repair in apoe deficient mice. |
2012-11-01 |
2023-08-12 |
mouse |
| Yuehai Wang, Ziyang Huang, Huixia Lu, Huili Lin, Zhenhua Wang, Xiaoqing Chen, Qiufang Ouyang, Mengxiong Tang, Panpan Hao, Jingqin Ni, Dongming Xu, Mingxiang Zhang, Qunye Zhang, Ling Lin, Yun Zhan. Apolipoprotein E-knockout mice show increased titers of serum anti-nuclear and anti-dsDNA antibodies. Biochemical and biophysical research communications. vol 423. issue 4. 2012-10-22. PMID:22713470. |
we also survey the changes of serum autoantibodies, spleen weight, splenocyte apoptosis and the expressions of tlr4, myd88, pp38, irf3 and bax in spleen tissue in male apoe(-/-) mice after 4weeks of lipopolysaccharide (lps), toll-like receptor 4 ligand, administration. |
2012-10-22 |
2023-08-12 |
mouse |
| Yuehai Wang, Ziyang Huang, Huixia Lu, Huili Lin, Zhenhua Wang, Xiaoqing Chen, Qiufang Ouyang, Mengxiong Tang, Panpan Hao, Jingqin Ni, Dongming Xu, Mingxiang Zhang, Qunye Zhang, Ling Lin, Yun Zhan. Apolipoprotein E-knockout mice show increased titers of serum anti-nuclear and anti-dsDNA antibodies. Biochemical and biophysical research communications. vol 423. issue 4. 2012-10-22. PMID:22713470. |
splenocyte apoptosis and the expression of tlr4, myd88, pp38, irf3 and bax in spleen tissue were significantly lower in apoe(-/-) than b6 mice. |
2012-10-22 |
2023-08-12 |
mouse |
| Yuehai Wang, Ziyang Huang, Huixia Lu, Huili Lin, Zhenhua Wang, Xiaoqing Chen, Qiufang Ouyang, Mengxiong Tang, Panpan Hao, Jingqin Ni, Dongming Xu, Mingxiang Zhang, Qunye Zhang, Ling Lin, Yun Zhan. Apolipoprotein E-knockout mice show increased titers of serum anti-nuclear and anti-dsDNA antibodies. Biochemical and biophysical research communications. vol 423. issue 4. 2012-10-22. PMID:22713470. |
therefore, the tlr4 signal pathway may participate in maintaining the balance of splenocyte apoptosis and autoantibody production in apoe(-/-) mice. |
2012-10-22 |
2023-08-12 |
mouse |
| Soojeong Jang, Yunsook Lim, Giuseppe Valacchi, Sungbin Sorn, Hyon Park, Na-Young Park, Myoungsook Le. Preventive effects of protopanaxadiol and protopanaxatriol ginsenosides on liver inflammation and apoptosis in hyperlipidemic apoE KO mice. Genes & nutrition. vol 7. issue 2. 2012-10-02. PMID:21853335. |
preventive effects of protopanaxadiol and protopanaxatriol ginsenosides on liver inflammation and apoptosis in hyperlipidemic apoe ko mice. |
2012-10-02 |
2023-08-12 |
mouse |