| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Hughes, D Young, M Draguno. MK-801 sensitizes rats to pilocarpine induced limbic seizures and status epilepticus. Neuroreport. vol 4. issue 3. 1993-05-21. PMID:8477054. |
mk-801 sensitizes rats to pilocarpine induced limbic seizures and status epilepticus. |
1993-05-21 |
2023-08-12 |
rat |
| C G Wasterlain, C F Baxter, R A Baldwi. GABA metabolism in the substantia nigra, cortex, and hippocampus during status epilepticus. Neurochemical research. vol 18. issue 4. 1993-05-19. PMID:8474571. |
the metabolism of gaba and other amino acids was studied in the substantia nigra, the hippocampus and the parietal cortex of rats following microinjections of gamma-vinyl-gaba during status epilepticus induced by lithium and pilocarpine. |
1993-05-19 |
2023-08-12 |
rat |
| C J Peterson, S Vinayak, A Pazos, K Gal. A rodent model of focally evoked self-sustaining status epilepticus. European journal of pharmacology. vol 221. issue 1. 1993-01-13. PMID:1459187. |
pilocarpine (25 mg/kg) pretreatment also predisposed to status epilepticus in response to the focal application of bicuculline, but diazepam (5 or 10 mg/kg i.p.) |
1993-01-13 |
2023-08-11 |
rat |
| C J Peterson, S Vinayak, A Pazos, K Gal. A rodent model of focally evoked self-sustaining status epilepticus. European journal of pharmacology. vol 221. issue 1. 1993-01-13. PMID:1459187. |
was ineffective in suppressing the status epilepticus in the presence of pilocarpine. |
1993-01-13 |
2023-08-11 |
rat |
| R S Jope, K Kolasa, L Song, G C Ormand. Seizures selectively impair agonist-stimulated phosphoinositide hydrolysis without affecting protein kinase C activity in rat brain. Neurotoxicology. vol 13. issue 2. 1992-12-17. PMID:1331919. |
the influence of seizures on phosphoinositide hydrolysis and protein kinase c activity was measured in rat hippocampus and cerebral cortex, primarily using a model in which generalized convulsive status epilepticus was induced by administration of licl (3 mmole/kg) 20 hr prior to pilocarpine (30 mg/kg). |
1992-12-17 |
2023-08-11 |
rat |
| E Hirsch, T Z Baram, O C Snea. Ontogenic study of lithium-pilocarpine-induced status epilepticus in rats. Brain research. vol 583. issue 1-2. 1992-09-18. PMID:1324090. |
lithium is known to potentiate the ability of pilocarpine to induce status epilepticus in rats. |
1992-09-18 |
2023-08-11 |
rat |
| E Hirsch, T Z Baram, O C Snea. Ontogenic study of lithium-pilocarpine-induced status epilepticus in rats. Brain research. vol 583. issue 1-2. 1992-09-18. PMID:1324090. |
in the 7-10-day-old animals pretreatment with lithium and pilocarpine 60 mg/kg induced status epilepticus with sustained myoclonus and continuous bilateral synchronous spike and sharp wave, but doses of pilocarpine lower than 60 mg/kg had no effect. |
1992-09-18 |
2023-08-11 |
rat |
| E Hirsch, T Z Baram, O C Snea. Ontogenic study of lithium-pilocarpine-induced status epilepticus in rats. Brain research. vol 583. issue 1-2. 1992-09-18. PMID:1324090. |
during this time period, rats treated with lithium (3 meq/kg) plus pilocarpine 10 mg/kg exhibited behavioral and eeg manifestations of status epilepticus. |
1992-09-18 |
2023-08-11 |
rat |
| E Hirsch, T Z Baram, O C Snea. Ontogenic study of lithium-pilocarpine-induced status epilepticus in rats. Brain research. vol 583. issue 1-2. 1992-09-18. PMID:1324090. |
the same combination of lithium and pilocarpine failed to induce status epilepticus either before or after the third week of life. |
1992-09-18 |
2023-08-11 |
rat |
| R S Jope, X G. Seizures increase acetylcholine and choline concentrations in rat brain regions. Neurochemical research. vol 16. issue 11. 1992-06-22. PMID:1815138. |
status epilepticus induced by (i) coadministration of lithium and pilocarpine caused massive increases in the concentration of acetylcholine in the cerebral cortex and hippocampus, (ii) a high dose of pilocarpine did not cause an increase of acetylcholine, and (iii) kainate increased acetylcholine, but the magnitude was lower than with the lithium/pilocarpine model. |
1992-06-22 |
2023-08-11 |
rat |
| R S Jope, X G. Seizures increase acetylcholine and choline concentrations in rat brain regions. Neurochemical research. vol 16. issue 11. 1992-06-22. PMID:1815138. |
the excessive acetylcholine present during status epilepticus induced by lithium and pilocarpine was responsive to pharmacological manipulation. |
1992-06-22 |
2023-08-11 |
rat |
| R Schmidt-Kastner, C Heim, K H Sonta. Damage of substantia nigra pars reticulata during pilocarpine-induced status epilepticus in the rat: immunohistochemical study of neurons, astrocytes and serum-protein extravasation. Experimental brain research. vol 86. issue 1. 1992-01-31. PMID:1756784. |
in this study, status epilepticus was induced by systemic injection of pilocarpine in rats. |
1992-01-31 |
2023-08-11 |
rat |
| N Y Walton, D M Treima. Motor and electroencephalographic response of refractory experimental status epilepticus in rats to treatment with MK-801, diazepam, or MK-801 plus diazepam. Brain research. vol 553. issue 1. 1991-12-24. PMID:1933279. |
in this experiment, rats in status epilepticus induced by lithium and pilocarpine were treated with mk-801 alone, diazepam alone or mk-801 plus diazepam, with treatment begun at a time when this model of status is refractory to anticonvulsant drugs. |
1991-12-24 |
2023-08-11 |
human |
| K Yamada, M D Saltarelli, J T Coyl. [3H]hemicholinium-3 binding in rats with status epilepticus induced by lithium chloride and pilocarpine. European journal of pharmacology. vol 195. issue 3. 1991-09-17. PMID:1651249. |
[3h]hemicholinium-3 binding in rats with status epilepticus induced by lithium chloride and pilocarpine. |
1991-09-17 |
2023-08-11 |
rat |
| K Yamada, M D Saltarelli, J T Coyl. [3H]hemicholinium-3 binding in rats with status epilepticus induced by lithium chloride and pilocarpine. European journal of pharmacology. vol 195. issue 3. 1991-09-17. PMID:1651249. |
the specific binding of [3h]hemicholinium-3 ([3h]hch-3) and high-affinity [3h]choline uptake were measured in rats with status epilepticus induced by lithium and pilocarpine. |
1991-09-17 |
2023-08-11 |
rat |
| N Y Walton, S Gunawan, D M Treima. Brain amino acid concentration changes during status epilepticus induced by lithium and pilocarpine. Experimental neurology. vol 108. issue 1. 1990-05-10. PMID:1969357. |
brain amino acid concentration changes during status epilepticus induced by lithium and pilocarpine. |
1990-05-10 |
2023-08-11 |
rat |
| N Y Walton, S Gunawan, D M Treima. Brain amino acid concentration changes during status epilepticus induced by lithium and pilocarpine. Experimental neurology. vol 108. issue 1. 1990-05-10. PMID:1969357. |
amino acid concentrations were measured in specific structures from the brains of rats decapitated before and during the course of status epilepticus induced by lithium and pilocarpine, with the stages of status defined by the electroencephalographic (eeg) pattern displayed. |
1990-05-10 |
2023-08-11 |
rat |
| D M Treiman, N Y Walton, C Kendric. A progressive sequence of electroencephalographic changes during generalized convulsive status epilepticus. Epilepsy research. vol 5. issue 1. 1990-03-28. PMID:2303022. |
we confirmed our hypothesis that this sequence represents the natural history of electroencephalographic changes in untreated generalized convulsive status epilepticus by observing the same sequence in the eegs of rats in which status epilepticus had been induced by 3 different methods: (1) systemic administration of kainic acid, (2) injection of homocysteine thiolactone to cobalt-lesioned rats; and (3) injection of lithium chloride followed 24 h later by injection of pilocarpine. |
1990-03-28 |
2023-08-11 |
rat |
| R S Jope, J M Miller, T N Ferraro, T A Har. Chronic lithium treatment and status epilepticus induced by lithium and pilocarpine cause selective changes of amino acid concentrations in rat brain regions. Neurochemical research. vol 14. issue 9. 1990-01-25. PMID:2594148. |
chronic lithium treatment and status epilepticus induced by lithium and pilocarpine cause selective changes of amino acid concentrations in rat brain regions. |
1990-01-25 |
2023-08-11 |
rat |
| R S Jope, J M Miller, T N Ferraro, T A Har. Chronic lithium treatment and status epilepticus induced by lithium and pilocarpine cause selective changes of amino acid concentrations in rat brain regions. Neurochemical research. vol 14. issue 9. 1990-01-25. PMID:2594148. |
we measured the effects of four weeks of dietary lithium treatment and of status epilepticus induced by administration of pilocarpine to lithium-treated rats on the concentrations of amino acids in four regions of rat brain: cerebral cortex, hippocampus, striatum, and substantia nigra. |
1990-01-25 |
2023-08-11 |
rat |