| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Etheresia Pretorius, Mia-Jeanne Engelbrecht, Wiebren Dui. Thromboembolic ischemic stroke and the presence of necrotic platelets: a scanning electron microscopy investigation. Ultrastructural pathology. vol 36. issue 1. 2012-05-22. PMID:22292733. |
in the current research, the authors investigate whether a changed platelet ultrastructure is visible in thromboembolic stroke and whether it might be visible in platelets as apoptosis or necrosis. |
2012-05-22 |
2023-08-12 |
Not clear |
| Yuanfei Wang, Michael J Cooke, Cindi M Morshead, Molly S Shoiche. Hydrogel delivery of erythropoietin to the brain for endogenous stem cell stimulation after stroke injury. Biomaterials. vol 33. issue 9. 2012-05-14. PMID:22217804. |
erythropoietin delivered from hamc at 4 and 11 days post-stroke resulted in attenuated inflammatory response, reduced stroke cavity size, increased number of both neurons in the peri-infarct region and migratory neuroblasts in the subventricular zone, and decreased apoptosis in both the subventricular zone and the injured cortex. |
2012-05-14 |
2023-08-12 |
mouse |
| Youhua Xu, Liang Feng, Shanshan Wang, Quan Zhu, Jing Lin, Chihan Lou, Ping Xiang, Bao He, Zhaoguang Zheng, Dan Tang, Guoying Zu. Phytoestrogen calycosin-7-O-β-D-glucopyranoside ameliorates advanced glycation end products-induced HUVEC damage. Journal of cellular biochemistry. vol 112. issue 10. 2012-04-12. PMID:21647942. |
vasculopathy including endothelial cell (ec) apoptosis and inflammation contributes to the high incidence of stroke and myocardial infarction in diabetic patients. |
2012-04-12 |
2023-08-12 |
Not clear |
| Yuming Zhao, Juan Dou, Jialie Luo, Wenming Li, Hugh H N Chan, Wei Cui, Huan Zhang, Renwen Han, Paul R Carlier, Xuejun Zhang, Yifan Ha. Neuroprotection against excitotoxic and ischemic insults by bis(12)-hupyridone, a novel anti-acetylcholinesterase dimer, possibly via acting on multiple targets. Brain research. vol 1421. 2012-02-07. PMID:21978549. |
significantly attenuated ischemia-induced apoptosis in the penumbra region, improved neurological behavior impairment, and decreased cerebral infarct volume, cerebral edema and neuronal apoptosis in the stroke model. |
2012-02-07 |
2023-08-12 |
rat |
| Mark Magharious, Philippe M D'Onofrio, Adam Hollander, Peihong Zhu, Jian Chen, Paulo D Koeberl. Quantitative iTRAQ analysis of retinal ganglion cell degeneration after optic nerve crush. Journal of proteome research. vol 10. issue 8. 2012-01-03. PMID:21627321. |
neuronal apoptosis is also a salient feature of cns trauma, ischemia (stroke), and diseases of the cns such as alzheimer's, parkinson's, multiple sclerosis, and amyotrophic lateral sclerosis. |
2012-01-03 |
2023-08-12 |
rat |
| Preeti Sahota, Sean I Savit. Investigational therapies for ischemic stroke: neuroprotection and neurorecovery. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 8. issue 3. 2011-11-29. PMID:21604061. |
the pathophysiology of stroke is complex and it involves excitotoxicity mechanisms, inflammatory pathways, oxidative damage, ionic imbalances, apoptosis, angiogenesis, neuroprotection, and neurorestoration. |
2011-11-29 |
2023-08-12 |
Not clear |
| Huong T Le, Aaron C Hirko, Jeffrey S Thinschmidt, Maria Grant, Zhimin Li, Joanna Peris, Michael A King, Jeffrey A Hughes, Sihong Son. The protective effects of plasma gelsolin on stroke outcome in rats. Experimental & translational stroke medicine. vol 3. issue 1. 2011-11-23. PMID:22047744. |
excitotoxicity, inflammation and apoptosis are all involved in delayed neuronal death following stroke and offer multiple opportunities to intervene with neuroprotective agents. |
2011-11-23 |
2023-08-12 |
rat |
| Yan Li, Lan Shen, Lei Cai, Qiang Wang, Wugang Hou, Feng Wang, Yi Zeng, Gang Zhao, Libo Yao, Lize Xion. Spatial-temporal expression of NDRG2 in rat brain after focal cerebral ischemia and reperfusion. Brain research. vol 1382. 2011-11-15. PMID:21241684. |
ndrg2 expression in astrocytes may play important pathological roles in cell apoptosis after stroke. |
2011-11-15 |
2023-08-12 |
rat |
| Tommy Seaborn, Olfa Masmoudi-Kouli, Alain Fournier, Hubert Vaudry, David Vaudr. Protective effects of pituitary adenylate cyclase-activating polypeptide (PACAP) against apoptosis. Current pharmaceutical design. vol 17. issue 3. 2011-09-29. PMID:21348830. |
apoptosis is a regulated process leading to cell death, which is implicated both in normal development and in various pathologies including heart failure, stroke and neurodegenerative diseases. |
2011-09-29 |
2023-08-12 |
Not clear |
| Cletus Cheyuo, Rongqian Wu, Mian Zhou, Asha Jacob, Gene Coppa, Ping Wan. Ghrelin suppresses inflammation and neuronal nitric oxide synthase in focal cerebral ischemia via the vagus nerve. Shock (Augusta, Ga.). vol 35. issue 3. 2011-08-04. PMID:20720512. |
the pathogenesis of stroke involves inflammation, apoptosis, and excitotoxicity, which is mediated in part by neuronal no synthase (nnos) activation. |
2011-08-04 |
2023-08-12 |
human |
| Prabal Deb, Suash Sharma, K M Hassa. Pathophysiologic mechanisms of acute ischemic stroke: An overview with emphasis on therapeutic significance beyond thrombolysis. Pathophysiology : the official journal of the International Society for Pathophysiology. vol 17. issue 3. 2011-07-14. PMID:20074922. |
the pathophysiology of stroke is complex, and involves excitotoxicity mechanisms, inflammatory pathways, oxidative damage, ionic imbalances, apoptosis, angiogenesis and neuroprotection. |
2011-07-14 |
2023-08-12 |
Not clear |
| Vijay Sharma, Arpeeta Sharma, Varun Saran, Pascal N Bernatchez, Michael F Allard, John H McNeil. β-receptor antagonist treatment prevents activation of cell death signaling in the diabetic heart independent of its metabolic actions. European journal of pharmacology. vol 657. issue 1-3. 2011-07-06. PMID:21296063. |
metoprolol improved stroke volume and cardiac output, associated with attenuation of tunel staining and a more modest attenuation of caspase-3; however, the positive tunel staining was not associated with an increase in apoptosis or cell regeneration markers. |
2011-07-06 |
2023-08-12 |
rat |
| Cletus Cheyuo, Asha Jacob, Rongqian Wu, Mian Zhou, Gene F Coppa, Ping Wan. The parasympathetic nervous system in the quest for stroke therapeutics. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 31. issue 5. 2011-06-28. PMID:21364605. |
the pathogenesis of stroke involves complex interrelated molecular mechanisms including excitotoxicity, oxidative and nitrosative stress, cortical spreading depolarizations, inflammation, necrosis, and apoptosis. |
2011-06-28 |
2023-08-12 |
Not clear |
| Jun Xiang, Yu-Ping Tang, Ping Wu, Jun-Peng Gao, Ding-Fang Ca. Chinese medicine Nao-Shuan-Tong attenuates cerebral ischemic injury by inhibiting apoptosis in a rat model of stroke. Journal of ethnopharmacology. vol 131. issue 1. 2011-05-27. PMID:20600767. |
chinese medicine nao-shuan-tong attenuates cerebral ischemic injury by inhibiting apoptosis in a rat model of stroke. |
2011-05-27 |
2023-08-12 |
rat |
| Jose C Gomez-Sanchez, Maria Delgado-Esteban, Irene Rodriguez-Hernandez, Tomas Sobrino, Natalia Perez de la Ossa, Silvia Reverte, Juan P Bolaños, Rogelio Gonzalez-Sarmiento, Jose Castillo, Angeles Almeid. The human Tp53 Arg72Pro polymorphism explains different functional prognosis in stroke. The Journal of experimental medicine. vol 208. issue 3. 2011-05-24. PMID:21357744. |
the presence of apoptotic neurons in the ischemic penumbra and perihematoma area may account for poor prognosis, but whether the highly variable stroke outcome reflects differences in genetic susceptibility to apoptosis is elusive. |
2011-05-24 |
2023-08-12 |
human |
| Jose C Gomez-Sanchez, Maria Delgado-Esteban, Irene Rodriguez-Hernandez, Tomas Sobrino, Natalia Perez de la Ossa, Silvia Reverte, Juan P Bolaños, Rogelio Gonzalez-Sarmiento, Jose Castillo, Angeles Almeid. The human Tp53 Arg72Pro polymorphism explains different functional prognosis in stroke. The Journal of experimental medicine. vol 208. issue 3. 2011-05-24. PMID:21357744. |
these results suggest that the tp53 arg/arg genotype governs neuronal vulnerability to apoptosis and can be considered as a genetic marker predicting poor functional outcome after stroke. |
2011-05-24 |
2023-08-12 |
human |
| Xinjie Bao, Junji Wei, Ming Feng, Shan Lu, Guilin Li, Wanchen Dou, Wenbin Ma, Sihai Ma, Yihua An, Chuan Qin, Robert Chunhua Zhao, Renzhi Wan. Transplantation of human bone marrow-derived mesenchymal stem cells promotes behavioral recovery and endogenous neurogenesis after cerebral ischemia in rats. Brain research. vol 1367. 2011-04-15. PMID:20977892. |
endogenous cell proliferation in the subventricular zone (svz) after stroke is well known, but most of newly formed cells underwent apoptosis. |
2011-04-15 |
2023-08-12 |
human |
| Nai-Wen Tsai, Wen-Neng Chang, Chen-Fu Shaw, Chung-Ren Jan, Cheng-Hsien L. Leucocyte apoptosis in patients with acute ischaemic stroke. Clinical and experimental pharmacology & physiology. vol 37. issue 9. 2011-02-04. PMID:20456424. |
leucocyte apoptosis in patients with acute ischaemic stroke. |
2011-02-04 |
2023-08-12 |
Not clear |
| Nai-Wen Tsai, Wen-Neng Chang, Chen-Fu Shaw, Chung-Ren Jan, Cheng-Hsien L. Leucocyte apoptosis in patients with acute ischaemic stroke. Clinical and experimental pharmacology & physiology. vol 37. issue 9. 2011-02-04. PMID:20456424. |
little is known about the correlation between leucocyte apoptosis and acute ischaemic stroke (ais). |
2011-02-04 |
2023-08-12 |
Not clear |
| Nai-Wen Tsai, Wen-Neng Chang, Chen-Fu Shaw, Chung-Ren Jan, Cheng-Hsien L. Leucocyte apoptosis in patients with acute ischaemic stroke. Clinical and experimental pharmacology & physiology. vol 37. issue 9. 2011-02-04. PMID:20456424. |
leucocyte apoptosis and the apoptosis of leucocyte subsets were significantly lower in stroke patients than in the control group (p < 0.01). |
2011-02-04 |
2023-08-12 |
Not clear |