| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ying Lin, Jianhui Zhuang, Hailing Li, Guofu Zhu, Shunping Zhou, Weiming Li, Wenhui Peng, Yawei X. Vaspin attenuates the progression of atherosclerosis by inhibiting ER stress-induced macrophage apoptosis in apoE‑/‑ mice. Molecular medicine reports. vol 13. issue 2. 2016-10-31. PMID:26708512. |
the results of the current study indicated that vaspin inhibited the progression of atherosclerotic plaques in apoe(‑/‑) mice by inhibiting endoplasmic reticulum stress-induced macrophage apoptosis. |
2016-10-31 |
2023-08-13 |
mouse |
| R Stanzione, S Sciarretta, S Marchitti, F Bianchi, S Di Castro, S Scarpino, M Cotugno, G Frati, M Volpe, S Rubatt. C2238/αANP modulates apolipoprotein E through Egr-1/miR199a in vascular smooth muscle cells in vitro. Cell death & disease. vol 6. 2016-09-19. PMID:26720342. |
of note, downregulation of apoe by c2238/αanp was associated with a significant increase in inflammation, apoptosis and necrosis that was completely rescued by the exogenous administration of recombinant apoe. |
2016-09-19 |
2023-08-13 |
human |
| Chao Chen, Guangqing Cheng, Xiaoni Yang, Changsheng Li, Ran Shi, Ningning Zha. Tanshinol suppresses endothelial cells apoptosis in mice with atherosclerosis via lncRNA TUG1 up-regulating the expression of miR-26a. American journal of translational research. vol 8. issue 7. 2016-08-10. PMID:27508018. |
apoe(-/-)mice were fed with a high-fat diet and treated with tanshinol to detect the effect of tanshinol on endothelial cells apoptosis with tunel staining assay. |
2016-08-10 |
2023-08-13 |
mouse |
| Chao Chen, Guangqing Cheng, Xiaoni Yang, Changsheng Li, Ran Shi, Ningning Zha. Tanshinol suppresses endothelial cells apoptosis in mice with atherosclerosis via lncRNA TUG1 up-regulating the expression of miR-26a. American journal of translational research. vol 8. issue 7. 2016-08-10. PMID:27508018. |
it has been shown that tanshinol reduced the aortic atherosclerotic lesion area in the entire aorta and aortic sinus in a concentration dependent manner, and suppressed the endothelial cells apoptosis in apoe(-/-) mice. |
2016-08-10 |
2023-08-13 |
mouse |
| Chao Chen, Guangqing Cheng, Xiaoni Yang, Changsheng Li, Ran Shi, Ningning Zha. Tanshinol suppresses endothelial cells apoptosis in mice with atherosclerosis via lncRNA TUG1 up-regulating the expression of miR-26a. American journal of translational research. vol 8. issue 7. 2016-08-10. PMID:27508018. |
taken together, our study reveals that tanshinol could attenuate the endothelial cells apoptosis in atherosclerotic apoe(-/-) mice. |
2016-08-10 |
2023-08-13 |
mouse |
| Lan Li, Jing-Cai Liu, Fang-Nong Lai, Huan-Qi Liu, Xi-Feng Zhang, Paul W Dyce, Wei Shen, Hong Che. Di (2-ethylhexyl) Phthalate Exposure Impairs Growth of Antral Follicle in Mice. PloS one. vol 11. issue 2. 2016-08-01. PMID:26845775. |
the mrna levels of the apoptosis and cell proliferation (negative) related genes apoe, agt, glo1 and grina were increased after dehp exposure. |
2016-08-01 |
2023-08-13 |
mouse |
| Meijuan Ma, Liqiang Song, Hao Yan, Min Liu, Le Zhang, Ying Ma, Jian Yuan, Jianhua Hu, Zhaole Ji, Rongqing Zhang, Congye Li, Haichang Wang, Ling Tao, Yingmei Zhang, Yan L. Low dose tunicamycin enhances atherosclerotic plaque stability by inducing autophagy. Biochemical pharmacology. vol 100. 2016-06-22. PMID:26616221. |
in addition, we found that the apoe(-/-) mice presented higher autophagy activity in response to lower tm administration while apoptosis was reduced. |
2016-06-22 |
2023-08-13 |
mouse |
| Xi Wu, Yong-Fen Qi, Jin-Rui Chang, Wei-Wei Lu, Jin-Sheng Zhang, Shao-Ping Wang, Shu-Juan Cheng, Ming Zhang, Qian Fan, Yuan Lv, Hui Zhu, Man-Kun Xin, Yun Lv, Jing-Hua Li. Possible role of fibroblast growth factor 21 on atherosclerosis via amelioration of endoplasmic reticulum stress-mediated apoptosis in apoE(-/-) mice. Heart and vessels. vol 30. issue 5. 2016-06-07. PMID:25092223. |
possible role of fibroblast growth factor 21 on atherosclerosis via amelioration of endoplasmic reticulum stress-mediated apoptosis in apoe(-/-) mice. |
2016-06-07 |
2023-08-13 |
mouse |
| L Jiang, J Zhong, X Dou, C Cheng, Z Huang, X Su. Effects of ApoE on intracellular calcium levels and apoptosis of neurons after mechanical injury. Neuroscience. vol 301. 2016-04-18. PMID:26073697. |
effects of apoe on intracellular calcium levels and apoptosis of neurons after mechanical injury. |
2016-04-18 |
2023-08-13 |
Not clear |
| L Jiang, J Zhong, X Dou, C Cheng, Z Huang, X Su. Effects of ApoE on intracellular calcium levels and apoptosis of neurons after mechanical injury. Neuroscience. vol 301. 2016-04-18. PMID:26073697. |
the current study aimed to explore the effects of apolipoprotein e (apoe) on intracellular calcium ([ca(2+)]i) and apoptosis of neurons after mechanical injury in vitro. |
2016-04-18 |
2023-08-13 |
Not clear |
| Valvanera Fernández-Laso, Cristina Sastre, Jesús Egido, Jose L Martín-Ventura, Luis M Blanco-Coli. [Atorvastatin inhibits the atherosclerotic lesion induced by tumor necrosis factor-like weak inducer of apoptosis in apolipoprotein E deficient mice]. Clinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis. vol 27. issue 1. 2016-02-15. PMID:25027757. |
interaction of tumor necrosis factor-like weak inducer of apoptosis (tweak) with its receptor fn14 accelerates atherosclerotic plaque development in apoe deficient mice (apoe ko). |
2016-02-15 |
2023-08-13 |
mouse |
| Wei-Rong Wang, En-Qi Liu, Ji-Ye Zhang, Yan-Xiang Li, Xiao-Feng Yang, Yan-Hao He, Wei Zhang, Ting Jing, Rong Li. Activation of PPAR alpha by fenofibrate inhibits apoptosis in vascular adventitial fibroblasts partly through SIRT1-mediated deacetylation of FoxO1. Experimental cell research. vol 338. issue 1. 2015-12-29. PMID:26226216. |
in this study, we aimed to determine the effect of pparα agonist fenofibrate on cell apoptosis and sirt1 expression and related mechanisms in apoe(-/-) mice and vafs in vitro. |
2015-12-29 |
2023-08-13 |
mouse |
| Wei-Rong Wang, En-Qi Liu, Ji-Ye Zhang, Yan-Xiang Li, Xiao-Feng Yang, Yan-Hao He, Wei Zhang, Ting Jing, Rong Li. Activation of PPAR alpha by fenofibrate inhibits apoptosis in vascular adventitial fibroblasts partly through SIRT1-mediated deacetylation of FoxO1. Experimental cell research. vol 338. issue 1. 2015-12-29. PMID:26226216. |
we found that fenofibrate inhibited cell apoptosis in vascular adventitia and up-regulated sirt1 expression in aorta of apoe(-/-) mice. |
2015-12-29 |
2023-08-13 |
mouse |
| Shutong Yao, Hua Tian, Cheng Miao, Da-Wei Zhang, Li Zhao, Yanyan Li, Nana Yang, Peng Jiao, Hui Sang, Shoudong Guo, Yiwei Wang, Shucun Qi. D4F alleviates macrophage-derived foam cell apoptosis by inhibiting CD36 expression and ER stress-CHOP pathway. Journal of lipid research. vol 56. issue 4. 2015-12-18. PMID:25635126. |
our results showed that treating apoe knockout mice with d4f decreased the serum ox-ldl level and apoptosis in atherosclerotic lesions with concomitant downregulation of cluster of differentiation 36 (cd36) and inhibition of er stress. |
2015-12-18 |
2023-08-13 |
mouse |
| Ligang Chen, Xiaochuan Sun, Yong Jiang, Li Kua. APOEε4 increases trauma induced early apoptosis via reducing delayed rectifier K(+) currents in neuronal/glial co-cultures model. Experimental cell research. vol 334. issue 2. 2015-08-10. PMID:25773779. |
our objective was to evaluate the effects of apoe alleles on trauma induced early apoptosis via modification of delayed rectifier k(+) current (ik(dr)) in neuronal/glial co-cultures model. |
2015-08-10 |
2023-08-13 |
Not clear |
| Ligang Chen, Xiaochuan Sun, Yong Jiang, Li Kua. APOEε4 increases trauma induced early apoptosis via reducing delayed rectifier K(+) currents in neuronal/glial co-cultures model. Experimental cell research. vol 334. issue 2. 2015-08-10. PMID:25773779. |
flow cytometry and patch clamp recording were performed to analyze the correlations among apoe genotypes, early apoptosis and ik(dr). |
2015-08-10 |
2023-08-13 |
Not clear |
| Maryse Lemaire, Catherine A Lemarié, Manuel Flores Molina, Cynthia Guilbert, Stéphanie Lehoux, Koren K Man. Genetic deletion of LXRα prevents arsenic-enhanced atherosclerosis, but not arsenic-altered plaque composition. Toxicological sciences : an official journal of the Society of Toxicology. vol 142. issue 2. 2015-08-06. PMID:25273567. |
we confirmed in vitro that these cells retained more lipid following arsenic exposure and are more sensitive to apoptosis than apoe(-/-). |
2015-08-06 |
2023-08-13 |
mouse |
| Hua-Qing Zhu, Qing li, Liu-Yi Dong, Qing Zhou, Hua Wang, Yuan Wan. MicroRNA-29b promotes high-fat diet-stimulated endothelial permeability and apoptosis in apoE knock-out mice by down-regulating MT1 expression. International journal of cardiology. vol 176. issue 3. 2015-07-20. PMID:25131924. |
microrna-29b promotes high-fat diet-stimulated endothelial permeability and apoptosis in apoe knock-out mice by down-regulating mt1 expression. |
2015-07-20 |
2023-08-13 |
mouse |
| Yimei Liu, Xiaohua Xu, Hongbo Dou, Ying Hua, Jinwen Xu, Xu Hu. Apolipoprotein E knockout induced inflammatory responses related to microglia in neonatal mice brain via astrocytes. International journal of clinical and experimental medicine. vol 8. issue 1. 2015-03-18. PMID:25785051. |
in this study, we aimed to investigate whether apolipoprotein e (apoe) induced inflammatory responses and apoptosis in neonatal mice brain from apoe deficient (apoe(-/-)) and wildtype (wt). |
2015-03-18 |
2023-08-13 |
mouse |
| Sumeet Solanki, Prabhatchandra R Dube, Jean-Yves Tano, Lutz Birnbaumer, Guillermo Vazque. Reduced endoplasmic reticulum stress-induced apoptosis and impaired unfolded protein response in TRPC3-deficient M1 macrophages. American journal of physiology. Cell physiology. vol 307. issue 6. 2014-11-06. PMID:25031020. |
in vitro, proinflammatory m1 but not anti-inflammatory m2 macrophages derived from trpc3(-/-)apoe(-/-) animals exhibited reduced er stress-induced apoptosis. |
2014-11-06 |
2023-08-13 |
mouse |