| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P A Rutecki, Y Yan. Ictal epileptiform activity in the CA3 region of hippocampal slices produced by pilocarpine. Journal of neurophysiology. vol 79. issue 6. 1998-07-17. PMID:9636105. |
pilocarpine, a muscarinic agonist, produces status epilepticus that is associated with the later development of chronic recurrent seizures. |
1998-07-17 |
2023-08-12 |
rat |
| A C Rice, R J DeLorenz. NMDA receptor activation during status epilepticus is required for the development of epilepsy. Brain research. vol 782. issue 1-2. 1998-05-14. PMID:9519269. |
the pilocarpine model of limbic epilepsy involves inducing status epilepticus (se) with the subsequent development of spontaneous recurrent seizures (srss) and is widely accepted as a model of limbic epilepsy in humans. |
1998-05-14 |
2023-08-12 |
Not clear |
| C Hamani, L E Mell. Status epilepticus induced by pilocarpine and picrotoxin. Epilepsy research. vol 28. issue 1. 1997-11-28. PMID:9255601. |
status epilepticus induced by pilocarpine and picrotoxin. |
1997-11-28 |
2023-08-12 |
human |
| C Hamani, L E Mell. Status epilepticus induced by pilocarpine and picrotoxin. Epilepsy research. vol 28. issue 1. 1997-11-28. PMID:9255601. |
since its original description over 10 years ago, the pilocarpine model of status epilepticus (se) has gained considerable attention. |
1997-11-28 |
2023-08-12 |
human |
| C Hamani, L E Mell. Status epilepticus induced by pilocarpine and picrotoxin. Epilepsy research. vol 28. issue 1. 1997-11-28. PMID:9255601. |
animals injected with three-specific dose combinations (pilocarpine dose/picrotoxin dose), 150/0.5, 75/1.5 and 50/2.0 mg/kg, evoked status epilepticus (se) within 23, 31 and 27 min, respectively. |
1997-11-28 |
2023-08-12 |
human |
| A K Nagy, N Y Walton, D M Treima. Reduced cortical ecto-ATPase activity in rat brains during prolonged status epilepticus induced by sequential administration of lithium and pilocarpine. Molecular and chemical neuropathology. vol 31. issue 2. 1997-11-07. PMID:9376020. |
reduced cortical ecto-atpase activity in rat brains during prolonged status epilepticus induced by sequential administration of lithium and pilocarpine. |
1997-11-07 |
2023-08-12 |
rat |
| T Lemos, E A Cavalheir. Status epilepticus and the late development of spontaneous seizures in the pilocarpine model of epilepsy. Epilepsy research. Supplement. vol 12. 1997-10-23. PMID:9302512. |
status epilepticus and the late development of spontaneous seizures in the pilocarpine model of epilepsy. |
1997-10-23 |
2023-08-12 |
Not clear |
| R Schmidt-Kastner, M Ingva. Laminar damage of neurons and astrocytes in neocortex and hippocampus of rat after long-lasting status epilepticus induced by pilocarpine. Epilepsy research. Supplement. vol 12. 1997-10-23. PMID:9302530. |
laminar damage of neurons and astrocytes in neocortex and hippocampus of rat after long-lasting status epilepticus induced by pilocarpine. |
1997-10-23 |
2023-08-12 |
rat |
| D Lurton, E A Cavalheir. Neuropeptide-Y immunoreactivity in the pilocarpine model of temporal lobe epilepsy. Experimental brain research. vol 116. issue 1. 1997-10-23. PMID:9305828. |
the pilocarpine (pilo) model of epilepsy is characterized by an acute period of status epilepticus followed by spontaneous recurrent seizures and related brain damage. |
1997-10-23 |
2023-08-12 |
Not clear |
| U Sayin, P A Ruteck. Effects of pilocarpine on paired pulse inhibition in the CA3 region of the rat hippocampus. Brain research. vol 758. issue 1-2. 1997-09-16. PMID:9203542. |
pilocarpine (pilo), a muscarinic agonist, produces status epilepticus when administered to rats in vivo and induces interictal or ictal patterns of epileptiform activity in rat hippocampal slices. |
1997-09-16 |
2023-08-12 |
rat |
| K Thompson, C Wasterlai. Lithium-pilocarpine status epilepticus in the immature rabbit. Brain research. Developmental brain research. vol 100. issue 1. 1997-07-24. PMID:9174239. |
we have developed a new model of status epilepticus using systemically injected pilocarpine in immature rabbits pretreated with lithium. |
1997-07-24 |
2023-08-12 |
rabbit |
| M G Lee, J Y Chou, K H Lee, B J Choi, S K Kim, C Y Ki. MK-801 augments pilocarpine-induced electrographic seizure but protects against brain damage in rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 21. issue 2. 1997-06-05. PMID:9061777. |
these results indicate that status epilepticus induced by pilocarpine is initiated by cholinergic overstimulation and propagated by glutamatergic transmission, the elevation of which may cause brain damage through an excitatory nmda receptor-mediated mechanism. |
1997-06-05 |
2023-08-12 |
rat |
| T G Kokate, A L Cohen, E Karp, M A Rogawsk. Neuroactive steroids protect against pilocarpine- and kainic acid-induced limbic seizures and status epilepticus in mice. Neuropharmacology. vol 35. issue 8. 1997-04-23. PMID:9121607. |
steroids with the 3-hydroxy group in the alpha-position and 5-h in the alpha- or beta-configurations were highly effective in protecting against pilocarpine (416 mg/kg, s.c.)-induced limbic motor seizures and status epilepticus (ed50 values, 7.0-18.7 mg/kg, i.p.). |
1997-04-23 |
2023-08-12 |
mouse |
| L E Mello, C M Kohman, A M Tan, E A Cavalheiro, D M Finc. Lack of Fos-like immunoreactivity after spontaneous seizures or reinduction of status epilepticus by pilocarpine in rats. Neuroscience letters. vol 208. issue 2. 1997-04-11. PMID:8859908. |
lack of fos-like immunoreactivity after spontaneous seizures or reinduction of status epilepticus by pilocarpine in rats. |
1997-04-11 |
2023-08-12 |
rat |
| L E Mello, C M Kohman, A M Tan, E A Cavalheiro, D M Finc. Lack of Fos-like immunoreactivity after spontaneous seizures or reinduction of status epilepticus by pilocarpine in rats. Neuroscience letters. vol 208. issue 2. 1997-04-11. PMID:8859908. |
acute seizures and status epilepticus induced by pilocarpine lead to the expression of fos-like immunoreactivity in several specific brain areas in a manner similar to that of other models of limbic seizures. |
1997-04-11 |
2023-08-12 |
rat |
| L E Mello, C M Kohman, A M Tan, E A Cavalheiro, D M Finc. Lack of Fos-like immunoreactivity after spontaneous seizures or reinduction of status epilepticus by pilocarpine in rats. Neuroscience letters. vol 208. issue 2. 1997-04-11. PMID:8859908. |
upon development of status epilepticus after systemic pilocarpine injection, animals develop a state where chronic spontaneous seizures recur. |
1997-04-11 |
2023-08-12 |
rat |
| N Belluardo, G Mudo, X H Jiang, D F Condorell. Induction of astroglial gene expression by experimental seizures in the rat: spatio-temporal patterns of the early stages. Glia. vol 16. issue 2. 1997-03-19. PMID:8929904. |
two different models of status epilepticus were studied: one is produced by the administration of pilocarpine to lithium-treated rats and the other by the intracerebroventricular administration of kainate. |
1997-03-19 |
2023-08-12 |
rat |
| A M Alam, M S Star. Regional changes in brain dopamine utilization during status epilepticus in the rat induced by systemic pilocarpine and intrahippocampal carbachol. Neuropharmacology. vol 35. issue 2. 1997-03-05. PMID:8734484. |
regional changes in brain dopamine utilization during status epilepticus in the rat induced by systemic pilocarpine and intrahippocampal carbachol. |
1997-03-05 |
2023-08-12 |
rat |
| M J Fernandes, M G Naffah-Mazzacoratti, E A Cavalheir. Na+K+ ATPase activity in the rat hippocampus: a study in the pilocarpine model of epilepsy. Neurochemistry international. vol 28. issue 5-6. 1996-12-30. PMID:8792330. |
systemic administration of pilocarpine in rats induces electrographic and behavioral limbic seizures and status epilepticus, that is followed by a transient seizure-free period (silent period). |
1996-12-30 |
2023-08-12 |
rat |
| M J Fernandes, M G Naffah-Mazzacoratti, E A Cavalheir. Na+K+ ATPase activity in the rat hippocampus: a study in the pilocarpine model of epilepsy. Neurochemistry international. vol 28. issue 5-6. 1996-12-30. PMID:8792330. |
the enzyme activity was determined at different time points from pilocarpine administration (1 and 24 h of status epilepticus, during the silent and chronic period) using a spectrophotometric assay previously described by mishra and delivoria-papadopoulos [neurochem. |
1996-12-30 |
2023-08-12 |
rat |