| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E J Meyer, I I Kirov, A Tal, M S Davitz, J S Babb, M Lazar, D Malaspina, O Gone. Metabolic Abnormalities in the Hippocampus of Patients with Schizophrenia: A 3D Multivoxel MR Spectroscopic Imaging Study at 3T. AJNR. American journal of neuroradiology. vol 37. issue 12. 2017-09-27. PMID:27444940. |
metabolic abnormalities in the hippocampus of patients with schizophrenia: a 3d multivoxel mr spectroscopic imaging study at 3t. |
2017-09-27 |
2023-08-13 |
Not clear |
| E J Meyer, I I Kirov, A Tal, M S Davitz, J S Babb, M Lazar, D Malaspina, O Gone. Metabolic Abnormalities in the Hippocampus of Patients with Schizophrenia: A 3D Multivoxel MR Spectroscopic Imaging Study at 3T. AJNR. American journal of neuroradiology. vol 37. issue 12. 2017-09-27. PMID:27444940. |
schizophrenia is well-known to be associated with hippocampal structural abnormalities. |
2017-09-27 |
2023-08-13 |
Not clear |
| Joana Viana, Eilis Hannon, Emma Dempster, Ruth Pidsley, Ruby Macdonald, Olivia Knox, Helen Spiers, Claire Troakes, Safa Al-Saraj, Gustavo Turecki, Leonard C Schalkwyk, Jonathan Mil. Schizophrenia-associated methylomic variation: molecular signatures of disease and polygenic risk burden across multiple brain regions. Human molecular genetics. vol 26. issue 1. 2017-09-26. PMID:28011714. |
genome-wide dna methylation was quantified in 262 post-mortem brain samples, representing tissue from four brain regions (prefrontal cortex, striatum, hippocampus and cerebellum) from 41 schizophrenia patients and 47 controls. |
2017-09-26 |
2023-08-13 |
Not clear |
| Gregory V Carr, Jingshan Chen, Feng Yang, Ming Ren, Peixiong Yuan, Qingjun Tian, Audrey Bebensee, Grace Y Zhang, Jing Du, Paul Glineburg, Randy Xun, Omoye Akhile, Daniel Akuma, James Pickel, James C Barrow, Francesco Papaleo, Daniel R Weinberge. KCNH2-3.1 expression impairs cognition and alters neuronal function in a model of molecular pathology associated with schizophrenia. Molecular psychiatry. vol 21. issue 11. 2017-09-19. PMID:26857598. |
however, they show alterations in neuronal structure and microcircuit function in the hippocampus and prefrontal cortex, areas affected in schizophrenia. |
2017-09-19 |
2023-08-13 |
mouse |
| Dan Madularu, Praveen Kulkarni, Jason R Yee, William M Kenkel, Waqqas M Shams, Craig F Ferris, Wayne G Brak. High estrogen and chronic haloperidol lead to greater amphetamine-induced BOLD activation in awake, amphetamine-sensitized female rats. Hormones and behavior. vol 82. 2017-09-07. PMID:27154458. |
high 17β-estradiol replacement and chronic haloperidol treatment showed increased bold activity in regions of interest and neural networks associated with schizophrenia (hippocampal formations, habenula, amygdala, hypothalamus etc. |
2017-09-07 |
2023-08-13 |
rat |
| N Okada, M Fukunaga, F Yamashita, D Koshiyama, H Yamamori, K Ohi, Y Yasuda, M Fujimoto, Y Watanabe, N Yahata, K Nemoto, D P Hibar, T G M van Erp, H Fujino, M Isobe, S Isomura, T Natsubori, H Narita, N Hashimoto, J Miyata, S Koike, T Takahashi, H Yamasue, K Matsuo, T Onitsuka, T Iidaka, Y Kawasaki, R Yoshimura, Y Watanabe, M Suzuki, J A Turner, M Takeda, P M Thompson, N Ozaki, K Kasai, R Hashimot. Abnormal asymmetries in subcortical brain volume in schizophrenia. Molecular psychiatry. vol 21. issue 10. 2017-09-05. PMID:26782053. |
compared with controls, patients with schizophrenia demonstrated smaller bilateral hippocampus, amygdala, thalamus and accumbens volumes as well as intracranial volume, but larger bilateral caudate, putamen, pallidum and lateral ventricle volumes. |
2017-09-05 |
2023-08-13 |
Not clear |
| N Okada, M Fukunaga, F Yamashita, D Koshiyama, H Yamamori, K Ohi, Y Yasuda, M Fujimoto, Y Watanabe, N Yahata, K Nemoto, D P Hibar, T G M van Erp, H Fujino, M Isobe, S Isomura, T Natsubori, H Narita, N Hashimoto, J Miyata, S Koike, T Takahashi, H Yamasue, K Matsuo, T Onitsuka, T Iidaka, Y Kawasaki, R Yoshimura, Y Watanabe, M Suzuki, J A Turner, M Takeda, P M Thompson, N Ozaki, K Kasai, R Hashimot. Abnormal asymmetries in subcortical brain volume in schizophrenia. Molecular psychiatry. vol 21. issue 10. 2017-09-05. PMID:26782053. |
further, we revealed leftward asymmetry for thalamus, lateral ventricle, caudate and putamen volumes, and rightward asymmetry for amygdala and hippocampal volumes in both controls and patients with schizophrenia. |
2017-09-05 |
2023-08-13 |
Not clear |
| Nikkie F M Olde Loohuis, Nael Nadif Kasri, Jeffrey C Glennon, Hans van Bokhoven, Sébastien S Hébert, Barry B Kaplan, Gerard J M Martens, Armaz Aschraf. The schizophrenia risk gene MIR137 acts as a hippocampal gene network node orchestrating the expression of genes relevant to nervous system development and function. Progress in neuro-psychopharmacology & biological psychiatry. vol 73. 2017-08-30. PMID:26925706. |
the schizophrenia risk gene mir137 acts as a hippocampal gene network node orchestrating the expression of genes relevant to nervous system development and function. |
2017-08-30 |
2023-08-13 |
rat |
| Jennifer J Donegan, Daniel J Lodg. Cell-based therapies for the treatment of schizophrenia. Brain research. vol 1655. 2017-08-08. PMID:27544423. |
indeed, schizophrenia patients show dysregulated activity in the hippocampus and prefrontal cortex, two regions known to regulate dopamine neuron activity. |
2017-08-08 |
2023-08-13 |
Not clear |
| Jennifer J Donegan, Daniel J Lodg. Cell-based therapies for the treatment of schizophrenia. Brain research. vol 1655. 2017-08-08. PMID:27544423. |
therefore, it has been hypothesized that restoring interneuron function in the hippocampus and/or prefrontal cortex may be an effective treatment strategy for schizophrenia. |
2017-08-08 |
2023-08-13 |
Not clear |
| Guihu Zhao, Kristina Denisova, Pejman Sehatpour, Jun Long, Weihua Gui, Jianping Qiao, Daniel C Javitt, Zhishun Wan. Fractal Dimension Analysis of Subcortical Gray Matter Structures in Schizophrenia. PloS one. vol 11. issue 5. 2017-07-07. PMID:27176232. |
we found a significant reduction of fd in the left hippocampus (median: 2.1460, range: 2.07-2.18 vs. median: 2.1730, range: 2.15-2.23, p<0.001; cohen's effect size, u3 = 0.8158 (95% confidence intervals, cis: 0.6316, 1.0)), the right hippocampus (median: 2.1430, range: 2.05-2.19 vs. median: 2.1760, range: 2.12-2.21, p = 0.004; u3 = 0.8421 (cis: 0.5263, 1)), as well as left thalamus (median: 2.4230, range: 2.40-2.44, p = 0.005; u3 = 0.7895 (cis: 0.5789, 0.9473)) in schizophrenia patients, relative to healthy individuals. |
2017-07-07 |
2023-08-13 |
Not clear |
| Guihu Zhao, Kristina Denisova, Pejman Sehatpour, Jun Long, Weihua Gui, Jianping Qiao, Daniel C Javitt, Zhishun Wan. Fractal Dimension Analysis of Subcortical Gray Matter Structures in Schizophrenia. PloS one. vol 11. issue 5. 2017-07-07. PMID:27176232. |
our findings provide in-vivo quantitative evidence for reduced surface complexity of hippocampus, with reduced fd indicating a less complex, less regular gm surface detected in schizophrenia. |
2017-07-07 |
2023-08-13 |
Not clear |
| Nina Vanessa Kraguljac, David Matthew White, Nathan Hadley, Jennifer Ann Hadley, Lawrence Ver Hoef, Ebony Davis, Adrienne Carol Laht. Aberrant Hippocampal Connectivity in Unmedicated Patients With Schizophrenia and Effects of Antipsychotic Medication: A Longitudinal Resting State Functional MRI Study. Schizophrenia bulletin. vol 42. issue 4. 2017-06-30. PMID:26873890. |
aberrant hippocampal connectivity in unmedicated patients with schizophrenia and effects of antipsychotic medication: a longitudinal resting state functional mri study. |
2017-06-30 |
2023-08-13 |
human |
| Peter Falkai, Berend Malchow, Katharina Wetzestein, Verena Nowastowski, Hans-Gert Bernstein, Johann Steiner, Thomas Schneider-Axmann, Theo Kraus, Alkomiet Hasan, Bernhard Bogerts, Christoph Schmitz, Andrea Schmit. Decreased Oligodendrocyte and Neuron Number in Anterior Hippocampal Areas and the Entire Hippocampus in Schizophrenia: A Stereological Postmortem Study. Schizophrenia bulletin. vol 42 Suppl 1. 2017-06-30. PMID:27460617. |
decreased oligodendrocyte and neuron number in anterior hippocampal areas and the entire hippocampus in schizophrenia: a stereological postmortem study. |
2017-06-30 |
2023-08-13 |
Not clear |
| Peter Falkai, Berend Malchow, Katharina Wetzestein, Verena Nowastowski, Hans-Gert Bernstein, Johann Steiner, Thomas Schneider-Axmann, Theo Kraus, Alkomiet Hasan, Bernhard Bogerts, Christoph Schmitz, Andrea Schmit. Decreased Oligodendrocyte and Neuron Number in Anterior Hippocampal Areas and the Entire Hippocampus in Schizophrenia: A Stereological Postmortem Study. Schizophrenia bulletin. vol 42 Suppl 1. 2017-06-30. PMID:27460617. |
the hippocampus is involved in cognition as well as emotion, with deficits in both domains consistently described in schizophrenia. |
2017-06-30 |
2023-08-13 |
Not clear |
| Peter Falkai, Berend Malchow, Katharina Wetzestein, Verena Nowastowski, Hans-Gert Bernstein, Johann Steiner, Thomas Schneider-Axmann, Theo Kraus, Alkomiet Hasan, Bernhard Bogerts, Christoph Schmitz, Andrea Schmit. Decreased Oligodendrocyte and Neuron Number in Anterior Hippocampal Areas and the Entire Hippocampus in Schizophrenia: A Stereological Postmortem Study. Schizophrenia bulletin. vol 42 Suppl 1. 2017-06-30. PMID:27460617. |
in this design-based stereological study of the anterior part of the hippocampus comparing 10 patients with schizophrenia to 10 age- and gender-matched healthy controls were examined. |
2017-06-30 |
2023-08-13 |
Not clear |
| Yutaka Nakagawa, Kenji Chib. Involvement of Neuroinflammation during Brain Development in Social Cognitive Deficits in Autism Spectrum Disorder and Schizophrenia. The Journal of pharmacology and experimental therapeutics. vol 358. issue 3. 2017-05-26. PMID:27384073. |
by contrast, schizophrenia seems to be triggered by thalamic hyperactivation in late adolescence, whereas hippocampal aberration has been possibly initiated in childhood. |
2017-05-26 |
2023-08-13 |
Not clear |
| Martin Hýža, Matyáš Kuhn, Eva Češková, Libor Ustohal, Tomáš Kašpáre. Hippocampal volume in first-episode schizophrenia and longitudinal course of the illness. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 17. issue 6. 2017-05-24. PMID:27403591. |
hippocampal volume in first-episode schizophrenia and longitudinal course of the illness. |
2017-05-24 |
2023-08-13 |
Not clear |
| Christian Knöchel, Jonathan Kniep, Jason D Cooper, Michael Stäblein, Sofia Wenzler, Jan Sarlon, David Prvulovic, David E J Linden, Sabine Bahn, Pawel Stocki, Sureyya Ozcan, Gilberto Alves, Andre F Carvalho, Andreas Reif, Viola Oertel-Knöche. Altered apolipoprotein C expression in association with cognition impairments and hippocampus volume in schizophrenia and bipolar disorder. European archives of psychiatry and clinical neuroscience. vol 267. issue 3. 2017-03-29. PMID:27549216. |
altered apolipoprotein c expression in association with cognition impairments and hippocampus volume in schizophrenia and bipolar disorder. |
2017-03-29 |
2023-08-13 |
Not clear |
| Cunyan Li, Yamei Tang, Jingjing Yang, Xianghui Zhang, Yong Liu, Aiguo Tan. Sub-chronic Antipsychotic Drug Administration Reverses the Expression of Neuregulin 1 and ErbB4 in a Cultured MK801-Induced Mouse Primary Hippocampal Neuron or a Neurodevelopmental Schizophrenia Model. Neurochemical research. vol 41. issue 8. 2017-03-03. PMID:27097547. |
sub-chronic antipsychotic drug administration reverses the expression of neuregulin 1 and erbb4 in a cultured mk801-induced mouse primary hippocampal neuron or a neurodevelopmental schizophrenia model. |
2017-03-03 |
2023-08-13 |
mouse |