| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Paul S Fishma. Paradoxical aspects of parkinsonian tremor. Movement disorders : official journal of the Movement Disorder Society. vol 23. issue 2. 2008-05-08. PMID:17973325. |
patients with only resting tremor show dopaminergic deficits with radioligand imaging, but severity of tremor correlates poorly in such dopamine imaging studies. |
2008-05-08 |
2023-08-12 |
Not clear |
| P Plaha, S Filipovic, S S Gil. Induction of parkinsonian resting tremor by stimulation of the caudal zona incerta nucleus: a clinical study. Journal of neurology, neurosurgery, and psychiatry. vol 79. issue 5. 2008-04-29. PMID:18037629. |
we hypothesise that parkinsonian tremor arises when the caudal zona incerta (czi) and subthalamic nucleus (stn) are deprived of dopamine and become increasingly responsive to motor cortical alpha and beta frequency oscillations. |
2008-04-29 |
2023-08-12 |
Not clear |
| Anthony H V Schapir. Future directions in the treatment of Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 22 Suppl 17. 2008-02-20. PMID:18175401. |
dopaminergic therapies in the form of levodopa, dopamine agonists, or monoamine oxidase b inhibitors significantly improve the characteristic motor symptoms of bradykinesia and rigidity, with a beneficial effect upon tremor in a proportion of patients. |
2008-02-20 |
2023-08-12 |
Not clear |
| John M Burkhardt, Christos Constantinidis, Kristin K Anstrom, David C S Roberts, Donald J Woodwar. Synchronous oscillations and phase reorganization in the basal ganglia during akinesia induced by high-dose haloperidol. The European journal of neuroscience. vol 26. issue 7. 2008-01-29. PMID:17897397. |
movement disorders such as tremor and akinesia observed in parkinson's disease have been attributed to dopamine (da) depletion in the basal ganglia. |
2008-01-29 |
2023-08-12 |
rat |
| Ioannis U Isaias, Riccardo Benti, Roberto Cilia, Margherita Canesi, Giorgio Marotta, Paolo Gerundini, Gianni Pezzoli, Angelo Antonin. [123I]FP-CIT striatal binding in early Parkinson's disease patients with tremor vs. akinetic-rigid onset. Neuroreport. vol 18. issue 14. 2007-12-06. PMID:17712282. |
we performed [123i]fp-cit/spect in 20 drug-naive parkinson's disease (pd) patients, 10 with unilateral akinesia/rigidity at onset (arpd) and 10 with additional tremor-at-rest (tpd), to evaluate whether resting tremor at onset is associated with differences in striatal dopamine transporter binding. |
2007-12-06 |
2023-08-12 |
human |
| Yuji Nagai, Shigeru Obayashi, Kiyoshi Ando, Motoki Inaji, Jun Maeda, Takashi Okauchi, Hiroshi Ito, Tetsuya Suhar. Progressive changes of pre- and post-synaptic dopaminergic biomarkers in conscious MPTP-treated cynomolgus monkeys measured by positron emission tomography. Synapse (New York, N.Y.). vol 61. issue 10. 2007-10-31. PMID:17598150. |
in this study, we aimed to investigate the threshold of dopamine (da) neuron damage for the appearance of tremor by observing the longitudinal changes of pre- and post-synaptic da biomarkers in awake monkeys using pet with multiple tracers. |
2007-10-31 |
2023-08-12 |
monkey |
| Theresa A Zesiewicz, Kelly L Sullivan, Robert A Hause. Levodopa-induced dyskinesia in Parkinson's disease: epidemiology, etiology, and treatment. Current neurology and neuroscience reports. vol 7. issue 4. 2007-09-04. PMID:17618536. |
dyskinesia refers to involuntary movements other than tremor and most commonly consists of chorea that occurs when levodopa-derived dopamine is peaking in the brain ("peak-dose dyskinesia"). |
2007-09-04 |
2023-08-12 |
Not clear |
| K Strecker, J P Schneider, O Sabri, F Wegner, F Then Bergh, J Schwarz, S Hess. Responsiveness to a dopamine agent in Holmes tremor--case report. European journal of neurology. vol 14. issue 4. 2007-06-13. PMID:17388980. |
responsiveness to a dopamine agent in holmes tremor--case report. |
2007-06-13 |
2023-08-12 |
Not clear |
| Hideto Miw. Rodent models of tremor. Cerebellum (London, England). vol 6. issue 1. 2007-05-04. PMID:17366267. |
on the other hand, dopaminergic neurotoxins, which are used in models of parkinsonism, have yet to be used for experimental analysis of tremor, because tremors induced by dopamine depletion in rodents are less remarkable than those induced by harmaline or cholinomimetics. |
2007-05-04 |
2023-08-12 |
mouse |
| J Raethjen, G Deusch. [Tremor]. Therapeutische Umschau. Revue therapeutique. vol 64. issue 1. 2007-03-15. PMID:17221823. |
classical rest tremors are improved by dopaminergic substances (levodopa, dopamine agonists) or anticholinergics. |
2007-03-15 |
2023-08-12 |
Not clear |
| Michael J Fran. Hold your horses: a dynamic computational role for the subthalamic nucleus in decision making. Neural networks : the official journal of the International Neural Network Society. vol 19. issue 8. 2006-12-12. PMID:16945502. |
simulated dopamine depletion results in emergent oscillatory activity in bg structures, which has been linked with parkinson's tremor. |
2006-12-12 |
2023-08-12 |
human |
| R M Miller, L L Chen, G L Kiser, T L Giesler, T M Kaysser-Kranich, C Palaniappan, H J Federof. Temporal evolution of mouse striatal gene expression following MPTP injury. Neurobiology of aging. vol 26. issue 5. 2005-05-09. PMID:15708451. |
the gradual loss of striatal dopamine and dopaminergic neurons residing in the substantia nigra (sn) causes parkinsonism characterized by slow, halting movements, rigidity, and resting tremor when neuronal loss exceeds a threshold of approximately 80%. |
2005-05-09 |
2023-08-12 |
mouse |
| Scott T Grafto. Contributions of functional imaging to understanding parkinsonian symptoms. Current opinion in neurobiology. vol 14. issue 6. 2005-03-23. PMID:15582373. |
parkinson's disease tremor is localized to pontine- and mesencephalic-cerebellar-thalamic circuits, with abnormalities of both dopamine and serotonin neurotransmission. |
2005-03-23 |
2023-08-12 |
Not clear |
| Paul J Lockhart, Mary Hulihan, Sarah Lincoln, Jennifer Hussey, Lisa Skipper, Gina Bisceglio, Kristen Wilkes, Matthew J Farre. Identification of the human ubiquitin specific protease 31 (USP31) gene: structure, sequence and expression analysis. DNA sequence : the journal of DNA sequencing and mapping. vol 15. issue 1. 2004-09-28. PMID:15354349. |
parkinson's disease (pd) is a common neurodegenerative disorder with clinical features of bradykinesia, rigidity and resting tremor resulting from the deficiency of dopamine in the nigrostriatal system. |
2004-09-28 |
2023-08-12 |
human |
| G Salazar Tortolero, R Wix Ramos, P Salazar Aladrén, J C Jiménez Leó. [The effectiveness and tolerance of piribedil as adjunct therapy to levodopa in patients with Parkinson's disease: a nine month follow up]. Revista de neurologia. vol 38. issue 8. 2004-07-23. PMID:15122540. |
piribedil is a d2 d3 dopamine agonist, which has been shown to be well tolerated and to improve parkinsonian symptoms, particularly tremor. |
2004-07-23 |
2023-08-12 |
Not clear |
| Vicky Marshall, Donald G Grosse. Role of dopamine transporter imaging in the diagnosis of atypical tremor disorders. Movement disorders : official journal of the Movement Disorder Society. vol 18 Suppl 7. 2004-03-29. PMID:14531042. |
role of dopamine transporter imaging in the diagnosis of atypical tremor disorders. |
2004-03-29 |
2023-08-12 |
Not clear |
| Vicky Marshall, Donald G Grosse. Role of dopamine transporter imaging in the diagnosis of atypical tremor disorders. Movement disorders : official journal of the Movement Disorder Society. vol 18 Suppl 7. 2004-03-29. PMID:14531042. |
in atypical tremor disorders, dat imaging can differentiate between parkinson's disease (pd), where dopamine deficit is demonstrated on dat imaging, and essential tremor, where no dopamine deficit is found. |
2004-03-29 |
2023-08-12 |
Not clear |
| Alexander Storch, Henry A Lester, Bernhard O Boehm, Johannes Schwar. Functional characterization of dopaminergic neurons derived from rodent mesencephalic progenitor cells. Journal of chemical neuroanatomy. vol 26. issue 2. 2004-01-05. PMID:14599663. |
a primary target for neurorestoration is parkinson's disease, characterized by a continuous loss of the dopaminergic neurons in the substantia nigra pars compacta leading to dopamine depletion in the striatum and subsequent clinical symptoms including bradykinesia, rigidity and tremor. |
2004-01-05 |
2023-08-12 |
human |
| M Rodríguez-Arias, M A Aguilar, J Miñarr. The dopamine release inhibitor CGS 10746B blocks conditioned physical signs of morphine withdrawal. Addiction biology. vol 8. issue 2. 2003-11-12. PMID:12850775. |
the results show that dopamine seems to be necessary for the development of conditioned somatic signs of morphine withdrawal, as animals which received cgs 10746b do not present paw tremor or body shakes when they are placed in the environment paired with two previously induced withdrawals. |
2003-11-12 |
2023-08-12 |
Not clear |
| Rodger J Elbl. Tremor and dopamine agonists. Neurology. vol 58. issue 4 Suppl 1. 2003-09-15. PMID:11909986. |
tremor and dopamine agonists. |
2003-09-15 |
2023-08-12 |
Not clear |