| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B George, S K Kulkarn. Protective effects of GABAergic drugs and other anticonvulsants in lithium-pilocarpine-induced status epilepticus. Methods and findings in experimental and clinical pharmacology. vol 18. issue 5. 1996-11-27. PMID:8817469. |
the symptoms of status epilepticus (se) developed within 26.8 +/- 3.6 min after administering pilocarpine and these symptoms continued uninterrupted. |
1996-11-27 |
2023-08-12 |
rat |
| R Schmidt-Kastner, C Humpel, C Wetmore, L Olso. Cellular hybridization for BDNF, trkB, and NGF mRNAs and BDNF-immunoreactivity in rat forebrain after pilocarpine-induced status epilepticus. Experimental brain research. vol 107. issue 3. 1996-10-30. PMID:8821376. |
in this study, a high dose of pilocarpine (300 mg/kg) was used to induce long-lasting, limbic motor status epilepticus and a selective pattern of brain damage. |
1996-10-30 |
2023-08-12 |
rat |
| R Schmidt-Kastner, C Humpel, C Wetmore, L Olso. Cellular hybridization for BDNF, trkB, and NGF mRNAs and BDNF-immunoreactivity in rat forebrain after pilocarpine-induced status epilepticus. Experimental brain research. vol 107. issue 3. 1996-10-30. PMID:8821376. |
endogenous neurotrophins are upregulated during status epilepticus caused by pilocarpine, which is related to the coupling between neuronal excitation and trophic factor expression. |
1996-10-30 |
2023-08-12 |
rat |
| R Köhling, A Lücke, T Nagao, E J Speckmann, M Avol. Extracellular potassium elevations in the hippocampus of rats with long-term pilocarpine seizures. Neuroscience letters. vol 201. issue 1. 1996-10-16. PMID:8830321. |
pilocarpine injection into rodents leads to the development of chronic limbic seizures that follow an initial status epilepticus and a seizure-free interval. |
1996-10-16 |
2023-08-12 |
rat |
| G Mudò, X H Jiang, T Timmusk, M Bindoni, N Belluard. Change in neurotrophins and their receptor mRNAs in the rat forebrain after status epilepticus induced by pilocarpine. Epilepsia. vol 37. issue 2. 1996-07-09. PMID:8635431. |
change in neurotrophins and their receptor mrnas in the rat forebrain after status epilepticus induced by pilocarpine. |
1996-07-09 |
2023-08-12 |
rat |
| M G Naffah-Mazzacoratti, M I Bellíssimo, E A Cavalheir. Profile of prostaglandin levels in the rat hippocampus in pilocarpine model of epilepsy. Neurochemistry international. vol 27. issue 6. 1996-03-08. PMID:8574174. |
pilocarpine (pilo) administered to rats acutely induces status epilepticus (acute period), which is followed by a transient seizure-free period (silent period), and finally by a chronic phase of spontaneous recurrent seizures (chronic period, srs) that lasts for the rest of animal's life. |
1996-03-08 |
2023-08-12 |
rat |
| R Schmidt-Kastner, L Olso. Decrease of neurotrophin-3 mRNA in adult rat hippocampus after pilocarpine seizures. Experimental neurology. vol 136. issue 2. 1996-01-17. PMID:7498409. |
pilocarpine at a dose of 250 mg/kg induced either limbic seizures (ls) or limbic motor status epilepticus (lmse) in adult rats. |
1996-01-17 |
2023-08-12 |
human |
| E A Cavalheir. The pilocarpine model of epilepsy. Italian journal of neurological sciences. vol 16. issue 1-2. 1995-09-19. PMID:7642349. |
the systemic administration of a potent muscarinic agonist pilocarpine in rats promotes sequential behavioural and electrographic changes that can be divided in three distinct periods: (a) an acute period that built up progressively into a limbic status epilepticus and that lasts 24 h, (b) a silent period with a progressive normalization of eeg and behaviour which varies from 4 to 44 days, and (c) a chronic period with spontaneous recurrent seizures (srss). |
1995-09-19 |
2023-08-12 |
human |
| N Y Walton, B K Rubinstein, D M Treima. Cardiac hypertrophy secondary to status epilepticus in the rat. Epilepsy research. vol 20. issue 2. 1995-06-16. PMID:7750508. |
status epilepticus was induced in rats by sequential injections of lithium and pilocarpine. |
1995-06-16 |
2023-08-12 |
rat |
| J P Leite, E A Cavalheir. Effects of conventional antiepileptic drugs in a model of spontaneous recurrent seizures in rats. Epilepsy research. vol 20. issue 2. 1995-06-16. PMID:7750514. |
pilocarpine (pilo) induces in rats limbic seizures that become secondarily generalized and evolve to status epilepticus (se). |
1995-06-16 |
2023-08-12 |
human |
| R Schmidt-Kastner, A Tomac, B Hoffer, S Bektesh, B Rosenzweig, L Olso. Glial cell-line derived neurotrophic factor (GDNF) mRNA upregulation in striatum and cortical areas after pilocarpine-induced status epilepticus in rats. Brain research. Molecular brain research. vol 26. issue 1-2. 1995-03-16. PMID:7854063. |
using limbic motor status epilepticus induced by pilocarpine to activate neurons in motor and limbic areas, we now demonstrate gdnf mrna signals in the striatum, hippocampus and cortex using in situ hybridisation. |
1995-03-16 |
2023-08-12 |
rat |
| R Schmidt-Kastner, M Ingva. Loss of immunoreactivity for glial fibrillary acidic protein (GFAP) in astrocytes as a marker for profound tissue damage in substantia nigra and basal cortical areas after status epilepticus induced by pilocarpine in rat. Glia. vol 12. issue 3. 1995-03-14. PMID:7851985. |
loss of immunoreactivity for glial fibrillary acidic protein (gfap) in astrocytes as a marker for profound tissue damage in substantia nigra and basal cortical areas after status epilepticus induced by pilocarpine in rat. |
1995-03-14 |
2023-08-12 |
rat |
| R Schmidt-Kastner, M Ingva. Loss of immunoreactivity for glial fibrillary acidic protein (GFAP) in astrocytes as a marker for profound tissue damage in substantia nigra and basal cortical areas after status epilepticus induced by pilocarpine in rat. Glia. vol 12. issue 3. 1995-03-14. PMID:7851985. |
status epilepticus induced by pilocarpine in rats induces massive tissue damage comprising neurons and astrocytes (incomplete infarction) in substantia nigra pars reticulata (snr) and in basal cortical areas (bctx). |
1995-03-14 |
2023-08-12 |
rat |
| P N'gouemo, C Nguemby-Bina, M Baldy-Moulinie. Some neuropharmacological effects of an ethanolic extract of Maprounea africana in rodents. Journal of ethnopharmacology. vol 43. issue 3. 1995-01-09. PMID:7990488. |
however, the extract did not affect either generalized convulsions induced by maximal electroshock and picrotoxin or limbic status epilepticus produced by pilocarpine and kainic acid. |
1995-01-09 |
2023-08-12 |
mouse |
| M B Williams, R S Jop. Distinctive rat brain immediate early gene responses to seizures induced by lithium plus pilocarpine. Brain research. Molecular brain research. vol 25. issue 1-2. 1995-01-05. PMID:7984056. |
the mrna levels of four immediate early genes (ieg) were measured in rat brain regions 60 min after administration of pilocarpine (30 mg/kg) to lithium-treated (3 mmol/kg) rats, during generalized convulsive status epilepticus. |
1995-01-05 |
2023-08-12 |
rat |
| T Nagao, M Avoli, P Gloo. Interictal discharges in the hippocampus of rats with long-term pilocarpine seizures. Neuroscience letters. vol 174. issue 2. 1994-12-29. PMID:7970173. |
systemic administration of pilocarpine to adult rats induces an acute status epilepticus followed by spontaneous recurrent seizures after a 1-2-week silent period. |
1994-12-29 |
2023-08-12 |
human |
| P N'Gouemo, H Pambou-Tchivounda, M Baldy-Moulinier, B Koudogbo, C N'Guemby-Bin. Some pharmacological effects of an ethanolic extract of Trema guineensis on the central nervous system in rodents. Planta medica. vol 60. issue 4. 1994-11-01. PMID:7938262. |
in contrast, t. guineensis did not affect convulsions induced by maximal electroshock and picrotoxin in mice nor status epilepticus produced by pilocarpine and kainic acid in rats. |
1994-11-01 |
2023-08-12 |
mouse |
| T Harrigan, Y R Bureau, M A Persinger, G H Parke. Prevention of sudden cardiac death by the atypical neuroleptic acepromazine following status epilepticus in rats. Life sciences. vol 54. issue 24. 1994-06-27. PMID:8196501. |
normal male rats in which status epilepticus has been induced by injecting 30 mg/kg of pilocarpine after a single systemic administration of lithium (sufficient to produce blood levels of 0.2 meq/l) invariably die within 24 hr. |
1994-06-27 |
2023-08-12 |
rat |
| E A Cavalheiro, M J Fernandes, L Turski, M G Naffah-Mazzacoratt. Spontaneous recurrent seizures in rats: amino acid and monoamine determination in the hippocampus. Epilepsia. vol 35. issue 1. 1994-03-25. PMID:8112229. |
these findings show important neurochemical changes in the course of establishment of an epileptic focus after brain damage induced by status epilepticus triggered by pilocarpine. |
1994-03-25 |
2023-08-12 |
rat |
| P Barone, M Morelli, G Cicarelli, A Cozzolino, G DeJoanna, G Campanella, G DiChiar. Expression of c-fos protein in the experimental epilepsy induced by pilocarpine. Synapse (New York, N.Y.). vol 14. issue 1. 1993-07-15. PMID:8511714. |
generalized seizures, including motor limbic seizures and status epilepticus, were induced by either a convulsant dose of pilocarpine (400 mg/kg) or a low dose of pilocarpine (15-200 mg/kg) combined with either lithium or the d-1 selective agonist skf 38393. |
1993-07-15 |
2023-08-12 |
rat |