| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Guowei Huang, Xiaohong Cao, Xumei Zhang, Hong Chang, Yunxia Yang, Wenp Du, John X Wilso. Effects of soybean isoflavone on the notch signal pathway of the brain in rats with cerebral ischemia. Journal of nutritional science and vitaminology. vol 55. issue 4. 2009-12-15. PMID:19763033. |
the aim of this study was to test the hypothesis that gastric lavage with soybean isoflavone activates the notch signaling pathway and prevents apoptosis in the cerebral cortex during experimental strokes. |
2009-12-15 |
2023-08-12 |
rat |
| L H Siga. Molecular biology and immunology for clinicians, 8 pathogenesis of autoimmunity-apoptosis. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases. vol 5. issue 4. 2009-12-14. PMID:19078396. |
apoptosis has also been proposed as contributing to neuronal destruction in parkinson's disease, alzheimer's disease, and glaucoma and to the late death of neurons near areas of ischemic cell death from stroke. |
2009-12-14 |
2023-08-12 |
mouse |
| Shibani S Mukerji, Riley N Rainey, Jamie L Rhodes, Alison K Hal. Delayed activin A administration attenuates tissue death after transient focal cerebral ischemia and is associated with decreased stress-responsive kinase activation. Journal of neurochemistry. vol 111. issue 5. 2009-12-11. PMID:19780899. |
activation of the stress-responsive kinases p38 and c-jun n-terminal kinase implicated in neuronal apoptosis after stroke was reduced following activin a treatment. |
2009-12-11 |
2023-08-12 |
mouse |
| Wei Wang, Bitao Bu, Minjie Xie, Min Zhang, Zhiyuan Yu, Deding Ta. Neural cell cycle dysregulation and central nervous system diseases. Progress in neurobiology. vol 89. issue 1. 2009-11-02. PMID:19619927. |
neuronal apoptosis is often detected in acute injury to the cns such as stroke and trauma, which are usually related to the blockade of the cell cycle at the g1-s phase. |
2009-11-02 |
2023-08-12 |
Not clear |
| Hiroshi Ued. Prothymosin alpha and cell death mode switch, a novel target for the prevention of cerebral ischemia-induced damage. Pharmacology & therapeutics. vol 123. issue 3. 2009-10-09. PMID:19500618. |
following stroke or traumatic damage, neuronal death via both necrosis and apoptosis causes loss of functions including memory, sensory perception and motor skills. |
2009-10-09 |
2023-08-12 |
Not clear |
| Hiroshi Ued. Prothymosin alpha and cell death mode switch, a novel target for the prevention of cerebral ischemia-induced damage. Pharmacology & therapeutics. vol 123. issue 3. 2009-10-09. PMID:19500618. |
since necrosis has the nature to expand, while apoptosis stops the cell death cascade in the brain, necrosis is considered to be a promising target for rapid treatment for stroke. |
2009-10-09 |
2023-08-12 |
Not clear |
| Tiina Sairanen, Rita Szepesi, Marja-Liisa Karjalainen-Lindsberg, Jani Saksi, Anders Paetau, Perttu J Lindsber. Neuronal caspase-3 and PARP-1 correlate differentially with apoptosis and necrosis in ischemic human stroke. Acta neuropathologica. vol 118. issue 4. 2009-10-08. PMID:19529948. |
neuronal caspase-3 and parp-1 correlate differentially with apoptosis and necrosis in ischemic human stroke. |
2009-10-08 |
2023-08-12 |
human |
| Olaf Hoffmann, Frauke Zipp, Joerg R Webe. Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) in central nervous system inflammation. Journal of molecular medicine (Berlin, Germany). vol 87. issue 8. 2009-09-21. PMID:19449143. |
trail promotes apoptosis of parenchymal cells in ms/eae, hive, ad and stroke through interaction with trail death receptors expressed on these cells. |
2009-09-21 |
2023-08-12 |
Not clear |
| M Fatar, M Stroick, M Griebe, A Alonso, S Kreisel, R Kern, M Hennerici, S Meair. Effect of combined ultrasound and microbubbles treatment in an experimental model of cerebral ischemia. Ultrasound in medicine & biology. vol 34. issue 9. 2009-09-17. PMID:18436368. |
glutamate, pyruvate, lactate and glycerol levels were measured by intracerebral microdialysis before and after stroke induction and after us+mb application (n = 8) for 20 h. after 24 h, brain infarct volume, apoptosis and il-6 and tnf-alpha levels were evaluated. |
2009-09-17 |
2023-08-12 |
rat |
| Nicole Y Tan, Jian-Mei Li, Roland Stocker, Levon M Khachigia. Angiotensin II-inducible smooth muscle cell apoptosis involves the angiotensin II type 2 receptor, GATA-6 activation, and FasL-Fas engagement. Circulation research. vol 105. issue 5. 2009-09-10. PMID:19628789. |
fas ligand (fasl)-mediated smooth muscle cell (smc) apoptosis within the vulnerable plaque may lead to plaque instability and rupture, events that underlie myocardial infarction and stroke. |
2009-09-10 |
2023-08-12 |
Not clear |
| Elif G Sozmen, Arunima Kolekar, Leif A Havton, S Thomas Carmichae. A white matter stroke model in the mouse: axonal damage, progenitor responses and MRI correlates. Journal of neuroscience methods. vol 180. issue 2. 2009-09-08. PMID:19439360. |
immunohistochemical studies indicate that oligodendrocyte apoptosis is maximal at day 1 and apoptotic cells extend away from the stroke core into the peri-infarct white matter. |
2009-09-08 |
2023-08-12 |
mouse |
| Fransisca Indraswari, Peter T H Wong, Elgin Yap, Y K Ng, S Thameem Dhee. Upregulation of Dpysl2 and Spna2 gene expression in the rat brain after ischemic stroke. Neurochemistry international. vol 55. issue 4. 2009-09-02. PMID:19524114. |
therefore, this study was aimed to investigate the temporal expression of dpysl2 and spna2 genes in normal and stroke rat brain and to characterize stroke brains for cell areas, apoptosis, and microglia cells. |
2009-09-02 |
2023-08-12 |
rat |
| Fransisca Indraswari, Peter T H Wong, Elgin Yap, Y K Ng, S Thameem Dhee. Upregulation of Dpysl2 and Spna2 gene expression in the rat brain after ischemic stroke. Neurochemistry international. vol 55. issue 4. 2009-09-02. PMID:19524114. |
characterization of stroke brain for apoptosis and microglia cells showed apoptotic cells and activated microglia, mainly in the infarct core of ipsilateral cortex and striatum of stroke brain. |
2009-09-02 |
2023-08-12 |
rat |
| Marijke De Saint-Hubert, Kristof Prinsen, Luc Mortelmans, Alfons Verbruggen, Felix M Mottagh. Molecular imaging of cell death. Methods (San Diego, Calif.). vol 48. issue 2. 2009-08-27. PMID:19362149. |
in case of acute myocardial infarction (ami) and cerebral stroke the degree of both apoptosis and necrosis is abundant. |
2009-08-27 |
2023-08-12 |
Not clear |
| K Yamagata, S Ichinose, A Miyashita, M Tagam. Protective effects of ebselen, a seleno-organic antioxidant on neurodegeneration induced by hypoxia and reperfusion in stroke-prone spontaneously hypertensive rat. Neuroscience. vol 153. issue 2. 2009-06-29. PMID:18384965. |
ebselen may be effective in the prevention and/or treatment of neurodegenerative diseases associated with excessive apoptosis in patients with stroke. |
2009-06-29 |
2023-08-12 |
rat |
| Mark Slevin, Jerzy Krupinsk. Cyclin-dependent kinase-5 targeting for ischaemic stroke. Current opinion in pharmacology. vol 9. issue 2. 2009-06-23. PMID:18983942. |
cdk5, a serine/threonine kinase is highly expressed in the central nervous system, particularly following ischaemic stroke and its aberrant activation is directly associated with neuronal apoptosis and death. |
2009-06-23 |
2023-08-12 |
Not clear |
| Mike Yuan, Chad Siegel, Zhiyuan Zeng, Jun Li, Fudong Liu, Louise D McCulloug. Sex differences in the response to activation of the poly (ADP-ribose) polymerase pathway after experimental stroke. Experimental neurology. vol 217. issue 1. 2009-05-26. PMID:19268668. |
nuclear translocation of apoptosis inducing factor (aif) was equivalent in wild type males and females after stroke and was unaffected by estrogen exposure. |
2009-05-26 |
2023-08-12 |
mouse |
| Ihsan Solaroglu, Julian Cahill, Tamiji Tsubokawa, Ethem Beskonakli, John H Zhan. Granulocyte colony-stimulating factor protects the brain against experimental stroke via inhibition of apoptosis and inflammation. Neurological research. vol 31. issue 2. 2009-05-04. PMID:19298757. |
granulocyte colony-stimulating factor protects the brain against experimental stroke via inhibition of apoptosis and inflammation. |
2009-05-04 |
2023-08-12 |
rat |
| Jia Jia, Dening Guan, Wenjing Zhu, Nabil J Alkayed, Michael M Wang, Zichun Hua, Yun X. Estrogen inhibits Fas-mediated apoptosis in experimental stroke. Experimental neurology. vol 215. issue 1. 2009-04-08. PMID:18950622. |
estrogen inhibits fas-mediated apoptosis in experimental stroke. |
2009-04-08 |
2023-08-12 |
mouse |
| Mark P Mattson, Marc Gleichmann, Aiwu Chen. Mitochondria in neuroplasticity and neurological disorders. Neuron. vol 60. issue 5. 2009-04-08. PMID:19081372. |
mitochondria-mediated oxidative stress, perturbed ca(2+) homeostasis, and apoptosis may also contribute to the pathogenesis of prominent neurological diseases including alzheimer's, parkinson's, and huntington's diseases; stroke; amyotrophic lateral sclerosis; and psychiatric disorders. |
2009-04-08 |
2023-08-12 |
Not clear |