Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Rodger J Elbl. Tremor and dopamine agonists. Neurology. vol 58. issue 4 Suppl 1. 2003-09-15. PMID:11909986. |
dopamine agonists are particularly well suited for patients with newly diagnosed tremor-predominant disease and no cognitive impairment, but they are also useful in advanced patients with tremor that is refractory to levodopa and anticholinergics. |
2003-09-15 |
2023-08-12 |
Not clear |
Prithiva Navan, Leslie J Findley, Jim A R Jeffs, Ronald K B Pearce, Peter G Bai. Double-blind, single-dose, cross-over study of the effects of pramipexole, pergolide, and placebo on rest tremor and UPDRS part III in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 18. issue 2. 2003-06-04. PMID:12539211. |
it has been postulated that pramipexole may have a stronger antiparkinsonian tremor effect than pergolide, another direct acting dopamine agonist medication, possibly because the former has preferential affinity for the dopamine d3 receptor. |
2003-06-04 |
2023-08-12 |
Not clear |
Regina Katzenschlager, Durval Costa, Willibald Gerschlager, John O'Sullivan, Jan Zijlmans, Svetoslav Gacinovic, Walter Pirker, Adrian Wills, Kailash Bhatia, Andrew J Lees, Peter Brow. [123I]-FP-CIT-SPECT demonstrates dopaminergic deficit in orthostatic tremor. Annals of neurology. vol 53. issue 4. 2003-04-28. PMID:12666116. |
there is increasing evidence of a potential role of the dopaminergic system in orthostatic tremor (ot): association with parkinsonism and treatment effects of l-dopa and dopamine agonists have been reported. |
2003-04-28 |
2023-08-12 |
Not clear |
Michele T M Hu, K Ray Chaudhuri, Jozef Jarosz, Lidia Yaguez, David J Brook. An imaging study of parkinsonism among African-Caribbean and Indian London communities. Movement disorders : official journal of the Movement Disorder Society. vol 17. issue 6. 2003-03-24. PMID:12465076. |
we previously reported on 131 parkinsonian patients of african-caribbean and indian origin attending movement disorders clinics in six london hospitals, of whom approximately 20% manifested atypical parkinsonism with a late-onset, akinetic-rigid predominant syndrome, postural instability and minimal resting tremor refractory to levodopa therapy and dopamine agonists (see hu et al., neurology 2000;54[suppl.3]: a188 and hu et al., mov disord 2000;15[suppl.3]:s212). |
2003-03-24 |
2023-08-12 |
Not clear |
Zitao Zhu, Muriel Bartol, Kezhong Shen, Steven W Johnso. Excitatory effects of dopamine on subthalamic nucleus neurons: in vitro study of rats pretreated with 6-hydroxydopamine and levodopa. Brain research. vol 945. issue 1. 2002-10-07. PMID:12113949. |
increased output from the subthalamic nucleus (stn) following chronic dopamine depletion has been linked to the rigidity and tremor seen in parkinson's disease (pd). |
2002-10-07 |
2023-08-12 |
rat |
[Dopamine agonist is effective in Parkinson disease not only against tremor. Depression is also improved]. MMW Fortschritte der Medizin. vol Suppl 2. 2002-09-03. PMID:12070869. |
[dopamine agonist is effective in parkinson disease not only against tremor. |
2002-09-03 |
2023-08-12 |
Not clear |
Paul J Lockhart, Benjamin Holtom, Sarah Lincoln, Jennifer Hussey, Alexander Zimprich, Thomas Gasser, Zbigniew K Wszolek, John Hardy, Matthew J Farre. The human sideroflexin 5 (SFXN5) gene: sequence, expression analysis and exclusion as a candidate for PARK3. Gene. vol 285. issue 1-2. 2002-06-24. PMID:12039050. |
parkinson's disease (pd) is a common neurodegenerative disorder with clinical features of bradykinesia, rigidity and resting tremor resulting from the deficiency of dopamine in the nigrostriatal system. |
2002-06-24 |
2023-08-12 |
human |
Hagai Bergman, Günther Deusch. Pathophysiology of Parkinson's disease: from clinical neurology to basic neuroscience and back. Movement disorders : official journal of the Movement Disorder Society. vol 17 Suppl 3. 2002-05-10. PMID:11948753. |
dopamine depletion in the striatum is the hallmark of pd and of its animal models, still the pathophysiology of the parkinsonian symptoms and especially of parkinsonian tremor are under debate. |
2002-05-10 |
2023-08-12 |
Not clear |
A Winogrodzka, R C Wagenaar, P Bergmans, A Vellinga, J Booij, E A van Royen, R E van Emmerik, J C Stoof, E C Wolter. Rigidity decreases resting tremor intensity in Parkinson's disease: A [(123)I]beta-CIT SPECT study in early, nonmedicated patients. Movement disorders : official journal of the Movement Disorder Society. vol 16. issue 6. 2002-01-25. PMID:11748734. |
although it is accepted that other classic symptoms of pd such as rigidity and bradykinesia result from a degeneration of the nigrostriatal system and subsequent reduction in striatal dopamine, the pathophysiology of resting tremor remains unclear. |
2002-01-25 |
2023-08-12 |
Not clear |
A B West, A Zimprich, P J Lockhart, M Farrer, A Singleton, B Holtom, S Lincoln, A Hofer, L Hill, B Müller-Myhsok, Z K Wszolek, J Hardy, T Gasse. Refinement of the PARK3 locus on chromosome 2p13 and the analysis of 14 candidate genes. European journal of human genetics : EJHG. vol 9. issue 9. 2001-12-04. PMID:11571553. |
parkinson's disease (pd) is a common neurodegenerative disorder with clinical features of bradykinesia, rigidity, resting tremor and postural instability resulting from the deficiency of dopamine in the nigrostriatal system. |
2001-12-04 |
2023-08-12 |
Not clear |
H Mehta, B Thomas, K P Mohanakuma. Effects of p-chlorophenylalanine on striatal acetylcholinesterase activity and on biogenic amine levels in nuclei raphe and caudate-putamen during physostigmine-induced tremor in rats. Neuroscience letters. vol 299. issue 1-2. 2001-05-03. PMID:11166949. |
peak of physostigmine tremor correlated with increase in 5-ht in nrd and ncp, and a decrease in striatal dopamine (da), as assayed employing high pressure liquid chromotography-electrochemistry. |
2001-05-03 |
2023-08-12 |
rat |
H Reichmann, U Sommer, G Fuchs, H Hefter, G Mark, T Müller, R Thümler, G Ulm, P Vieregg. Workshop IV: drug treatment guidelines for the long-term management of Parkinson's disease. Journal of neurology. vol 247 Suppl 4. 2001-02-15. PMID:11199819. |
in the tremor dominance type we use either budipine or a dopamine agonist. |
2001-02-15 |
2023-08-12 |
Not clear |
G Abrahám, S Sólyom, E Csuzdi, P Berzsenyi, I Ling, I Tarnawa, T Hámori, I Pallagi, K Horváth, F Andrási, G Kapus, L G Hársing, I Király, M Patthy, G Horvát. New non competitive AMPA antagonists. Bioorganic & medicinal chemistry. vol 8. issue 8. 2001-02-01. PMID:11003158. |
3b also reversed the dopamine depleting effect of mptp and antagonized the oxotremorine induced tremor in mice indicating a potential antiparkinson activity. |
2001-02-01 |
2023-08-12 |
mouse |
H T Benamer, J Patterson, D J Wyper, D M Hadley, G J Macphee, D G Grosse. Correlation of Parkinson's disease severity and duration with 123I-FP-CIT SPECT striatal uptake. Movement disorders : official journal of the Movement Disorder Society. vol 15. issue 4. 2001-01-11. PMID:10928580. |
correlation with bradykinesia but not with tremor may indicate an origin for tremor outwith the dopamine transporter system. |
2001-01-11 |
2023-08-12 |
Not clear |
Y H Weng, P F Kao, C H Tsai, T C Yen, C S L. Dopamine deficiency in rubral tremor caused by midbrain hemangioma: case report. Chang Gung medical journal. vol 23. issue 8. 2000-11-03. PMID:11039251. |
dopamine deficiency in rubral tremor caused by midbrain hemangioma: case report. |
2000-11-03 |
2023-08-12 |
Not clear |
Y H Weng, P F Kao, C H Tsai, T C Yen, C S L. Dopamine deficiency in rubral tremor caused by midbrain hemangioma: case report. Chang Gung medical journal. vol 23. issue 8. 2000-11-03. PMID:11039251. |
we concluded that the rubral tremor in the right extremities was probably caused by a dopamine deficiency in the left nigrostriatal system. |
2000-11-03 |
2023-08-12 |
Not clear |
Y H Weng, P F Kao, C H Tsai, T C Yen, C S L. Dopamine deficiency in rubral tremor caused by midbrain hemangioma: case report. Chang Gung medical journal. vol 23. issue 8. 2000-11-03. PMID:11039251. |
this suggests that a dopamine deficiency secondary to the midbrain hemangioma might have contributed to the development of the rubral tremor in this patient. |
2000-11-03 |
2023-08-12 |
Not clear |
J Marjama-Lyons, W Kolle. Tremor-predominant Parkinson's disease. Approaches to treatment. Drugs & aging. vol 16. issue 4. 2000-10-30. PMID:10874522. |
some of the first line medications (levodopa, dopamine agonists, anticholinergics) are very effective in controlling tremor. |
2000-10-30 |
2023-08-12 |
Not clear |
J L Eberling, P Pivirotto, J Bringas, K S Bankiewic. Tremor is associated with PET measures of nigrostriatal dopamine function in MPTP-lesioned monkeys. Experimental neurology. vol 165. issue 2. 2000-10-26. PMID:10993693. |
tremor is associated with pet measures of nigrostriatal dopamine function in mptp-lesioned monkeys. |
2000-10-26 |
2023-08-12 |
monkey |
H Miwa, Y Sasaki, K Hatori, S Tanaka, Y Mizun. [Idiopathic rabbit syndrome: a case report]. No to shinkei = Brain and nerve. vol 51. issue 10. 1999-12-21. PMID:10553594. |
the efficacy of the dopamine blockade may suggest that an abnormal basal ganglia function contributes to the pathophysiologic mechanism underlying this type of tremor. |
1999-12-21 |
2023-08-12 |
rabbit |